The laboratory notebook is an essential working tool for the researcher. It is used for documenting and dating any experiments, work, research results and original ideas. Laboratory notebook is the memory of the researchers (traceability) and an element for excellence and professionalism in the field of scientific research. Additionally, it can be considered as an essential tool to protect the research results and as a key element in the technology transfer policy. This laboratory notebook established by the LIEU network was adopted simultaneously by all the French speaking universities in Belgium in 2005.
www.FITT-for-Innovation.eu
Developing Standerd Structure for Medical LaboratoryRavi Kumudesh
Needs for Developing
National Health Laboratory Policy and Plan
Laboratory Techniques and Procedures
Manpower and HR
Clinical Laboratory Information Systems.
Equipment and Supplies.
Guidelines and Regulations
Essential Elements of Laboratory Management
Human resource management
Quality management systems
Procurement and supplies management
Laboratory equipment management
Laboratory information management system
Safety and waste management
Laboratory financing
Developing Standerd Structure for Medical LaboratoryRavi Kumudesh
Needs for Developing
National Health Laboratory Policy and Plan
Laboratory Techniques and Procedures
Manpower and HR
Clinical Laboratory Information Systems.
Equipment and Supplies.
Guidelines and Regulations
Essential Elements of Laboratory Management
Human resource management
Quality management systems
Procurement and supplies management
Laboratory equipment management
Laboratory information management system
Safety and waste management
Laboratory financing
Each person in the laboratory should maintain a hardbound laboratory notebook with
continuously numbered pages as a permanent record of his or her work and ideas.
Talk given for UW-Madison Ebling Library and School of Medicine and Public Health on 3 Dec 2013. It covers electronic laboratory notebooks and what to look for in the software.
Lab Notebooks as Data Management (SLA Winter Virtual Conference 2012)Kristin Briney
This talk, aimed at librarians, describes the data management issues surrounding paper and electronic lab notebooks. It offers several ways for librarians to support good practices and the transition from paper to electronic.
Challenges and Guidelines for Reproducible Research with Jupyter NotebookPeter Rose
Poster from JupyterCon 2018:
Jupyter Notebooks are extensively used in research and education. We recently organized a workshop at UC San Diego and invited students, postdocs, research scientists, and faculty to share experiences and identify challenges of using Jupyter notebooks. The workshop covered the use of Jupyter in many disciplines, ranging from Astrophysics, Bioinformatics, Datascience, Genomics, Medicine, to Structural Bioinformatics, as well as classroom use with hundreds of students and publication of reproducible science. Here we present a summary of our findings in the form of guidelines.
We are crowdsourcing a guide on reproducible research and data science at: https://github.com/sbl-sdsc/jupyter-guide.
We welcome your suggestions and contributions to this community-guide.
OAPEN started its activities on September 1, 2008 and has now completed its project phase co-funded by the European Commission. The final stage of the project focused on the launch of the OAPEN Library, usability, and especially sustainability after the project period. The results were presented during the final conference in Berlin in February 2011.
In the future OAPEN will continue as an independent foundation governed by representatives of the participating institutions. The objectives for the foundation are to stimulate further OA publishing of academic books, to further develop OAPEN as a platform for OA books and to develop a sustainable business model. In the meantime, OAPEN is conducting a number of experiments in Open Access book publishing, in the form of pilot projects. The first pilot is conducted in the Netherlands with support from the Netherlands Organization for Scientific Research (NWO) and the Ministry of Education. For the UK a similar pilot project is being prepared by JISC Collections.
Presentation by Phil Taylor and Dario Faniglione for the Higher Education Academy (HEA) symposium at BERA Annual Conference in London, September 2014.
The project, one of four projects supported by the HEA in 2014, has created an app which can be used by student teachers and other practitioners to carry out both individual and collaborative research,
Further details can be found in the project report at http://bit.ly/ZpLMfU
An introductory talk for librarians on why laboratory notebooks are a critical tool for data management in scientific research. I also suggest ways that academic librarians can help scientists better manage their data in this area.
Stellenbosch University Library and Information Service Carnegie Research Com...Reed Elsevier
This slideshow presents an image-based overview of the Carnegie Research Commons at Stellenbosch University including reference to the concepts, context, facilities, services, activities, staff and general aspects related to the facility located in the JS Gericke Library, Stellenbosch.
An overview of the current state of electronic laboratory notebooks (ELNs), pros and cons of using an ELN, and important considerations for adopting an ELN.
