Gentamicin - Drug Information - Taj Pharma, Gentamicin dose Taj pharmaceuticals Gentamicin interactions, Taj Pharmaceutical Gentamicin contraindications, Gentamicin price, Gentamicin Taj Pharma Gentamicin 40 mg/ml Injection SMPC- Taj Pharma . Stay connected to all updated on Gentamicin Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Metoclopramide hydrochloride 10 mg tablets smpc taj pharmaceuticalsTaj Pharma
Metoclopramide Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Metoclopramide Dosage & Rx Info | Metoclopramide Uses, Side Effects -: Indications, Side Effects, Warnings, Metoclopramide - Drug Information - Taj Pharma, Metoclopramide dose Taj pharmaceuticals Metoclopramide interactions, Taj Pharmaceutical Metoclopramide contraindications, Metoclopramide price, Metoclopramide Taj Pharma Metoclopramide Hydrochloride 10 mg tablets SMPC- Taj Pharma . Stay connected to all updated on Metoclopramide Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Ketamine Injection USP 10mg/ml, 50mg/ml, 100mg/ml Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Ketamine Dosage & Rx Info | Ketamine Uses, Side Effects Ketamine: Indications, Side Effects, Warnings, Ketamine -Drug Information –Taj Pharma, Ketamine dose Taj pharmaceuticals Ketamine interactions, Taj Pharmaceutical Ketamine contraindications, Ketamine price, Ketamine Taj Pharma Ketamine SmPC-Taj Pharma Stay connected to all updated on Ketamine Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Prednisolone 10mg tablets smpc taj pharmaceuticalsTaj Pharma
Prednisolone Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Prednisolone Dosage & Rx Info | Prednisolone Uses, Side Effects -: Indications, Side Effects, Warnings, Prednisolone - Drug Information - Taj Pharma, Prednisolone dose Taj pharmaceuticals Prednisolone interactions, Taj Pharmaceutical Prednisolone contraindications, Prednisolone price, Prednisolone Taj Pharma Prednisolone 10mg Tablets SMPC- Taj Pharma . Stay connected to all updated on Prednisolone Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Gentamicin Injection USP Taj Pharma SmPCTajPharmaQC
Gentamicin Injection USP 20mg/2ml, 80mg/2ml, 800mg/20ml Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Gentamicin Dosage & Rx Info | Gentamicin Uses, Side Effects Gentamicin: Indications, Side Effects, Warnings, Gentamicin -Drug Information –Taj Pharma, Gentamicin dose Taj pharmaceuticals Gentamicin interactions, Taj Pharmaceutical Gentamicin contraindications, Gentamicin price, Gentamicin Taj Pharma Gentamicin SmPC-Taj Pharma Stay connected to all updated on Gentamicin Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Dexamethasone 3.3 mg per ml solution for injection smpc taj pharmaceuticalsTaj Pharma
Dexamethasone - Drug Information - Taj Pharma, Dexamethasone dose Taj pharmaceuticals Dexamethasone interactions, Taj Pharmaceutical Dexamethasone contraindications, Dexamethasone price, Dexamethasone Taj Pharma Dexamethasone 3.3 mg/ml solution for injection SMPC- Taj Pharma . Stay connected to all updated on Dexamethasone Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Topotecan 1 mg concentrate for solution for infusion smpc taj pharmaceuticalsTaj Pharma
TOPOTECAN Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, TOPOTECAN Dosage & Rx Info | TOPOTECAN Uses, Side Effects -: Indications, Side Effects, Warnings, TOPOTECAN - Drug Information - Taj Pharma, TOPOTECAN dose Taj pharmaceuticals TOPOTECAN interactions, Taj Pharmaceutical TOPOTECAN contraindications, TOPOTECAN price, TOPOTECAN Taj Pharma Topotecan 1 mg/ml concentrate for solution for infusionSMPC- Taj Pharma . Stay connected to all updated on TOPOTECAN Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Metoclopramide Injection USP Taj Pharma SmPCTajPharmaQC
Metoclopramide Injection USP 10mg/2ml Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Metoclopramide Dosage & Rx Info | Metoclopramide Uses, Side Effects Metoclopramide: Indications, Side Effects, Warnings, Metoclopramide -Drug Information –Taj Pharma, Metoclopramide dose Taj pharmaceuticals Metoclopramide interactions, Taj Pharmaceutical Metoclopramide contraindications, Metoclopramide price, Metoclopramide Taj Pharma Metoclopramide SmPC-Taj Pharma Stay connected to all updated on Metoclopramide Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Tobromycin Injection USP Taj Pharma SmPCTajPharmaQC
Tobromycin Injection USP 20mg/2ml, 80mg/2ml, USP 1.2g/30ml Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Tobromycin Dosage & Rx Info | Tobromycin Uses, Side Effects Vecuronium bromide: Indications, Side Effects, Warnings, Tobromycin-Drug Information –Taj Pharma, Tobromycin dose Taj pharmaceuticals Tobromycin interactions, Taj Pharmaceutical Tobromycin contraindications, Tobromycin price, Tobromycin Taj Pharma Tobromycin SmPC-Taj Pharma Stay connected to all updated on Tobromycin Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Metoclopramide hydrochloride 10 mg tablets smpc taj pharmaceuticalsTaj Pharma
Metoclopramide Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Metoclopramide Dosage & Rx Info | Metoclopramide Uses, Side Effects -: Indications, Side Effects, Warnings, Metoclopramide - Drug Information - Taj Pharma, Metoclopramide dose Taj pharmaceuticals Metoclopramide interactions, Taj Pharmaceutical Metoclopramide contraindications, Metoclopramide price, Metoclopramide Taj Pharma Metoclopramide Hydrochloride 10 mg tablets SMPC- Taj Pharma . Stay connected to all updated on Metoclopramide Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Ketamine Injection USP 10mg/ml, 50mg/ml, 100mg/ml Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Ketamine Dosage & Rx Info | Ketamine Uses, Side Effects Ketamine: Indications, Side Effects, Warnings, Ketamine -Drug Information –Taj Pharma, Ketamine dose Taj pharmaceuticals Ketamine interactions, Taj Pharmaceutical Ketamine contraindications, Ketamine price, Ketamine Taj Pharma Ketamine SmPC-Taj Pharma Stay connected to all updated on Ketamine Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Prednisolone 10mg tablets smpc taj pharmaceuticalsTaj Pharma
Prednisolone Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Prednisolone Dosage & Rx Info | Prednisolone Uses, Side Effects -: Indications, Side Effects, Warnings, Prednisolone - Drug Information - Taj Pharma, Prednisolone dose Taj pharmaceuticals Prednisolone interactions, Taj Pharmaceutical Prednisolone contraindications, Prednisolone price, Prednisolone Taj Pharma Prednisolone 10mg Tablets SMPC- Taj Pharma . Stay connected to all updated on Prednisolone Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Gentamicin Injection USP Taj Pharma SmPCTajPharmaQC
Gentamicin Injection USP 20mg/2ml, 80mg/2ml, 800mg/20ml Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Gentamicin Dosage & Rx Info | Gentamicin Uses, Side Effects Gentamicin: Indications, Side Effects, Warnings, Gentamicin -Drug Information –Taj Pharma, Gentamicin dose Taj pharmaceuticals Gentamicin interactions, Taj Pharmaceutical Gentamicin contraindications, Gentamicin price, Gentamicin Taj Pharma Gentamicin SmPC-Taj Pharma Stay connected to all updated on Gentamicin Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Dexamethasone 3.3 mg per ml solution for injection smpc taj pharmaceuticalsTaj Pharma
Dexamethasone - Drug Information - Taj Pharma, Dexamethasone dose Taj pharmaceuticals Dexamethasone interactions, Taj Pharmaceutical Dexamethasone contraindications, Dexamethasone price, Dexamethasone Taj Pharma Dexamethasone 3.3 mg/ml solution for injection SMPC- Taj Pharma . Stay connected to all updated on Dexamethasone Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Topotecan 1 mg concentrate for solution for infusion smpc taj pharmaceuticalsTaj Pharma
TOPOTECAN Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, TOPOTECAN Dosage & Rx Info | TOPOTECAN Uses, Side Effects -: Indications, Side Effects, Warnings, TOPOTECAN - Drug Information - Taj Pharma, TOPOTECAN dose Taj pharmaceuticals TOPOTECAN interactions, Taj Pharmaceutical TOPOTECAN contraindications, TOPOTECAN price, TOPOTECAN Taj Pharma Topotecan 1 mg/ml concentrate for solution for infusionSMPC- Taj Pharma . Stay connected to all updated on TOPOTECAN Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Metoclopramide Injection USP Taj Pharma SmPCTajPharmaQC
Metoclopramide Injection USP 10mg/2ml Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Metoclopramide Dosage & Rx Info | Metoclopramide Uses, Side Effects Metoclopramide: Indications, Side Effects, Warnings, Metoclopramide -Drug Information –Taj Pharma, Metoclopramide dose Taj pharmaceuticals Metoclopramide interactions, Taj Pharmaceutical Metoclopramide contraindications, Metoclopramide price, Metoclopramide Taj Pharma Metoclopramide SmPC-Taj Pharma Stay connected to all updated on Metoclopramide Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Tobromycin Injection USP Taj Pharma SmPCTajPharmaQC
Tobromycin Injection USP 20mg/2ml, 80mg/2ml, USP 1.2g/30ml Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Tobromycin Dosage & Rx Info | Tobromycin Uses, Side Effects Vecuronium bromide: Indications, Side Effects, Warnings, Tobromycin-Drug Information –Taj Pharma, Tobromycin dose Taj pharmaceuticals Tobromycin interactions, Taj Pharmaceutical Tobromycin contraindications, Tobromycin price, Tobromycin Taj Pharma Tobromycin SmPC-Taj Pharma Stay connected to all updated on Tobromycin Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Paracetamol 10 mg per ml solution for infusion smpc taj pharmaceuticalsTaj Pharma
Paracetamol - Drug Information - Taj Pharma, Paracetamol dose Taj pharmaceuticals Paracetamol interactions, Taj Pharmaceutical Paracetamol contraindications, Paracetamol price, Paracetamol Taj Pharma Paracetamol 10 mg/ml Solution for Infusion SMPC- Taj Pharma . Stay connected to all updated on Paracetamol Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
This document provides guidelines for using ketamine to treat pain in palliative care settings. It outlines that ketamine is effective for treating opioid-resistant pain from conditions like cancer and neuropathy. The guidelines recommend starting with intravenous ketamine to quickly determine dosage and monitor side effects before potentially switching to oral administration. Dosages are provided for both intravenous and oral ketamine use, along with guidance on monitoring patients, managing side effects, and adjusting dosages based on response to treatment. Contraindications and drug interactions are also reviewed.
