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General Structure of Ion
Channels
Satadru De
M.Phil 1st year
 Voltage gated ion channels:
• Na+ channel
• K+ channels
• Ca2+ channel
• Cl- channel
 Ligand gated ion channels:
• Nicotinic Ach-R
• GABAA –R
• Glycine – R
• Ionotropic Glutamate – R
• Purinoceptor P2X
Voltage Gated Sodium Channel
Voltage Gated Calcium Channel
Voltage Gated Potassium Channels
KA / Fast or Early
KV / Delayed Rectifier
KS / Serotonin dependant
KCa / Calcium dependant
Kir / Inward rectifying
KATP / ATP dependant
Kach / GIRK-1
K leak channels
Chloride Channel (ClC)
Chloride-nucleotide Channel (Cln)
Phospholemman
Voltage Gated Chloride Channel
Ligand Gated Ion channels
Nicotinic Ach Receptor GABAA Receptor
Glycine Receptor
Ionotropic Glutamate Receptor
NMDA-Receptor
Purinoceptor – P2X
-End-

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General Structure of Ion Channels