This document discusses the challenges and solutions in global compliance with chemical regulations, focusing on the Globally Harmonized System (GHS) for chemical labeling and safety data sheets. It highlights the need for standardization in hazard communication to improve workplace safety and compliance, particularly for chemical manufacturers as they adapt to GHS requirements. With over 65 countries adopting GHS, the paper emphasizes the importance of transitioning from traditional material safety data sheets (MSDS) to GHS-compliant safety data sheets (SDS) for effective risk management and communication.