Fenofibrate 160 mg tablets smpc taj pharmaceuticalsTaj Pharma
Fenofibrate Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Fenofibrate Dosage & Rx Info | Fenofibrate Uses, Side Effects -: Indications, Side Effects, Warnings, Fenofibrate - Drug Information - Taj Pharma, Fenofibrate dose Taj pharmaceuticals Fenofibrate interactions, Taj Pharmaceutical Fenofibrate contraindications, Fenofibrate price, Fenofibrate Taj Pharma Fenofibrate 160 mg Tablets. SMPC- Taj Pharma . Stay connected to all updated on Fenofibrate Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Bleomycin for Injection Taj Pharma SmPCTajPharmaQC
Bleomycin for Injection 15 Units, 30 Units Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Bleomycin Dosage & Rx Info | Bleomycin Uses, Side Effects Bleomycin: Indications, Side Effects, Warnings, Bleomycin -Drug Information –Taj Pharma, Bleomycin dose Taj pharmaceuticals Bleomycin interactions, Taj Pharmaceutical Bleomycin contraindications, Bleomycin price, Bleomycin Taj Pharma Bleomycin SmPC-Taj Pharma Stay connected to all updated on Bleomycin Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SMPC.
Betamethasone 0.5 mg soluble tablets smpc taj pharmaceuticalsTaj Pharma
Betamethasone Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Betamethasone Dosage & Rx Info | Betamethasone Uses, Side Effects -: Indications, Side Effects, Warnings, Betamethasone - Drug Information - Taj Pharma, Betamethasone dose Taj pharmaceuticals Betamethasone interactions, Taj Pharmaceutical Betamethasone contraindications, Betamethasone price, Betamethasone Taj Pharma Betamethasone 500 microgram Soluble Tablets SMPC- Taj Pharma . Stay connected to all updated on Betamethasone Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Captopril Tablets SmPC Taj PharmaceuticalsTajPharmaQC
Captopril Tablets USP 25mg, 50mg, 100mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Captopril Dosage & Rx Info | Captopril Uses, Side Effects Captopril: Indications, Side Effects, Warnings, Captopril -Drug Information –Taj Pharma, Captopril dose Taj pharmaceuticals Captopril interactions, Taj Pharmaceutical Captopril contraindications, Captopril price, Captopril Taj Pharma Captopril SmPC- Taj Pharma Stay connected to all updated on Captopril Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SMPC.
Nilotinib Capsules 50mg/150mg/200mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Nilotinib Dosage & Rx Info | Nilotinib Uses, Side Effects Nilotinib: Indications, Side Effects, Warnings, Nilotinib -Drug Information –Taj Pharma, Nilotinib dose Taj pharmaceuticals Nilotinib interactions, Taj Pharmaceutical Nilotinib contraindications, Nilotinib price, Nilotinib Taj Pharma Nilotinib SmPC-Taj Pharma Stay connected to all updated on Nilotinib Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Clonazepam 500mcg tablets smpc taj pharmaceuticalsTaj Pharma
Clonazepam Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Clonazepam Dosage & Rx Info | Clonazepam Uses, Side Effects -: Indications, Side Effects, Warnings, Clonazepam - Drug Information - Taj Pharma, Clonazepam dose Taj pharmaceuticals Clonazepam interactions, Taj Pharmaceutical Clonazepam contraindications, Clonazepam price, Clonazepam Taj Pharma Clonazepam 500mcg Tablets SMPC- Taj Pharma . Stay connected to all updated on Clonazepam Taj Pharmaceuticals Taj pharmaceuticals Hyderabad
Gabapentin 300mg capsules smpc taj pharmaceuticalsTaj Pharma
Gabapentin Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Gabapentin Dosage & Rx Info | Gabapentin Uses, Side Effects -: Indications, Side Effects, Warnings, Gabapentin - Drug Information - Taj Pharma, Gabapentin dose Taj pharmaceuticals Gabapentin interactions, Taj Pharmaceutical Gabapentin contraindications, Gabapentin price, Gabapentin Taj Pharma Gabapentin 300mg capsules SMPC- Taj Pharma . Stay connected to all updated on Gabapentin Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Cisplatin for Injection Taj Pharma SmPCTajPharmaQC
Cisplatin Injection BP 10mg/10ml, 10mg/20ml, 50mg/50ml, 100mg/100ml and 200mg/200ml Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Cisplatin Dosage & Rx Info | Cisplatin Uses, Side Effects Cisplatin: Indications, Side Effects, Warnings, Cisplatin -Drug Information –Taj Pharma, Cisplatin dose Taj pharmaceuticals Cisplatin interactions, Taj Pharmaceutical Cisplatin contraindications, Cisplatin price, Cisplatin Taj Pharma Cisplatin SmPC-Taj Pharma Stay connected to all updated on Cisplatin Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SMPC.
Metformin 500mg tablets smpc taj pharmaceuticalsTaj Pharma
Metformin Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Metformin Dosage & Rx Info | Metformin Uses, Side Effects -: Indications, Side Effects, Warnings, Metformin - Drug Information - Taj Pharma, Metformin dose Taj pharmaceuticals Metformin interactions, Taj Pharmaceutical Metformin contraindications, Metformin price, Metformin Taj Pharma Metformin 500mg Tablets SMPC- Taj Pharma . Stay connected to all updated on Metformin Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
This document provides information on Paracetamol 500mg Tablets manufactured by Taj Pharmaceuticals. It describes the drug's approved uses for mild to moderate pain and fever relief, dosages for adults and children, contraindications like hypersensitivity, and warnings about potential liver damage from overdose. Side effects are typically mild. The drug's mechanism of action involves inhibiting prostaglandin synthesis in the central nervous system for its analgesic and antipyretic effects.
Paracetamol and ibuprofen 500 mg and 150 mg film coated tablets smpc taj pha...Taj Pharma
Paracetamol and Ibuprofen - Drug Information - Taj Pharma, Paracetamol and Ibuprofen dose Taj pharmaceuticals Paracetamol and Ibuprofen interactions, Taj Pharmaceutical Paracetamol and Ibuprofen contraindications, Paracetamol and Ibuprofen price, Paracetamol and Ibuprofen Taj Pharma Paracetamol and Ibuprofen 500 mg/150 mg film coated tablets SMPC- Taj Pharma . Stay connected to all updated on Paracetamol and Ibuprofen Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Trimethoprim 80mg and sulfamethoxazole 400mg tablets smpc taj pharmaceuticalsTaj Pharma
Trimethoprim and sulfamethoxazole Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Trimethoprim and sulfamethoxazole Dosage & Rx Info | Trimethoprim and sulfamethoxazole Uses, Side Effects -: Indications, Side Effects, Warnings, Trimethoprim and sulfamethoxazole - Drug Information - Taj Pharma, Trimethoprim and sulfamethoxazole dose Taj pharmaceuticals Trimethoprim and sulfamethoxazole interactions, Taj Pharmaceutical Trimethoprim and sulfamethoxazole contraindications, Trimethoprim and sulfamethoxazole price, Trimethoprim and sulfamethoxazole Taj Pharma Trimethoprim 80mg and sulfamethoxazole 400mg tablets SMPC- Taj Pharma . Stay connected to all updated on Trimethoprim and sulfamethoxazole Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Topiramate tablets are available in 15mg and 100mg strengths from Taj Pharma. Topiramate is indicated as monotherapy for partial seizures in adults and children over 6, and as adjunctive therapy for partial seizures, primary generalized tonic-clonic seizures, and Lennox-Gastaut syndrome in children and adults. It is also indicated for migraine prophylaxis in adults. Common side effects include mood disturbances, depression, and kidney stones. Dosage should be titrated slowly from low starting doses and monitored based on clinical response and tolerability. Special precautions are needed in patients with renal or hepatic impairment.
