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November
Issue 04
2023
Maryland
Oncology
Hematology
Providing Advanced Cancer Care Through
Compassion and Care
Dr. Mohit Narang
US Oncology Research
Maryland Oncology
Hematology
5
5
to Watch in 2023
Hematology
Most
Trusted
Solution Providers
+
A Critical Analysis
The Role of
Hematology in
Modern Medicine
Pediatric Hematology
Addressing Unique
Challenges in Young
Patients
Ensuring an invigorated and
sustainable future for hematology and,
in particular, non-malignant hematology,
is key strategic priorityfor the society.
Ensuring an invigorated and
sustainable future for hematology and,
in particular, non-malignant hematology,
is key strategic priorityfor the society.
Martin S. Tallman
The Three
Pillars -
Precision,
Progress,
Promise
Editor’s
Note
In the dynamic world of hematology, we’re diving into
something big. Our latest edition of Insights Care is all
about breaking new ground, and we’re focusing on
what makes it happen in hematology – Precision, Progress,
and Promise.
Precision in hematology is like personalizing your playlist,
but for healthcare. It’s about tailoring the approach to each
patient, using advanced tools and treatments that fit like a
glove. And who’s leading the charge? Meet the innovators –
the companies and individuals making precision in
hematology a reality.
Now, let’s talk Progress. This isn’t just about moving
forward; it’s about taking giant leaps. We’re exploring the
cool stuff happening in labs and clinics – from
understanding hematological disorders better to trying out
new therapies. And who’s behind these strides? The
companies and experts at the forefront of hematology,
making waves in progress.
And then there’s Promise. It’s not just a word; it’s a
commitment to a brighter tomorrow. We’re showcasing the
latest technologies and approaches that have the potential to
change the game in hematology. Who’s turning this promise
into reality? The companies and visionaries who are
shaping the future of hematology care.
As you flip through this edition, 5 Most Trusted
Hematology Solution Providers to Watch in 2023, think
about it like you’re on a journey – not a grand quest, but an
honest exploration of what’s happening in hematology
today. These stories aren’t just about cool science; they’re
about real people, real progress, and a real promise for
better health. Insights Care proudly presents this deep dive
into Breaking New Ground, inviting you to join the ride, get
to know the innovators, and discover the human side of
hematology.
Hope you have an interesting read!
Pearl Shaw
Managing Editor
Maryland
Oncology
Hematology
Providing Advanced Cancer Care Through
Compassion and Care
08
A Critical Analysis
Pediatric Hematology
Xcene
Research
Changing the Sub-Saharan Africa
Landscape of Clinical Research
The Role of Hematology in
Modern Medicine
Addressing Unique Challenges
in Young Patients
Articles
Pro le
18
14
22
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November, 2023
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Managing Editor
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Brief
Featuring
Person
Company
MediSix Therapeutics is developing game-
changing T-cell therapies by leveraging an array
of proprietary technologies that improve and
expand T-cell function.
SEHH is dedicated to advancing Hematology in
Spain, fostering excellence, transparency, patient-
centric care, and global leadership in healthcare.
Maryland Oncology Hematology is dedicated to
providing the most advanced cancer care available
anywhere in an atmosphere of caring compassion.
MediSix Therapeutics
medisixtx.com
Andrew Bruce
CEO
Dr. Mohit Narang
MD
Jorge Sanchez
MD
Maryland Oncology
Hematology
marylandoncology.com
Sociedad Española de
Hematología y
Hemoterapia
sehh.es
Sysmex Corporation is a global leader in healthcare,
specializing in innovative diagnostic solutions and
cutting-edge medical technologies.
Hisashi Ietsugu
CEO
Sysmex
sysmex.co.jp
Xcene Research pioneers clinical research,
specializing in Sub-Saharan Africa, offering end-to-
end services with trust, quality, and efficiency.
Adebukunola Telufusi
Executive Director
Xcene Research
xceneresearch.com
5
5
to Watch in 2023
Hematology
Most
Trusted
Solution Providers
+
Maryland
Oncology
Hematology
Providing Advanced Cancer Care Through Compassion and Care
We’re a part of the
US Oncology network,
which gives us access
to additional resources.
We’re able to reach out
to other physicians
to get the best answers
for our patients.
Cover
Story
Dr. Mohit Narang
US Oncology Research
Maryland Oncology Hematology
ancer is a devastating disease that affects millions
Cof people worldwide. Cancer care from diagnosis to
treatment and beyond requires a multidisciplinary
team of healthcare professionals who work together to
provide personalized care, support, and guidance
throughout the cancer journey. Providing advanced cancer
care with compassion is essential for not only treating the
physical symptoms but also addressing the emotional and
psychological aspects of cancer.
Maryland Oncology Hematology is known for being
present and willing to support each person who experiences
a variety of emotions associated with cancer, or blood
disorder/disease. Its dedicated physicians, nurses, and staff
guide the diagnosed through several treatment options,
tailoring services to unique, individual needs. As the
treatment begins, factors like—relationships with others,
management of side effects from treatment, nutrition, and
diet become an important part of treatment. And the
physicians and staff center are dedicated to helping with so
that the patients can navigate through this challenging time
with ease.
Four major types of treatments for cancer could be expected
at Maryland Oncology Hematology:
Ÿ Biologic/targeted therapies: A newer type of cancer
treatment that can more precisely attack cancer cells
using a combination of drugs and other substances.
These therapies work differently than traditional
chemotherapy drugs.
Ÿ Chemotherapy: This treatment uses anti-cancer drugs
to treat cancer by stopping or slowing the growth of
cancer cells.
Ÿ Radiation Therapy: Advanced radiotherapy delivery
methods are used to target and treat a wide range of
malignancies. This treatment is designed to target and
destroy cancerous cells by preventing them from
growing or dividing while minimizing adverse effects
on nearby healthy organs and tissues.
Ÿ Surgery: For some cancers, surgery may be used to
remove all or part of the cancer to prevent spread.
The clinic today is the largest independent Medical
Oncology and Hematology group in Maryland with 40
physicians practicing in fifteen locations across central
Maryland. It is united in healing with the US Oncology
Network, one of the nation’s largest community-based
cancer treatment and research networks focused on
advancing cancer care in America. This network has over
1000 physicians and 10,000 cancer professionals
nationwide.
When Dr. Mohit Narang, M.D, met other physicians there,
he immediately knew that he has found his second family
who were just as driven in providing excellent patient care,
as he was.
Let’s dive in to know about Maryland Oncology
Hematology’s operations in providing the most advanced
care available anywhere in an atmosphere of caring and
compassion.
Source of Inspiration
Maryland Oncology Hematology was started in the late 90s
by Jon Minford, MD. It is a community-based practice
taking care of patients locally. The center had five full-time
oncologists at the time. Maryland Oncology Hematology’s
one of the goals is to provide cutting-edge treatment and
research to patients in its community, both for benign
hematology and oncology.
Our guiding principle is the
patient comes irst. Patient
care should be held to the
highest standard. If there’s
the care we cannot provide,
we try to ind that care for
that patient in the best place
possible. We consider ourselves
the quarterback for the patient.
5 Most Trusted Hematology Solution Providers to Watch in 2023
Thus, in the past decade, the center has grown from five
physicians to 52 physicians, with 12 offices in Maryland.
