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Green Data for Green AI
Is new European Health Data Space 
Regulation timely?
Dr. Dimitris Kalogeropoulos,
Independent Advisor, World Bank, WHO, European Commission
World AI Show
Keynote
July 13th 2022
Agenda
 Establish a baseline for AI in health
 Identify shortfalls toward impact investing in AI
 Suggest a way forward to scale and sustain value in AI  
Baseline
2022 Report 
Sanford Institute
for Human‐
Centered AI
 Disconcerting gap between corporate recognition of AI risks 
and efforts to mitigate
 Investment is off the hook
 Ethics is centre‐stage 
 Data are a problem
 Carbon footprint is an issue
 Diversity is an issue 
 AI vision has reached a plateau
 Reasoning is still a frontier of AI 
Baseline
Council of Europe
Steering 
Committee for 
Human Rights in 
Biomedicine & 
Health
 AI deployment in care remains nascent 
 Clinical efficacy has been established for few apps compared to 
reported research activity  
 Performance generalization from trials to clinical practice is 
largely unproven
Begs the question: What are we doing wrong?
Scaling
Spreading
Sustaining
data
recycling
We don’t 
recycle !
design impact
clinical 
economy 
society
3S policies
 Data recycling is necessary for 3S policies
 To make the transition from AI design to impact
 To unlock value in AI and innovation
 To implement green health policies  
Sustainability  
Impact Ratio 
(SIR) = 
Health Impact
Environmental 
Impact (cost) 
 Currently experiencing a vast digital acceleration: 
(1) new diagnostics (2) big data (3) Covid‐19 (4) wearables
 Hope is AI will help produce value
 Every new AI design = new data set design
 Data are farmed in big data pools (cost, emissions) – data of 
unknown origins in quality
predictor value ‐ ground truth performance, cohort bias or errors
 This data is completely removed from the clinical reality
 Vicious circle: Scaling not possible -> health impact - value
remains unproven -> adverse impacts – opportunity costs
silently proliferate
 Finally, AI is not an innovation without the delivery service –
instead is exploited to deliver a new way of doing things
Restore SIR
• A Green-AI-for-Green-
Health-and-Sustainable-
Innovation-Policy is long
overdue
• Seek to restore the balance in
the innovation ecosystem with
data recycling, and to enable
health impact scaling and
digital acceleration spillovers
• Recycled data must
adhere to strict reuse
standards (ex-
interoperability) and will
therefore be reliable and
accurate, further reducing
carbon emissions: with
higher AI value,
efficiencies and better
productivity
Reduce 
carbon, not 
add !
Healthcare already has significant contribution to the 
global carbon footprint, that is before we consider
 Data overproduction related emissions
 The AI production efficiency impact on the climate or 
data farming 
 The low AI‐exploiting innovation SIR
Specifically 
Combat these 
Carbon Sources
Compromised 
value in core  
ecosystem
innovation 
farms
Industry‐led 
designs and 
outcomes
Over- or
Under
Diagnosis
Low or
no-value
Care
Over-
medicali
sation
AMR
Downstream
-focused
policies
Treatments with
poor health
outcomes - high
climate impact
Patient-in-
wrong-cohort
decisions
High risk-cost,
low benefit
treatments
Overuse of
measurement
technology
Reduction in
efficiency of
health systems
Patient care pathway 
fragments 
Big data
Siloed care and data
Passive Core
HCS Over-
or Under
Use
Introvert 
Implosive 
Remote
triaging AI
Radiology image
screening AI
Carbon 
Reducing
Innovation
Helix
Data 
ecosystem 
Restoration
ecosystem 
restoration
SDGs,
3 Billion targets,
digital diplomacy
Value-
based
Care
Quaternary
Prevention
Improved,
faster, more
relevant clinical
trials
Upstream and
prevention
focused policies
Digital Designs
for high-value
care pathways
Re-admission
prevention
virtual care
Patient
engagement &
participation
Precision
Diagnosis
Data 
Recycling
Green 
Data
Loosely, seamlessly  
connected Innovation
Remote
care
Shared Results –
Common Data Sources
Active Core
Extrovert 
Scalable
Precision
Treatment
Reframe the 
conversation
Stats, Records, 
EMRs, Pseudo‐
EHRs
HL7 interop
Reframe 
Policies & 
Regulatory 
Solutions
Bridge the 
Scalability Gap
ex‐interoperability 
problem
Objectives
 Intervene in High Carbon Emission Areas to produce and recycle 
green data and fuel Good AI
 Introduce Digital Asset Passports to meet recycling standards
 Mandate reporting on current practice emissions 
e.g. readmissions per disease per value pathway
 Reduce carbon emissions in current practices adopting green 
health policies and enabling recycled data
 Reduce amount of data generated with computers and medical 
equipment
 Introduce circular economy models in innovation
 Establish new digitally enabled green care models
e.g. quaternary prevention
 Reduce data farming
Greener 
Health 
Approach
New Policy
Paradigms
Agile Data
Ecosystem
Restoration
Public-
Social-
Private
Partnership
Green
Digital
Accelerators
Enable 
3C AI
Mass Green
acceleration
Greener
Health
Green Digital Health
Meta-Policy weaves
together directionality
components:
1. Governance: Social-
Data-Clinical-Economic
2. Data Tech: Ecosystem
Decentralisation-
Semantic Federation
3. Telehealth: Access-
Scale-Engage-
Participate
4. Agile migration
3C AI
Collaborative 
Connected  
Collective
Collaborating
Agents
Autonomous Intelligence 
CollaborativeAI
2023‐2030 
Single ‐ curated
ecosystem 
Multiple –
Autonomous 
Agents in recycled‐
data‐enabled 
ecosystem
Artificial General
Intelligence 2035‐
Seamless AI
2030‐2035
Machine Learning
Knowledge‐Based 
Systems
course correct
now
Is EU 
Regulation on 
Health Data 
Spaces timely? 