Simvastatin Tablets USP Taj Pharma SmPCTajPharmaQC
Simvastatin Tablets USP 20mg, 40mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Simvastatin Dosage & Rx Info | Simvastatin Uses, Side Effects Simvastatin: Indications, Side Effects, Warnings, Simvastatin-Drug Information –Taj Pharma, Simvastatin dose Taj pharmaceuticals Simvastatin interactions, Taj Pharmaceutical Simvastatin contraindications, Simvastatin price, Simvastatin Taj Pharma Simvastatin SmPC-Taj Pharma Stay connected to all updated on Simvastatin Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SMPC.
Part 2 - Aminoglycoside Vancomycin dosingJeff Tollison
This document provides guidance on dosing aminoglycosides and vancomycin. It discusses obtaining relevant patient information for dosing calculations including weight, height, creatinine, and infection details. It recommends using online calculators or nomograms to determine initial doses, with monitoring levels to adjust subsequent doses. For patients without labs, it suggests conservative initial loading doses until labs are available. Close monitoring is advised for elderly or renally impaired patients.
Pantoprazole Sodium for Injection Taj Pharma SmPCTajPharmaQC
Pantoprazole Sodium for Injection 40mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Pantoprazole Sodium Dosage & Rx Info | Pantoprazole Sodium Uses, Side Effects Vecuronium bromide: Indications, Side Effects, Warnings, Pantoprazole Sodium-Drug Information –Taj Pharma, Pantoprazole Sodium dose Taj pharmaceuticals Pantoprazole Sodium interactions, Taj Pharmaceutical Pantoprazole Sodium contraindications, Pantoprazole Sodium price, Pantoprazole Sodium Taj Pharma Pantoprazole Sodium SmPC-Taj Pharma Stay connected to all updated on Pantoprazole Sodium Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Gemcitabine 200mg, 1g powder for solution for infusion smpc taj pharmaceuticalsTaj Pharma
GEMCITABINE Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, GEMCITABINE Dosage & Rx Info | GEMCITABINE Uses, Side Effects -: Indications, Side Effects, Warnings, GEMCITABINE - Drug Information - Taj Pharma, GEMCITABINE dose Taj pharmaceuticals GEMCITABINE interactions, Taj Pharmaceutical GEMCITABINE contraindications, GEMCITABINE price, GEMCITABINE Taj Pharma Cancer, oncologyGemcitabine 200mg, 1g Powder for Solution for Infusion. SMPC- Taj Pharma
Deflazacort 6mg tablets smpc taj pharmaceuticalsTaj Pharma
Deflazacort Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Deflazacort Dosage & Rx Info | Deflazacort Uses, Side Effects -: Indications, Side Effects, Warnings, Deflazacort - Drug Information - Taj Pharma, Deflazacort dose Taj pharmaceuticals Deflazacort interactions, Taj Pharmaceutical Deflazacort contraindications, Deflazacort price, Deflazacort Taj Pharma Deflazacort 6mg Tablets SMPC- Taj Pharma . Stay connected to all updated on Deflazacort Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Gentamicin and the Yorkshire-Hartford RegimenKev Frost
This document provides information on gentamicin, an aminoglycoside antibiotic. It discusses gentamicin's mechanism of action, pharmacokinetics, dosing regimens including the Hartford extended interval regimen, and monitoring requirements. The Hartford regimen aims to maximize bacterial killing while minimizing toxicity by administering a once daily gentamicin dose and monitoring serum levels to determine subsequent dosing intervals.
Paracetamol 10 mg per ml solution for infusion smpc taj pharmaceuticalsTaj Pharma
Paracetamol - Drug Information - Taj Pharma, Paracetamol dose Taj pharmaceuticals Paracetamol interactions, Taj Pharmaceutical Paracetamol contraindications, Paracetamol price, Paracetamol Taj Pharma Paracetamol 10 mg/ml Solution for Infusion SMPC- Taj Pharma . Stay connected to all updated on Paracetamol Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
This document provides guidelines for using ketamine to treat pain in palliative care settings. It outlines that ketamine is effective for treating opioid-resistant pain from conditions like cancer and neuropathy. The guidelines recommend starting with intravenous ketamine to quickly determine dosage and monitor side effects before potentially switching to oral administration. Dosages are provided for both intravenous and oral ketamine use, along with guidance on monitoring patients, managing side effects, and adjusting dosages based on response to treatment. Contraindications and drug interactions are also reviewed.
Fenofibrate 160 mg tablets smpc taj pharmaceuticalsTaj Pharma
Fenofibrate Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Fenofibrate Dosage & Rx Info | Fenofibrate Uses, Side Effects -: Indications, Side Effects, Warnings, Fenofibrate - Drug Information - Taj Pharma, Fenofibrate dose Taj pharmaceuticals Fenofibrate interactions, Taj Pharmaceutical Fenofibrate contraindications, Fenofibrate price, Fenofibrate Taj Pharma Fenofibrate 160 mg Tablets. SMPC- Taj Pharma . Stay connected to all updated on Fenofibrate Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Bleomycin for Injection Taj Pharma SmPCTajPharmaQC
Bleomycin for Injection 15 Units, 30 Units Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Bleomycin Dosage & Rx Info | Bleomycin Uses, Side Effects Bleomycin: Indications, Side Effects, Warnings, Bleomycin -Drug Information –Taj Pharma, Bleomycin dose Taj pharmaceuticals Bleomycin interactions, Taj Pharmaceutical Bleomycin contraindications, Bleomycin price, Bleomycin Taj Pharma Bleomycin SmPC-Taj Pharma Stay connected to all updated on Bleomycin Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SMPC.
Betamethasone 0.5 mg soluble tablets smpc taj pharmaceuticalsTaj Pharma
Betamethasone Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Betamethasone Dosage & Rx Info | Betamethasone Uses, Side Effects -: Indications, Side Effects, Warnings, Betamethasone - Drug Information - Taj Pharma, Betamethasone dose Taj pharmaceuticals Betamethasone interactions, Taj Pharmaceutical Betamethasone contraindications, Betamethasone price, Betamethasone Taj Pharma Betamethasone 500 microgram Soluble Tablets SMPC- Taj Pharma . Stay connected to all updated on Betamethasone Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Captopril Tablets SmPC Taj PharmaceuticalsTajPharmaQC
Captopril Tablets USP 25mg, 50mg, 100mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Captopril Dosage & Rx Info | Captopril Uses, Side Effects Captopril: Indications, Side Effects, Warnings, Captopril -Drug Information –Taj Pharma, Captopril dose Taj pharmaceuticals Captopril interactions, Taj Pharmaceutical Captopril contraindications, Captopril price, Captopril Taj Pharma Captopril SmPC- Taj Pharma Stay connected to all updated on Captopril Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SMPC.
Nilotinib Capsules 50mg/150mg/200mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Nilotinib Dosage & Rx Info | Nilotinib Uses, Side Effects Nilotinib: Indications, Side Effects, Warnings, Nilotinib -Drug Information –Taj Pharma, Nilotinib dose Taj pharmaceuticals Nilotinib interactions, Taj Pharmaceutical Nilotinib contraindications, Nilotinib price, Nilotinib Taj Pharma Nilotinib SmPC-Taj Pharma Stay connected to all updated on Nilotinib Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Clonazepam 500mcg tablets smpc taj pharmaceuticalsTaj Pharma
Clonazepam Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Clonazepam Dosage & Rx Info | Clonazepam Uses, Side Effects -: Indications, Side Effects, Warnings, Clonazepam - Drug Information - Taj Pharma, Clonazepam dose Taj pharmaceuticals Clonazepam interactions, Taj Pharmaceutical Clonazepam contraindications, Clonazepam price, Clonazepam Taj Pharma Clonazepam 500mcg Tablets SMPC- Taj Pharma . Stay connected to all updated on Clonazepam Taj Pharmaceuticals Taj pharmaceuticals Hyderabad
Gabapentin 300mg capsules smpc taj pharmaceuticalsTaj Pharma
Gabapentin Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Gabapentin Dosage & Rx Info | Gabapentin Uses, Side Effects -: Indications, Side Effects, Warnings, Gabapentin - Drug Information - Taj Pharma, Gabapentin dose Taj pharmaceuticals Gabapentin interactions, Taj Pharmaceutical Gabapentin contraindications, Gabapentin price, Gabapentin Taj Pharma Gabapentin 300mg capsules SMPC- Taj Pharma . Stay connected to all updated on Gabapentin Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Cisplatin for Injection Taj Pharma SmPCTajPharmaQC
Cisplatin Injection BP 10mg/10ml, 10mg/20ml, 50mg/50ml, 100mg/100ml and 200mg/200ml Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Cisplatin Dosage & Rx Info | Cisplatin Uses, Side Effects Cisplatin: Indications, Side Effects, Warnings, Cisplatin -Drug Information –Taj Pharma, Cisplatin dose Taj pharmaceuticals Cisplatin interactions, Taj Pharmaceutical Cisplatin contraindications, Cisplatin price, Cisplatin Taj Pharma Cisplatin SmPC-Taj Pharma Stay connected to all updated on Cisplatin Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SMPC.
