This document provides information on pelvic organ prolapse. It defines prolapse as the descent of genital organs through the pelvic floor. It describes the three levels of pelvic support and the types of prolapse that can occur at each level. Symptoms, signs, grading systems, etiology related to childbirth, and risk factors are outlined. Both conservative treatments like pelvic floor exercises and pessaries as well as various surgical repair options to correct prolapse in the anterior, posterior, and apical compartments are summarized.
Disorders of the placenta including: FGR, pre-eclampsia, placental abruption and abnormal (velamentous) cord insertion are associated with over 50% of stillbirths and are frequently cited as the primary cause of death [1–3]. Abnormal placental structure and function significantly increases the risk of stillbirth.
Placenta accreta, placenta increta, and placenta percreta. Abnormal placental implantation (accreta, incretak, and percreta) is described using a general clinical term, respectively, morbidly adherent placenta (MAP) [2] or “abnormal invasive placenta” (AIP).
Menstrual irregularities are the problems with a girl's normal monthly menses. For example, missed periods, have them too frequently, having painful periods, or have excessively heavy flow. Menstrual irregularities can sometimes be a sign of an underlying health problem.
Disorders of the placenta including: FGR, pre-eclampsia, placental abruption and abnormal (velamentous) cord insertion are associated with over 50% of stillbirths and are frequently cited as the primary cause of death [1–3]. Abnormal placental structure and function significantly increases the risk of stillbirth.
Placenta accreta, placenta increta, and placenta percreta. Abnormal placental implantation (accreta, incretak, and percreta) is described using a general clinical term, respectively, morbidly adherent placenta (MAP) [2] or “abnormal invasive placenta” (AIP).
Menstrual irregularities are the problems with a girl's normal monthly menses. For example, missed periods, have them too frequently, having painful periods, or have excessively heavy flow. Menstrual irregularities can sometimes be a sign of an underlying health problem.
Vaginal prolapse is a condition in which structures such as the uterus, rectum, bladder, urethra, small bowel, or the vagina itself may begin to prolapse, or fall out of their normal positions.
Please find the power point on Utero-Vaginal Prolapse. I tried to present it on understandable way and all the contents are reviewed by experts and from very reliable references. Thank you
PELVIC ORGAN PROLAPSE, uterine prolapse , cystocele, rectocele, urethrocele, supports of uterus, sling surgeries, pessaries, grades of prolapse, uterine preserving surgery for pop, pelvic floor repair, vaginal hysterectomy, ward mayos surgery, pop q grading, grading of prolapse, laproscopic surgeries for prolapse, peregee, apogee , mesh repair, tot, tvt, colpo suspension, colpoclysis, SUI management, epidemiology of prolapse, decubitus ulcer, best ppt for pelvic organ prolapse, better understanding of pelvic organ prolapse and pelvic floor.
PELVIC ORGAN PROLAPSE, uterine prolapse , cystocele, rectocele, urethrocele, supports of uterus, sling surgeries, pessaries, grades of prolapse, uterine preserving surgery for pop, pelvic floor repair, vaginal hysterectomy, ward mayos surgery, pop q grading, grading of prolapse, laproscopic surgeries for prolapse, peregee, apogee , mesh repair, tot, tvt, colpo suspension, colpoclysis, SUI management, epidemiology of prolapse, decubitus ulcer, best ppt for pelvic organ prolapse, better understanding of pelvic organ prolapse and pelvic floor. dr . m. gokul reshmi, dr. gokulreshmi m
Abortion Including Recurrent Abortion And Septic Abortion.pptxDeepekaTS
Abortion is defined as the spontaneous or induced termination of pregnancy
before fetal viability. Many prefer miscarriage for spontaneous loss.
abortion as
loss or termination of a pregnancy with a fetus aged younger than 20 weeks’
gestation or weighing <500 g.
Of all miscarriages, approximately half are euploid abortions, that is, carrying a normal chromosomal complement.
Most common abnormalities are
trisomy, found in 50 to 60 percent;
monosomy X, in 9 to 13 percent; and
triploidy, in 11 to 12 percent
A prominent miscarriage risk is associated with poorly
controlled diabetes mellitus, obesity, thyroid disease, and systemic lupus
erythematosus. In these, inflammatory mediators may be an underlying theme
to pregnancy loss.
For women undergoing cancer treatment, direct therapeutic radiation can
cause miscarriage.
Blood loss of >/ 500 ml within 24 hours of vaginal birth or 1000 ml after caesarean section or any blood loss sufficient to compromise haemodynamic instability
MINOR PPH- 500- 1000ml blood loss
MAJOR PPH- > 1000ml Blood loss
MASSIVE PPH- >2000ml Blood loss
Dystocia literally means difficult labor and is characterized by abnormally
slow labor progress.
