This document discusses the antegrade approach for treating chronic total occlusions (CTOs). The goals are to restore the original artery anatomy with minimal damage or time/resources. The antegrade approach involves analyzing the lesion and patient, using a step-by-step process starting with softer wires and progressing if needed. Parallel wiring is an early bailout option. Guided reentry may be used if retrograde proves difficult. The strategy aims to select the approach most likely to succeed for each specific lesion and patient.