What is expected from the group 4 project?
Interdisciplinary collaboration
Appreciation of the implications of science and the limitations of scientific study
Development of teamwork
Development of planning skills
Exchange or sharing of both data collected and issues raised.
Approximately 10 hours of involvement time.
Members' Sharing Session presentation delivered by Mark Tynan and Lorraine Foster at the 2009 BBSLG Conference hosted by the Irish Management Institute, 1-3 July 2009.
Presentation to meeting, Heraklion, 4th June 2014 on constructing a marine virtual laboratory from the bottom up in the context of LifeWatch. Covers:
- Constructing LifeWatch – reminders of what we are doing
- Sourcing the right ingredients - The “Service Network” idea
- Steps towards building Virtual Laboratories.
Prof. Thomas Baaken:Science-to-Business Marketing - A new Model in Knowledge ...FITT
This presentation was held by Prof. Thomas Baaken during the FITT conference „ICT Innovations: Research > Business > Society“ on 10 May 2011 in Brussels.
www.fitt-for-innovation.eu
Mario Cameron: Turning Science into Business: From Research to Market – the E...FITT
This presentation was held by Dr. Mario T. Cameron during the FITT conference „ICT Innovations: Research > Business > Society“ on 10 May 2011 in Brussels.
www.fitt-for-innovation.eu
Each person in the laboratory should maintain a hardbound laboratory notebook with
continuously numbered pages as a permanent record of his or her work and ideas.
Talk given for UW-Madison Ebling Library and School of Medicine and Public Health on 3 Dec 2013. It covers electronic laboratory notebooks and what to look for in the software.
Lab Notebooks as Data Management (SLA Winter Virtual Conference 2012)Kristin Briney
This talk, aimed at librarians, describes the data management issues surrounding paper and electronic lab notebooks. It offers several ways for librarians to support good practices and the transition from paper to electronic.
Challenges and Guidelines for Reproducible Research with Jupyter NotebookPeter Rose
Poster from JupyterCon 2018:
Jupyter Notebooks are extensively used in research and education. We recently organized a workshop at UC San Diego and invited students, postdocs, research scientists, and faculty to share experiences and identify challenges of using Jupyter notebooks. The workshop covered the use of Jupyter in many disciplines, ranging from Astrophysics, Bioinformatics, Datascience, Genomics, Medicine, to Structural Bioinformatics, as well as classroom use with hundreds of students and publication of reproducible science. Here we present a summary of our findings in the form of guidelines.
We are crowdsourcing a guide on reproducible research and data science at: https://github.com/sbl-sdsc/jupyter-guide.
We welcome your suggestions and contributions to this community-guide.
OAPEN started its activities on September 1, 2008 and has now completed its project phase co-funded by the European Commission. The final stage of the project focused on the launch of the OAPEN Library, usability, and especially sustainability after the project period. The results were presented during the final conference in Berlin in February 2011.
In the future OAPEN will continue as an independent foundation governed by representatives of the participating institutions. The objectives for the foundation are to stimulate further OA publishing of academic books, to further develop OAPEN as a platform for OA books and to develop a sustainable business model. In the meantime, OAPEN is conducting a number of experiments in Open Access book publishing, in the form of pilot projects. The first pilot is conducted in the Netherlands with support from the Netherlands Organization for Scientific Research (NWO) and the Ministry of Education. For the UK a similar pilot project is being prepared by JISC Collections.
Presentation by Phil Taylor and Dario Faniglione for the Higher Education Academy (HEA) symposium at BERA Annual Conference in London, September 2014.
The project, one of four projects supported by the HEA in 2014, has created an app which can be used by student teachers and other practitioners to carry out both individual and collaborative research,
Further details can be found in the project report at http://bit.ly/ZpLMfU
An introductory talk for librarians on why laboratory notebooks are a critical tool for data management in scientific research. I also suggest ways that academic librarians can help scientists better manage their data in this area.
Stellenbosch University Library and Information Service Carnegie Research Com...Reed Elsevier
This slideshow presents an image-based overview of the Carnegie Research Commons at Stellenbosch University including reference to the concepts, context, facilities, services, activities, staff and general aspects related to the facility located in the JS Gericke Library, Stellenbosch.
An overview of the current state of electronic laboratory notebooks (ELNs), pros and cons of using an ELN, and important considerations for adopting an ELN.
What is expected from the group 4 project?
