El documento habla sobre la seguridad informática. Define un sistema informático como el conjunto de hardware, software, datos y usuarios que permiten el procesamiento automático de datos. Explica que la información es un activo estratégico que debe protegerse de amenazas como alteraciones, destrucción o mal uso. Resume los principios, factores de riesgo y mecanismos de seguridad informática.
Stumbling through the fog: A lived experience of fibromyalgiaSimon R. Stones
This presentation was delivered as part of the ME, CFS and Fibromyalgia Alliance Malta VO/818 and European Network of Fibromyalgia Associations (ENFA) Conference held on Saturday 12 May 2018 in Attard, Malta. The conference was opened by Her Excellency, President Marie Louise Coleiro Preca.
The document discusses end-of-life care for pediatric oncology patients, including an overview of treatments like chemotherapy and radiation. It then covers the process of death and available palliative care resources. Key perspectives discussed include those of patients, parents, siblings, and hospital staff.
The document discusses principles of cancer management and treatment options. It outlines current standard treatments like surgery, radiotherapy, and chemotherapy. It also discusses newer treatments and the process of clinical trials, from phase 1 safety trials to phase 3 trials that compare new treatments to standard therapies. An example is given of problems that can occur in phase 3 trials if factors like surgical debulking are not properly controlled for. Complementary treatments are discussed, along with examples of treatments that originated from plant and animal extracts.
This document summarizes JDRF's work towards curing, treating, and preventing type 1 diabetes. It discusses JDRF's goals of developing life-changing therapies through research, clinical development, and regulatory work. This includes work towards developing an artificial pancreas through improved glucose sensors and control software. The document also discusses current challenges in treating type 1 diabetes, like increasing rates of hypoglycemia and poor glucose control. JDRF is working on various approaches to cure diabetes through islet and stem cell transplantation, regenerating beta cells, and preventing diabetes onset through vaccines and beta cell survival agents.
The document discusses treatments for overactive and underactive thyroid conditions. The main treatments described are antithyroid medications like carbimazole and propylthiouracil, radioactive iodine treatment, and surgery to remove part or all of the thyroid gland. It also discusses lifelong levothyroxine treatment for an underactive thyroid and monitoring of hormone levels through blood tests to ensure the correct levothyroxine dose is taken. Side effects of treatments are also summarized.
El documento habla sobre la seguridad informática. Define un sistema informático como el conjunto de hardware, software, datos y usuarios que permiten el procesamiento automático de datos. Explica que la información es un activo estratégico que debe protegerse de amenazas como alteraciones, destrucción o mal uso. Resume los principios, factores de riesgo y mecanismos de seguridad informática.
Stumbling through the fog: A lived experience of fibromyalgiaSimon R. Stones
This presentation was delivered as part of the ME, CFS and Fibromyalgia Alliance Malta VO/818 and European Network of Fibromyalgia Associations (ENFA) Conference held on Saturday 12 May 2018 in Attard, Malta. The conference was opened by Her Excellency, President Marie Louise Coleiro Preca.
The document discusses end-of-life care for pediatric oncology patients, including an overview of treatments like chemotherapy and radiation. It then covers the process of death and available palliative care resources. Key perspectives discussed include those of patients, parents, siblings, and hospital staff.
The document discusses principles of cancer management and treatment options. It outlines current standard treatments like surgery, radiotherapy, and chemotherapy. It also discusses newer treatments and the process of clinical trials, from phase 1 safety trials to phase 3 trials that compare new treatments to standard therapies. An example is given of problems that can occur in phase 3 trials if factors like surgical debulking are not properly controlled for. Complementary treatments are discussed, along with examples of treatments that originated from plant and animal extracts.
This document summarizes JDRF's work towards curing, treating, and preventing type 1 diabetes. It discusses JDRF's goals of developing life-changing therapies through research, clinical development, and regulatory work. This includes work towards developing an artificial pancreas through improved glucose sensors and control software. The document also discusses current challenges in treating type 1 diabetes, like increasing rates of hypoglycemia and poor glucose control. JDRF is working on various approaches to cure diabetes through islet and stem cell transplantation, regenerating beta cells, and preventing diabetes onset through vaccines and beta cell survival agents.
