Pavel Smirnov, CEO of Health Samurai, organized the inaugural FHIR meetup at UC San Diego to discuss developing FHIR-first applications. Health Samurai's Aidbox is a FHIR development platform that allows building applications using the FHIR standard and data model. Aidbox provides tools like a FHIR API and storage, as well as the ability to extend the FHIR model to support custom use cases. Lessons from using FHIR include benefits like standardized data models and an active community, as well as challenges in migrating between versions and complexity of extensions.