Interdisciplinary collaboration
Appreciation of the implications of science and the limitations of scientific study
Development of teamwork
Development of planning skills
Exchange or sharing of both data collected and issues raised.
Approximately 10 hours of involvement time.
Members' Sharing Session presentation delivered by Mark Tynan and Lorraine Foster at the 2009 BBSLG Conference hosted by the Irish Management Institute, 1-3 July 2009.
Presentation to meeting, Heraklion, 4th June 2014 on constructing a marine virtual laboratory from the bottom up in the context of LifeWatch. Covers:
- Constructing LifeWatch – reminders of what we are doing
- Sourcing the right ingredients - The “Service Network” idea
- Steps towards building Virtual Laboratories.
Prof. Thomas Baaken:Science-to-Business Marketing - A new Model in Knowledge ...FITT
This presentation was held by Prof. Thomas Baaken during the FITT conference „ICT Innovations: Research > Business > Society“ on 10 May 2011 in Brussels.
www.fitt-for-innovation.eu
Mario Cameron: Turning Science into Business: From Research to Market – the E...FITT
This presentation was held by Dr. Mario T. Cameron during the FITT conference „ICT Innovations: Research > Business > Society“ on 10 May 2011 in Brussels.
www.fitt-for-innovation.eu
Clustering and networking activities are relationship-based activities that support sharing and developing of competences, knowledge and methods. The documents within the toolbox have a clear focus on activities in the area of technology transfer. Networking and clustering activities are critical leverages for all transfer activities presented in this toolbox, namely: opportunities identification, IP management, Human resources and focused value proposition.
www.FITT-for-Innovation.eu
The presented Network Scorecard suite is a method aimed at supporting the strategic and operational management processes of networks. It relies on three principles: It is a participatory approach, where the networks key actors jointly define a shared vision of their networks performance. Moreover, its integrated approach covers the management cycle of the network including the definition of a strategy, a plan of action and a scorecard. And finally, it structures a network performance on four dimensions: the benefits to the members, implication of the members, external context and organization. The practice presents all necessary steps to involve the key actors of the network and structure the process.
www.FITT-for-Innovation.eu
Cluster Managers have expressed their interest in innovative tools that bundle knowledge and is continuously updated. To meet their demands, MFG has implemented an interactive Cluster Manual based on the Wiki principle. The Cluster Manual gives cluster newbies a ‘basic’ guideline and offers cluster managers an in-depth source for every aspect of cluster issues. Additionally, it documents success stories and best practice examples to build up a repository of internal generated knowledge (‘learn from the best’), gives an overview of the most important literature in the area of Cluster Management and combines all this with the knowledge of experts.
www.FITT-for-Innovation.eu
The Balanced Scorecard methodology is used, to give mangers a tool for translating a strategy or a vision into actions and to reach the set targets. The MFG Balanced Scorecard gives cluster managers a tool for managing their cluster initiatives by defining concrete objectives based on their vision and strategy. The Balanced Scorecard methodology helps to clarify and translate vision and strategy, to communicate and link strategic objectives with actions, to plan, set and align strategic initiatives and to enhance strategic feedback and learning.
www.FITT-for-Innovation.eu
Professional tools for cluster or network management are more important than ever as the management plays a decisive role for the success or the failure of a cluster initiative/network. Today there are no general cluster/network management methods available to optimize the management. The presented practices use the Balanced Scorecard method which gives the mangers a tool to professionalize the management and to monitor activities including measuring successes.
www.FITT-for-Innovation.eu
FITT Toolbox: International Technology Transfer NetworksFITT
Many international networks are active in the field of technology transfer and give the opportunity to: be in touch with pairs at the international level, access to training and seminars, exchange of good practices and experiences, find partners or investors, promote an innovation and much more. The choice of the network of which you could be a member can be a challenge. The goal of this practice is to give you a quick overview of the existing organisations, and can be a guide for the choice of such a network.
