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Tony Gershlick UKTony Gershlick UK
Basic (CTO) language
Words you may hear over the next 2 daysWords you may hear over the next 2 days
CART
(Reverse CART)
ₔModified Reverse CART)
CORSAIR
CROSSBOSS
(Stingray)
IVUS-GUIDED
MSCT
ₔOCT
SEPTAL SURFING
SELECTIVE SEPTAL ENGAGEMENT
SUB-INTIMAL TRACKING
TORNUS
Wedgies
Grenadoplasty
CART
(Reverse CART)
ₔModified Reverse CART)
CORSAIR
CROSSBOSS
(Stingray)
IVUS-GUIDED
MSCT
ₔOCT
SEPTAL SURFING
SELECTIVE SEPTAL ENGAGEMENT
SUB-INTIMAL TRACKING
TORNUS
Wedgies
Grenadoplasty
Words you may ALSO hear over the next 2 daysWords you may ALSO hear over the next 2 days
Ok this is going to be difficult to explain
And then the unexpected happened
I was not sure what was going on to be honest
I asked my junior to hold the wire !! !
I’m not 100% sure what actually happened next...
You are going to absolutely love this next bit ....
Mmmm wish I had thought of that ...
And THAT, my friends was the easy part .... “
Ok this is going to be difficult to explain
And then the unexpected happened
I was not sure what was going on to be honest
I asked my junior to hold the wire !! !
I’m not 100% sure what actually happened next...
You are going to absolutely love this next bit ....
Mmmm wish I had thought of that ...
And THAT, my friends was the easy part .... “
私は満足していない 私は手技の進捗に満足していない
DEFINITIONS
Angiographic success :
as final residual stenosis less than 30% with a TIMI grade
flow ≥ than 2
MACE
cardiac death; acute myocardial infarction
or target vessel revascularisation
all deaths cardiac unless otherwise documented
Non-Q wave infarcts CK-MB > 3 x ULN
TVR repeated revascularisation within the treated vessel
Stent Thrombosis ARC definition
CIN increase of 25% or 0.5 mg/dl in serum creatinine at 48 hrs cf baseline
Angiographic success :
as final residual stenosis less than 30% with a TIMI grade
flow ≥ than 2
MACE
cardiac death; acute myocardial infarction
or target vessel revascularisation
all deaths cardiac unless otherwise documented
Non-Q wave infarcts CK-MB > 3 x ULN
TVR repeated revascularisation within the treated vessel
Stent Thrombosis ARC definition
CIN increase of 25% or 0.5 mg/dl in serum creatinine at 48 hrs cf baseline
Antegrade approach
Retrograde approach
Prepping the patient
CTO Appropriateness Criteria
Asymptomatic CCS Class I/II CCS Class III/IV
High Risk
Max Rx
U A A
Int. Risk
Max Rx
U U A
Low Risk
Max Rx
U U A
High Risk
No/Min Rx
I U U
Int. Risk
No/Min Rx
I U U
Low Risk
No/Min Rx
I I I
Typical CTO
Visualization
Challenge
Added CTO Road-
map Data from
MSCT
Co-Registration
CT
framework
Transformation
Projection
Fluoro
framework
You are going to hear a lot about wires and
the techniques
You are going to hear a lot about wires and
the techniques
AnteGAnteG
Micro-cathetersMicro-catheters
Tornus Catheter
Tornus
Tornus 88Flex
Magnified Tornus Tips
Tsuchikane E. CTO Summit 2010
Tip
Distal 20 cm
Proximal
The Asahi Corsair MicrocatheterThe Asahi Corsair Microcatheter
Visibility & Maneuverability –
Tapered Soft Tip & Tungsten Braiding
5mm
Soft tip with
tungsten powder
0.8mm
Platinum
marker coil
The Microchannel Technique
Microscopic section through a
CTO with visible microchannels
separated by thin foils
A stiff guidewire (Miracle 3,
Conquest) is advanced proximal to
the fibrous cap and penetrates
through for 1-2 mm
Enlargement of microchannels by
injection of contrast and nitrates
through an OTW balloon and
subsequent passage of a soft
guidewire
AnteGAnteG
Parallel wire technique
First wire
Second wire
AnteGAnteG
IVUS to identify entry point“IVUS GUIDED
………….”
