Gonorrhea is caused by the bacteria Neisseria gonorrhoeae. It primarily infects the genital tract and rectum through sexual contact. Common symptoms in males include painful urination and discharge from the penis. In females, gonorrhea often shows few or no symptoms but can cause pelvic inflammatory disease if untreated. Diagnosis is made through microscopic examination of discharge, culture growth on selective media, and demonstration of intracellular diplococci on gram stain. Treatment involves antibiotics such as ceftriaxone or ciprofloxacin.
2. Etio
• caused by gram –ve diplocoocus nisseria
Gonorrhea(gonococcus)
• Length 1.2 -1.6 micro m
• Effects columnar cells
• Have L forms
• Beta lactamase producing forms
• Intercellular localization
3. Loc
• In males : urethra littre’s area and cowper’s
glands prostrate seminal veicles and
epidydimis
• In females: urethra bartholin’s g;ands and
skene’s gland cervix and fallopian tubes
• Extragenital sites : rectum .conjuctiva and
pharynx
4. transmission
• Sexual contact
• Close contact
• Vertical transmission
• Auto inoculation (transmission of infection to
eyes by hands)
5. classification
• Based on localization
• A)on inferior parts of urogenital tract without
complications
• B) on inferior parts of urogenital tract with
complications
• C)on superior part of urogenital tract and
pelvic area organs
• D)on other organs (rectum pharynx eye’s)
6. • Based on course
• A) fresh :before 2 months
• Acute
• Sub acute
• Tropid
• B)chronic after 2 months
• C)latent
• D) carrage of gonccocal
7. Anterior acute urethritis : painful, dysuria on
mituration. Profuse prulent discharges
,.hyperemia ,edema of the lips of urethra
.often occurs 3-5 days after ineter course for
tropical diag 2 glasses tampon test used.
If the urine is turbid in the first glass ,then its inf
of anterior part of urethra if turbid in both the
glasses then all the parts of urethra.
8. • Sub acute urethritis: hyperemia,painless than
acute process samm muco prulent discharge
• Tropid : sluding of urethral lips , small muco
prulent discharge freqent mituration
increased pian
• Cowperitis : inf of bulbourethral glands severe
and dull pain , perineum (rectal exam) on
pa;pation large and painfull proctate in acute
stage fever chills dysuria
9. • Chronic : toprid latent course inflmation of
urethral glands
• Proctatis : inflamation of the anus and lining
of rectum affects only last six inches of rectum
• A) catarrhal
• B) follicular
• C) parynchymatous
• Epididimitis
10. In females
• Its charetesied by polyfocal,asymtomatic
latent course:
• 1.desending
• A)urethritis
• B)bartholinitis
• C)vestubulitis
• D)cervicitis
• E)endocevicitis
11. • Ascending
• A) endo metritis
• B) metro endometritis
• C)salpingitis
• D) salpingo oophoritis
• E)pelvio peritonitis
12. Children
• Gonoblenorrhoea: during delivery of child and
effets conjuctiva of eyes
• Vulvo vaginitis it is transmitted by close
contact and during delivery
• Extra genital
• Proctitis
• Oropharengeal
• Conjuctivitis
13. • Smear examination : urethral and endo
cervical discharge ,pharyngeal and rectal
swabs .
• Culture
• 2types of media
• Non selctive media : choclate agar
• Selective :thayer –martin and chaco –nair
medium.
14. • Based on c/f
• Short incubation 1-5 dys
• Profuse thick creamy discharge
• Demonstration of icdc(Intra cellular
diploccoci) on gram stain
• Dif diaf from clamydia longer incubation
mucoid dischrge only plymorphs in urethral
smear <<< 1-5 profuse creamy dischrge icdc.
15. 2 glasses tampon test used.
If the urine is turbid in the first glass ,then its inf
of anterior part of urethra if turbid in both the
glasses then all the parts of urethra.
16. Treatment
• General measures : sexual abstinence
• treatment of sexual partners
• Avoidance of heavy work
• Avoidance of alcohol
• Acute
• Ant b : procine pen ceftriaxone ampicillin ciprofloxicin
spectinomycin pen drps for gonococcalconjuctivitis
• Chronic
• Immunotherapy
• Ant b s amides
• Non specfi : vitamins enzyes aloe symptomatic
• Physio thrpy (us diathermia electro phono phoresis)
• Topical wasing of vagina suppository vagial n urethra
irrigation sawab in vag