Journey So Far
After finishing a fellowship at Michigan State University,
Dr. Mohit Narang moved to Arkansas and opened the first
cancer center in Batesville,before starting a group
purchasing organization for more than 100 oncologists.
From there, he moved to Maryland, where he’s been
practicing medicine ever since.
Before moving, Dr. Narang had a choice between coming to
Maryland, and moving to Boston and joining a practice
there. He and his family chose Maryland because they
enjoyed the lifestyle here, and they were happy with the
schools, but the practice was also a major factor. When he
met the other physicians there, Dr. Narang knew they were
driven by the patients. The goal of the practice was to
provide excellent patient care first, and that was a priority to
him
“The practice does feel like a family to me. I like to say I
have two marriages—my wife and this practice,” says Dr.
Narang.
Dr. Narang has been a top Baltimore physician in colon
cancer, prostate cancer, and hematology for the past four
years in a row. He has published more than a hundred
articles and has more than 70 active studies going on his
sites Dr. Narang is also a member of the American Society
of Hematology, the American Society of Clinical Oncology,
and the European Society of Medical Oncology, the
International Extranodal study group, Advisor CONNECT
Myeloma study group.
Core Values
Maryland Oncology Hematology’s guiding principle is the
patient comes first. Patient care should be held to the
highest standard.
“If there’s the care we cannot provide, we try to find that
care for that patient in the best place possible. We consider
ourselves the quarterback for the patient,” adds Dr. Narang.
Compassionate Care Services
For Maryland Oncology Hematology, patient comfort
comes first.
“Our patients aren’t a number, they’re an individual. We
provide care in a timely, punctual manner, for both cancer
patients and our patients with benign hematological
conditions,” says Dr. Narang.
“We can open many research studies in less than two
weeks. If a patient comes to us with a rare form of cancer or
has a rare mutation, we can start the research treatments in
no time. Elsewhere, they may have to travel across the
country, or even internationally. We can provide studies in
the office, close to home, which is a huge advantage for our
patients.”
He continues, “Although we are a cancer center, we also do
infusions for benign conditions for gastroenterology,
rheumatology, Neurology and Cardiology. So we’re a
composite of both an infusion center and a cancer center.”
Cutting-Edge Treatments
It’s important for the physicians at Maryland Oncology
Hematology, to stay up to date on cutting edge treatments.
“We’re a part of the US Oncology network, which gives us
access to additional resources,” said Dr. Narang “We’re
able to reach out to other physicians to get the best answers
for our patients.” As a community-based practice focused
on providing top-level care to patients locally, it’s important
Our patients aren’t a number,
they’re an individual. We provide
care in a timely, punctual manner,
for both cancer patients and
our patients with benign
hematological conditions.
for the clinic to stay updated and grow with the research
and advancements, so that the patients are offered the best
care that they need.
Words of Wisdom
For the budding enthusiasts who aim to venture into the
healthcare sector, Dr. Narang suggests, “If you are planning
to venture into healthcare, you need to love this field. Please
do not join for commercial reasons. I think the key thing to
remember is healthcare is more than a vocation. You’re
with your patients through a crucial part of their life. You’re
with their families. That’s what’s important, and that needs
to be a driving factor.”
Looking Ahead
Looking ahead to 2023, Maryland Oncology Hematology’s
goal is to grow, especially geographically.
“We are also opening phase one study sites, which are not
always available to patients who cannot travel to a
university to receive those treatments. We are trying to open
CAR-T sites. We want to make care more accessible and
affordable where our patients already live.”
We can open many research
studies in less than two weeks.
So if a patient with rare cancer
or has a rare mutation, we can
start the research treatments
in no time. Elsewhere, they may
have to travel across the country,
or even internationally. We can
provide studies in the of ice,
close to home, which is a huge
advantage for our patients.
ematology, the branch of medicine that focuses
Hon studying blood and blood-related disorders,
plays a pivotal role in modern healthcare. As
medical science advances, our understanding of hematology
becomes increasingly critical in diagnosing, treating, and
preventing various diseases.
In this article let’s delve into the multifaceted aspects of
hematology, examining its significance, recent
advancements, and the evolving landscape of its
applications in contemporary medicine.
Understanding Hematology
At its core, hematology encompasses the study of blood and
its components, including red and white blood cells,
platelets, and plasma. The discipline goes beyond
identification and classification; it explores the intricate
mechanisms governing blood function and its role in
maintaining overall health. Hematologists, armed with
advanced diagnostic tools, delve into the microscopic realm
to unravel the complexities of blood-related disorders,
ranging from anemia to leukemia.
Hematology in Disease Detection
One of the primary contributions of hematology to modern
medicine lies in its diagnostic capabilities. Blood tests have
become indispensable tools for identifying many
conditions, from routine check-ups to critical illnesses.
Hematological factors such as complete blood count (CBC)
and blood smears provide valuable insights into an
individual’s overall health.
For instance, red blood cell count alterations, hemoglobin
levels, or platelet counts can be early indicators of various
diseases. A low red blood cell count may signal anemia,
while abnormal white blood cells may suggest infections or
autoimmune disorders. By scrutinizing these microscopic
elements, hematologists can diagnose and initiate treatment
promptly, often preventing the progression of diseases to
advanced stages.
The Role of
Hematology
Modern Medicine
in
14 | Nov 2023 www.insightscare.com
A Critical
Analysis
15 | Nov 2023 www.insightscare.com
Cancer Diagnosis and Monitoring
Hematology emerges as a frontline player in the battle
against cancer. Leukemia, a cancer affecting the blood and
bone marrow, is a critical factor in oncology.Through
sophisticated techniques such as flow cytometry and
molecular testing, hematologists can identify specific
markers associated with various types of leukemia,
allowing for precise diagnosis and tailored treatment
strategies.
Moreover, hematology plays a crucial role in monitoring
cancer patients undergoing treatment. Regular blood tests
enable healthcare providers to assess the effectiveness of
therapies, adjust treatment plans, and manage potential side
effects. This dynamic monitoring is instrumental in
improving patient outcomes and enhancing the overall
quality of cancer care.
Advancements in Molecular Hematology
Advancements in molecular biology have significantly
reshaped the landscape of hematology. The advent of
genetic testing and molecular profiling has revolutionized
our understanding of blood disorders at the molecular level.
Inherited conditions such as hemophilia and thalassemia
can now be diagnosed with greater precision, enabling
healthcare professionals to offer targeted therapies and
personalized treatment plans.
Molecular hematology also extends its reach to the realm of
hematologic malignancies. Identifying genetic mutations
associated with conditions like myelodysplastic syndromes
(MDS) and lymphomas has paved the way for novel
therapeutic approaches, including targeted therapies and
immunotherapies. This precision medicine approach
positively impacts outcomes and reduces side effects
compared to conventional treatments.
Blood Transfusion Medicine
Hematology’s influence extends to the critical domain of
blood transfusion medicine, ensuring the safety and efficacy
of blood transfusions. Blood transfusions are integral in
various medical interventions, including surgeries, trauma
care, and treatments for certain medical conditions.
Working in tandem with blood banks, hematologists
meticulously screen donated blood for infectious agents and
compatibility, minimizing the risk of transfusion-related
complications.
