The document summarizes the findings of the Global Burden of Diseases, Injuries, and Risk Factors 2010 study conducted by 486 authors from 302 institutions in 50 countries. The study analyzed 291 diseases and injuries, 1,160 disabling sequelae, 67 risk factors, and provided 650 million findings for 187 countries from 1990-2010. Key observations included rapid demographic changes outside sub-Saharan Africa, a progressive disease transition from communicable to non-communicable causes, a disability transition resulting in more years lived with disability, a global risk factor transition, and sub-Saharan Africa still facing a large burden from MDGs 4, 5 and 6.

1. Rapid Health Transitions:
Lessons from the Global Burden of Diseases, Injuries, and
Risk Factors 2010
Dec. 13, 2012

2. GBD 2010 Team
486 authors from 302 institutions in 50 countries
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3. Amassing the best evidence on the state of the
world’s health
• 291 diseases and injuries
• 1,160 disabling sequelae of these diseases and
injuries
• 67 risk factors
• 20 age groups, two sexes
• 187 countries
• 1990-2010
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4. Enhanced scientific rigor for global descriptive
epidemiology
• Statistical methods designed for the challenges of
global health data developed and applied.
• All figures have 95% uncertainty intervals.
• Multiple efforts at validation, e.g., deaths by cause
must add up to 100%; anemia by cause must add
up to total anemia.
• Data visualization environments used as quality
control tools.
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5. Five high-level observations and 650 million
results
• GBD 2010 has 650 million different findings.
• Bird’s-eye view provides five main messages, but
detailed findings are important for many diseases,
injuries, risks and for different regions and countries.
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6. 1) Outside of sub-Saharan Africa rapid demographic change
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7. 2) Progressive disease transition from communicable to
non-communicable causes
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8. 3) The disability transition: progressive shift in burden from
premature mortality to years lived with disability
1990 2010
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9. What ails you is not
necessarily what kills
you: global YLDs by
cause and age, 2010
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10. 4) The
global
risk
factor
transition
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11. 5) The majority of burden in sub-Saharan Africa is still
from MDGs 4, 5 and 6
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12. Leading
causes
of
global
DALYs
shifting
Infectious, neonatal, maternal
Non-communicable
Injuries
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13. Interactive tools to explore GBD 2010
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