The document discusses treatments for overactive and underactive thyroid conditions. The main treatments described are antithyroid medications like carbimazole and propylthiouracil, radioactive iodine treatment, and surgery to remove part or all of the thyroid gland. It also discusses lifelong levothyroxine treatment for an underactive thyroid and monitoring of hormone levels through blood tests to ensure the correct levothyroxine dose is taken. Side effects of treatments are also summarized.
Tibolone 2.5mg tablets pil, taj pharmaceuticals.Taj Pharma
Tibolone 2.5mg Tablets Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Tibolone Dosage & Rx Info | Tibolone Uses, Side Effects , Tibolone 2.5mg Tablets: Indications, Side Effects, Warnings, Tibolone - Drug Information - Taj Pharma, Tibolone dose Taj pharmaceuticals Tibolone interactions, Taj Pharmaceutical Tibolone contraindications, Tibolone price, Tibolone , Taj Pharma Tibolone 2.5mg Tablets - Taj Pharma . Stay connected to all updated on Tibolone Taj Pharmaceuticals Taj pharmaceuticals Hyderabad. Patient Information Leaflets, PIL.
This document presents a case report of a 50-year-old male farmer who was admitted to the hospital with symptoms of tetanus. He had sustained a deep cut on his right calf while working in his field one week prior that had been sutured at a local health center. On admission, he exhibited stiffness of the neck muscles and inability to open his mouth. He was diagnosed with tetanus and admitted to the intensive care unit for management. Treatment included wound debridement, antibiotics, tetanus immunoglobulin, sedation and muscle relaxants. Tetanus is a vaccine-preventable neurological disease caused by Clostridium tetani spores entering the body through wounds. It causes painful muscle
Tuberculosis, or TB, is caused by bacteria that usually affect the lungs. It can be spread through the air when someone with active TB coughs or sneezes. There are two types of TB infection - latent TB, where the bacteria remain inactive in the body, and active TB, where the bacteria are causing symptoms and can be transmitted. To prevent the spread of TB, it is important to avoid exposure to those with active infections, get tested if exposed, and begin treatment right away if diagnosed with latent TB.
We know that mesothelioma patients would rather stay local when receiving treatment,rnso we will review options for private medical centers, surgical consultants, clinical trials,rnand match you up with friendly, local physicians wherever we can.
There are two main approaches to treating trichotillomania: medication and behavioral therapy. Medication alone, such as antidepressants, has shown low success rates. The most effective treatment is behavioral therapy like habit reversal training, which teaches patients to monitor their hair pulling and replace it with healthier habits. This type of therapy has shown success rates over 90%. Alternative therapies may include hypnosis or biofeedback.
This document discusses several ethical dilemmas that can arise at the end of life. It describes situations involving conflicts between clinicians and families over appropriate care, as well as conflicts within clinical teams. It also addresses issues around withdrawing or withholding treatment, physician assisted suicide, palliative sedation, and ensuring comfort at end of life. The document emphasizes the importance of open communication, establishing goals of care based on patient values and preferences, and providing care aimed at both cure and comfort.
What has been learned from the major observationalfalcaoebarros
The document discusses 4 main lessons learned from major observational studies and clinical trials on hormonal treatments: 1) Progestagens may suppress some benefits of estrogens and slightly increase breast cancer risk with long-term use; 2) Estrogens alone did not increase breast cancer risk; 3) Metabolic effects of hormones differ by route and regimen; 4) Hormones are effective for vasomotor symptoms but not secondary cardiovascular prevention. It also discusses the need for evidence-informed practice over strictly evidence-based medicine and emphasizes balancing risks and benefits of treatments tailored to individual needs and preferences.
Our alternative 3E – Program is based on what people have actually done to survive cancer. We have learned from them and have incorporated this knowledge into our 3E program. Treating cancer with alternative strategies and without chemotherapy has become a possibility for an ever-increasing number of people.
Dr Pompa - The Missing Strategy to Stay Lean and Healthy: Not Only Missed, Bu...DwightVillos
This document discusses the hidden causes of modern health issues like autism, dementia, thyroid problems, and chronic fatigue. It argues that environmental toxins like pesticides, mercury, lead, and glyphosate are overwhelming the body and disrupting hormones. These toxins can pass from mother to baby for four generations and trigger genetic susceptibility. Weight gain and hormone resistance are linked to cellular inflammation from toxins. True detox must occur at the cellular level. A conference is promoted to discuss health centers of the future focused on real detox at the cellular level.