DYSTOCIA
ABNORMALITIES OF THE EXPULSIVE FORCES
PREMATURELY RUPTURED MEMBRANES AT TERM
PRECIPITOUS LABOR AND DELIVERY
FETOPELVIC DISPROPORTION
FACE PRESENTATION
BROW PRESENTATION
TRANSVERSE LIE
COMPOUND PRESENTATION
COMPLICATIONS WITH DYSTOCIA
Chronic pelvic pain can be defined as intermittent or constant pain in the lower abdomen or pelvis of a woman of at least 6 months in duration, not occurring exclusively with menstruation or intercourse and not associated with pregnancy.
sperm assessment- traditional and novel approaches.pptxDeepekaTS
The latest WHO recommendations,2010 are based on semen parameters from approximately 2000 fertile men, from eight countries and three continents, whose partners achieved pregnancy within 12 months of unprotected sexual intercourse.
Pitfalls- huge shift in the lower reference values, one sided criteria.
Reference limits shouldn’t be over-interpreted
Interpret along with clinical history and physical examination.
Adjuvant therapy, also known as adjunct therapy or add-on therapy, is therapy given in addition to the primary or initial therapy to maximize its effectiveness.
Add-ons have become ubiquitous with the process of assisted reproduction (ART) which is markedly more complex than it was at its inception.
Ovarian stimulation for assisted reproductive technology(ART) cycle aims to provide multiple pre-ovulatory follicles for oocyte collection.
The components of a conventional ART cycle-
Induction of multi-follicular growth with exogenous gonadotropins.
Prevention of endogenous leutinizing hormone (LH) surge by using Gonadotropin releasing hormone(GnRH) analogs.
inducing endogenous LH surge or mimicking it with exogenous human chorionic gonadotropin(hCG) for oocyte maturation.
This concept is known as “CONTROLLED OVARIAN STIMULATION”
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Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
ABDOMINAL TRAUMA in pediatrics part one.drhasanrajab
Abdominal trauma in pediatrics refers to injuries or damage to the abdominal organs in children. It can occur due to various causes such as falls, motor vehicle accidents, sports-related injuries, and physical abuse. Children are more vulnerable to abdominal trauma due to their unique anatomical and physiological characteristics. Signs and symptoms include abdominal pain, tenderness, distension, vomiting, and signs of shock. Diagnosis involves physical examination, imaging studies, and laboratory tests. Management depends on the severity and may involve conservative treatment or surgical intervention. Prevention is crucial in reducing the incidence of abdominal trauma in children.
4. Definition
Genital prolapse is the descent of one or more of the genital
organ (urethra, bladder, uterus, rectum or Douglas pouch or
rectouterine pouch”) through the fasciomuscular pelvic floor
below their normal level.
Vaginal prolapse can occur without uterine prolapse but the
uterus cannot descent without carrying the vagina with it.
5.
6. Supports of PELVIS-De Lancey
Level 1(proximal suspension)
(cervix and upper vagina):
Suspensory axis
Uterosacrals and Cardinal ligaments
Defect apical prolapse (UV Prolapse , enterocele, and
vault prolapse )
7. Level II(lateral attachements)
(mid vaginal support)
Attachment axis
Anterior-pubocervical fascia
Posteriorly :rectovaginal fascia
main supports-arcus tendinus fascia pelvis & arcus
tendinus recto vaginalis
Defects paravaginal & pararectal defects
8. Level III(distal fusion)
• Lower vaginal supports –fusion axis
• Urogenital diaphragm and the perineal body
• Endopelvic fascia
• Defects—posteriorlyRectocele & perineal descent
anteriorly urinary incontinence
9. ETIOLOGY
Vaginal delivery
Prolonged second stage
Rapid successive vaginal delivery
Delivery of macrosomic baby
Instrumental delivery
Premature straining before
complete cervical dilatation
12. Baden-Walker System
The system has five degrees/grades
0 – No prolapse
1 – Leading edge of prolapsed structure descends
halfway to vaginal introitus (hymen)
2 – Leading edge of prolapsed structure descends to the
vaginal introitus
3 – Leading edge of prolapsed structure(s) protrudes up
to halfway outside the vagina
4 – Leading edge of prolapsed structure(s) protrudes
more than halfway outside the vagina
20. Types of prolapse:
1)Vaginal Prolapse:
1) Anterior vaginal wall prolapse:
a. cystocele
b. urethrocele.
c) cysto-urethrocele.
21. 2) Posterior vaginal wall prolapse:
a) enterocele
b)rectocele
c) Perineal descent
22.
23.
24. 3) Vault prolapse:
(descent of the vaginal vault, where the top of the
vagina descends )or inversion of the vagina) after
hysterectomy.
* Vault prolapse is more likely to occur after subtotal than
after total hysterectomy.
25.
26. Symptoms of prolapse:
1. sensation of weakness in the perineum.
2. a mass which appears on straining. and
disappears when she lies down.