Metformin 500mg tablets smpc taj pharmaceuticalsTaj Pharma
Metformin Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Metformin Dosage & Rx Info | Metformin Uses, Side Effects -: Indications, Side Effects, Warnings, Metformin - Drug Information - Taj Pharma, Metformin dose Taj pharmaceuticals Metformin interactions, Taj Pharmaceutical Metformin contraindications, Metformin price, Metformin Taj Pharma Metformin 500mg Tablets SMPC- Taj Pharma . Stay connected to all updated on Metformin Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
This document provides information on Paracetamol 500mg Tablets manufactured by Taj Pharmaceuticals. It describes the drug's approved uses for mild to moderate pain and fever relief, dosages for adults and children, contraindications like hypersensitivity, and warnings about potential liver damage from overdose. Side effects are typically mild. The drug's mechanism of action involves inhibiting prostaglandin synthesis in the central nervous system for its analgesic and antipyretic effects.
Paracetamol and ibuprofen 500 mg and 150 mg film coated tablets smpc taj pha...Taj Pharma
Paracetamol and Ibuprofen - Drug Information - Taj Pharma, Paracetamol and Ibuprofen dose Taj pharmaceuticals Paracetamol and Ibuprofen interactions, Taj Pharmaceutical Paracetamol and Ibuprofen contraindications, Paracetamol and Ibuprofen price, Paracetamol and Ibuprofen Taj Pharma Paracetamol and Ibuprofen 500 mg/150 mg film coated tablets SMPC- Taj Pharma . Stay connected to all updated on Paracetamol and Ibuprofen Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Trimethoprim 80mg and sulfamethoxazole 400mg tablets smpc taj pharmaceuticalsTaj Pharma
Trimethoprim and sulfamethoxazole Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Trimethoprim and sulfamethoxazole Dosage & Rx Info | Trimethoprim and sulfamethoxazole Uses, Side Effects -: Indications, Side Effects, Warnings, Trimethoprim and sulfamethoxazole - Drug Information - Taj Pharma, Trimethoprim and sulfamethoxazole dose Taj pharmaceuticals Trimethoprim and sulfamethoxazole interactions, Taj Pharmaceutical Trimethoprim and sulfamethoxazole contraindications, Trimethoprim and sulfamethoxazole price, Trimethoprim and sulfamethoxazole Taj Pharma Trimethoprim 80mg and sulfamethoxazole 400mg tablets SMPC- Taj Pharma . Stay connected to all updated on Trimethoprim and sulfamethoxazole Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Topiramate tablets are available in 15mg and 100mg strengths from Taj Pharma. Topiramate is indicated as monotherapy for partial seizures in adults and children over 6, and as adjunctive therapy for partial seizures, primary generalized tonic-clonic seizures, and Lennox-Gastaut syndrome in children and adults. It is also indicated for migraine prophylaxis in adults. Common side effects include mood disturbances, depression, and kidney stones. Dosage should be titrated slowly from low starting doses and monitored based on clinical response and tolerability. Special precautions are needed in patients with renal or hepatic impairment.
Simvastatin Tablets USP Taj Pharma SmPCTajPharmaQC
Simvastatin Tablets USP 20mg, 40mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Simvastatin Dosage & Rx Info | Simvastatin Uses, Side Effects Simvastatin: Indications, Side Effects, Warnings, Simvastatin-Drug Information –Taj Pharma, Simvastatin dose Taj pharmaceuticals Simvastatin interactions, Taj Pharmaceutical Simvastatin contraindications, Simvastatin price, Simvastatin Taj Pharma Simvastatin SmPC-Taj Pharma Stay connected to all updated on Simvastatin Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SMPC.
Part 2 - Aminoglycoside Vancomycin dosingJeff Tollison
This document provides guidance on dosing aminoglycosides and vancomycin. It discusses obtaining relevant patient information for dosing calculations including weight, height, creatinine, and infection details. It recommends using online calculators or nomograms to determine initial doses, with monitoring levels to adjust subsequent doses. For patients without labs, it suggests conservative initial loading doses until labs are available. Close monitoring is advised for elderly or renally impaired patients.
Pantoprazole Sodium for Injection Taj Pharma SmPCTajPharmaQC
Pantoprazole Sodium for Injection 40mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Pantoprazole Sodium Dosage & Rx Info | Pantoprazole Sodium Uses, Side Effects Vecuronium bromide: Indications, Side Effects, Warnings, Pantoprazole Sodium-Drug Information –Taj Pharma, Pantoprazole Sodium dose Taj pharmaceuticals Pantoprazole Sodium interactions, Taj Pharmaceutical Pantoprazole Sodium contraindications, Pantoprazole Sodium price, Pantoprazole Sodium Taj Pharma Pantoprazole Sodium SmPC-Taj Pharma Stay connected to all updated on Pantoprazole Sodium Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Gemcitabine 200mg, 1g powder for solution for infusion smpc taj pharmaceuticalsTaj Pharma
GEMCITABINE Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, GEMCITABINE Dosage & Rx Info | GEMCITABINE Uses, Side Effects -: Indications, Side Effects, Warnings, GEMCITABINE - Drug Information - Taj Pharma, GEMCITABINE dose Taj pharmaceuticals GEMCITABINE interactions, Taj Pharmaceutical GEMCITABINE contraindications, GEMCITABINE price, GEMCITABINE Taj Pharma Cancer, oncologyGemcitabine 200mg, 1g Powder for Solution for Infusion. SMPC- Taj Pharma
Deflazacort 6mg tablets smpc taj pharmaceuticalsTaj Pharma
Deflazacort Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Deflazacort Dosage & Rx Info | Deflazacort Uses, Side Effects -: Indications, Side Effects, Warnings, Deflazacort - Drug Information - Taj Pharma, Deflazacort dose Taj pharmaceuticals Deflazacort interactions, Taj Pharmaceutical Deflazacort contraindications, Deflazacort price, Deflazacort Taj Pharma Deflazacort 6mg Tablets SMPC- Taj Pharma . Stay connected to all updated on Deflazacort Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Gentamicin and the Yorkshire-Hartford RegimenKev Frost
This document provides information on gentamicin, an aminoglycoside antibiotic. It discusses gentamicin's mechanism of action, pharmacokinetics, dosing regimens including the Hartford extended interval regimen, and monitoring requirements. The Hartford regimen aims to maximize bacterial killing while minimizing toxicity by administering a once daily gentamicin dose and monitoring serum levels to determine subsequent dosing intervals.
Micafungin for Injection Taj Pharma SmPCTajPharmaQC
Micafungin for Injection 50mg, 100mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Micafungin Dosage & Rx Info | Micafungin Uses, Side Effects Micafungin: Indications, Side Effects, Warnings, Micafungin -Drug Information –Taj Pharma, Micafungin dose Taj pharmaceuticals Micafungin interactions, Taj Pharmaceutical Micafungin contraindications, Micafungin price, Micafungin Taj Pharma Micafungin SmPC-Taj Pharma Stay connected to all updated on Micafungin Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
This document summarizes guidelines for gentamicin use and monitoring. It describes gentamicin as a aminoglycoside antibiotic used for gram-negative infections. Once daily dosing is now preferred over multiple daily doses for better efficacy and reduced toxicity. Therapeutic drug monitoring is important given gentamicin's narrow therapeutic index, with target trough levels below 2 mg/L for once daily dosing. Dose adjustments may be needed based on gentamicin levels and renal function to ensure therapeutic levels are achieved safely.
Gemcitabine for Injection USP Taj Pharma SmPCTajPharmaQC
Gemcitabine for Injection USP 200mg, 1000mg Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Gemcitabine Dosage & Rx Info | Gemcitabine Uses, Side Effects Gemcitabine: Indications, Side Effects, Warnings, Gemcitabine -Drug Information –Taj Pharma, Gemcitabine dose Taj pharmaceuticals Gemcitabine interactions, Taj Pharmaceutical Gemcitabine contraindications, Gemcitabine price, Gemcitabine Taj Pharma Gemcitabine SmPC-Taj Pharma Stay connected to all updated on Gemcitabine Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SMPC.