Wedgie
?
?
Antegrade
Retrograde
Dissection Re-Entry
Retrograde
Tracks via FAST SPIN technique
•Spin should reduce push required
•Highly torqueable shaft
0.014" guidewire
compatible (OTW)
Atraumatic 3F
rounded distal tip
2.3F shaft profile
The CrossBoss™ CTO Catheter
Procedural approach
Septal Surfing (George Siannos)
The guidewre (often Sion) advanced rapidly until it
either buckles or advances into the distal target vessel
If it buckles it is withdrawn and re advanced
Probably should avoid epicardial collaterals
Retract sufficiently
Do not push hard
Success higher in proximal straighter collaterals
RAO cranial for initial wiring
RAO caudial for turning into posterior descending
Contrast Surfing
3 mls luer lock syringe neat contrast
Aspirate until blood enters syringe
Cine while (gently) injecting
Flush micro-catheter before reengaging guidewire
(stickiness)
Do not pan
RAO caudal for distal part
LAO also
CART: controlled antegrade and retrograde
sub-intimal tracking technique
¤ The balloon is kept in place to keep the subintimal space open
¤ The antegrade wire is advanced further along the deflated retrograde
balloon that lies from the subintimal space to the distal true lumen
¤ Dilatation and stent implantation in the usual manner
Variations of Reverse CARTVariations of Reverse CART
IVUS –Guided Reverse CART
Allow more precise sizing balloon
and determine if significant recoil
Repeated balloon
Larger Balloon
Snare
Now Guide cath extensions
Punctured Reverse CART
Stiff wire to puncture balloon and deflated balloon withdrawn
Stent Reverse CART
Confluent Balloon Reverse CART
3. Modified Reverse CART = antegrade ballooning + retrograde wirin
But not into sub-intimal space (into side branch)
3. Modified Reverse CART = antegrade ballooning + retrograde wirin
But not into sub-intimal space (into side branch)
Tornado®
(Cook Medical)
Embolization Coils Microspheres
Embozene TM
(CeloNova BioSciences)
Hybrid CTO PCI Strategy
Hybrid
Strategy
Simple
retrograde
Complex
Antegrade
Complex
Retrograde
Simple
Antegrade
Step ApproachAlgorithm (C)
• Ambiguous proximal cap
• Good interventional
collaterals
Talking enthusiastically and
excitedly about CTO without the
need to breath
“Lombardiitis”
Inability to find
a theatre cap to fit
“Freddiitis” Smiling charmingly
while indicating your
data are really poor
“Di Mario-ism”
Impossible is a word to be
found only in the dictionary
of fools.
Napoleon Bonaparte
Impossible is a word to be
found only in the dictionary
of fools.
Napoleon Bonaparte
PTFE Coat
・ Length over all ; 1900
・Coil length ; 160
・Radio paque ; 160
Unit ; (mm)
straigh
t
taper
3010
0.014Inch
Urethan + Hydrophilic Polymer
Coat
0.009Inch
Fielder XT
0.014Inch
Hydrophilic Polymer Coat
PTFE Coat
Rop
e
Unit ; (mm)
・ Length over all ; 1800
・Coil length ; 280
・Radio paque ; 30
Actone
Sion
Fielder
FC
Fielder SION SION
blue
XT XT-R ULTIMATE
blos3
1mm
Shaping of the Wire Tip
1. CART = retrograde ballooning + antegrade wiring1. CART = retrograde ballooning + antegrade wiring
2. Reverse CART = antegrade ballooning + retrograde wiring2. Reverse CART = antegrade ballooning + retrograde wiring
2b IVUS guided reverse CART2b IVUS guided reverse CART
Recanalization Using Controlled Antegrade and Retrograde
Subintimal Tracking:
Recanalization Using Controlled Antegrade and Retrograde
Subintimal Tracking:
3. Modified Reverse CART = antegrade ballooning + retrograde wirin
But not into sub-intimal space (into side branch)
3. Modified Reverse CART = antegrade ballooning + retrograde wirin
But not into sub-intimal space (into side branch)
O.Dφ0.71
I.Dφ0.46
Tornus Catheter