In addition to traditional blood transfusions, advancements
in hematology have led to the development of therapies
such as stem cell transplantation. This innovative approach
holds immense potential for treating various blood
disorders, including leukemia and lymphoma.
Hematopoietic stem cells, capable of differentiating into
different blood cell types, offer a lifeline for patients facing
otherwise limited treatment options.
Challenges and Future Directions
While hematology continues to make significant strides,
challenges persist. Disorders such as sickle cell anemia and
rare blood cancers present ongoing hurdles that demand
focused research efforts and innovative therapeutic
interventions. The field is also facing the task of adapting to
the changing healthcare environment, including integrating
artificial intelligence and machine learning in diagnostics
and treatment decision-making.
As we look to the future, collaborations between
hematologists, geneticists, and other specialists become
increasingly vital. The interdisciplinary approach will
facilitate a more comprehensive understanding of blood
disorders and foster the development of targeted therapies.
Moreover, ongoing research in stem cell biology and
regenerative medicine holds the promise of groundbreaking
treatments that could revolutionize the management of
various hematologic conditions.
Conclusion
In conclusion, hematology is a cornerstone in modern
medicine, driving advancements in diagnostics, treatment
strategies, and our overall understanding of blood-related
disorders. From cancer diagnosis to blood transfusion
safety, the contributions of hematologists are invaluable in
enhancing patient outcomes and shaping the healthcare
landscape. As technology progresses, hematology’s role
will undoubtedly expand, reaffirming its status as a critical
player in the ongoing pursuit of medical excellence.
Pearl Shaw
16 | Nov 2023 www.insightscare.com
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Xcene Research
Changing the Sub-Saharan Africa Landscape of Clinical Research
The process of drug development is generally a
complex and highly regulated area of the healthcare
industry. Therefore, it is important to work with
someone who has a thorough understanding of the process,
combined with a depth of therapeutic expertise to get your
new products and treatments out into the market.
Xcene Research is one such contract research organization
(CRO), with a focus on providing high-quality services,
with a special focus on emerging markets across Sub-
Saharan Africa. The company offers comprehensive support
to pharmaceutical, biotechnology, and medical device
companies, as well as academic research institutions, across
the region.
Xcene Research understands the unique challenges
associated with clinical research in Africa, and thus, it is
dedicated to overcoming them. By leveraging its deep
knowledge of the local regulatory landscape and cultural
sensitivities, the company helps its clients navigate the
clinical development process smoothly and efficiently.
The company aligns its operations with the core value of
trust. This is reflected through its standards of on-time
performance, delivery of uncompromising quality, complete
visibility into project status and optimal communication to
manage client goals. As a result, it has become a trusted
partner for clinical research in Africa and is making a
significant impact in the industry.
In an interview with Insights Care, Adebukunola Telufusi,
the Executive Director explains how through its work, the
company is helping to advance medical knowledge,
improve access to high-quality medical care, and enhance
the healthcare landscape in Sub-Saharan Africa and beyond.
Following are the excerpts from the interview:
Please brief our audience about the company. What led
to its inception?
Xcene Research is an indigenous African Contract Research
Organization (CRO) bringing clinical trials to a more
diverse population in Sub-Saharan Africa. As a leading
CRO, we provide full-service support to pharmaceutical,
biotechnology, and medical device companies, as well as
academic research institutions across Sub- Saharan Africa.
With a diverse population and bearing the greatest disease
burden in the world, the African continent can provide
many of the conditions optimal for carrying out clinical
trials. Xcene Research sees the opportunity to breach the
gap in healthcare and is bringing more clinical trials to an
expansive genetically diverse population and in turn,
improving interventions for Africans.
Can you elaborate upon the core values on which the
company is built and what is its mission?
Xcene's core values revolve around five distinct principles
guiding all our processes, systems, and culture. These are
Ethics, Innovation, Quality, Progress, and Partnership. We
Xcene Research is an
indigenous African Contract
Research Organiza on (CRO)
bringing clinical trials to a more
diverse popula on in Sub-Saharan
Africa. As a leading CRO, we
provide full-service support to
pharmaceu cal, biotechnology, and
medical device companies, as well as
academic research ins tu ons
across Sub- Saharan Africa.
5 Most Trusted Hematology Solu on Providers to Watch in 2023
18 | Nov 2023 www.insightscare.com
Adebukunola Telufusi started as the
Founder of Xcene Research and has 15
years of experience in enabling
community development and social
development goals in Africa. Her
career spans working with top-ten
global pharmaceu cal companies and
CROs as a consultant and project
manager with experience in regulatory
requirements regarding the conduct of
clinical trials in Sub-Sahara Africa and
the US. Her therapeu c experience
spans from Phase I through Phase IV
trials in Hematology, pediatrics,
cardiovascular disease, CNS, diabetes,
oncology, neurology, medical devices,
vaccines, and women's health.
Adebukunola put together a team that
is the core founda on of Xcene
th
Research. Currently, in its 8 year, the
company has grown exponen ally, and
studies have been brought to Africa
with a diversity-first mindset. "Xcene
focuses on the following 21
therapeu c areas including –
Hematology, Cardiovascular,
Nephrology, Pediatrics, Oncology,
Infec ous disease and Sickle cell
disease which is our biggest por olio.
Our Sub-Sahara footprints across 6
ac ve sites including Nigeria, Ghana,
Kenya, Uganda, Tanzania, and Kenya,"
says Adebukunola.
Buki as she is fondly called and Xcene
are intertwined, and both have had a
fulfilling journey to bring in
medica ons and grant pa ents access
to healthcare. Innova on and
collabora on are the company's
watchwords with the aim of becoming
an impac ul healthcare solu on
provider to Africa.
Adebukunola Telufusi in Brief
Adebukunola Telufusi
Execu ve Director
Xcene Research
19 | Nov 2023 www.insightscare.com
are dedicated to building strategic partnerships across the
globe as we look to improve the health system across sub-
Saharan Africa and when it comes to global health, we
believe that innovation and collaboration are the keys to
progress.
Our mission is to be a catalyst for accelerated access to life-
saving treatments which speaks to our dedication to
building strategic partnerships across the globe with the
highest standards of delivery as we look to improve global
health issues across Sub-Sahara Africa.
Tell us more about the services that make your company
stand out from the competition.
Xcene Research has extensive relationships with leading
pharmaceutical and biotechnological companies, regulators,
and medical centers as well as experienced investigators
across Sub-Sahara Africa, Europe and the USA. This gives
us unparalleled access to patients, patient data, and the
expertise and perspective of physicians who are leaders in
their field. Our clinical research professionals identify,
translate, and answer complex questions while working
with sponsors to advance the practice and the future of
medicine. All studies conducted by Xcene Research are in-
line with global regulations and ICH-GCP standards.
Key areas of our services cut across:
Site Startup, Clinical Trial Monitoring, Site Intelligence &
Activation, Site Training, Data Management, Project
Management, IRB Submission, Patient Recruitment,
Regulatory Development, Central Laboratory, Clinical
Supplies, Quality & Compliance, Medical & Safety
Management.
What is your opinion on healthcare providers' aligning
their offerings with newer technological developments,
especially when it comes to catering to the dynamic
needs of the healthcare space?