The presented online cooperation platform was developed to give cluster managers and other cluster stakeholders access to current information and trends. It is set up in form of a Social Network on the topic ‘cluster management’ and offers users/members a central information tool, where knowledge is documented and exchange is fostered. Therefore it is an efficient way to foster exchange between experts, to build up a repository of knowledge including success stories and to present the topic to a broader public.
www.FITT-for-Innovation.eu
The network support services support the networks' sustainability by providing a set of logistics and communication services. Access to these services is conditioned by an agreement between the technology transfer officer and the network and the compliance with a charter. This agreement creates the conditions for a long-term cooperation and a win win situation: the networks gain access to free logistics and communication services, while the transfer officer gains access to strategic information from the field, the opportunity to develop specific partnerships and legitimacy.
www.FITT-for-Innovation.eu
FITT Toolbox: Technology Transfer (TT) CollaborationFITT
The chapter TT collaboration addresses the topic of networking at two levels: Firstly, the added value of participating in networks for people active in technology transfer is highlighted at an international level. Additionally, at a local level, technology transfer network with local actors reinforces their local embeddings and grants a privileged, neutral and legitimate channel for two-ways transfer between transfer officers and other stakeholders.
www.FITT-for-Innovation.eu
The presented case study is about Siruna NV, which has developed software for real time deployment of mobile websites through a dual Open Source business model. Although this model is not widely adapted, this model can be easily copied as far as it helps to cover development costs by the help of a large and free developer community, helps to market the product, quickly, sets a reference in a rapidly evolving market and succeeds in creating value within an open source setting.
www.FITT-for-Innovation.eu
Dr. Carolina Garcia Rizo: Commercializing Innovative Technologies: The US Per...FITT
This presentation was held by Dr. Carolina Garcia Rizo during the FITT conference „ICT Innovations: Research > Business > Society“ on 10 May 2011 in Brussels.
www.fitt-for-innovation.eu
The Business Model Design practice supports the definition of a sustainable business model, collaboratively with all its stakeholders. To Technology Transfer Officers this practice proposes reference canvas and tools easily tailored to support most business strategic decision. To researchers, this practice is in essence a way to promote a sound business culture and a set of tools to facilitate the design of a business model. Its foundation from the design science make it practical and result oriented.
www.FITT-for-Innovation.eu
State of ICS and IoT Cyber Threat Landscape Report 2024 previewPrayukth K V
The IoT and OT threat landscape report has been prepared by the Threat Research Team at Sectrio using data from Sectrio, cyber threat intelligence farming facilities spread across over 85 cities around the world. In addition, Sectrio also runs AI-based advanced threat and payload engagement facilities that serve as sinks to attract and engage sophisticated threat actors, and newer malware including new variants and latent threats that are at an earlier stage of development.
The latest edition of the OT/ICS and IoT security Threat Landscape Report 2024 also covers:
State of global ICS asset and network exposure
Sectoral targets and attacks as well as the cost of ransom
Global APT activity, AI usage, actor and tactic profiles, and implications
Rise in volumes of AI-powered cyberattacks
Major cyber events in 2024
Malware and malicious payload trends
Cyberattack types and targets
Vulnerability exploit attempts on CVEs
Attacks on counties – USA
Expansion of bot farms – how, where, and why
In-depth analysis of the cyber threat landscape across North America, South America, Europe, APAC, and the Middle East
Why are attacks on smart factories rising?
Cyber risk predictions
Axis of attacks – Europe
Systemic attacks in the Middle East
Download the full report from here:
https://sectrio.com/resources/ot-threat-landscape-reports/sectrio-releases-ot-ics-and-iot-security-threat-landscape-report-2024/
UiPath Test Automation using UiPath Test Suite series, part 4DianaGray10
Welcome to UiPath Test Automation using UiPath Test Suite series part 4. In this session, we will cover Test Manager overview along with SAP heatmap.
The UiPath Test Manager overview with SAP heatmap webinar offers a concise yet comprehensive exploration of the role of a Test Manager within SAP environments, coupled with the utilization of heatmaps for effective testing strategies.
Participants will gain insights into the responsibilities, challenges, and best practices associated with test management in SAP projects. Additionally, the webinar delves into the significance of heatmaps as a visual aid for identifying testing priorities, areas of risk, and resource allocation within SAP landscapes. Through this session, attendees can expect to enhance their understanding of test management principles while learning practical approaches to optimize testing processes in SAP environments using heatmap visualization techniques
What will you get from this session?