Tornus-Pro φ0.10㎜×10wires same as Corsair
1350mm
Sleeve300mm 75mm
O.Dφ0.70
I.Dφ0.50
1mm Taper Tip
O.D(φ0.67)
I.Dφ0.41
O.Dφ1.1
Non-Tapered
1350mm
Long Tapered 150mm Sleeve300mm 75mm
Tip O.Dφ0.61
I.Dφ0.41
O.Dφ1.1
Tornus φ0.12㎜×8wires
Tsuchikane E. CTO Summit 2010
Tornus Pro
Unpolished shaft
Maximizes the screw effect to pass through
tight lesions
Tornus Catheter
Tornus Pro(Unpolished) Tornus ( Polished)
Features and Benefits of Tornus Pro
Tsuchikane E. CTO Summit 2010
Lesion Morphology
Echolucent
plaque
Aneurysm
with
thrombus
Layered
plaque
Incidence
0
10
20
30
Ruptured
plaque
Echolucent Plaque Layered PlaqueRuptured Plaque
88 CTO
lesions
Tsujita K. ACC 2008
IVUS Findings: Perforation
Maehara A. CTO Summit 2010
Moses JW. CTO Summit 2010
Pre-Procedure
MSCT 3-D Image
Intra-Procedure
Real-Time 2-D
Fluoroscopy
Intra-Procedure C-
Arm CT 3-D
Image
Intervention
Guidance Using
Overlaid Images
Co-Registration
Modalities and Process
CT / Fluoro Fusion
Moses JW. CTO Summit 2010
Calcification
Septal
Diagonal branch
CTO Toyohashi Heart Center
Slides courtesy of Etsuo Tsuchikane
A B C
D E F
G
Guidewire not jailed: dangerous!!
H I
The STAR Technique
‘Child in Mother’ Technique
Case 3 Subintimal Dissection
Anchor balloon
Procedural approach
XX
Or !!!
Balloon
antegrade on
retrograde wire
X
X
Concept of CART technique
- Controlled Antegrade and Retrograde subintimal Tracking
-
Concept of CART technique
- Controlled Antegrade and Retrograde subintimal Tracking
-
¤Simultaneous use of the
antegrade and retrograde
approaches
¤Create a subintimal dissection by
inflating a small (1.5-2.0mm
balloon) over the retrograde wire
CART
Reverse CART
Parallel wire technique
First wire
Second wire

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Friday 08:01 - Gershlick- Basic CTO Terminology

  • 1. Tony Gershlick UKTony Gershlick UK Basic (CTO) language
  • 2. Words you may hear over the next 2 daysWords you may hear over the next 2 days CART (Reverse CART) ₔModified Reverse CART) CORSAIR CROSSBOSS (Stingray) IVUS-GUIDED MSCT ₔOCT SEPTAL SURFING SELECTIVE SEPTAL ENGAGEMENT SUB-INTIMAL TRACKING TORNUS Wedgies Grenadoplasty CART (Reverse CART) ₔModified Reverse CART) CORSAIR CROSSBOSS (Stingray) IVUS-GUIDED MSCT ₔOCT SEPTAL SURFING SELECTIVE SEPTAL ENGAGEMENT SUB-INTIMAL TRACKING TORNUS Wedgies Grenadoplasty
  • 3. Words you may ALSO hear over the next 2 daysWords you may ALSO hear over the next 2 days Ok this is going to be difficult to explain And then the unexpected happened I was not sure what was going on to be honest I asked my junior to hold the wire !! ! I’m not 100% sure what actually happened next... You are going to absolutely love this next bit .... Mmmm wish I had thought of that ... And THAT, my friends was the easy part .... “ Ok this is going to be difficult to explain And then the unexpected happened I was not sure what was going on to be honest I asked my junior to hold the wire !! ! I’m not 100% sure what actually happened next... You are going to absolutely love this next bit .... Mmmm wish I had thought of that ... And THAT, my friends was the easy part .... “ 私は満足していない 私は手技の進捗に満足していない
  • 5. Angiographic success : as final residual stenosis less than 30% with a TIMI grade flow ≥ than 2 MACE cardiac death; acute myocardial infarction or target vessel revascularisation all deaths cardiac unless otherwise documented Non-Q wave infarcts CK-MB > 3 x ULN TVR repeated revascularisation within the treated vessel Stent Thrombosis ARC definition CIN increase of 25% or 0.5 mg/dl in serum creatinine at 48 hrs cf baseline Angiographic success : as final residual stenosis less than 30% with a TIMI grade flow ≥ than 2 MACE cardiac death; acute myocardial infarction or target vessel revascularisation all deaths cardiac unless otherwise documented Non-Q wave infarcts CK-MB > 3 x ULN TVR repeated revascularisation within the treated vessel Stent Thrombosis ARC definition CIN increase of 25% or 0.5 mg/dl in serum creatinine at 48 hrs cf baseline
