Green Tea : A promising natural product in oral health

1.  GREEN TEAGREEN TEA::
AA
PROMISINGPROMISING
NATURAL PRODUCTNATURAL PRODUCT
IN ORAL HEALTHIN ORAL HEALTH

2. CamelliaCamellia
sinensissinensis

3.  The appearance of green tea in three different stages (from left toThe appearance of green tea in three different stages (from left to
right): the infused leaves, the dry leaves and the liquid. Noticeright): the infused leaves, the dry leaves and the liquid. Notice
that the infused leaves look greener than the dry leaves.that the infused leaves look greener than the dry leaves.

6. GREEN TEA in combating DENTAL CARIESGREEN TEA in combating DENTAL CARIES
 Magalahaes et al found that mouth rinsing with green teaMagalahaes et al found that mouth rinsing with green tea
extract(0.61%)protect from erosion and abrasion similar toextract(0.61%)protect from erosion and abrasion similar to
chlorhexidine extract(0.06%)chlorhexidine extract(0.06%)
 In addition one week of mouthwash with green tea(1.6 g of greenIn addition one week of mouthwash with green tea(1.6 g of green
tea in 40 ml water 3 times a day) was able to reduce the salivarytea in 40 ml water 3 times a day) was able to reduce the salivary
levels of cariogenic pathogen such as streptococcus mutants andlevels of cariogenic pathogen such as streptococcus mutants and
lactobacillilactobacilli
 In an study it cause reduction in acid production and impaired phIn an study it cause reduction in acid production and impaired ph
decrease by a mechanism inhibiting the enzymes lactatedecrease by a mechanism inhibiting the enzymes lactate
dehydrogenase that leads to the formation of lactic acid fromdehydrogenase that leads to the formation of lactic acid from
pyruvatepyruvate
 Green tea polyphenols significantly blocked the adhesion of oralGreen tea polyphenols significantly blocked the adhesion of oral
bacteria in glycoproetin layer in a model that stimulated defensivebacteria in glycoproetin layer in a model that stimulated defensive
salivasaliva

7. ANTIVIRAL PROPERIESANTIVIRAL PROPERIES
 Polyphenol act as an antioxidants, inhibit enzymes thatPolyphenol act as an antioxidants, inhibit enzymes that
damage cellular membranes and prevent binding anddamage cellular membranes and prevent binding and
prevention of virus to cells.prevention of virus to cells.
 Green tea may encounter various viruses which areGreen tea may encounter various viruses which are
found in the oral cavity.found in the oral cavity.
 ECGC prevents infection from influenza virus byECGC prevents infection from influenza virus by
attaching to viral haemagglutinin.attaching to viral haemagglutinin.
 Green tea can also interfere the mechanism of HIV-1,Green tea can also interfere the mechanism of HIV-1,
HSV-1,adenovirus,Epstein barr virus and more.HSV-1,adenovirus,Epstein barr virus and more.

8. Abolition Of HalitosisAbolition Of Halitosis
 Lodhia et al. found that green tea powder succeeded toLodhia et al. found that green tea powder succeeded to
abate the creation of those sulphur compounds andabate the creation of those sulphur compounds and
consequently halitosis for an hour.consequently halitosis for an hour.
 Zeng et al. demonstrated that green tea extract wasZeng et al. demonstrated that green tea extract was
able to remove the odorant sulphurs.able to remove the odorant sulphurs.
 Few of mouth spray and chewin gum contain teaFew of mouth spray and chewin gum contain tea
polyphenols.polyphenols.