1. Insights into SAP testing best practices
2. Heatmap utilization for testing
3. Optimization of testing processes
4. Demo
Topics covered:
Execution from the test manager
Orchestrator execution result
Defect reporting
SAP heatmap example with demo
Speaker:
Deepak Rai, Automation Practice Lead, Boundaryless Group and UiPath MVP
Connector Corner: Automate dynamic content and events by pushing a buttonDianaGray10
Here is something new! In our next Connector Corner webinar, we will demonstrate how you can use a single workflow to:
Create a campaign using Mailchimp with merge tags/fields
Send an interactive Slack channel message (using buttons)
Have the message received by managers and peers along with a test email for review
But there’s more:
In a second workflow supporting the same use case, you’ll see:
Your campaign sent to target colleagues for approval
If the “Approve” button is clicked, a Jira/Zendesk ticket is created for the marketing design team
But—if the “Reject” button is pushed, colleagues will be alerted via Slack message
Join us to learn more about this new, human-in-the-loop capability, brought to you by Integration Service connectors.
And...
Speakers:
Akshay Agnihotri, Product Manager
Charlie Greenberg, Host
UiPath Test Automation using UiPath Test Suite series, part 3DianaGray10
Welcome to UiPath Test Automation using UiPath Test Suite series part 3. In this session, we will cover desktop automation along with UI automation.
Topics covered:
UI automation Introduction,
UI automation Sample
Desktop automation flow
Pradeep Chinnala, Senior Consultant Automation Developer @WonderBotz and UiPath MVP
Deepak Rai, Automation Practice Lead, Boundaryless Group and UiPath MVP
Neuro-symbolic is not enough, we need neuro-*semantic*Frank van Harmelen
Neuro-symbolic (NeSy) AI is on the rise. However, simply machine learning on just any symbolic structure is not sufficient to really harvest the gains of NeSy. These will only be gained when the symbolic structures have an actual semantics. I give an operational definition of semantics as “predictable inference”.
All of this illustrated with link prediction over knowledge graphs, but the argument is general.
Key Trends Shaping the Future of Infrastructure.pdfCheryl Hung
Keynote at DIGIT West Expo, Glasgow on 29 May 2024.
Cheryl Hung, ochery.com
Sr Director, Infrastructure Ecosystem, Arm.
The key trends across hardware, cloud and open-source; exploring how these areas are likely to mature and develop over the short and long-term, and then considering how organisations can position themselves to adapt and thrive.
Builder.ai Founder Sachin Dev Duggal's Strategic Approach to Create an Innova...Ramesh Iyer
In today's fast-changing business world, Companies that adapt and embrace new ideas often need help to keep up with the competition. However, fostering a culture of innovation takes much work. It takes vision, leadership and willingness to take risks in the right proportion. Sachin Dev Duggal, co-founder of Builder.ai, has perfected the art of this balance, creating a company culture where creativity and growth are nurtured at each stage.
Slack (or Teams) Automation for Bonterra Impact Management (fka Social Soluti...Jeffrey Haguewood
Sidekick Solutions uses Bonterra Impact Management (fka Social Solutions Apricot) and automation solutions to integrate data for business workflows.
We believe integration and automation are essential to user experience and the promise of efficient work through technology. Automation is the critical ingredient to realizing that full vision. We develop integration products and services for Bonterra Case Management software to support the deployment of automations for a variety of use cases.
This video focuses on the notifications, alerts, and approval requests using Slack for Bonterra Impact Management. The solutions covered in this webinar can also be deployed for Microsoft Teams.
Interested in deploying notification automations for Bonterra Impact Management? Contact us at sales@sidekicksolutionsllc.com to discuss next steps.
Smart TV Buyer Insights Survey 2024 by 91mobiles.pdf91mobiles
91mobiles recently conducted a Smart TV Buyer Insights Survey in which we asked over 3,000 respondents about the TV they own, aspects they look at on a new TV, and their TV buying preferences.
GDG Cloud Southlake #33: Boule & Rebala: Effective AppSec in SDLC using Deplo...James Anderson
Effective Application Security in Software Delivery lifecycle using Deployment Firewall and DBOM
The modern software delivery process (or the CI/CD process) includes many tools, distributed teams, open-source code, and cloud platforms. Constant focus on speed to release software to market, along with the traditional slow and manual security checks has caused gaps in continuous security as an important piece in the software supply chain. Today organizations feel more susceptible to external and internal cyber threats due to the vast attack surface in their applications supply chain and the lack of end-to-end governance and risk management.
The software team must secure its software delivery process to avoid vulnerability and security breaches. This needs to be achieved with existing tool chains and without extensive rework of the delivery processes. This talk will present strategies and techniques for providing visibility into the true risk of the existing vulnerabilities, preventing the introduction of security issues in the software, resolving vulnerabilities in production environments quickly, and capturing the deployment bill of materials (DBOM).