This document provides guidance on assessing and managing a poisoned child. It discusses the common causes of pediatric poisoning, important clinical assessments like vital signs and physical exam findings, key investigations like lab tests and toxicology screens, and general treatment approaches focusing on supportive care, decontamination, enhanced elimination, and antidotes. The toxidromes of various substance classes are also reviewed to help identify the potential toxin. A thorough history and physical exam tailored to potential exposures is emphasized for diagnosis and management of the poisoned child.
Methods of life extension currently availabelavturchin
This document provides an overview of currently available methods for life extension organized into the following categories: lifestyle changes, social life, ecology, motivation, country of residence, risk reduction, health checks, nutrition, mobility, supplements, sleep, controlling health parameters, hormone therapy, hormesis, medications, medical insurance, brain health, regeneration, cryonics, and maintaining motivation. The document outlines specific actions individuals can take within each category to potentially extend their lifespan based on current scientific research and understanding.
Nano-gold for Cancer Therapy chemistry investigatory projectSIVAVINAYAKPK
chemistry investigatory project
The development of nanogold-based cancer therapy could revolutionize oncology by providing a more targeted, less invasive treatment option. This project contributes to the growing body of research aimed at harnessing nanotechnology for medical applications, paving the way for future clinical trials and potential commercial applications.
Cancer remains one of the leading causes of death worldwide, prompting the need for innovative treatment methods. Nanotechnology offers promising new approaches, including the use of gold nanoparticles (nanogold) for targeted cancer therapy. Nanogold particles possess unique physical and chemical properties that make them suitable for drug delivery, imaging, and photothermal therapy.
STUDIES IN SUPPORT OF SPECIAL POPULATIONS: GERIATRICS E7shruti jagirdar
Unit 4: MRA 103T Regulatory affairs
This guideline is directed principally toward new Molecular Entities that are
likely to have significant use in the elderly, either because the disease intended
to be treated is characteristically a disease of aging ( e.g., Alzheimer's disease) or
because the population to be treated is known to include substantial numbers of
geriatric patients (e.g., hypertension).
Nutritional deficiency Disorder are problems in india.
It is very important to learn about Indian child's nutritional parameters as well the Disease related to alteration in their Nutrition.
Storyboard on Acne-Innovative Learning-M. pharm. (2nd sem.) CosmeticsMuskanShingari
Acne is a common skin condition that occurs when hair follicles become clogged with oil and dead skin cells. It typically manifests as pimples, blackheads, or whiteheads, often on the face, chest, shoulders, or back. Acne can range from mild to severe and may cause emotional distress and scarring in some cases.
**Causes:**
1. **Excess Oil Production:** Hormonal changes during adolescence or certain times in adulthood can increase sebum (oil) production, leading to clogged pores.
2. **Clogged Pores:** When dead skin cells and oil block hair follicles, bacteria (usually Propionibacterium acnes) can thrive, causing inflammation and acne lesions.
3. **Hormonal Factors:** Fluctuations in hormone levels, such as during puberty, menstrual cycles, pregnancy, or certain medical conditions, can contribute to acne.
4. **Genetics:** A family history of acne can increase the likelihood of developing the condition.
**Types of Acne:**
- **Whiteheads:** Closed plugged pores.
- **Blackheads:** Open plugged pores with a dark surface.
- **Papules:** Small red, tender bumps.
- **Pustules:** Pimples with pus at their tips.
- **Nodules:** Large, solid, painful lumps beneath the surface.
- **Cysts:** Painful, pus-filled lumps beneath the surface that can cause scarring.
**Treatment:**
Treatment depends on the severity and type of acne but may include:
- **Topical Treatments:** Such as benzoyl peroxide, salicylic acid, or retinoids to reduce bacteria and unclog pores.
- **Oral Medications:** Antibiotics or oral contraceptives for hormonal acne.
- **Procedures:** Such as chemical peels, extraction of comedones, or light therapy for more severe cases.
**Prevention and Management:**
- **Cleanse:** Regularly wash skin with a gentle cleanser.
- **Moisturize:** Use non-comedogenic moisturizers to keep skin hydrated without clogging pores.
- **Avoid Irritants:** Such as harsh cosmetics or excessive scrubbing.
