Zerachiah ha-Levi of Girona was a famous 12th century rabbi, Torah and Talmud commentator, and poet born in 1125 in Girona, Spain. Judah Halevi was an influential 11th-12th century Spanish Jewish physician, poet, and philosopher born in either Toledo or Tudela, Spain who died in 1141 in Palestine. Maimonides was a prominent 12th-13th century Sephardic Jewish philosopher, astronomer, and physician born in 1135 or 1138 in Cordoba, Almoravid Empire who died in 1204 in Egypt. Isaac Israeli ben Joseph, a 14th century Spanish-Jewish astronomer/astrolog
Abu Yūsuf Yaʻqūb ibn ʼIsḥāq aṣ-Ṣabbāḥ al-Kindī was an Arab Muslim philosopher, polymath, mathematician, physician and musician. Al-Kindi was the first of the Islamic peripatetic philosophers, and is hailed as the "father of Arab philosophy".
This article examines the life and work of 13th century scholar, polymath and politician Nasir al-Din Tusi, as well as a comparative analysis of his philosophical views on public administration issues of the peripatetic philosopher Farabi’s views on the state and private property.
Highlights on some of the Muslim Scholars’ Contributions in the Science of Management .
By
Yaser Zakariyya Alhindi
MGT 501 Project – 2012
MBA Program – KFUPM
Yaser.Alhindi@gmail.com
This was used for Lit 209 (Afro-Asian Literature).
This presentation is divided into 4 parts (Israel, Hebrew Literature, The Bible and some Biblical pieces).
Also includes some notes within the presentation itself.
Abu Yūsuf Yaʻqūb ibn ʼIsḥāq aṣ-Ṣabbāḥ al-Kindī was an Arab Muslim philosopher, polymath, mathematician, physician and musician. Al-Kindi was the first of the Islamic peripatetic philosophers, and is hailed as the "father of Arab philosophy".
This article examines the life and work of 13th century scholar, polymath and politician Nasir al-Din Tusi, as well as a comparative analysis of his philosophical views on public administration issues of the peripatetic philosopher Farabi’s views on the state and private property.
Highlights on some of the Muslim Scholars’ Contributions in the Science of Management .
By
Yaser Zakariyya Alhindi
MGT 501 Project – 2012
MBA Program – KFUPM
Yaser.Alhindi@gmail.com
This was used for Lit 209 (Afro-Asian Literature).
This presentation is divided into 4 parts (Israel, Hebrew Literature, The Bible and some Biblical pieces).
Also includes some notes within the presentation itself.
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
This presentation explores a brief idea about the structural and functional attributes of nucleotides, the structure and function of genetic materials along with the impact of UV rays and pH upon them.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
PRESENTATION ABOUT PRINCIPLE OF COSMATIC EVALUATION
Halacha date line 01 sources
1.
2. Rishonim
ראשוניםZerachiah ha-Levi of Girona
From Wikipedia, the free encyclopedia
Zerachiah ben Isaac ha-Levi Gerondi (Hebrew: הלוי זרחיה), called the ReZaH, RaZBI or Baal Ha-Maor (author of the book
Ha-Maor) was born about 1125 in the town of Girona, Spain – hence the name Gerondi – and died after 1186 in Lunel. He
was a famous rabbi, Torah and Talmud commentator and a poet.
From Wikipedia, the free encyclopedia
Judah Halevi (also Yehuda Halevi or ha-Levi;
c. 1075 – 1141) was a Spanish Jewish
physician, poet and philosopher. He was born in
Spain, either in Toledo or Tudela, in 1075 or
1086, and died shortly after arriving in Palestine
in 1141, at that point the Crusader Kingdom of
Jerusalem. Halevi is considered one of the
greatest Hebrew poets, celebrated both for his
religious and secular poems, many of which
appear in present-day liturgy. His greatest
philosophical work was The Kuzari.
3. Rishonim
ראשונים
Maimonides
From Wikipedia, the free encyclopedia
Moshe ben Maimon (Hebrew: מימון בן משה Moshe ben Maymon), Moses Maimonides, a preeminent medieval Sephardic Jewish
philosopher and astronomer, became one of the most prolific and influential Torah scholars and physicians of the Middle Ages. Born in
Cordova (present-day Spain), Almoravid Empire on Passover Eve, 1135 or 1138,he died in Egypton December 12, 1204, whence his
body was taken to the lower Galilee and buried in Tiberias. He worked as a rabbi,physician, and philosopher in Morocco and Egypt.