Speakers:
Bob Boule
Robert Boule is a technology enthusiast with PASSION for technology and making things work along with a knack for helping others understand how things work. He comes with around 20 years of solution engineering experience in application security, software continuous delivery, and SaaS platforms. He is known for his dynamic presentations in CI/CD and application security integrated in software delivery lifecycle.
Gopinath Rebala
Gopinath Rebala is the CTO of OpsMx, where he has overall responsibility for the machine learning and data processing architectures for Secure Software Delivery. Gopi also has a strong connection with our customers, leading design and architecture for strategic implementations. Gopi is a frequent speaker and well-known leader in continuous delivery and integrating security into software delivery.
1. Laboratory Notebook
FITT
– Fostering Interregional Exchange in ICT Technology Transfer –
www.FITT-for-Innovation.eu
Except where otherwise noted, this work is licensed under a Creative Commons Attribution 3.0 License.
2. Laboratory notebook in general
The laboratory notebook is an essential working tool for the researcher. It is
used for documenting and dating any experiments, work, research results and
original ideas.
In general, it is an important source for:
• understanding how the experiments were conducted
• understanding how the conclusions were formed
• understanding how the results were deduced
The laboratory notebook establishes the precedence of results or inventions
from an intellectual property standpoint. It therefore constitutes evidence in the
event of disputes relating to scientific publications or patent applications in the
European Union and United States ("first to file" for EU & "first to invent" for
USA).
2 | April 2011 Laboratory Notebook
3. Laboratory notebook in practice:
What is laboratory notebook?
There are two hardware versions available:
• Paper Laboratory Notebook (PLN)
• Electronic Laboratory Notebook (ELN)
Historically the PLN medium has been used and employed by researcher from
the beginning. As a matter, codex from Archimedes (287BC – 212BC) and
Leonardo da Vinci (April 15, 1452 – May 2, 1519) have been found, retracing
their experiments.
Only recently, in the 1950s, research institutions and universities obliged and
regulated the usage of the PLN since a properly kept laboratory notebook can
be used in proving a company or university's right to obtain a U.S. patent.
Since the development of IT sector for 1990s and more recently during early
2000s the interest grew-up with the first worldwide Laboratory Informatics
forum(*)
(*) http://www.labinformaticsforum.com/
3 | April 2011 Laboratory Notebook
4. Laboratory notebook in practice: What to
record in both ELN and PLN?
• Title of the experiment in process and date • Every new working hypothesis
of execution
• Advance in a research
• Precise description of handling, as one
• Batch number of used material or products
goes along the execution, even if they did
not reach. • References of used methods and devices
• List of measurements • Partners participation
• Noticeable facts or observations (good & • Working discussions
bad)
• Copy of electronically stored data, with
• Interpretation and comments about the identification and localisation of the files.
obtained results
• Review of the results, ideas of handling to
improve and complete the results
4 | April 2011 Laboratory Notebook
6. Laboratory notebook in practice:
What is Paper Laboratory Notebook?
Sewed notebook, without mobile sheet.
• bound notebook and numbered pages
One cover page
• Research Unit, Name of the project, Name and signature of the user(s), Name and
signature of the manager, Number of the notebook
Table of contents (first sheets)
Pages to fill in
• Footer space reserved for signatures
Description of the procedure before the table of contents
6 | April 2011 Laboratory Notebook
7. Paper Laboratory Notebook in practice:
How does it look like ?
• Cover page • Table of content • Page to fill in
7 | April 2011 Laboratory Notebook
8. Who?
Who can use the ‘PLN’?
• Every people who realize researches in a research unit.
• Ideally, one notebook per person, but can also be allocated to a project or an equipment.
• The notebook is the property of the laboratory. All information contained in the notebook is
confidential and is the property of the University.
Setting up the PLN in a research unit
• Responsibility of the unit director • Responsibility of the researcher
- Order the notebooks via the - Ensure the confidentiality of his
responsible person researches
- Define the notebook allocation rules - Follow the practical advices for the use
of the notebook
- Ensure the archiving
- Keep his notebook in an appropriate
place
8 | April 2011 Laboratory Notebook
9. Where and When?
This paper laboratory notebook established by the LIEU network was granted
by the Walloon Region and the European Union.
It was adopted simultaneously by all the French speaking universities in
Belgium in 2005.