Imatinib, 400mg, 100mg, film coated tablets smpc- taj pharmaceuticalsTaj Pharma
IMATINIB Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, IMATINIB Dosage & Rx Info | IMATINIB Uses, Side Effects -: Indications, Side Effects, Warnings, IMATINIB - Drug Information - Taj Pharma, IMATINIB dose Taj pharmaceuticals IMATINIB interactions, Taj Pharmaceutical IMATINIB contraindications, IMATINIB price, IMATINIB Taj Pharma Cancer, oncologyImatinib, 400mg, 100mg, film-coated tablets. SMPC- Taj Pharma . Stay connected to all updated on IMATINIB Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Amitriptyline 25mg film coated tablets smpc- taj pharmaceuticalsTaj Pharma
Amitriptyline Dosage & Rx Info | Amitriptyline Uses, Side Effects -: Indications, Side Effects, Warnings, Amitriptyline - Drug Information - Taj Pharma, Amitriptyline dose Taj pharmaceuticals Amitriptyline interactions, Taj Pharmaceutical Amitriptyline contraindications, Amitriptyline price, Amitriptyline Taj Pharma Amitriptyline 25mg Film-Coated Tablets SMPC- Taj Pharma . Stay connected to all updated on Amitriptyline Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Escitalopram 10 mg film coated tablets smpc- taj pharmaceuticalsTaj Pharma
This document is the summary of product characteristics for Escitalopram 10 mg film-coated tablets produced by Taj Pharmaceuticals. It provides information on the therapeutic uses, posology, contraindications, warnings/precautions, interactions, and adverse effects of the drug. Escitalopram is indicated for the treatment of major depressive disorder, panic disorder, social anxiety disorder, generalized anxiety disorder, and obsessive-compulsive disorder. The recommended starting dose is 10 mg daily, which can be increased to a maximum of 20 mg based on individual patient response and tolerability. Cautions are advised regarding risk of suicide, seizures, QT prolongation and interactions with other serotonergic drugs.
I am professionally pharmacist. These slides for clinical subject. Especially for pharmacy department students. I hope these students get more benefits about it.
Ondansetron 4 mg film coated tablets smpc- taj pharmaceuticalsTaj Pharma
This document provides information on the drug Ondansetron 4 mg film-coated tablets, produced by Taj Pharmaceuticals, including its uses, dosage, side effects and interactions. It is indicated for managing nausea and vomiting from chemotherapy and radiotherapy as well as preventing postoperative nausea and vomiting in adults and children. The dosage varies depending on the condition being treated, age of the patient, and other factors. Precautions are outlined for patients with hepatic or renal impairment, QT prolongation issues, or who are taking other serotonergic drugs.
Imatinib 100 mg capsules smpc taj pharmaceuticalsTaj Pharma
IMATINIB Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, IMATINIB Dosage & Rx Info | IMATINIB Uses, Side Effects -: Indications, Side Effects, Warnings, IMATINIB - Drug Information - Taj Pharma, IMATINIB dose Taj pharmaceuticals IMATINIB interactions, Taj Pharmaceutical IMATINIB contraindications, IMATINIB price, IMATINIB Taj Pharma Cancer, oncologyImatinib 100 mg capsules. SMPC- Taj Pharma . Stay connected to all updated on IMATINIB Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Ranitidine 150mg film coated tablets smpc- taj pharmaceuticalsTaj Pharma
Ranitidine Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Ranitidine Dosage & Rx Info | Ranitidine Uses, Side Effects -: Indications, Side Effects, Warnings, Ranitidine - Drug Information - Taj Pharma, Ranitidine dose Taj pharmaceuticals Ranitidine interactions, Taj Pharmaceutical Ranitidine contraindications, Ranitidine price, Ranitidine Taj Pharma Ranitidine 150mg Film-coated TabletsSMPC- Taj Pharma . Stay connected to all updated on Ranitidine Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Gabapentin is an anticonvulsant used to treat partial seizures in adults and children over 12 years old. It is also used to treat postherpetic neuralgia and pain associated with diabetic neuropathy. Common side effects include somnolence, dizziness, and fatigue. Special populations like those with renal impairment require dosage adjustments. Abrupt withdrawal may cause increased seizure frequency so gabapentin should be tapered off slowly over at least a week.
Imatinib Capsules 100mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Imatinib Dosage & Rx Info | Imatinib Uses, Side Effects Imatinib: Indications, Side Effects, Warnings, Imatinib -Drug Information –Taj Pharma, Imatinib dose Taj pharmaceuticals Imatinib interactions, Taj Pharmaceutical Imatinib contraindications, Imatinib price, Imatinib Taj Pharma Imatinib SmPC-Taj Pharma Stay connected to all updated on Imatinib Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SMPC.
This document provides information on Escitalopram 5mg, 10mg and 20mg tablets manufactured by Taj Pharma, including uses, dosage, side effects and interactions. Escitalopram is indicated for major depressive disorder, panic disorder, social anxiety disorder, generalized anxiety disorder and obsessive-compulsive disorder. It should be administered at 5-20mg daily depending on the condition and individual patient response. Special warnings are provided for pediatric use, risk of suicide and serotonin syndrome when taken with other serotonergic drugs.
This document discusses therapeutic drug monitoring (TDM) and provides examples of aminoglycosides (gentamicin and vancomycin), phenytoin, and digoxin. It defines TDM as measuring specific drug concentrations to maintain constant levels. TDM is indicated to monitor compliance, individualize therapy, diagnose under treatment, avoid toxicity, and detect drug interactions. Drugs suitable for TDM have a narrow therapeutic index, pharmacokinetic variability, a relationship between concentrations and effects, and available assays. The document provides dosing and interpretation guidelines for each drug's TDM.
This document provides guidelines for dosing adjustments of various medications in patients with renal impairment. Key points discussed include:
- Dosages of renally eliminated drugs should be adjusted based on a patient's creatinine clearance or GFR. Initial doses may need to be reduced or dosing intervals lengthened.
- Herbal medicines and over-the-counter drugs should be assessed in patients with kidney disease to avoid nephrotoxic agents.
- Many antihypertensives, analgesics, antibiotics, statins and other commonly prescribed medications require dosage adjustments with impaired renal function.
- The Cockcroft-Gault and MDRD equations can estimate creatinine clearance and GFR to
This document provides information on Dobutamine Injection 5mg/ml and 12.5mg/ml from Taj Pharma, including its uses, dosage, administration, and potential side effects. It is indicated for patients requiring positive inotropic support for cardiac decompensation or cardiogenic/septic shock. The dosage varies depending on the patient's condition and response, and must be individually adjusted. Precautions are mentioned regarding patients with severe coronary heart disease or arrhythmia risk.
Dexamethasone 4 mg tablets smpc taj pharmaceuticalsTaj Pharma
Dexamethasone Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Dexamethasone Dosage & Rx Info | Dexamethasone Uses, Side Effects -: Indications, Side Effects, Warnings, Dexamethasone - Drug Information - Taj Pharma, Dexamethasone dose Taj pharmaceuticals Dexamethasone interactions, Taj Pharmaceutical Dexamethasone contraindications, Dexamethasone price, Dexamethasone Taj Pharma Dexamethasone 4 mg tablets SMPC- Taj Pharma . Stay connected to all updated on Dexamethasone Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Similar to Gentamicin 40 mg per ml injection smpc taj pharmaceuticals (20)
Zolpiderm tartrate 5mg and 10mg tablets pil, taj pharmaceuticals.Taj Pharma
This document is a patient information leaflet for Zolpidem Tartrate 5mg and 10mg tablets produced by Taj Pharmaceuticals. It provides information on:
- What zolpidem is and what it is used for, which is the short-term treatment of insomnia.
- Contraindications and warnings for its use, including not taking it if you have breathing problems or a history of substance abuse.
- How to take zolpidem, including only taking it at bedtime for 2-4 weeks as prescribed by your doctor.
- Possible side effects and drug interactions to be aware of when taking zolpidem with other medications.
Zolpidem tartrate 5 mg tablets smpc taj pharmaceuticalsTaj Pharma
Zolpidem Tartrate - Drug Information - Taj Pharma, Zolpidem Tartrate dose Taj pharmaceuticals Zolpidem Tartrate interactions, Taj Pharmaceutical Zolpidem Tartrate contraindications, Zolpidem Tartrate price, Zolpidem Tartrate Taj Pharma Zolpidem Tartrate 5 mg Tablets SMPC- Taj Pharma . Stay connected to all updated on Zolpidem Tartrate Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Zinc 25 mg hard capsules smpc taj pharmaceuticalsTaj Pharma
Zinc - Drug Information - Taj Pharma, Zinc dose Taj pharmaceuticals Zinc interactions, Taj Pharmaceutical Zinc contraindications, Zinc price, Zinc Taj Pharma Zinc 25 mg hard capsules SMPC- Taj Pharma . Stay connected to all updated on Zinc Taj Pharmaceuticals Taj pharmaceuticals Hyderabad
Trihexyphenidyl 5mg tablets smpc taj pharmaceuticalsTaj Pharma
Trihexyphenidyl - Drug Information - Taj Pharma, Trihexyphenidyl dose Taj pharmaceuticals Trihexyphenidyl interactions, Taj Pharmaceutical Trihexyphenidyl contraindications, Trihexyphenidyl price, Trihexyphenidyl Taj Pharma Trihexyphenidyl Tablets 5mg SMPC- Taj Pharma . Stay connected to all updated on Trihexyphenidyl Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Tramadol 50mg per ml solution for injection or infusion smpc taj pharmaceuti...Taj Pharma
Tramadol - Drug Information - Taj Pharma, Tramadol dose Taj pharmaceuticals Tramadol interactions, Taj Pharmaceutical Tramadol contraindications, Tramadol price, Tramadol Taj Pharma Tramadol 50mg/ml Solution for Injection or Infusion SMPC- Taj Pharma . Stay connected to all updated on Tramadol Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Tetracycline hydrochloride 250mg tablets smpc taj pharmaceuticalsTaj Pharma
Tetracycline hydrochloride - Drug Information - Taj Pharma, Tetracycline hydrochloride dose Taj pharmaceuticals Tetracycline hydrochloride interactions, Taj Pharmaceutical Tetracycline hydrochloride contraindications, Tetracycline hydrochloride price, Tetracycline hydrochloride Taj Pharma Tetracycline hydrochloride 250mg TabletsSMPC- Taj Pharma . Stay connected to all updated on Tetracycline hydrochloride Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Tetracycline 250mg tablets pil taj pharmaceuticalsTaj Pharma
Tetracycline - Drug Information - Taj Pharma, Tetracycline dose Taj pharmaceuticals Tetracycline interactions, Taj Pharmaceutical Tetracycline contraindications, Tetracycline price, Tetracycline , Taj Pharma Tetracycline tablets 250mg PIL- Taj Pharma . Stay connected to all updated on Tetracycline Taj Pharmaceuticals Taj pharmaceuticals Hyderabad. Patient Information Leaflets, PIL.