4. Rishonim
ראשונים
Yesod Olam (1777 edition), title page.
It treats of geometry and trigonometry as introductory to the
subject-matter; of the structure and position of the globe; of
the number and movements of the celestial spheres; of the
time differences in days and nights in the various parts of the
earth; of the movements of sun and moon; of the solstices, the
neomeniæ, the eclipses, and the leap-years; it contains as well
astronomical tables (an ephemeris) and a perpetual calendar. It
also deals (iv, § 17) with the chronological systems of other
nations and religions, especially Christianity; and gives (iv, § 18)
in chronological order the noted personages of the Biblical,
Talmudic, and geonic periods, following the Sefer ha-Qabbalah
ofAbraham ibn Daud. This last was included by Zacuto in his
Sefer ha-Yuḥasin.
Isaac Israeli ben Joseph or Yitzhak ben
Yosef (often known as Isaac Israeli the
Younger) was a Spanish-Jewish
astronomer/astrologer who flourished at
Toledo in the first half of the fourteenth
century. He was a pupil of Asher ben Yehiel,
at whose request (in 1310) he wrote the
astronomical work Yesod Olam, the best
contribution on that subject to Hebrew
literature.
5. Acharonim
אחרונים
When the Nazi extermination under Adolf Hitler advanced through Europe, men from the Slobodka and Chachmei Lublin
yeshivot journeyed Eastward towards the Far East to survive and flourish in Shanghai and in Kobe, Japan.
When it came time to observe Yom Kippur during the War years, (and the logic also follows for all the holidays and
Shabbat), the men of these yeshivot turned towards two Torah greats, Gedolei Hatorah, for guidance.
Avrohom Yeshaya
Karelitz, (7 November
1878 – 24 October 1953),
popularly known by the
name of his magnum
opus, Chazon Ish, was a
Belarusian born Orthodox
rabbi who later became
one of the leaders of
Haredi Judaism in Israel,
where his final 20 years,
from 1933 to 1953, were
spent.
Yechiel Michael
Tukachinsky
b. 27 December 1871
- March 31, 1955)
was head and
director of Yeshiva
"Etz Chaim", the
father of the “Eretz
Yisrael Calendar" and
the author of many
halachic books.
6. Rabbi Dr. Aharon Chaim Zimmerman (1914– march 9, 1995) (7th Adar
II 5755) was one of the leading rabbis of the Post-War generation. He
was the son of Rabbi Yaakov Moshe Zimmerman and nephew of Rabbi
Baruch Ber Lebowitz. He was born in Konotop, Ukraine, and studied
under a private tutor until his bar mitzva. He was known as a child
prodigy ("illui") and as a teen-ager attended the Kaminetz Yeshiva
headed by his uncle the renowned Rabbi Baruch Ber Lebowitz. He left
Russia at age 15 with his father and immigrated to the U.S., and taught
a Talmud class at RIETS. He received rabbinical ordination from
Rabbi Moshe Soloveitchik in 1939. His first published work "Binyan
Halakha" contains a letter of approbation from the Chief Rabbi of Eretz
Israel Rabbi Yitzchak Halevi Herzog attesting that the young author was
"fully knowledgeable in the entire Talmud Bavli and
Yerushalmi,Rishonim and Achronim."
He served as Rosh Yeshiva of Hebrew Theological College in Chicago
until 1964, and later a Rosh Yeshiva in New York City and in Jerusalem.
He immigrated to Israel in 1972. He died on march 9, 1995. (7th Adar II
5755)[1]
He published several books on Halacha and Philosophy. He was
renowned as a genius in Torah learning, and was also well versed in
mathematics, physics, and philosophy. In the early 1950s when
the halachic status of the 'international dateline' was the subject of
considerable debate, he published his best known work 'Agan HaSahar'.
Acharonim
אחרונים
10. (Mouse over the picture)
At the bottom of this slide there is an audio
clip and a pointer that will explain this picture.
Mouse over the bottom to find and play the
clip.