The use of the notebook is mandatory within the framework of research
convention financed by the DGO6 (Service public de Wallonie - Direction
générale opérationnelle de l'Economie, de l'Emploi & de la Recherche)
9 | April 2011 Laboratory Notebook
10. Why to use the laboratory notebook
Scientifically: memory of the researcher and of the laboratory
• Prevent from reinventing the existing
• Time saving / Simplification of the work
- For the research of information
- For publications / reports / patents writing
- For experimentation reproduction
• Avoid the loss of information
- Loss of sheets
- Walkout of a researcher
10 | April 2011 Laboratory Notebook
11. Why to use the laboratory notebook
Juridical: results protection
• Mean to define the know-how of the laboratory at a given time
• Interest for contracts
- clearly identify the confidential information and the exact contribution of each
• Proof in case of litigation
- Demonstrate the originality of an idea
• Interest for patents
- Patent application can lean on these recorded data (on condition that they were not
publicized before the patent fill in)
11 | April 2011 Laboratory Notebook
12. Lessons Learned @ LIEU
A satisfaction survey was organized in 2009. Interesting lessons were
learned with this feedback from the users:
• There is a need for frequent awareness sessions:
- Other types than the LIEU notebook are still in use. Uniformity is not yet accomplished.
- Some labs do not use any notebook.
- Procedure of use is not always well understood and applied
• Interesting remarks about the design of the notebook that can be adapted for
the next printing.
- Spiral-bound notebook for easier manipulation (with an unanswerable spiral), margin reduction (for more place
for the content), A4+ format (to glue an A4 doc without the necessity of cutting it),…
• Too many labs criticize the price of the notebook
- Solutions are under investigation to reduce the costs.
12 | April 2011 Laboratory Notebook
13. Lessons Learned @ Tudor
The test was conducted following this agenda :
We can divide the test in four phases :
- Understanding Tudor specific needs
- Designing a paper prototype based on previously needs The complete PLN
test took 4 months
- Implementing and testing of the paper prototype
- Feedbacks from the implementation and testing
13 | April 2011 Laboratory Notebook
14. Lessons Learned @ Tudor
Modification for Tudor implementation:
• A4 + layout to past printed paper without cut/paste
• Witness (more flexibility: list unnecessary)
• 1 Lab notebook per person and per project
• Different format (number of page)
• Spiral-bound laboratory notebook for easier manipulation
• Merge research project name and title of research topic,
too confusing keep research project name only
• Signature of the page once completed (not at the end of
the day)
• Delete the team or project manager name (confusing)
To be defined (organization policy):
• Language
• Define the witness identity (function and status)
• Access and conservation rules (location, time ??? )
• Index (validity)
14 | April 2011 Laboratory Notebook
15. Pro’s & Cons
Pro’s
• Laboratory notebook is
- The memory of the researchers / the laboratory (traceability)
- An element for excellence and professionalism in the field of scientific research
- A key element in the technology transfer policy
- An essential tool for the process of protection for the research results (proof mean)
Cons
- The procedure of use in the lab must be clearly defined
- Sometimes it is considered as a too heavy addition of work
- Need for frequent awareness sessions by the TT officer
- It still happens that no notebook or other type of notebook are still in use: it can cause
problems in IP management.
15 | April 2011 Laboratory Notebook
17. What is Electronic Laboratory Notebook?
An electronic laboratory notebook (also known as ELN) is a software program designed
to replace paper laboratory notebooks. ELN in general are used by scientists and
technicians to document research, experiments and procedures performed in a
laboratory. An ELN is often maintained to be a legal document and may be used in a
court of law as evidence. Similar to an inventor's notebook, the lab notebook is also
often referred to in patent prosecution and intellectual property litigation(1)
However an ELN can be accepted as a legal proof in the USA for patent application
under certain conditions i.e. compliant with 830-1984 - IEEE Guide for Software
Requirements Specifications and the FDA General Principles of Software Validation;
Final Guidance for Industry and FDA Staff.
In European Union such certification does not yet exist and is not used since the patent
date validation is based of the filling date of the patent and not the invention date.
Nevertheless we should still be prudent considering the juridical validity of notes in the
ELN(2)
(1) http://en.wikipedia.org/wiki/Electronic_lab_notebook
(2) http://europa.eu/legislation_summaries/information_society/l24118_en.htm
17 | April 2011 Laboratory Notebook
18. How does it look like ?
Is there different type of ELN ?