We consider technological developments and capabilities a
path to fundamentally transform healthcare systems and
these priorities will continue to evolve. It is pertinent to
align with new developments because the impact of
technological transformation will be felt across all aspects
of health care, enabling easier access to care, improving
quality, and decreasing the cost of care.
Consumers can connect quickly and conveniently with their
preferred provider. In addition to stronger patient
relationships, such innovations can also help improve
operational and financial efficiencies and bring health
systems' long-term strategies into reality.
What advice would you like to give to budding
entrepreneurs and enthusiasts aspiring to venture into
the healthcare niche?
Zeal, focus, be informed and be impact driven. It is
essential that aspiring budding entrepreneurs gain a good
understanding of what medical entrepreneurship implies
and equip themselves with the know-how and skills they
need to thrive in this environment.
Networking and meeting the right people can help expand
their network while reconciling social purpose and profit
should be considered in their business operations.
There is always room for improvement, so staying in the
know and bringing innovation to the table will propel them
on the path to success.
How do you envision scaling the company's services and
operations in 2023 and beyond?
We do foresee Xcene being the number one healthcare
provider in Africa. In the pipeline of services to extend our
offerings, is the Xcene Laboratory Diagnostics (XLD)
which would be launched in Q4 of 2023. It is one of its
kind to complement clinical trials sample analysis
conducted by Xcene research across sub-Sahara Africa and
will serve as a central Laboratory for clinical trials for other
CROs and healthcare institutions across Africa for analysis.
The Xcene Research Academy (XRA) to be launched in
Q3 of 2023 will further add capacity to bridge the gap in
clinical research and provide technical and industry
knowledge to Africa's next generation of researchers.
The Impact Africa Summit (IAS), which is a brainchild of
Xcene Research, was inaugurated in 2020 to build
sustainable capacity for clinical research through
partnerships in Africa. The summit has brought together
1500+ attendees, 7 Sub-Saharan Regulators, 50+ speakers
and 14 workshops, forums, and scientific symposiums.
We aim to continue to work on our processes and finetune
them to stand as the go-to CRO across Africa.
20 | Nov 2023 www.insightscare.com
Pediatric Hematology
Addressing Unique
Challenges
Young Patients
in
22 | Nov 2023 www.insightscare.com
ediatric hematology, the specialized branch of
Pmedicine focused on blood disorders in children,
presents a distinct set of challenges and
considerations. Understanding and managing blood-related
conditions in young patients require a nuanced approach
that factors in the unique aspects of pediatric physiology,
development, and emotional well-being.
In this article, we delve into the intricacies of pediatric
hematology, exploring the challenges healthcare
professionals face and the strides made in ensuring optimal
care for young patients.
Pediatric Blood Disorders
Blood disorders in children encompass a broad spectrum of
conditions, ranging from common ones like anemia to rare
genetic disorders such as hemophilia and thalassemia.
Diagnosing and treating these disorders in pediatric patients
require a specialized skill set, considering the physiological
differences between children and adults. Pediatric
hematologists, equipped with expertise in both hematology
and pediatrics, play a pivotal role in addressing these
unique challenges.
Diagnostic Dilemmas
Diagnosing blood disorders in children poses distinctive
challenges due to the variability in normal blood values at
different stages of development. For instance, a lower red
blood cell count in a child may not necessarily indicate
23 | Nov 2023 www.insightscare.com
anemia but could be within the normal range for their age.
Pediatric hematologists employ age-specific reference
ranges and carefully consider developmental factors to
accurately diagnose and differentiate between benign
variations and potential disorders.
Communication and Emotional Considerations
Caring for pediatric patients involves not only addressing
the physical aspects of their conditions but also navigating
the emotional and psychological impact on the child and
their family. Effective communication is paramount in
pediatric hematology, requiring healthcare professionals to
convey complex information in a manner that is age-
appropriate and sensitive to the child’s developmental stage.
Pediatric hematologists often collaborate with child life
specialists and psychologists to create a supportive
environment, easing the anxieties associated with medical
procedures and chronic illnesses. Building trust with young
patients and their families is essential for successful
management and adherence to treatment plans.
Unique Treatment Approaches
Treatment modalities in pediatric hematology must be
tailored to the specific needs of children, considering
factors such as growth, development, and potential long-
term effects. Medication dosages, for instance, need to be
carefully calculated based on a child’s weight and age.
Furthermore, the choice of treatment may be influenced by
the potential impact on the child’s quality of life, growth,
and development.
In the case of hematologic malignancies, pediatric oncology
and hematology collaborate closely to provide
comprehensive care. The treatment of childhood cancers
often involves multi-disciplinary teams, including surgeons,
radiation oncologists, and nurses, working together to
ensure the best possible outcomes for young patients.
Innovations in Pediatric Hematology
Advancements in pediatric hematology have significantly
improved the outlook for young patients facing blood
disorders. Precision medicine, with its focus on tailored
therapies based on genetic and molecular profiles, holds
promise for more effective and less invasive treatments.
Research in gene therapy and targeted therapies specifically
designed for pediatric blood disorders is underway, offering
hope for improved outcomes and reduced side effects.
Education and Advocacy
Addressing the unique challenges in pediatric hematology
extends beyond the clinic and hospital walls. Educational
initiatives aimed at parents, caregivers, and schools
contribute to early detection and effective management of
blood disorders in children. Increased awareness fosters a
supportive community that understands the specific needs
of pediatric patients and promotes a holistic approach to
their care.
Additionally, advocacy for pediatric hematology research
and funding is crucial for driving innovation and improving
the standard of care. By raising awareness at the policy
level, stakeholders can ensure that resources are allocated to
advance research, enhance diagnostic capabilities, and
develop targeted therapies specifically tailored for young
patients.
Advancing Psychosocial Support
Recognizing the emotional toll of blood disorders on young
patients, there is a growing emphasis on enhancing
psychosocial support services. Pediatric hematologists are
increasingly integrating mental health professionals into
their teams to provide counseling and support to both
children and their families. This holistic approach
acknowledges the importance of mental well-being
alongside medical treatment, fostering resilience and coping
mechanisms in young patients facing the challenges of
blood disorders.
Conclusion
Pediatric hematology stands at the intersection of medical
expertise, compassion, and innovation. Navigating the
unique challenges presented by blood disorders in children
requires a comprehensive understanding of both
hematology and pediatrics. As advancements continue to
shape the landscape of pediatric healthcare, the
collaborative efforts of healthcare professionals,
researchers, and advocates are essential for ensuring that
young patients receive the specialized care they need. By
addressing the complexities of pediatric hematology,
including psychosocial support, we can pave the way for
brighter and healthier futures for children facing blood-
related challenges.
Pearl Shaw
24 | Nov 2023 www.insightscare.com
Final file 5 Most Trusted Hematology Solution Providers to Watch in 2023.pdf
Final file 5 Most Trusted Hematology Solution Providers to Watch in 2023.pdf

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Final file 5 Most Trusted Hematology Solution Providers to Watch in 2023.pdf

  • 1. November Issue 04 2023 Maryland Oncology Hematology Providing Advanced Cancer Care Through Compassion and Care Dr. Mohit Narang US Oncology Research Maryland Oncology Hematology 5 5 to Watch in 2023 Hematology Most Trusted Solution Providers + A Critical Analysis The Role of Hematology in Modern Medicine Pediatric Hematology Addressing Unique Challenges in Young Patients
  • 2.