Tadalafil 20 mg film coated tablets smpc- taj pharmaceuticalsTaj Pharma
Drug Information - Taj Pharma, Tadalafil dose Taj pharmaceuticals Tadalafil interactions, Taj Pharmaceutical Tadalafil contraindications, Tadalafil price, Tadalafil Taj Pharma Tadalafil 20 mg film-coated tablets SMPC- Taj Pharma . Stay connected to all updated on Tadalafil Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Tadalafil 10 mg film coated tablets pil, taj pharmaceuticals.Taj Pharma
Drug Information - Taj Pharma, Tadalafil dose Taj pharmaceuticals Tadalafil interactions, Taj Pharmaceutical Tadalafil contraindications, Tadalafil price, Tadalafil Taj Pharma Tadalafil 20 mg film-coated tablets PIL- Taj Pharma . Stay connected to all updated on Tadalafil Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Sodium feredetate 190mg per 5ml oral solution smpc taj pharmaceuticalsTaj Pharma
Sodium Feredetate - Drug Information - Taj Pharma, Sodium Feredetate dose Taj pharmaceuticals Sodium Feredetate interactions, Taj Pharmaceutical Sodium Feredetate contraindications, Sodium Feredetate price, Sodium Feredetate Taj Pharma Sodium Feredetate 190mg/5ml Oral Solution SMPC- Taj Pharma . Stay connected to all updated on Sodium Feredetate Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Quinine sulfate 200mg tablets smpc taj pharmaceuticalsTaj Pharma
QUININE SULFATE - Drug Information - Taj Pharma, QUININE SULFATE dose Taj pharmaceuticals QUININE SULFATE interactions, Taj Pharmaceutical QUININE SULFATE contraindications, QUININE SULFATE price, QUININE SULFATE Taj Pharma QUININE SULFATE TABLETS 200mg SMPC- Taj Pharma . Stay connected to all updated on QUININE SULFATE Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Pyrimethamine 25 mg tablets smpc taj pharmaceuticalsTaj Pharma
Pyrimethamine - Drug Information - Taj Pharma, Pyrimethamine dose Taj pharmaceuticals Pyrimethamine interactions, Taj Pharmaceutical Pyrimethamine contraindications, Pyrimethamine price, Pyrimethamine Taj Pharma Pyrimethamine 25 mg Tablets SMPC- Taj Pharma . Stay connected to all updated on Pyrimethamine Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Prednisolone acetate 1% eye drops suspension smpc taj pharmaceuticalsTaj Pharma
Prednisolone acetate - Drug Information - Taj Pharma, Prednisolone acetate dose Taj pharmaceuticals Prednisolone acetate interactions, Taj Pharmaceutical Prednisolone acetate contraindications, Prednisolone acetate price, Prednisolone acetate Taj Pharma Prednisolone acetate 1% w/v, Eye Drops SuspensionSMPC- Taj Pharma . Stay connected to all updated on Prednisolone acetate Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Piperaquine tetraphosphate 320 mg and dihydroartemisinin 40 mg film coated ta...Taj Pharma
Drug Information - Taj Pharma, dose Taj interactions, Taj Pharmaceutical Piperaquine tetraphosphate and dihydroartemisinin contraindications Taj Pharma Piperaquine tetraphosphate 320 mg and dihydroartemisinin 40 mg film coated Tablets SMPC- Taj Pharma . Stay connected to all updated on Piperaquine tetraphosphate and dihydroartemisinin Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Paracetamol 10mg per ml solution for infusion pil, taj pharmaceuticals.Taj Pharma
Paracetamol - Drug Information - Taj Pharma, Paracetamol dose Taj pharmaceuticals Paracetamol interactions, Taj Pharmaceutical Paracetamol contraindications, Paracetamol price, Paracetamol , Taj Pharma Paracetamol 10mg/ml Solution for Infusion PIL- Taj Pharma . Stay connected to all updated on Paracetamol Taj Pharmaceuticals Taj pharmaceuticals Hyderabad. Patient Information Leaflets, PIL.
Oxytetracycline 250mg tablets smpc taj pharmaceuticalsTaj Pharma
OXYTETRACYCLINE - Drug Information - Taj Pharma, OXYTETRACYCLINE dose Taj pharmaceuticals OXYTETRACYCLINE interactions, Taj Pharmaceutical OXYTETRACYCLINE contraindications, OXYTETRACYCLINE price, OXYTETRACYCLINE Taj Pharma OXYTETRACYCLINE 250MG TABLETS SMPC- Taj Pharma . Stay connected to all updated on OXYTETRACYCLINE Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Omeprazole 20mg gastro resistant capsules smpc taj pharmaceuticalsTaj Pharma
Omeprazole - Drug Information - Taj Pharma, Omeprazole dose Taj pharmaceuticals Omeprazole interactions, Taj Pharmaceutical Omeprazole contraindications, Omeprazole price, Omeprazole Taj Pharma Omeprazole 20mg Gastro-resistant Capsules SMPC- Taj Pharma . Stay connected to all updated on Omeprazole Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Norfloxacin 400 mg film coated tablet smpc- taj pharmaceuticals (autosaved)Taj Pharma
Norfloxacin - Drug Information - Taj Pharma, Norfloxacin dose Taj pharmaceuticals Norfloxacin interactions, Taj Pharmaceutical Norfloxacin contraindications, Norfloxacin price, Norfloxacin Taj Pharma Norfloxacin 400 mg film-coated tablet SMPC- Taj Pharma . Stay connected to all updated on Norfloxacin Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Metronidazole benzoate 200mg per 5ml oral suspension smpc taj pharmaceuticalsTaj Pharma
Metronidazole benzoate - Drug Information - Taj Pharma, Metronidazole benzoate dose Taj pharmaceuticals Metronidazole benzoate interactions, Taj Pharmaceutical Metronidazole benzoate contraindications, Metronidazole benzoate price, Metronidazole benzoate Taj Pharma Metronidazole benzoate 200mg/5ml Oral Suspension SMPC- Taj Pharma . Stay connected to all updated on Metronidazole benzoate Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Lamivudine 100 mg film coated tablets smpc- taj pharmaceuticalsTaj Pharma
Lamivudine - Drug Information - Taj Pharma, Lamivudine dose Taj pharmaceuticals Lamivudine interactions, Taj Pharmaceutical Lamivudine contraindications, Lamivudine price, Lamivudine Taj Pharma Lamivudine 100 mg Film-coated Tablets SMPC- Taj Pharma . Stay connected to all updated on Lamivudine Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Adhd Medication Shortage Uk - trinexpharmacy.comreignlana06
The UK is currently facing a Adhd Medication Shortage Uk, which has left many patients and their families grappling with uncertainty and frustration. ADHD, or Attention Deficit Hyperactivity Disorder, is a chronic condition that requires consistent medication to manage effectively. This shortage has highlighted the critical role these medications play in the daily lives of those affected by ADHD. Contact : +1 (747) 209 – 3649 E-mail : sales@trinexpharmacy.com
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
Promoting Wellbeing - Applied Social Psychology - Psychology SuperNotesPsychoTech Services
A proprietary approach developed by bringing together the best of learning theories from Psychology, design principles from the world of visualization, and pedagogical methods from over a decade of training experience, that enables you to: Learn better, faster!
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptxHolistified Wellness
We’re talking about Vedic Meditation, a form of meditation that has been around for at least 5,000 years. Back then, the people who lived in the Indus Valley, now known as India and Pakistan, practised meditation as a fundamental part of daily life. This knowledge that has given us yoga and Ayurveda, was known as Veda, hence the name Vedic. And though there are some written records, the practice has been passed down verbally from generation to generation.
ABDOMINAL TRAUMA in pediatrics part one.drhasanrajab
Abdominal trauma in pediatrics refers to injuries or damage to the abdominal organs in children. It can occur due to various causes such as falls, motor vehicle accidents, sports-related injuries, and physical abuse. Children are more vulnerable to abdominal trauma due to their unique anatomical and physiological characteristics. Signs and symptoms include abdominal pain, tenderness, distension, vomiting, and signs of shock. Diagnosis involves physical examination, imaging studies, and laboratory tests. Management depends on the severity and may involve conservative treatment or surgical intervention. Prevention is crucial in reducing the incidence of abdominal trauma in children.