When it was first developed at the beginning of 2000s’ two types of ELN appeared :
specific and cross-disciplinary ELN
• Specific ELN are those made for one department with specific needs related to its
research subjects e.g. microbiology tailor made ELN
• Cross disciplinary ELN are developed for the whole company and its domain e.g.
physics & chemistry & biology etc…
Nowadays most of ELN products are modular. You will find specific tools made for your
original needs. Then you can extended the software possibilities thanks to modules.
What do you pay?
There are two models:
• General software (deployed on internal servers) with a Licence + annual fee for
maintenance
• Cloud solution with a monthly rate per user
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19. Electronic Laboratory Notebook in practice:
Which solutions ? (non exchaustive list)
The main ELN on the market are :
• Accelrys : Symyx Notebook 6.6 ELN http://accelrys.com/
• Cambridgesoft : E-notebook ultra 12.0 suite http://www.cambridgesoft.com/
• Cognium Systems : iPad http://www.ipadeln.com/
• Contur Software AB : iLabber http://www.ilabber.com/
• IDBS : E-workbook suite : http://www.idbs.com/ELN/
• Labage : Benchsys http://www.benchsys.com/
• Labtrack : ELN Version 4 http://www.labtrack.com/
• Labtronics : Nexxis ELN http://www.labtronics.com/
• Starlims : Electronic Notebook http://www.starlims.com/
• Velquest : SmartLab : http://www.velquest.com/
• Tracelite : Sibio : http://www.sibio.fr, ditributed in Benelux by BioXPR
• $
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20. What arguments in favor of the ELN:
Those companies advertise the following arguments in favor of their solutions :
• To handle complex processes
• User friendly interface
• Customizable interface
• Share the work (user rights possibilities)
• Research in the work
• Automate and standardize the research processes
• Intuitive tools
• Compatibility towards other scientific software
• To go paperless (Eliminate illegibility problems created by hard to read hand writing)
• Eliminate the waiting while someone else uses your paper notebook
• Eliminate paper storage and retrieval costs
• To insure conformity with organization rules
• Create templates easily
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21. Electronic Laboratory notebook in practice:
What to record in the laboratory notebook?
In addition to what is usually recorded in a laboratory notebook (see slide 4)
and based on the test realized during one month on a prototype version of
Labage software we can say that :
• Products description
• Machine description
• Media or any kind of data format
Can all be linked and saved in the ELN solution that we tried out. The
versioning system is automatic (date – name).
In addition different views of the software windows can be customized by the
user himself to better identify what data to record.
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22. Who?
Who can use the ‘ELN’?
• Every people who realize researches in a research unit.
• The ELN is the property of the laboratory. All information contained in the ELN is
confidential and encrypted in the software and is the property of the University.
Setting up the ELN in a research unit
- The setting up of the ELN has a strong and deep impact on the organisation structure. Not only
researcher behaviour must change but the whole processes in place might be impacted by the
software.
- As a matter of fact, features of such software are way above the PLN features and impact not only
the research unit and staff but can also impact the admin staff responsible for stock management.
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23. Where and When?
This ELN test was realized by the CRP Henri Tudor with the support of Labage
software, LIEU and the European Union.
We are currently evaluating other solution and will attend the 8th Forum on
Laboratory Informatics Conference for further research.
The use of Laboratory Notebook (electronic or paper) is not yet a requirement
but soon might be.
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24. Outcome
Plans for the future:
As in the 1980’s when the accountant world shift from the paper accounting toward the
electronic accounting, the scientific word is today moving toward the ELN.
There are two major trends which address two different markets:
• cloud solutions
• duo server/client based solutions
Small and medium research company can accommodate with the cloud solution
whereas big players will prefer to control and modify themselves their software.
Current PLN solution are still good but our recommendation is to move toward electronic
solution. However, juridical and legal validity should be validated by a patent attorney of
the European Patent Office.
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25. Pro & Cons between ELN and PLN
Criteria PLN ELN
Organization impact Easy Difficult
Job impact (learning curve) Middle High
Training Minimum Long
Use (writing) Manual Semi-automatic
Data research Slow Instantly
Storage (back-up) Risky Secured
Data availability Minimum Permanent & parallel
Follow-up (witness, manager) On the spot 24h/7d
Cost Less expensive short term Less expensive long term
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26. Suggested Reading
Link to code book
• LIEU
• Research result
• Invention
• Intellectual property
• Patent
Other
• Taylor, Keith (2006), "The status of electronic laboratory notebooks for chemistry and
biology", Current Opinion in Drug Discovery & Development 9 (3): 348–353
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