  • 7. Prepping the patient CTO Appropriateness Criteria Asymptomatic CCS Class I/II CCS Class III/IV High Risk Max Rx U A A Int. Risk Max Rx U U A Low Risk Max Rx U U A High Risk No/Min Rx I U U Int. Risk No/Min Rx I U U Low Risk No/Min Rx I I I Typical CTO Visualization Challenge Added CTO Road- map Data from MSCT
  • 9. You are going to hear a lot about wires and the techniques You are going to hear a lot about wires and the techniques AnteGAnteG
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  • 13. Tornus Catheter Tornus Tornus 88Flex Magnified Tornus Tips Tsuchikane E. CTO Summit 2010
  • 14. Tip Distal 20 cm Proximal The Asahi Corsair MicrocatheterThe Asahi Corsair Microcatheter Visibility & Maneuverability – Tapered Soft Tip & Tungsten Braiding 5mm Soft tip with tungsten powder 0.8mm Platinum marker coil
  • 15. The Microchannel Technique Microscopic section through a CTO with visible microchannels separated by thin foils A stiff guidewire (Miracle 3, Conquest) is advanced proximal to the fibrous cap and penetrates through for 1-2 mm Enlargement of microchannels by injection of contrast and nitrates through an OTW balloon and subsequent passage of a soft guidewire AnteGAnteG
  • 16. Parallel wire technique First wire Second wire AnteGAnteG
  • 17. IVUS to identify entry point“IVUS GUIDED ………….”
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  • 23. Tracks via FAST SPIN technique •Spin should reduce push required •Highly torqueable shaft 0.014" guidewire compatible (OTW) Atraumatic 3F rounded distal tip 2.3F shaft profile The CrossBoss™ CTO Catheter
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  • 28. Septal Surfing (George Siannos) The guidewre (often Sion) advanced rapidly until it either buckles or advances into the distal target vessel If it buckles it is withdrawn and re advanced Probably should avoid epicardial collaterals Retract sufficiently Do not push hard Success higher in proximal straighter collaterals RAO cranial for initial wiring RAO caudial for turning into posterior descending
  • 29. Contrast Surfing 3 mls luer lock syringe neat contrast Aspirate until blood enters syringe Cine while (gently) injecting Flush micro-catheter before reengaging guidewire (stickiness) Do not pan RAO caudal for distal part LAO also
  • 30. CART: controlled antegrade and retrograde sub-intimal tracking technique ¤ The balloon is kept in place to keep the subintimal space open ¤ The antegrade wire is advanced further along the deflated retrograde balloon that lies from the subintimal space to the distal true lumen ¤ Dilatation and stent implantation in the usual manner
  • 31. Variations of Reverse CARTVariations of Reverse CART IVUS –Guided Reverse CART Allow more precise sizing balloon and determine if significant recoil Repeated balloon Larger Balloon Snare Now Guide cath extensions Punctured Reverse CART Stiff wire to puncture balloon and deflated balloon withdrawn Stent Reverse CART Confluent Balloon Reverse CART 3. Modified Reverse CART = antegrade ballooning + retrograde wirin But not into sub-intimal space (into side branch) 3. Modified Reverse CART = antegrade ballooning + retrograde wirin But not into sub-intimal space (into side branch)
  • 32.