  • 3. Ensuring an invigorated and sustainable future for hematology and, in particular, non-malignant hematology, is key strategic priorityfor the society. Ensuring an invigorated and sustainable future for hematology and, in particular, non-malignant hematology, is key strategic priorityfor the society. Martin S. Tallman
  • 5. In the dynamic world of hematology, we’re diving into something big. Our latest edition of Insights Care is all about breaking new ground, and we’re focusing on what makes it happen in hematology – Precision, Progress, and Promise. Precision in hematology is like personalizing your playlist, but for healthcare. It’s about tailoring the approach to each patient, using advanced tools and treatments that fit like a glove. And who’s leading the charge? Meet the innovators – the companies and individuals making precision in hematology a reality. Now, let’s talk Progress. This isn’t just about moving forward; it’s about taking giant leaps. We’re exploring the cool stuff happening in labs and clinics – from understanding hematological disorders better to trying out new therapies. And who’s behind these strides? The companies and experts at the forefront of hematology, making waves in progress. And then there’s Promise. It’s not just a word; it’s a commitment to a brighter tomorrow. We’re showcasing the latest technologies and approaches that have the potential to change the game in hematology. Who’s turning this promise into reality? The companies and visionaries who are shaping the future of hematology care. As you flip through this edition, 5 Most Trusted Hematology Solution Providers to Watch in 2023, think about it like you’re on a journey – not a grand quest, but an honest exploration of what’s happening in hematology today. These stories aren’t just about cool science; they’re about real people, real progress, and a real promise for better health. Insights Care proudly presents this deep dive into Breaking New Ground, inviting you to join the ride, get to know the innovators, and discover the human side of hematology. Hope you have an interesting read! Pearl Shaw Managing Editor
  • 6. Maryland Oncology Hematology Providing Advanced Cancer Care Through Compassion and Care 08
  • 7. A Critical Analysis Pediatric Hematology Xcene Research Changing the Sub-Saharan Africa Landscape of Clinical Research The Role of Hematology in Modern Medicine Addressing Unique Challenges in Young Patients Articles Pro le 18 14 22
  • 8. Copyright © 2023 Insights Success Media and Technology Pvt. Ltd., All rights reserved. The content and images used in this magazine should not be reproduced or transmitted in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, without prior permission from Insights success. Reprint rights remain solely with Insights Success Media and Technology Pvt. Ltd. Insights Care is powered by Insights Success Media and Technology Pvt. Ltd. November, 2023 sales@insightscare.com Contact Us: Follow us on : www.facebook.com/InsightsCare/ https://twitter.com/Insightscare Insights Success Media Tech LLC 555 Metro Place North, Suite 100, Dublin, OH 43017, United States Phone - +1614-602-4132 Email: info@insightscare.com For Subscription: www.insightscare.com Insights Success Media and Technology Pvt. Ltd. Survey No.133/134, Brand Square, Office No. 512, Kunjir Chowk, Pimple Saudagar, Pune, Maharashtra 411027. Phone - India: 7410033802, 8956487823 Email: info@insightscare.com For Subscription: www.insightscare.com Editor-in-Chief Chidiebere Moses Ogbodo Managing Editor Pearl Shaw Executive Editor Natalie May Visualiser David King Art & Design Head Samuel Martinez Co-designer Paul Belin Art & Picture Editor Grace Brown Business Development Manager Emily Jones Marketing Manager Bill Thompson Business Development Executives Anna Smith, Jack Miller Sales Executives Mike, Carl, John Technical Head Jacob Smile Assistant Technical Head Joseph Taylor Technical Consultants David, Robert Digital Marketing Manager Alina Sege Assistant Digital Marketing Manager Daniel Jones SME-SMO Executives Gemson Research Analyst Eric Smith Circulation Manager James Carter We are also available on :
  • 9. Brief Featuring Person Company MediSix Therapeutics is developing game- changing T-cell therapies by leveraging an array of proprietary technologies that improve and expand T-cell function. SEHH is dedicated to advancing Hematology in Spain, fostering excellence, transparency, patient- centric care, and global leadership in healthcare. Maryland Oncology Hematology is dedicated to providing the most advanced cancer care available anywhere in an atmosphere of caring compassion. MediSix Therapeutics medisixtx.com Andrew Bruce CEO Dr. Mohit Narang MD Jorge Sanchez MD Maryland Oncology Hematology marylandoncology.com Sociedad Española de Hematología y Hemoterapia sehh.es Sysmex Corporation is a global leader in healthcare, specializing in innovative diagnostic solutions and cutting-edge medical technologies. Hisashi Ietsugu CEO Sysmex sysmex.co.jp Xcene Research pioneers clinical research, specializing in Sub-Saharan Africa, offering end-to- end services with trust, quality, and efficiency. Adebukunola Telufusi Executive Director Xcene Research xceneresearch.com 5 5 to Watch in 2023 Hematology Most Trusted Solution Providers +
  • 10. Maryland Oncology Hematology Providing Advanced Cancer Care Through Compassion and Care We’re a part of the US Oncology network, which gives us access to additional resources. We’re able to reach out to other physicians to get the best answers for our patients. Cover Story
  • 11. Dr. Mohit Narang US Oncology Research Maryland Oncology Hematology
  • 12. ancer is a devastating disease that affects millions Cof people worldwide. Cancer care from diagnosis to treatment and beyond requires a multidisciplinary team of healthcare professionals who work together to provide personalized care, support, and guidance throughout the cancer journey. Providing advanced cancer care with compassion is essential for not only treating the physical symptoms but also addressing the emotional and psychological aspects of cancer. Maryland Oncology Hematology is known for being present and willing to support each person who experiences a variety of emotions associated with cancer, or blood disorder/disease. Its dedicated physicians, nurses, and staff guide the diagnosed through several treatment options, tailoring services to unique, individual needs. As the treatment begins, factors like—relationships with others, management of side effects from treatment, nutrition, and diet become an important part of treatment. And the physicians and staff center are dedicated to helping with so that the patients can navigate through this challenging time with ease. Four major types of treatments for cancer could be expected at Maryland Oncology Hematology: Ÿ Biologic/targeted therapies: A newer type of cancer treatment that can more precisely attack cancer cells using a combination of drugs and other substances. These therapies work differently than traditional chemotherapy drugs. Ÿ Chemotherapy: This treatment uses anti-cancer drugs to treat cancer by stopping or slowing the growth of cancer cells. Ÿ Radiation Therapy: Advanced radiotherapy delivery methods are used to target and treat a wide range of malignancies. This treatment is designed to target and destroy cancerous cells by preventing them from growing or dividing while minimizing adverse effects on nearby healthy organs and tissues. Ÿ Surgery: For some cancers, surgery may be used to remove all or part of the cancer to prevent spread. The clinic today is the largest independent Medical Oncology and Hematology group in Maryland with 40 physicians practicing in fifteen locations across central Maryland. It is united in healing with the US Oncology Network, one of the nation’s largest community-based cancer treatment and research networks focused on advancing cancer care in America. This network has over 1000 physicians and 10,000 cancer professionals nationwide. When Dr. Mohit Narang, M.D, met other physicians there, he immediately knew that he has found his second family who were just as driven in providing excellent patient care, as he was. Let’s dive in to know about Maryland Oncology Hematology’s operations in providing the most advanced care available anywhere in an atmosphere of caring and compassion. Source of Inspiration Maryland Oncology Hematology was started in the late 90s by Jon Minford, MD. It is a community-based practice taking care of patients locally. The center had five full-time oncologists at the time. Maryland Oncology Hematology’s one of the goals is to provide cutting-edge treatment and research to patients in its community, both for benign hematology and oncology. Our guiding principle is the patient comes irst. Patient care should be held to the highest standard. If there’s the care we cannot provide, we try to ind that care for that patient in the best place possible. We consider ourselves the quarterback for the patient. 5 Most Trusted Hematology Solution Providers to Watch in 2023