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Osteoporosis - Definition , Evaluation and Management .pdfJim Jacob Roy
Osteoporosis is an increasing cause of morbidity among the elderly.
In this document , a brief outline of osteoporosis is given , including the risk factors of osteoporosis fractures , the indications for testing bone mineral density and the management of osteoporosis
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...
Gentamicin 40 mg per ml injection smpc taj pharmaceuticals
1. Gentamicin 40 mg/ml Injection SMPC, Taj Phar maceuticals
Gentamicin Taj Phar ma : Uses, Side Effects, Interactions, Pictures, Warnings, Gentamicin Dosage & Rx Info | Gentamicin Uses, Side Effects -: Indications, Side Effects, Warnings, Gentamicin - Drug Information - Taj Phar ma, Gentamicin dose Taj pharmac euticals Gentamicin interactions, Taj Pharmaceutical Gentamicin contraindications, Gentamicin price, Gentamicin Taj Phar ma Gentamicin 40 mg/ml Injection SMPC- Taj Phar ma . Stay connected to all updated on Gentamicin Taj Phar maceuticals Taj pharmaceuticals Hyderabad.
RX
GENTAMICIN
INJECTION
40MG/ML
1.NAME OF THE MEDICINAL PRODUCT
Gentamicin 40 mg/ml Injection.
2. QUALITATIVE AND QUANTITATIVE
COMPOSITION
1 ml of solution for injection contains 40 mg of
gentamicin (as sulphate)
1 vial of 2 ml solution for injection contains 80
mg of gentamicin (as sulphate)
For excipients, see 6.1
3. PHARMACEUTICAL FORM
Solution for injection.
Vials containing a clear colourless solution.
4. CLINICAL PARTICULARS
4.1 Therapeutic indications
Gentamicin is bactericidal and is active against
many strains of Gram-positive and Gram-
negative pathogens including species
of Escherichia, Enterobacter, Klebsiella,
Salmonella, Serratia, Shigella, Staphylococcus
aureus, some Proteus and against Pseudomonas
aeruginosa. Gentamicin is often effective
against strains of these organisms which are
resistant to other antibiotics such as
streptomycin, kanamycin and neomycin.
Gentamicin is effective against penicillin-
resistant Staphylococci, but rarely effective
against Streptococci.
Gentamicin is indicated in the treatment of the
following infections when caused by susceptible
organisms.
Consideration should be given to official local
guidance on the appropriate use of antibacterial
agents
Severe Gram-Negative Infections:
Upper and lower urinary tract infections
Burn and wound infections
Septicaemia, Bacteraemia
Abscesses
Subacute Bacterial Endocarditis
Respiratory Tract infections
(Bronchopneumonia)
Neonatal infections
Gynaecological infections
Gram-Positive Infections:
Bacteraemia
Abscesses
Accidental and operative trauma
Burns and serious skin lesions.
4.2 Posology and method of administration
Gentamicin is normally given by the
intramuscular route, but can be given
intravenously when intramuscular administration
is not feasible.
Gentamicin is normally given by the
intramuscular route, but can be given
intravenously when intramuscular administration
is not feasible, e.g. in shocked or severely
burned patients. When given intravenously, the
prescribed dose should be administered slowly
over no less than 3 minutes directly into a vein
or into the rubber tubing of a giving set. Rapid,
direct intravenous administration may give rise,
initially, to potentially neurotoxic concentrations
and it is essential that the prescribed dose is
administered over the recommended period of
time. Alternatively the prescribed dose should be
dissolved in up to 100 ml of normal saline or 5%
glucose in water, but not solutions containing
bicarbonate (see Incompatibilities P6B, 7h), and
the solution infused over no longer than 20
minutes.
The same dosage schedule is recommended for
intramuscular and intravenous dosing. Dosage is
related to the severity of infection, the age of the
patient and the patient's renal function.
2. Gentamicin 40 mg/ml Injection SMPC, Taj Phar maceuticals
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The daily dose recommended in children,
adolescents and adults with normal renal
function, is 3-6 mg/kg body weight per day as 1
(preferred) up to 2 single doses.
The daily dose in infants after the first month of
life is 4.5-7.5 mg/kg body weight per day as 1
(preferred) up to 2 single doses.
The daily dose in newborns is 4-7 mg/kg body
weight per day. Due to the longer half-life,
newborns are given the required daily dose in 1
single dose.
In impaired renal function, the recommended
daily dose has to be decreased and adjusted to
the renal function.
Doses in Patients with Impaired Renal
Function:
Dosage is adjusted for patients with renal
impairment to minimise the risk of toxicity. The
first dose should be as normal - after this, doses
should be given less frequently, the interval
being determined by results of renal function
tests as below:
Renal Function Tests:
Blood Urea
(mg/100 ml) (mmol/l)
Creatinine
Clearance
(GFR)
(ml/min)
Dose and
frequency of
administration
<40
40-100
100-200
>200
Twice weekly
intermittent
haemodialysis
6-7
6-17
17-34
>34
>70
30-70
10-30
5-10
<5
80 mg* 8-
hourly
80 mg* 12-
hourly
80 mg* daily
80 mg* every
48 hours
80 mg* after
dialysis
*60 mg if body weight <60 kg. Frequency of
dosage in hours may also be approximated as
serum creatinine (mg%) x eight or in SI units, as
serum creatinine (µmol/l) divided by 11. If these
dosage guides are used, peak serum levels must
be measured. Peak levels of gentamicin occur
approximately one hour after intra muscular
injection and intravenous injection. Trough
levels are measured just prior to the next
injection. Assay of peak serum levels gives
confirmation of adequacy of dosage and also
serves to detect levels above 10 mg/l, at which
the possibility of ototoxicity should be
considered. One hour concentrations of
gentamicin should not exceed 10 mg/l (but
should reach 4 mg/l), while the pre-dose trough
concentration should be less than 2 mg/l.
The recommended dose and precautions for
intramuscular and intravenous administration are
identical. Gentamicin when given intravenously
should be injected directly into a vein or into the
drip set tubing over no less than three minutes. If
administered by infusion, this should be over no
longer than 20 minutes and in no greater volume
of fluid than 100 ml.
Monitoring advice:
Serum concentration monitoring of gentamicin
is recommended, especially in elderly, in
newborns and in patients with impaired renal
function. Samples are taken at the end of a
dosing interval (trough level). Trough levels
should not exceed 2 µg/ml administering
gentamicin twice daily and 1 µg/ml for a once
daily dose. Please refer to section 4.4.
4.3 Contraindications
Patients being treated with gentamicin should be
under close clinical observation because of its
potential toxicity.
Hypersensitivity to gentamicin, any other
ingredient or other aminoglycosides.
Myasthenia gravis.
Gentamicin should be used with caution in
premature infants because of their renal
immaturity, in elderly people and generally in
patients with impaired renal function. Diabetes,
auditory vestibular dysfunctions, otitis media, a
history of otitis media, previous use of ototoxic
drugs and a genetically determined high
sensitivity to aminoglycoside induced
ototoxicity, are other main factors which may
pre-dispose the patient to toxicity.
4.4 Special Warnings and precautions for use
Patients being treated with gentamicin should be
under close clinical observation because of its
potential toxicity.
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As with other aminoglycosides toxicity is related
to serum concentration. At serum levels more
than 10 micrograms/ml the vestibular
mechanism may be affected. Toxicity can be
minimised by monitoring serum concentrations
and it is advisable to check serum levels to
confirm that peak levels (one hour) do not
exceed 10 micrograms/ml and that trough levels
(one hour before next injection) do not exceed 2
micrograms/ml when administering Gentamicin
twice daily and 1µg/ml for a once daily dose.
Evidence of toxicity requires adjustment of
dosage or withdrawal of the drug.
As there is some evidence that the risk of both
ototoxicity and nephrotoxicity is related to the
level of total exposure, duration of therapy
should be the shortest possible compatible with
clinical recovery.
In some patients with impaired renal function,
there has been a transient rise in blood- urea-
nitrogen, which has usually reverted to normal
during or following cessation of therapy. It is
important to adjust the frequency of dosage
according to the degree of renal function.
Gentamicin should be used with care in
conditions characterised by muscular weakness.
In cases of significant obesity gentamicin serum
concentrations should be closely monitored and
a reduction in dose should be considered.
Concurrent use of other neurotoxic and/or
nephrotoxic drugs can increase the possibility of
gentamicin toxicity. Co-administration with the
following agents should be avoided:
Neuromuscular blocking agents such as
succinylcholine and tubocurarine.
Other potentially nephrotoxic or ototoxic drugs
such as cephalosporins and methicillin.
Potent diuretics such as ethacrynic acid and
furosemide.
Other aminoglycosides.
To avoid adverse events, continuous monitoring
(before, during and after) of renal function
(serum creatinin, creatinin clearance), control of
function of vestibule and cochlea as well as
hepatic and laboratory parameters is
recommended.