  • 33. Tornado® (Cook Medical) Embolization Coils Microspheres Embozene TM (CeloNova BioSciences)
  • 34. Hybrid CTO PCI Strategy Hybrid Strategy Simple retrograde Complex Antegrade Complex Retrograde Simple Antegrade
  • 35. Step ApproachAlgorithm (C) • Ambiguous proximal cap • Good interventional collaterals
  • 36. Talking enthusiastically and excitedly about CTO without the need to breath “Lombardiitis” Inability to find a theatre cap to fit “Freddiitis” Smiling charmingly while indicating your data are really poor “Di Mario-ism”
  • 37. Impossible is a word to be found only in the dictionary of fools. Napoleon Bonaparte Impossible is a word to be found only in the dictionary of fools. Napoleon Bonaparte
  • 38.
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  • 44. PTFE Coat ・ Length over all ; 1900 ・Coil length ; 160 ・Radio paque ; 160 Unit ; (mm) straigh t taper 3010 0.014Inch Urethan + Hydrophilic Polymer Coat 0.009Inch Fielder XT
  • 45. 0.014Inch Hydrophilic Polymer Coat PTFE Coat Rop e Unit ; (mm) ・ Length over all ; 1800 ・Coil length ; 280 ・Radio paque ; 30 Actone Sion
  • 46. Fielder FC Fielder SION SION blue XT XT-R ULTIMATE blos3 1mm Shaping of the Wire Tip
  • 47. 1. CART = retrograde ballooning + antegrade wiring1. CART = retrograde ballooning + antegrade wiring 2. Reverse CART = antegrade ballooning + retrograde wiring2. Reverse CART = antegrade ballooning + retrograde wiring 2b IVUS guided reverse CART2b IVUS guided reverse CART Recanalization Using Controlled Antegrade and Retrograde Subintimal Tracking: Recanalization Using Controlled Antegrade and Retrograde Subintimal Tracking: 3. Modified Reverse CART = antegrade ballooning + retrograde wirin But not into sub-intimal space (into side branch) 3. Modified Reverse CART = antegrade ballooning + retrograde wirin But not into sub-intimal space (into side branch)
  • 48.
  • 49. O.Dφ0.71 I.Dφ0.46 Tornus Catheter Tornus-Pro φ0.10㎜×10wires same as Corsair 1350mm Sleeve300mm 75mm O.Dφ0.70 I.Dφ0.50 1mm Taper Tip O.D(φ0.67) I.Dφ0.41 O.Dφ1.1 Non-Tapered 1350mm Long Tapered 150mm Sleeve300mm 75mm Tip O.Dφ0.61 I.Dφ0.41 O.Dφ1.1 Tornus φ0.12㎜×8wires Tsuchikane E. CTO Summit 2010 Tornus Pro
  • 50. Unpolished shaft Maximizes the screw effect to pass through tight lesions Tornus Catheter Tornus Pro(Unpolished) Tornus ( Polished) Features and Benefits of Tornus Pro Tsuchikane E. CTO Summit 2010
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  • 56. Moses JW. CTO Summit 2010 Pre-Procedure MSCT 3-D Image Intra-Procedure Real-Time 2-D Fluoroscopy Intra-Procedure C- Arm CT 3-D Image Intervention Guidance Using Overlaid Images Co-Registration Modalities and Process
  • 57. CT / Fluoro Fusion Moses JW. CTO Summit 2010 Calcification Septal Diagonal branch
  • 58. CTO Toyohashi Heart Center Slides courtesy of Etsuo Tsuchikane A B C D E F G Guidewire not jailed: dangerous!! H I The STAR Technique
  • 60.
  • 61. Case 3 Subintimal Dissection
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  • 73. X
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  • 76. X
  • 77. Concept of CART technique - Controlled Antegrade and Retrograde subintimal Tracking - Concept of CART technique - Controlled Antegrade and Retrograde subintimal Tracking - ¤Simultaneous use of the antegrade and retrograde approaches ¤Create a subintimal dissection by inflating a small (1.5-2.0mm balloon) over the retrograde wire
  • 78. CART
  • 80.
  • 81.
  • 82. Parallel wire technique First wire Second wire