  • 13. Thus, in the past decade, the center has grown from five physicians to 52 physicians, with 12 offices in Maryland. Journey So Far After finishing a fellowship at Michigan State University, Dr. Mohit Narang moved to Arkansas and opened the first cancer center in Batesville,before starting a group purchasing organization for more than 100 oncologists. From there, he moved to Maryland, where he’s been practicing medicine ever since. Before moving, Dr. Narang had a choice between coming to Maryland, and moving to Boston and joining a practice there. He and his family chose Maryland because they enjoyed the lifestyle here, and they were happy with the schools, but the practice was also a major factor. When he met the other physicians there, Dr. Narang knew they were driven by the patients. The goal of the practice was to provide excellent patient care first, and that was a priority to him “The practice does feel like a family to me. I like to say I have two marriages—my wife and this practice,” says Dr. Narang. Dr. Narang has been a top Baltimore physician in colon cancer, prostate cancer, and hematology for the past four years in a row. He has published more than a hundred articles and has more than 70 active studies going on his sites Dr. Narang is also a member of the American Society of Hematology, the American Society of Clinical Oncology, and the European Society of Medical Oncology, the International Extranodal study group, Advisor CONNECT Myeloma study group. Core Values Maryland Oncology Hematology’s guiding principle is the patient comes first. Patient care should be held to the highest standard. “If there’s the care we cannot provide, we try to find that care for that patient in the best place possible. We consider ourselves the quarterback for the patient,” adds Dr. Narang. Compassionate Care Services For Maryland Oncology Hematology, patient comfort comes first. “Our patients aren’t a number, they’re an individual. We provide care in a timely, punctual manner, for both cancer patients and our patients with benign hematological conditions,” says Dr. Narang. “We can open many research studies in less than two weeks. If a patient comes to us with a rare form of cancer or has a rare mutation, we can start the research treatments in no time. Elsewhere, they may have to travel across the country, or even internationally. We can provide studies in the office, close to home, which is a huge advantage for our patients.” He continues, “Although we are a cancer center, we also do infusions for benign conditions for gastroenterology, rheumatology, Neurology and Cardiology. So we’re a composite of both an infusion center and a cancer center.” Cutting-Edge Treatments It’s important for the physicians at Maryland Oncology Hematology, to stay up to date on cutting edge treatments. “We’re a part of the US Oncology network, which gives us access to additional resources,” said Dr. Narang “We’re able to reach out to other physicians to get the best answers for our patients.” As a community-based practice focused on providing top-level care to patients locally, it’s important Our patients aren’t a number, they’re an individual. We provide care in a timely, punctual manner, for both cancer patients and our patients with benign hematological conditions.
  • 14. for the clinic to stay updated and grow with the research and advancements, so that the patients are offered the best care that they need. Words of Wisdom For the budding enthusiasts who aim to venture into the healthcare sector, Dr. Narang suggests, “If you are planning to venture into healthcare, you need to love this field. Please do not join for commercial reasons. I think the key thing to remember is healthcare is more than a vocation. You’re with your patients through a crucial part of their life. You’re with their families. That’s what’s important, and that needs to be a driving factor.” Looking Ahead Looking ahead to 2023, Maryland Oncology Hematology’s goal is to grow, especially geographically. “We are also opening phase one study sites, which are not always available to patients who cannot travel to a university to receive those treatments. We are trying to open CAR-T sites. We want to make care more accessible and affordable where our patients already live.” We can open many research studies in less than two weeks. So if a patient with rare cancer or has a rare mutation, we can start the research treatments in no time. Elsewhere, they may have to travel across the country, or even internationally. We can provide studies in the of ice, close to home, which is a huge advantage for our patients.
  • 15.
  • 16. ematology, the branch of medicine that focuses Hon studying blood and blood-related disorders, plays a pivotal role in modern healthcare. As medical science advances, our understanding of hematology becomes increasingly critical in diagnosing, treating, and preventing various diseases. In this article let’s delve into the multifaceted aspects of hematology, examining its significance, recent advancements, and the evolving landscape of its applications in contemporary medicine. Understanding Hematology At its core, hematology encompasses the study of blood and its components, including red and white blood cells, platelets, and plasma. The discipline goes beyond identification and classification; it explores the intricate mechanisms governing blood function and its role in maintaining overall health. Hematologists, armed with advanced diagnostic tools, delve into the microscopic realm to unravel the complexities of blood-related disorders, ranging from anemia to leukemia. Hematology in Disease Detection One of the primary contributions of hematology to modern medicine lies in its diagnostic capabilities. Blood tests have become indispensable tools for identifying many conditions, from routine check-ups to critical illnesses. Hematological factors such as complete blood count (CBC) and blood smears provide valuable insights into an individual’s overall health. For instance, red blood cell count alterations, hemoglobin levels, or platelet counts can be early indicators of various diseases. A low red blood cell count may signal anemia, while abnormal white blood cells may suggest infections or autoimmune disorders. By scrutinizing these microscopic elements, hematologists can diagnose and initiate treatment promptly, often preventing the progression of diseases to advanced stages. The Role of Hematology Modern Medicine in 14 | Nov 2023 www.insightscare.com
  • 17. A Critical Analysis 15 | Nov 2023 www.insightscare.com
  • 18. Cancer Diagnosis and Monitoring Hematology emerges as a frontline player in the battle against cancer. Leukemia, a cancer affecting the blood and bone marrow, is a critical factor in oncology.Through sophisticated techniques such as flow cytometry and molecular testing, hematologists can identify specific markers associated with various types of leukemia, allowing for precise diagnosis and tailored treatment strategies. Moreover, hematology plays a crucial role in monitoring cancer patients undergoing treatment. Regular blood tests enable healthcare providers to assess the effectiveness of therapies, adjust treatment plans, and manage potential side effects. This dynamic monitoring is instrumental in improving patient outcomes and enhancing the overall quality of cancer care. Advancements in Molecular Hematology Advancements in molecular biology have significantly reshaped the landscape of hematology. The advent of genetic testing and molecular profiling has revolutionized our understanding of blood disorders at the molecular level. Inherited conditions such as hemophilia and thalassemia can now be diagnosed with greater precision, enabling healthcare professionals to offer targeted therapies and personalized treatment plans. Molecular hematology also extends its reach to the realm of hematologic malignancies. Identifying genetic mutations associated with conditions like myelodysplastic syndromes (MDS) and lymphomas has paved the way for novel therapeutic approaches, including targeted therapies and immunotherapies. This precision medicine approach positively impacts outcomes and reduces side effects compared to conventional treatments. Blood Transfusion Medicine Hematology’s influence extends to the critical domain of blood transfusion medicine, ensuring the safety and efficacy of blood transfusions. Blood transfusions are integral in various medical interventions, including