9. Protection from Oral OxidativeProtection from Oral Oxidative
stress and Cigarette smoke inducedstress and Cigarette smoke induced
inflammationinflammation
 Maruyama et al. have shown green tea catechin effect in reduction ofMaruyama et al. have shown green tea catechin effect in reduction of
gingival oxidative stress.gingival oxidative stress.
 Cigarette smoke destroys oral cavity homeostasis. It decreases salivaryCigarette smoke destroys oral cavity homeostasis. It decreases salivary
antioxidant status, initiate oral inflammatory disease and promote oralantioxidant status, initiate oral inflammatory disease and promote oral
malignancies.malignancies.
 Green tea catechins have ability to scavenge Nitric oxide, superoxideGreen tea catechins have ability to scavenge Nitric oxide, superoxide
oxide ,in addition ECGC also suppresses NF-kB activation by preventingoxide ,in addition ECGC also suppresses NF-kB activation by preventing
the phosphorylation and breakdown of inhibitory IkB-the phosphorylation and breakdown of inhibitory IkB-α in human pulpα in human pulp
cells.cells.
 Cigarette contains more than 4700 chemical compound out of themCigarette contains more than 4700 chemical compound out of them
Nicotine and Acrolein causes gingivitis and periodontitis.also nicotine is aNicotine and Acrolein causes gingivitis and periodontitis.also nicotine is a
potent carcinogen.potent carcinogen.
 ECGC may be helpful to reduce ACROLEIN damages as they quenchECGC may be helpful to reduce ACROLEIN damages as they quench
ACROLEIN and other unsaturated aldehydes.ACROLEIN and other unsaturated aldehydes.
 Thus green tea drinking may reduce cigarette smoking oxidative andThus green tea drinking may reduce cigarette smoking oxidative and
inflammatory damages to oral cavity.inflammatory damages to oral cavity.

10. Protection from Oral Oxidative stress andProtection from Oral Oxidative stress and
Cigarette smoke induced inflammationCigarette smoke induced inflammation

11. Oral malignancyOral malignancy
prevention and regressionprevention and regression
 Tea extracts or ECGC protected against chemicalTea extracts or ECGC protected against chemical
carcinogens in several organs such ascarcinogens in several organs such as
intestine,lung,liver,prostrate,breast and mouth.intestine,lung,liver,prostrate,breast and mouth.
 In rats, oral cancer was induced by 4-Nitroquinoline-1-In rats, oral cancer was induced by 4-Nitroquinoline-1-
oxide.They have been given green tea polyphenolsoxide.They have been given green tea polyphenols
extracts. The number and volume of tumours wereextracts. The number and volume of tumours were
smaller on the average compared with rats that did notsmaller on the average compared with rats that did not
receive green tea.receive green tea.
 Tea polyphenols may induce apoptosis and cell cycleTea polyphenols may induce apoptosis and cell cycle
delay in tumour cells but not in the normal cells thusdelay in tumour cells but not in the normal cells thus
affecting number of biological pathways.affecting number of biological pathways.

12. Green Tea Side EffectsGreen Tea Side Effects
 The green tea is generally free of any side effects. However,The green tea is generally free of any side effects. However,
pregnant women are advised to reduce their intake duringpregnant women are advised to reduce their intake during
pregnancy as it was found in different research studies that thepregnancy as it was found in different research studies that the
EGCG will affect the way folate is used by the body. This elementEGCG will affect the way folate is used by the body. This element
is of extreme implication for pregnant women, since it checksis of extreme implication for pregnant women, since it checks
neural tube birth defects in newborns.neural tube birth defects in newborns.
 The medical fraternity is of the opinion however, that there isThe medical fraternity is of the opinion however, that there is
some amount of caffeine in green tea, which sometimes triggerssome amount of caffeine in green tea, which sometimes triggers
insomnia just like coffee .insomnia just like coffee .
 Too much caffeine can cause nausea, insomnia or frequentToo much caffeine can cause nausea, insomnia or frequent
urination.urination.
 Scientists have warned the users that intake this tea in largeScientists have warned the users that intake this tea in large
amounts can pose danger to the kidney as well as the liver inamounts can pose danger to the kidney as well as the liver in
some indivisual.some indivisual.

13. THANK YOU…THANK YOU…