Sulphites can cause allergic-type reactions
including anaphylactic symptoms and
bronchospasm in susceptible people, especially
those with a history of asthma or allergy.
The vial stopper contains dry natural rubber (a
derivative of latex), which may cause allergic
reactions.
4.5 Interaction with other medicinal products
and other forms of interaction
(i) Antibacterials: increased risk of
nephrotoxicity with cephalosporins notably
cephalothin.
(ii) Gentamicin has been known to potentiate
anticoagulants such as warfarin and
phenindione.
(iii) Antifungals: increased risk of
nephrotoxicity with amphotericin B.
(iv) Cholinergics: antagonism of effect
of neostigmine and pyridostigmine.
(v) Cyclosporin, cisplatin: increased risk of
nephrotoxicity.
(vi) Cytotoxics: increased risk of nephrotoxicity
and possible risk of ototoxicity with cisplatin.
(vii) Diuretics: increased risk of ototoxicity
with loop diuretics.
(viii) Muscle relaxants: effect of non-
depolarising muscle relaxants such
as tubocurarine enhanced. Neuromuscular
blockade and respiratory paralysis have been
reported from administration of aminoglycosides
to patients who have received curare-type
muscle relaxants during anesthesia.
(ix) Indomethacin possibly increases plasma
concentrations of gentamicin in neonates.
(x) Concurrent use of bisphosphonates may
increase the risk of hypocalcaemia.
(xi) Concurrent use of the Botulinum Toxin and
gentamicin may increase the risk of toxicity due
to enhanced neuromuscular block.
4.6 Fertility, Pregnancy and lactation
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Use in Pregnancy:
Although no teratogenic effects have been
observed, gentamicin is known to cross the
placenta. Ototoxicity in the foetus is also a
potential hazard. The benefits should, therefore,
be weighed against such hazards to the foetus
before using gentamicin during pregnancy.
Use in Lactation:
Small amounts of gentamicin have been reported
in breast milk. Because of the potential for
serious adverse reactions to an aminoglycoside
in nursing infants, a decision should be made
whether to discontinue nursing or the drug,
taking into account the importance of the drug to
the woman. In the absence of gastro-intestinal
inflammation, the amount of gentamicin
ingested from the milk is unlikely to result in
significant blood levels in breast-fed infants.
4.7 Effects on ability to drive and use
machines
Not applicable.
4.8 Undesirable Effects
Ototoxicity and nephrotoxicity are the most
common side effects associated with Gentamicin
therapy. Both effects are related to renal
impairment and hence the dosage in such
patients should be altered as suggested. In
addition, there have been rare reports of changes
in electrolyte balance including hypocalcaemia
and hypokalaemia caused by renal tubular
dysfunction.
Ear and labyrinth disorders:
Vestibular damage and ototoxicity may occur.
This is usually reversible if observed promptly
and the dose adjusted. Frequency Unknown
(cannot be estimated from the available
data): Irreversible hearing loss, deafness
Renal and urinary disorders
Nephrotoxicity. Frequency Very rare (<
1/10,000).: Acute renal failure, Fanconi-like
syndrome in patients treated with a prolonged
course of high-dose
Immune system disorders
Hypersensitivity, anaphylactic reactions
associated with gentamicin containing therapy.
Blood and lymphatic system disorder
Anemia, blood dyscrasias, granulocytopenia
(reversible)
Nervous system disorders
Convulsions, central nervous system toxicity
(including encephalopathy, confusion, lethargy,
mental depression and hallucinations),
neuromuscular blockade
Hepatobiliary disorders
Hepatic function abnormal
Metabolism and nutrition disorders
Hypomagnesaemia (on prolonged therapy)
Infections and infestations
Combinations of antibiotics containing
gentamicin have been associated with rare
reports of Clostridium difficile diarrhoea.
Gastrointestinal disorders
Stomatitis, nausea, vomiting
Skin and subcutaneous tissue disorders:
Urticaria, allergic contact dermatitis, purpura
Reporting of suspected adverse reactions
Reporting suspected adverse reactions after
authorisation of the medicinal product is
important. It allows continued monitoring of the
benefit/risk balance of the medicinal product.
4.9 Overdose
As in the case of other aminoglycosides, toxicity
is associated with serum levels above a critical
value. In patients with normal renal function it is
unlikely that toxic serum levels (in excess of 10
micrograms/ml) will be reached after
administration of recommended doses. Where
higher levels occur because of renal impairment,
dosage should be reduced. In the event of an
overdose or toxic reaction, peritoneal dialysis or
haemodialysis will lower serum gentamicin
levels. Calcium salts given intravenously have
been used to counter the neuromuscular
blockade caused by gentamicin.
5. PHARMACOLOGICAL PROPERTIES
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5.1 Pharmacodynamic properties
Gentamicin is usually bactericidal in action.
Although the exact mechanism of action has not
been fully elucidated, the drug appears to inhibit
protein synthesis in susceptible bacteria by
irreversibly binding to 30S ribosomal subunits.
In general, gentamicin is active against many
aerobic gram-negative bacteria and some aerobic
gram-positive bacteria. Gentamicin is inactive
against fungi, viruses, and most anaerobic
bacteria.
In vitro, gentamicin concentrations of 1-8 µg/ml
inhibit most susceptible strains of Escherichia
coli, Haemophilus influenzae, Moraxella
lacunata, Neisseria, indole positive and indole
negative Proteus, Pseudomonas (including most
strains of Ps. aeruginosa), Staphylococcus
aureus, S. epidermidis, and Serratia. However,
different species and different strains of the
same species may exhibit wide variations in
susceptibility in vitro. In addition, in
vitro susceptibility does not always correlate
with in vivo activity. Gentamicin is only
minimally active against Streptococci.
Natural and acquired resistance to gentamicin
has been demonstrated in both gram-negative
and gram-positive bacteria. Gentamicin
resistance may be due to decreased permeability
of the bacterial cell wall, alteration in the
ribosomal binding site, or the presence of a
plasmid-mediated resistance factor which is
acquired by conjugation. Plasmid-mediated
resistance enables the resistant bacteria to
enzymatically modify the drug by acetylation,
phosphorylation, or adenylation and can be
transferred between organisms of the same or
different species. Resistance to other
aminoglycosides and several other anti-
infectives (e.g. chloramphenicol, sulphonamides,
tetracycline) may be transferred on the same
plasmid.
There is partial cross-resistance between
gentamicin and other aminoglycosides.
5.2 Pharmacokinetic properties
Distribution
The distribution volume of gentamicin is about
equivalent to the volume of extracellular water.
In the newborn water makes up 70 to 75% of
bodyweight, compared with 50 to 55% in adults.
The extracellular water compartment is larger
(40% of body weight compared with 25% of
body weight in adults). Therefore, the volume of
distribution of gentamicin per kg bodyweight is
affected and decreases with increasing age from
0.5 to 0.7 L/kg for a premature newborn to 0.25
L/kg for an adolescent. The larger volume of
distribution per kg bodyweight means that for
adequate peak blood concentration a higher dose
per kg bodyweight needs to be administered.
Elimination
Gentamicin is not metabolized in the body but is
excreted unchanged in microbiologically active
form predominantly via the kidneys. In patients
with normal renal function the elimination
halflife is about 2 to 3 hours. In neonates
elimination rate is reduced due to immature
renal function.
Elimination half life averages approximately 8
hours in neonates at a gestational age of 26 to 34
weeks compared with about 6.7 hours in
neonates at a gestational age of 35 to 37 weeks.
Correspondingly, clearance values increase from
about 0.05 L/h in neonates at a gestational age of
27 to 0.2 L/h in neonates at a gestational age of
40 weeks.
5.3 Preclinical safety data
There is no pre-clinical data of relevance to the
prescriber which are additional to that already
included in other sections of the SPC.
6. PHARMACEUTICAL PARTICULARS
6.1 List of excipients
Sodium metabisulphite
Disodium edetate
Methyl hydroxybenzoate
Propyl hydroxybenzoate
Water for Injections
Sulphuric acid (2.5N)
Sodium hydroxide (2.5N)
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6.2 Incompatibilities
Gentamicin Injection should not be mixed with
other drugs before injection and where co-
administration of penicillins, cephalosporins,
erythromycin, sulphadiazine, furosemide and
betalactam antibiotics and heparin is necessary,
the drugs should be administered separately,
either as bolus injections into the tubing of the
giving set or at separate sites. Addition of
gentamicin to solutions containing bicarbonate
may lead to the release of carbon dioxide.
6.3 Shelf life
36 months.
6.4 Special precautions for storage
Do not store above 25°C.
6.5 Nature and contents of container
80 mg/2 ml - Clear, Type I glass vials in packs
of 5 vials.
6.6 Special precautions for disposal and other
handling
Not applicable.
7. MANUFACTURER:
Manufactured in India by:
TAJ PHARMACEUTICALS LTD.
Mumbai, India
At: 615, GIDC, Kerala, Bavla, Dist. Ahmedabad
438225, Gujarat, INDIA