This talk presents a series of challenges and opportunities that are emerging for design leaders, managers (and their teams) in a context where startups and established companies are changing their organisations to be lean, modular, product-driven and customer-centric. It consolidates learnings both from my experience in creating a design team in a eduTech company, and from a collection of case studies and opinions gathered among other design managers in agencies and companies: culture, process, cross-team collaboration, accountability, impact on the company are some of the key topics of discussion. This is a common slide deck from a series of different talks, at UX Scotland '15 and UXPA 2015.