- **Sun Protection:** Use sunscreen to prevent exacerbation of acne scars and inflammation.
Acne treatment can take time, and consistency in skincare routines and treatments is crucial. Consulting a dermatologist can help tailor a treatment plan that suits individual needs and reduces the risk of scarring or long-term skin damage.
Selective alpha1 blockers are Prazosin, Terazosin, Doxazosin, Tamsulosin and Silodosin majorly used to treat BPH, also hypertension, PTSD, Raynaud's phenomenon, CHF
Tibolone 2.5mg tablets pil, taj pharmaceuticals.Taj Pharma
Tibolone 2.5mg Tablets Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Tibolone Dosage & Rx Info | Tibolone Uses, Side Effects , Tibolone 2.5mg Tablets: Indications, Side Effects, Warnings, Tibolone - Drug Information - Taj Pharma, Tibolone dose Taj pharmaceuticals Tibolone interactions, Taj Pharmaceutical Tibolone contraindications, Tibolone price, Tibolone , Taj Pharma Tibolone 2.5mg Tablets - Taj Pharma . Stay connected to all updated on Tibolone Taj Pharmaceuticals Taj pharmaceuticals Hyderabad. Patient Information Leaflets, PIL.
This document presents a case report of a 50-year-old male farmer who was admitted to the hospital with symptoms of tetanus. He had sustained a deep cut on his right calf while working in his field one week prior that had been sutured at a local health center. On admission, he exhibited stiffness of the neck muscles and inability to open his mouth. He was diagnosed with tetanus and admitted to the intensive care unit for management. Treatment included wound debridement, antibiotics, tetanus immunoglobulin, sedation and muscle relaxants. Tetanus is a vaccine-preventable neurological disease caused by Clostridium tetani spores entering the body through wounds. It causes painful muscle
Tuberculosis, or TB, is caused by bacteria that usually affect the lungs. It can be spread through the air when someone with active TB coughs or sneezes. There are two types of TB infection - latent TB, where the bacteria remain inactive in the body, and active TB, where the bacteria are causing symptoms and can be transmitted. To prevent the spread of TB, it is important to avoid exposure to those with active infections, get tested if exposed, and begin treatment right away if diagnosed with latent TB.
We know that mesothelioma patients would rather stay local when receiving treatment,rnso we will review options for private medical centers, surgical consultants, clinical trials,rnand match you up with friendly, local physicians wherever we can.
There are two main approaches to treating trichotillomania: medication and behavioral therapy. Medication alone, such as antidepressants, has shown low success rates. The most effective treatment is behavioral therapy like habit reversal training, which teaches patients to monitor their hair pulling and replace it with healthier habits. This type of therapy has shown success rates over 90%. Alternative therapies may include hypnosis or biofeedback.
This document discusses several ethical dilemmas that can arise at the end of life. It describes situations involving conflicts between clinicians and families over appropriate care, as well as conflicts within clinical teams. It also addresses issues around withdrawing or withholding treatment, physician assisted suicide, palliative sedation, and ensuring comfort at end of life. The document emphasizes the importance of open communication, establishing goals of care based on patient values and preferences, and providing care aimed at both cure and comfort.
What has been learned from the major observationalfalcaoebarros
The document discusses 4 main lessons learned from major observational studies and clinical trials on hormonal treatments: 1) Progestagens may suppress some benefits of estrogens and slightly increase breast cancer risk with long-term use; 2) Estrogens alone did not increase breast cancer risk; 3) Metabolic effects of hormones differ by route and regimen; 4) Hormones are effective for vasomotor symptoms but not secondary cardiovascular prevention. It also discusses the need for evidence-informed practice over strictly evidence-based medicine and emphasizes balancing risks and benefits of treatments tailored to individual needs and preferences.
Our alternative 3E – Program is based on what people have actually done to survive cancer. We have learned from them and have incorporated this knowledge into our 3E program. Treating cancer with alternative strategies and without chemotherapy has become a possibility for an ever-increasing number of people.
Dr Pompa - The Missing Strategy to Stay Lean and Healthy: Not Only Missed, Bu...DwightVillos
This document discusses the hidden causes of modern health issues like autism, dementia, thyroid problems, and chronic fatigue. It argues that environmental toxins like pesticides, mercury, lead, and glyphosate are overwhelming the body and disrupting hormones. These toxins can pass from mother to baby for four generations and trigger genetic susceptibility. Weight gain and hormone resistance are linked to cellular inflammation from toxins. True detox must occur at the cellular level. A conference is promoted to discuss health centers of the future focused on real detox at the cellular level.