surgeries, trauma care, and treatments for certain medical conditions. Working in tandem with blood banks, hematologists meticulously screen donated blood for infectious agents and compatibility, minimizing the risk of transfusion-related complications. In addition to traditional blood transfusions, advancements in hematology have led to the development of therapies such as stem cell transplantation. This innovative approach holds immense potential for treating various blood disorders, including leukemia and lymphoma. Hematopoietic stem cells, capable of differentiating into different blood cell types, offer a lifeline for patients facing otherwise limited treatment options. Challenges and Future Directions While hematology continues to make significant strides, challenges persist. Disorders such as sickle cell anemia and rare blood cancers present ongoing hurdles that demand focused research efforts and innovative therapeutic interventions. The field is also facing the task of adapting to the changing healthcare environment, including integrating artificial intelligence and machine learning in diagnostics and treatment decision-making. As we look to the future, collaborations between hematologists, geneticists, and other specialists become increasingly vital. The interdisciplinary approach will facilitate a more comprehensive understanding of blood disorders and foster the development of targeted therapies. Moreover, ongoing research in stem cell biology and regenerative medicine holds the promise of groundbreaking treatments that could revolutionize the management of various hematologic conditions. Conclusion In conclusion, hematology is a cornerstone in modern medicine, driving advancements in diagnostics, treatment strategies, and our overall understanding of blood-related disorders. From cancer diagnosis to blood transfusion safety, the contributions of hematologists are invaluable in enhancing patient outcomes and shaping the healthcare landscape. As technology progresses, hematology’s role will undoubtedly expand, reaffirming its status as a critical player in the ongoing pursuit of medical excellence. Pearl Shaw 16 | Nov 2023 www.insightscare.com
  • 19. Stay in touch. Subscribe to Insights Care and get the magazine in print, & digital on www.insightscare.com Never Miss An Issue Subscribe Today Corporate Office Insights Success Media Tech LLC 555 Metro Place North, Suite 100, Dublin,OH 43017, United States Phone - (614)-602 - 1754,(302)-319-9947 Email: info@insightscare.com For Subscription : www.insightscare.com Cheque should be drawn in favor of : INSIGHTS SUCCESS MEDIA TECH LLC www.insightscare.com
  • 20. Xcene Research Changing the Sub-Saharan Africa Landscape of Clinical Research The process of drug development is generally a complex and highly regulated area of the healthcare industry. Therefore, it is important to work with someone who has a thorough understanding of the process, combined with a depth of therapeutic expertise to get your new products and treatments out into the market. Xcene Research is one such contract research organization (CRO), with a focus on providing high-quality services, with a special focus on emerging markets across Sub- Saharan Africa. The company offers comprehensive support to pharmaceutical, biotechnology, and medical device companies, as well as academic research institutions, across the region. Xcene Research understands the unique challenges associated with clinical research in Africa, and thus, it is dedicated to overcoming them. By leveraging its deep knowledge of the local regulatory landscape and cultural sensitivities, the company helps its clients navigate the clinical development process smoothly and efficiently. The company aligns its operations with the core value of trust. This is reflected through its standards of on-time performance, delivery of uncompromising quality, complete visibility into project status and optimal communication to manage client goals. As a result, it has become a trusted partner for clinical research in Africa and is making a significant impact in the industry. In an interview with Insights Care, Adebukunola Telufusi, the Executive Director explains how through its work, the company is helping to advance medical knowledge, improve access to high-quality medical care, and enhance the healthcare landscape in Sub-Saharan Africa and beyond. Following are the excerpts from the interview: Please brief our audience about the company. What led to its inception? Xcene Research is an indigenous African Contract Research Organization (CRO) bringing clinical trials to a more diverse population in Sub-Saharan Africa. As a leading CRO, we provide full-service support to pharmaceutical, biotechnology, and medical device companies, as well as academic research institutions across Sub- Saharan Africa. With a diverse population and bearing the greatest disease burden in the world, the African continent can provide many of the conditions optimal for carrying out clinical trials. Xcene Research sees the opportunity to breach the gap in healthcare and is bringing more clinical trials to an expansive genetically diverse population and in turn, improving interventions for Africans. Can you elaborate upon the core values on which the company is built and what is its mission? Xcene's core values revolve around five distinct principles guiding all our processes, systems, and culture. These are Ethics, Innovation, Quality, Progress, and Partnership. We Xcene Research is an indigenous African Contract Research Organiza on (CRO) bringing clinical trials to a more diverse popula on in Sub-Saharan Africa. As a leading CRO, we provide full-service support to pharmaceu cal, biotechnology, and medical device companies, as well as academic research ins tu ons across Sub- Saharan Africa. 5 Most Trusted Hematology Solu on Providers to Watch in 2023 18 | Nov 2023 www.insightscare.com
  • 21. Adebukunola Telufusi started as the Founder of Xcene Research and has 15 years of experience in enabling community development and social development goals in Africa. Her career spans working with top-ten global pharmaceu cal companies and CROs as a consultant and project manager with experience in regulatory requirements regarding the conduct of clinical trials in Sub-Sahara Africa and the US. Her therapeu c experience spans from Phase I through Phase IV trials in Hematology, pediatrics, cardiovascular disease, CNS, diabetes, oncology, neurology, medical devices, vaccines, and women's health. Adebukunola put together a team that is the core founda on of Xcene th Research. Currently, in its 8 year, the company has grown exponen ally, and studies have been brought to Africa with a diversity-first mindset. "Xcene focuses on the following 21 therapeu c areas including – Hematology, Cardiovascular, Nephrology, Pediatrics, Oncology, Infec ous disease and Sickle cell disease which is our biggest por olio. Our Sub-Sahara footprints across 6 ac ve sites including Nigeria, Ghana, Kenya, Uganda, Tanzania, and Kenya," says Adebukunola. Buki as she is fondly called and Xcene are intertwined, and both have had a fulfilling journey to bring in medica ons and grant pa ents access to healthcare. Innova on and collabora on are the company's watchwords with the aim of becoming an impac ul healthcare solu on provider to Africa. Adebukunola Telufusi in Brief Adebukunola Telufusi Execu ve Director Xcene Research 19 | Nov 2023 www.insightscare.com
