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General Structure of Ion Channels
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General Structure of Ion Channels
1.
General Structure of
Ion Channels Satadru De M.Phil 1st year
2.
Voltage gated
ion channels: • Na+ channel • K+ channels • Ca2+ channel • Cl- channel Ligand gated ion channels: • Nicotinic Ach-R • GABAA –R • Glycine – R • Ionotropic Glutamate – R • Purinoceptor P2X
3.
Voltage Gated Sodium
Channel
4.
Voltage Gated Calcium
Channel
5.
Voltage Gated Potassium
Channels KA / Fast or Early KV / Delayed Rectifier KS / Serotonin dependant KCa / Calcium dependant Kir / Inward rectifying KATP / ATP dependant Kach / GIRK-1 K leak channels
6.
7.
Chloride Channel (ClC) Chloride-nucleotide
Channel (Cln) Phospholemman Voltage Gated Chloride Channel
8.
Ligand Gated Ion
channels
9.
Nicotinic Ach Receptor
GABAA Receptor
10.
Glycine Receptor
11.
Ionotropic Glutamate Receptor NMDA-Receptor
12.
Purinoceptor – P2X
13.
-End-
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