Google Adwords allows advertisers to create campaigns, ad groups, keywords, and ads. Campaigns are responsible for budget and targeting. Ad groups contain 5-10 closely related keywords that receive the same ads. Ads should match keywords and direct users to relevant landing pages. Advertisers should aim for a high quality score to lower costs and increase impressions. Keywords are structured as broad, phrase, or exact match and negative keywords exclude unwanted searches. Metrics like CTR, CPC, and conversions should be monitored and keywords, ads and landing pages optimized over time.