This document provides guidance on assessing and managing a poisoned child. It discusses the common causes of pediatric poisoning, important clinical assessments like vital signs and physical exam findings, key investigations like lab tests and toxicology screens, and general treatment approaches focusing on supportive care, decontamination, enhanced elimination, and antidotes. The toxidromes of various substance classes are also reviewed to help identify the potential toxin. A thorough history and physical exam tailored to potential exposures is emphasized for diagnosis and management of the poisoned child.
Methods of life extension currently availabelavturchin
This document provides an overview of currently available methods for life extension organized into the following categories: lifestyle changes, social life, ecology, motivation, country of residence, risk reduction, health checks, nutrition, mobility, supplements, sleep, controlling health parameters, hormone therapy, hormesis, medications, medical insurance, brain health, regeneration, cryonics, and maintaining motivation. The document outlines specific actions individuals can take within each category to potentially extend their lifespan based on current scientific research and understanding.
Similar to Glioblastoma: go for the cocktail approach! (12)
Nano-gold for Cancer Therapy chemistry investigatory projectSIVAVINAYAKPK
chemistry investigatory project
The development of nanogold-based cancer therapy could revolutionize oncology by providing a more targeted, less invasive treatment option. This project contributes to the growing body of research aimed at harnessing nanotechnology for medical applications, paving the way for future clinical trials and potential commercial applications.
Cancer remains one of the leading causes of death worldwide, prompting the need for innovative treatment methods. Nanotechnology offers promising new approaches, including the use of gold nanoparticles (nanogold) for targeted cancer therapy. Nanogold particles possess unique physical and chemical properties that make them suitable for drug delivery, imaging, and photothermal therapy.
STUDIES IN SUPPORT OF SPECIAL POPULATIONS: GERIATRICS E7shruti jagirdar
Unit 4: MRA 103T Regulatory affairs
This guideline is directed principally toward new Molecular Entities that are
likely to have significant use in the elderly, either because the disease intended
to be treated is characteristically a disease of aging ( e.g., Alzheimer's disease) or
because the population to be treated is known to include substantial numbers of
geriatric patients (e.g., hypertension).
Nutritional deficiency Disorder are problems in india.
It is very important to learn about Indian child's nutritional parameters as well the Disease related to alteration in their Nutrition.
Storyboard on Acne-Innovative Learning-M. pharm. (2nd sem.) CosmeticsMuskanShingari
Acne is a common skin condition that occurs when hair follicles become clogged with oil and dead skin cells. It typically manifests as pimples, blackheads, or whiteheads, often on the face, chest, shoulders, or back. Acne can range from mild to severe and may cause emotional distress and scarring in some cases.
**Causes:**
1. **Excess Oil Production:** Hormonal changes during adolescence or certain times in adulthood can increase sebum (oil) production, leading to clogged pores.
2. **Clogged Pores:** When dead skin cells and oil block hair follicles, bacteria (usually Propionibacterium acnes) can thrive, causing inflammation and acne lesions.
3. **Hormonal Factors:** Fluctuations in hormone levels, such as during puberty, menstrual cycles, pregnancy, or certain medical conditions, can contribute to acne.
4. **Genetics:** A family history of acne can increase the likelihood of developing the condition.
**Types of Acne:**
- **Whiteheads:** Closed plugged pores.
- **Blackheads:** Open plugged pores with a dark surface.
- **Papules:** Small red, tender bumps.
- **Pustules:** Pimples with pus at their tips.
- **Nodules:** Large, solid, painful lumps beneath the surface.
- **Cysts:** Painful, pus-filled lumps beneath the surface that can cause scarring.
**Treatment:**
Treatment depends on the severity and type of acne but may include:
- **Topical Treatments:** Such as benzoyl peroxide, salicylic acid, or retinoids to reduce bacteria and unclog pores.
- **Oral Medications:** Antibiotics or oral contraceptives for hormonal acne.
- **Procedures:** Such as chemical peels, extraction of comedones, or light therapy for more severe cases.
**Prevention and Management:**
- **Cleanse:** Regularly wash skin with a gentle cleanser.