3.Discharge ( if ulcer)
27. 3.Urinary symptoms
Urgency and frequency
Stress incontinence.
Inability to micturate unless the anterior vaginal
wall is pushed upwards by the patient's fingers.
4.Rectal symptoms-
incontinence,
incomplete emptying,
straining during defecation,
urgency,
digital pushing
28. 5. Backache,.
6. Leucorrhoea is caused by the congestion and
associated by chronic cervicitis.
7.Sexual dysfunction-dyspareunia,decreased
lubrication
29. Signs
ASSESSMENT OF PROLAPSE
Examined in the lithotomy position- empty bladder
Stress incontinence must be looked for on a full bladder
3 compartment- assessed seperately
Anterior compartment—sims speculum(retracting the
posterior vaginal wall
Middle compartment—by noting the descent of uterus
Posterior compartment-sims speculum (retracting the
anterior vaginal wall)
30. Cystocele and urethrocele looked for by retracting
posterior vaginal wall
Enterocele
Retract the posterior vaginal wall with sims.
Hold the posterior lip of cervix with vulsellum or allis
Cervix is kept reduce at the level ischial spine
Speculum is then slowly withdrawn as the patient is asked to
cough-- bulge appears from above downwards
Rectal examination—ask the patient to strain
Impulse on tip of finger—enterocele
Pulp of finger-rectocele
31. BIMANUAL EXAMINATION
To rule out pelvic mass
ASSESSMENT OF PELVIC FLOOR MUSCLES
Pubococcygeus assessed at 4 and 8 ‘0 clock position
PR Examination – to assess the tone of anal sphincter
PUDENDAL NERVE SENSATION
32. DECUBITUS ULCER
Seen in long standing prolapse
on most dependent part
Cause—venous stasis
Healing is rapid
Non healing ulcer—malignancy should be excluded
33. INVESTIGATIONS:
USG-to rule out pelvic mass and hydronephrosis
renal function test—long standing prolapse
Urodynamic investigations—in case of associated
incontinence
34. DIFFERENTAIL DIAGNOSIS
Gartners cyst- retention cyst – remnants of wolffian duct
Urethral diverticulum
Large fibroid polyps
Chronic inversion
Elongation of cervix
35. Prevention
Proper intra-natal care (during delivery):
Avoid aetiological factors as straining during the first stage(before
full cervical dilatation)
Avoid the application of forceps before full cervical dilatation;
Episiotomy should be done when indicated to avoid hidden perineal
lacerations
Avoid fundal pressure to deliver the placenta.
36. Proper post-natal care (after delivery):
Accurate repair of perineal tears or
episiotomies
Avoidance of occurrence of R.V.F.
Correction of retroversion during the
puerperium
Encourage pelvic floor exercises and other
postnatal ex‘s
prevent puerperal constipation
Care of general health to prevent debility and
bad general health.
GENERAL MEASURES ;treatment of chronic cough
& constipation , correction of obesity
37. MANAGEMENT
CONSERVATIVE MX
Pelvic floor muscle training
PESSARIES—indications
High risk for surgery
Not willing for surgery
Pregnancy
lactation
38. Pessaries
2 types
SUPPORT –Ring pessary
SPACE FILLING-Gelhorn and cube pessary
Ask the patient to cough—to ensure pessary is in place
Ensure that she is able to void urine before leaving clinic
FOLLOW UP
initial—at 2 weeks
First year- 3monthly
afterwards-- 6 monthly
44. 1)WARD- MAYO REPAIR
Vaginal hysterectomy with PFR
Performed where childbearing is complete
Combined with
Enterocele(Mc Call culdoplasty)
Cystocele (anterior colporrhaphy)
Rectocele(colpoperineorrhaphy) correction
45. Mc Call culdoplasty
Approximation of uterosacral
ligaments in the midline so as to
oblieterate the peritoneum of
the posterior cul-de-sac as high
as possible
fixation of uterosacrals to the
vault
46. 2)SACROSPINOUS COLPOPEXY
In case of procidentia
3) ABDOMINOSACROCOLPOPEXY
Abdominal method of apical suspension
4) LE FORT OPERATION/COLPOCLEISIS
Elderly women with medical problems
Total obliteration of vagina –suturing anterior posterior
denuded vagina
47. MANCHESTER /FOTHERGILL’S OPERATION
Women who completed family
Who wishes to retain the uterus
Procedure –anterior colporrhaphyligation of cardinal
ligaments amputation of cervix suturing the cardinal
ligaments to the front of cervix( Fothergills
stitch)reforming the lips of cervix using the vagina
(sturmdorf suture)
Preserves menstrual and reproductive function
48.
49. SHIRODKAR EXTENDED MANCHESTER OR VAGINAL SLING
OPERATION
Modification of Fothergills procedure
Cervical amputation is avoided
Best for women with strong uterosacrals