This case report from Senegal describes a giant cylindroma of the parotid gland in a 27-year-old woman. The tumor had been growing for 10 years and rapidly progressed in the last year. Due to a lack of diagnostic resources, the tumor measured 9x8 cm before surgical removal. A radical parotidectomy and neck dissection were performed, but reconstruction failed due to flap necrosis, requiring a second surgery. Histopathology found a cylindroma, which is a malignant epithelial tumor. The patient died of cerebral metastases four months later, demonstrating the challenges of diagnosing and treating large salivary gland tumors in under-resourced settings.