- **Moisturize:** Use non-comedogenic moisturizers to keep skin hydrated without clogging pores.
- **Avoid Irritants:** Such as harsh cosmetics or excessive scrubbing.
- **Sun Protection:** Use sunscreen to prevent exacerbation of acne scars and inflammation.
Acne treatment can take time, and consistency in skincare routines and treatments is crucial. Consulting a dermatologist can help tailor a treatment plan that suits individual needs and reduces the risk of scarring or long-term skin damage.
Selective alpha1 blockers are Prazosin, Terazosin, Doxazosin, Tamsulosin and Silodosin majorly used to treat BPH, also hypertension, PTSD, Raynaud's phenomenon, CHF
“Environmental sanitation means the art and science of applying sanitary, biological and physical science principles and knowledge to improve and control the environment therein for the protection of the health and welfare of the public”.The overall importance of sanitation are to provide a healthy living environment for everyone, to protect the natural resources (such as surface water, groundwater, soil ), and to provide safety, security and dignity for people when they defecate or urinate .Sanitation refers to public health conditions such as drinking clean water, sewage treatment, etc. All the effective tools and actions that help in keeping the environment clean come under sanitation. Sanitation refers to public health conditions such as drinking clean water, sewage treatment. All the effective tools and actions that help in keeping the environment clean and promotes public health is the necessary in todays life.
Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdfOsvaldo Bernardo Muchanga
GASTROINTESTINAL INFECTIONS AND GASTRITIS
Osvaldo Bernardo Muchanga
Gastrointestinal Infections
GASTROINTESTINAL INFECTIONS result from the ingestion of pathogens that cause infections at the level of this tract, generally being transmitted by food, water and hands contaminated by microorganisms such as E. coli, Salmonella, Shigella, Vibrio cholerae, Campylobacter, Staphylococcus, Rotavirus among others that are generally contained in feces, thus configuring a FECAL-ORAL type of transmission.
Among the factors that lead to the occurrence of gastrointestinal infections are the hygienic and sanitary deficiencies that characterize our markets and other places where raw or cooked food is sold, poor environmental sanitation in communities, deficiencies in water treatment (or in the process of its plumbing), risky hygienic-sanitary habits (not washing hands after major and/or minor needs), among others.
These are generally consequences (signs and symptoms) resulting from gastrointestinal infections: diarrhea, vomiting, fever and malaise, among others.
The treatment consists of replacing lost liquids and electrolytes (drinking drinking water and other recommended liquids, including consumption of juicy fruits such as papayas, apples, pears, among others that contain water in their composition).
To prevent this, it is necessary to promote health education, improve the hygienic-sanitary conditions of markets and communities in general as a way of promoting, preserving and prolonging PUBLIC HEALTH.
Gastritis and Gastric Health
Gastric Health is one of the most relevant concerns in human health, with gastrointestinal infections being among the main illnesses that affect humans.
Among gastric problems, we have GASTRITIS AND GASTRIC ULCERS as the main public health problems. Gastritis and gastric ulcers normally result from inflammation and corrosion of the walls of the stomach (gastric mucosa) and are generally associated (caused) by the bacterium Helicobacter pylor, which, according to the literature, this bacterium settles on these walls (of the stomach) and starts to release urease that ends up altering the normal pH of the stomach (acid), which leads to inflammation and corrosion of the mucous membranes and consequent gastritis or ulcers, respectively.
In addition to bacterial infections, gastritis and gastric ulcers are associated with several factors, with emphasis on prolonged fasting, chemical substances including drugs, alcohol, foods with strong seasonings including chilli, which ends up causing inflammation of the stomach walls and/or corrosion. of the same, resulting in the appearance of wounds and consequent gastritis or ulcers, respectively.
Among patients with gastritis and/or ulcers, one of the dilemmas is associated with the foods to consume in order to minimize the sensation of pain and discomfort.
BBB and BCF
control the entry of compounds into the brain and
regulate brain homeostasis.
restricts access to brain cells of blood–borne compounds and
facilitates nutrients essential for normal metabolism to reach brain cells
- Video recording of this lecture in English language: https://youtu.be/RvdYsTzgQq8
- Video recording of this lecture in Arabic language: https://youtu.be/ECILGWtgZko
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
The Children are very vulnerable to get affected with respiratory disease.