In a Nutshell 
European Health Parliament Initiative 7th Edition, July 2022 –
Creating a resilient European Health Union
Lacks a digital 
ecosystem NEXUS
‐
Same as with EHDS 
Regulation
Collaboration 
between policy 
makers and public 
health needed
 INNOVATION 6 ‐ Realize Green, Digital, 
Just Transition: Prioritize innovations that 
catalyse the transition to a green, digital 
and just economy for sustainable 
development 
 IMPACT INITIATIVE 2.6 – Initiate the 
design and development of standards and 
pilot testing for digital product passports
that track a product’s climate, 
environmental, and social impacts 
throughout the value chain
 IMPACT INITIATIVE 3.3 – Decentralised 
Financing
Coalition for Digital 
Environmental 
Sustainability (CODES)
UN CODES
Action Plan for 
a Sustainable 
Digital Planet ‐
2022
No mention of a 
digital acceleration 
ecosystem
EU 2022 
Twining Green 
and Digital
Strategic 
Foresight Report
 Mutual reinforcement of the green and the digital transitions
 Adoption of circular economy models in all sectors
 Digital technologies catalyse the green transition
 Just [inclusive] transition is crucial for widespread acceptance 
of green digital solutions
 Social awareness, governance and innovation participation 
could avoid rebound effects, such as increased consumption as 
a result of efficiency gains and cost savings
 Green digital diplomacy
 Ensure policy cohesion
No mention of a 
digital acceleration 
ecosystem
Data Principles 
for Recycling
Value
Trust
Social 
Contract
Equity
The full value of data
materializes when
systems enable the
use and reuse of data
for different purposes
All share equitably
in the benefits of
data when
investments and
regulations create a
level playing field
A trust
environment is
created when the
rights and
interests that all
stakeholders have
in data are
safeguarded
Social Contract for Data - World Bank Flagship Report Data for Better Lives
Recycling 
enablers
Precision 
Med/ 
Outcome 
Innovation
Observation 
Innovation: 
Telehealth, 
Systems Med
Health or 
Disease 
State
Diagnosis
Shared 
Goal
Treatment 
Innovation 
(precision Tx)
1. Digital ID
2. Privacy protection
3. Agent (care) prevalence
4. Cybersecurity
5. Clinical prevalence
6. Collective agency
7. DLT for value supply
8. Digital Existence Graphs
9. Collaborative care
10. Integrated care
11. 3C AI
12. Shared care
13. Seamless care
1
2
3
13
Roadmap to
Data Recycling 
Recycled Data Core
Marker patterns for 
diagnosis, prognosis or 
prevention – mapped to 
standardised core
Wider systems medicine or 
heuristic/ algorithmic 
model
Precision medicine service 
models (4P)
Outcome
Observation
Health or 
Disease 
State
Diagnosis
Treatment
Agile Migration
High Carbon Practice Area:
Prognosis and precision
management of acute
ischaemic stroke with
classification of sub-type
(TOAST). Model feature value
tested using EHR data and ML
“mining”.
Action plan for 
Green Health
data
recycling
adopt green
health
approach
restore
healthcare
environment
restore
innovation
ecosystem
adopt 3S
policies
for value
design for
equity
inclusion
impact
Integrated
telehealth
Digital
Acceleration
platforms
3S action
Impact
investing
aims
actions
Please recycle 
your data

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