  • 22. are dedicated to building strategic partnerships across the globe as we look to improve the health system across sub- Saharan Africa and when it comes to global health, we believe that innovation and collaboration are the keys to progress. Our mission is to be a catalyst for accelerated access to life- saving treatments which speaks to our dedication to building strategic partnerships across the globe with the highest standards of delivery as we look to improve global health issues across Sub-Sahara Africa. Tell us more about the services that make your company stand out from the competition. Xcene Research has extensive relationships with leading pharmaceutical and biotechnological companies, regulators, and medical centers as well as experienced investigators across Sub-Sahara Africa, Europe and the USA. This gives us unparalleled access to patients, patient data, and the expertise and perspective of physicians who are leaders in their field. Our clinical research professionals identify, translate, and answer complex questions while working with sponsors to advance the practice and the future of medicine. All studies conducted by Xcene Research are in- line with global regulations and ICH-GCP standards. Key areas of our services cut across: Site Startup, Clinical Trial Monitoring, Site Intelligence & Activation, Site Training, Data Management, Project Management, IRB Submission, Patient Recruitment, Regulatory Development, Central Laboratory, Clinical Supplies, Quality & Compliance, Medical & Safety Management. What is your opinion on healthcare providers' aligning their offerings with newer technological developments, especially when it comes to catering to the dynamic needs of the healthcare space? We consider technological developments and capabilities a path to fundamentally transform healthcare systems and these priorities will continue to evolve. It is pertinent to align with new developments because the impact of technological transformation will be felt across all aspects of health care, enabling easier access to care, improving quality, and decreasing the cost of care. Consumers can connect quickly and conveniently with their preferred provider. In addition to stronger patient relationships, such innovations can also help improve operational and financial efficiencies and bring health systems' long-term strategies into reality. What advice would you like to give to budding entrepreneurs and enthusiasts aspiring to venture into the healthcare niche? Zeal, focus, be informed and be impact driven. It is essential that aspiring budding entrepreneurs gain a good understanding of what medical entrepreneurship implies and equip themselves with the know-how and skills they need to thrive in this environment. Networking and meeting the right people can help expand their network while reconciling social purpose and profit should be considered in their business operations. There is always room for improvement, so staying in the know and bringing innovation to the table will propel them on the path to success. How do you envision scaling the company's services and operations in 2023 and beyond? We do foresee Xcene being the number one healthcare provider in Africa. In the pipeline of services to extend our offerings, is the Xcene Laboratory Diagnostics (XLD) which would be launched in Q4 of 2023. It is one of its kind to complement clinical trials sample analysis conducted by Xcene research across sub-Sahara Africa and will serve as a central Laboratory for clinical trials for other CROs and healthcare institutions across Africa for analysis. The Xcene Research Academy (XRA) to be launched in Q3 of 2023 will further add capacity to bridge the gap in clinical research and provide technical and industry knowledge to Africa's next generation of researchers. The Impact Africa Summit (IAS), which is a brainchild of Xcene Research, was inaugurated in 2020 to build sustainable capacity for clinical research through partnerships in Africa. The summit has brought together 1500+ attendees, 7 Sub-Saharan Regulators, 50+ speakers and 14 workshops, forums, and scientific symposiums. We aim to continue to work on our processes and finetune them to stand as the go-to CRO across Africa. 20 | Nov 2023 www.insightscare.com
  • 23.
  • 24. Pediatric Hematology Addressing Unique Challenges Young Patients in 22 | Nov 2023 www.insightscare.com
  • 25. ediatric hematology, the specialized branch of Pmedicine focused on blood disorders in children, presents a distinct set of challenges and considerations. Understanding and managing blood-related conditions in young patients require a nuanced approach that factors in the unique aspects of pediatric physiology, development, and emotional well-being. In this article, we delve into the intricacies of pediatric hematology, exploring the challenges healthcare professionals face and the strides made in ensuring optimal care for young patients. Pediatric Blood Disorders Blood disorders in children encompass a broad spectrum of conditions, ranging from common ones like anemia to rare genetic disorders such as hemophilia and thalassemia. Diagnosing and treating these disorders in pediatric patients require a specialized skill set, considering the physiological differences between children and adults. Pediatric hematologists, equipped with expertise in both hematology and pediatrics, play a pivotal role in addressing these unique challenges. Diagnostic Dilemmas Diagnosing blood disorders in children poses distinctive challenges due to the variability in normal blood values at different stages of development. For instance, a lower red blood cell count in a child may not necessarily indicate 23 | Nov 2023 www.insightscare.com
  • 26. anemia but could be within the normal range for their age. Pediatric hematologists employ age-specific reference ranges and carefully consider developmental factors to accurately diagnose and differentiate between benign variations and potential disorders. Communication and Emotional Considerations Caring for pediatric patients involves not only addressing the physical aspects of their conditions but also navigating the emotional and psychological impact on the child and their family. Effective communication is paramount in pediatric hematology, requiring healthcare professionals to convey complex information in a manner that is age- appropriate and sensitive to the child’s developmental stage. Pediatric hematologists often collaborate with child life specialists and psychologists to create a supportive environment, easing the anxieties associated with medical procedures and chronic illnesses. Building trust with young patients and their families is essential for successful management and adherence to treatment plans. Unique Treatment Approaches Treatment modalities in pediatric hematology must be tailored to the specific needs of children, considering factors such as growth, development, and potential long- term effects. Medication dosages, for instance, need to be carefully calculated based on a child’s weight and age. Furthermore, the choice of treatment may be influenced by the potential impact on the child’s quality of life, growth, and development. In the case of hematologic malignancies, pediatric oncology and hematology collaborate closely to provide comprehensive care. The treatment of childhood cancers often involves multi-disciplinary teams, including surgeons, radiation oncologists, and nurses, working together to ensure the best possible outcomes for young patients. Innovations in Pediatric Hematology Advancements in pediatric hematology have significantly improved the outlook for young patients facing blood disorders. Precision medicine, with its focus on tailored therapies based on genetic and molecular profiles, holds promise for more effective and less invasive treatments. Research in gene therapy and targeted therapies specifically designed for pediatric blood disorders is underway, offering hope for improved outcomes and reduced side effects. Education and Advocacy Addressing the unique challenges in pediatric hematology extends beyond the clinic and hospital walls. Educational initiatives aimed at parents, caregivers, and schools contribute to early detection and effective management of blood disorders in children. Increased awareness fosters a supportive community that understands the specific needs of pediatric patients and promotes a holistic approach to their care. Additionally, advocacy for pediatric hematology research and funding is crucial for driving innovation and improving the standard of care. By raising awareness at the policy level, stakeholders can ensure that resources are allocated to advance research, enhance diagnostic capabilities, and develop targeted therapies specifically tailored for young patients. Advancing Psychosocial Support Recognizing the emotional toll of blood disorders on young patients, there is a growing emphasis on enhancing psychosocial support services. Pediatric hematologists are increasingly integrating mental health professionals into their teams to provide counseling and support to both children and their families. This holistic approach acknowledges the importance of mental well-being alongside medical treatment, fostering resilience and coping mechanisms in young patients facing the challenges of blood disorders. Conclusion Pediatric hematology stands at the intersection of medical expertise, compassion, and innovation. Navigating the unique challenges presented by blood disorders in children requires a comprehensive understanding of both hematology and pediatrics. As advancements continue to shape the landscape of pediatric healthcare, the collaborative efforts of healthcare professionals, researchers, and advocates are essential for ensuring that young patients receive the specialized care they need. By addressing the complexities of pediatric hematology, including psychosocial support, we can pave the way for brighter and healthier futures for children facing blood- related challenges. Pearl Shaw 24 | Nov 2023 www.insightscare.com