In our country, the respiratory Disease conditions are consider as major cause for mortality and Morbidity in Child.
Discover the benefits of homeopathic medicine for irregular periods with our guide on 5 common remedies. Learn how these natural treatments can help regulate menstrual cycles and improve overall menstrual health.
Visit Us: https://drdeepikashomeopathy.com/service/irregular-periods-treatment/
Gene therapy can be broadly defined as the transfer of genetic material to cure a disease or at least to improve the clinical status of a patient.
One of the basic concepts of gene therapy is to transform viruses into genetic shuttles, which will deliver the gene of interest into the target cells.
Safe methods have been devised to do this, using several viral and non-viral vectors.
In the future, this technique may allow doctors to treat a disorder by inserting a gene into a patient's cells instead of using drugs or surgery.
The biggest hurdle faced by medical research in gene therapy is the availability of effective gene-carrying vectors that meet all of the following criteria:
Protection of transgene or genetic cargo from degradative action of systemic and endonucleases,
Delivery of genetic material to the target site, i.e., either cell cytoplasm or nucleus,
Low potential of triggering unwanted immune responses or genotoxicity,
Economical and feasible availability for patients .
Viruses are naturally evolved vehicles that efficiently transfer their genes into host cells.
Choice of viral vector is dependent on gene transfer efficiency, capacity to carry foreign genes, toxicity, stability, immune responses towards viral antigens and potential viral recombination.
There are a wide variety of vectors used to deliver DNA or oligo nucleotides into mammalian cells, either in vitro or in vivo.
The most common vector system based on retroviruses, adenoviruses, herpes simplex viruses, adeno associated viruses.
Congestive Heart failure is caused by low cardiac output and high sympathetic discharge. Diuretics reduce preload, ACE inhibitors lower afterload, beta blockers reduce sympathetic activity, and digitalis has inotropic effects. Newer medications target vasodilation and myosin activation to improve heart efficiency while lowering energy requirements. Combination therapy, following an assessment of cardiac function and volume status, is the most effective strategy to heart failure care.
Pharmacology of Drugs for Congestive Heart Failure
Glioblastoma: go for the cocktail approach!
1. Glioblastoma case study - age 59 - Belgian
Oct Nov Dec Jan Feb Mar Apr May
Resection (left)
Former French teacher. He created one of the biggest Belgian non-profits to help children speaking French &
English while on holiday, and having fun doing so!
In his spare time he’s a Glioblastoma patient (in left & right hemisphere)
TMZ 150mg + Radiation
Methadone
TMZ 60 mg
Cannabis oil (THC)
Immuno (virustherapy)
Boswellia + supplements
Avastin
Our message to other patients: Go for the cocktail approach!
Monotherapy cocktail
Acupuncture & Tui-na
2015 2016
2. This is only one case. We don’t have the magic recipe.
But this is what we have learned so far
Do resection if possible. And do it in a specialized hospital.
Go for a healthy lifestyle: food - sports - positive mindset. You can beat this
Join glioblastoma Facebook groups. Learn from others
Test for ALL relevant markers (MGMT, BGJ, ABT-414). Do this at the start, no time to lose, know your options
Store tumor tissue after the resection. Can be used for immune therapies
Part 1: Discovery
Part 2: Follow up treatment
Radiation: not fully convinced. I and many other patients suffered from A LOT of damage
If you take Temodar (TMZ) - do search for other medication that amplifies its effect (we used Methadon)
Go for the cocktail approach from the start. Watch out not to exclude yourself from clinical trials
3. Contact info
Our family: pjmuller@gmail.com
Immunotherapy we take (+- €30.000): Cologne - IOZK
Methadone (+-€2/month): Claudia Friessen - Ulm (best to call: +49 731 500 650 81 )
THC (€1/mg, €30/month): Medical charity only ships in Netherlands - Contact me
Resources
1h30 documentary by 21 year glioblastoma survivor
Facebook groups: [1], [2], [3] and many others
4. Other options we find interesting
Ketogenic diet
Immunotherapy: Poliovirus - Nivolumab - Ipilimumab
Perillyl alcohol (via vaporizer)
Ben Williams supplement regime
Connection to CMV / Lyme infections
Options we find less interesting
Optune / NovoTTF
pro → you ‘only’ win 3 months | con → $$$$$, life quality ↘ (invasive)