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Stenting: tips and tricks
Colin Berry
University of Glasgow
Scotland, UK
i2 Fellows Bootcamp  Tuesday, March 27, 2007
Dr Colin Berry
Disclosure
The presenter has received SIGNIFICANT
research funding from Medtronic Inc.
(Europe)
Learning objectives
• Primary / direct stenting
• Stenting in acute myocardial infarction
• Stenting tips and tricks in complex
cases
Primary objective :
avoid adverse outcomes
Baseline angiogram Post mid - LAD stent
Tips and tricks for stenting:
Guide catheter size
5 Fr simple procedures
‘+’ ve - direct stenting / reduced bleeding
‘-’ ve -  risk air embolus / IVUS won’t go
6 Fr simple or complex procedures
may accommodate 2 balloons
(selected manufacturers)
7 Fr complex procedures
bifurcations, rotational atherectomy
blood loss - consider hemostasis valve
Stenting tips and tricks :
Guide catheter choice
LCA
• specialized guide catheters appropriate for
artery : XB LAD vs. EBU or AL for Cx
• left main length (short = less aggressive guide)
RCA
• take-off superior vs horizontal vs inferior
• avoid side-hole catheters as pressure may
falsely disguise wedging and vessel injury
PTCA vs. primary stent ?
PTCA Primary Stent
Anatomy Distal location + / -
Tortuous
vessels
+ / -
Lesion Non-calcified + / -
RD < 2.0 mm RD  2mm
Distribution
Patient
Small jeopardy
score
Low risk
> Small
In general, stents are superior
 Acute complications;  restenosis
PTCA technique
Long balloon, low inflation pressure, long inflation time
Standard balloon
2.5 x 20 mm
Dilated @ 6 atmos
Distal
lesion
Stenting strategy
Direct
stenting
Predilation +
stenting
Lesion
characteristics
Non-ostial Ostial
Uniform Non-uniform
Non-calcified Calcified
Acute lesion
(thrombectomy)
Occluded
Simple Complex (long,
bifurcations)
Stenting in acute MI
• Ensure wire is endoluminal
• If thrombus present – aspirate; medicate
• Occluded artery - establish antegrade
flow by predilation
• Direct stent only if lesion adequately
visualized
• Post-dilate, only if necessary
Direct stenting in acute MI
Not appropriateAppropriate
Tips and tricks :
lesion preparation
PREDILATION
• Final balloon : lesion diameter 0.8 – 1.0 : 1
• Consider incrementally larger balloons,
1.5 – 2 mm followed by 2.5 – 3 mm
Adjunctive devices - rotational atherectomy for
calcified lesions, including bifurcations
OBJECTIVE
• Achieve optimal lesion modification prior to
stenting
Which stent to use ?
BMS DES
Patient
characteristics
No diabetes
Low-risk
Diabetes
Major co-morbidity
(surgery intended,
terminal cancer,
‘palliative’ PCI – CABG
intended)
Low bleeding risk
Lesion
characteristics
RD  3.5 mm *RD 2.75 – 3.5 mm
Ca2+ - achieve
optimal stent
deployment
*SIRIUS : small < 2.75 & long > 18 mm vessels
SCAI – ACC guidelines 2005; 2007
Risk of stent thrombosis
• SCAI
CCI 2007
Stent dimensions
• Stent diameter
artery : stent ratio = 1 : 1.1
do not oversize – acute complications
plan possibility of post - dilation
• Stent length
Lesion coverage
DES – 1 - 2 mm proximal & distal to stent to ensure
complete plaque coverage: normal to normal
IVUS to asses result
Tips and tricks :
stent deployment
Stent procedure
• Slow inflation to nominal pressure
(avoid balloon dumb-bell effect )
• Short inflation (15 - 20 sec)
• Optimal inflation pressure > 14 A
• Analyze angiographic result in orthogonal
views
Tips and tricks:
stent deployment
Post-dilatation
• Select semi-compliant or non-compliant
balloon
• Routine high-pressure (> 18 A) to ensure
adequate stent expansion
• Stent under-expansion (focal or generalized) ?
IVUS for stent assessment, especially if DES
Tips and tricks
Prevent stent malpositioning
• Stent motion prior to deployment can cause
geographic miss (particularly in RCA)
• Partial inflation 1 – 3 A will lead to inflation of
balloon at stent extremities prior to stent
expansion.
• Therefore, small adjustments to the stent
position can be made
Ormiston CCI 2000
Tips and tricks
Bifurcations
Provisional Stenting
1 stent is usually better than 2
Indications for 2 Stents
• SB is an important artery (large distribution, RD > 2
mm, dominant vessel) + SB disease
CRUSH – wire position in MB secure; quick, procedure,
limiting ischemic time
CULOTTE – angle < 70°
T – angle > 70
Can’t access side-branch
access?
Tips and tricks :
can’t access side-branch ?
1. Guide cath: coaxial; correct configuration
2. Guide-wire: recross stent
Wire access to side-branch (SB) stent : floppy,
hydrophilic Whisper; steerable-catheter
3. Balloon access to SB – conventional balloon; if it
doesn’t pass then use a low profile & short balloon ie
1.5 x 8 mm; or 1.25 mm
4. Main branch post-dilation at bifurcation
5. Anchor technique – advance MB balloon beyond
bifurcation, inflate, then advance SB balloon
6. Fixed wire system – balloon on a wire
Anchor technique : successful
side-branch access?
Side-branch access achieved
Kissing balloons optimizes final result
Stenting tips and tricks:
achieve what you set out to do
Stenting: tips and tricks
Take Home Points: KEEP IT SIMPLE !
1. Lesion preparation
for optimal stent deployment
2. Stent strategy
think through the possible eventualities
3. What is best for the patient
Restenosis : thrombosis ratio DES vs. BMS
Risk of stent thrombosis? Duration of clopidogrel?
Thankyou for your attention
Primary objective :
procedural success
Acute stent thrombosis
Stenting: tips and tricks
Importance of final kissing balloon dilation
Ormiston CCI 2004; 63: 332-336
Stenting: tips and tricks
Approach to Kissing Balloon inflations
• Individual balloon sizes should equal 2/3rds of
proximal reference vessel diameter
• Final inflation should be an appropriately sized
balloon in MB (especially for “Crush”
• SB balloons should be deflated before or
simultaneous with MB balloon
Stenting: tips and tricks
Bifurcation lesions
• T stents: angle < 90º, incomplete SB cover
• Crush technique: SB inflation then final kissing
balloon inflation are essential
•  70° - kissing balloon’s are ideal
• > 70 ° - “ “ are inadequate stent
expansion, therefore sequential post-dilatations
followed by Kissing balloons
Stenting: tips and tricks
Kissing Balloons ?
• Correct stent deformations, even when not-
angiographically apparent
• Increase SB ostium minimum lumen area (> 5 mm2)
• .. Leading to reduced SAT and reduced TLR
• May facilitate reintervention
Stenting: tips and tricks
Long lesions
• Stent length – independent predictor of intra-
procedural stent thrombosis; sub-acute thrombosis,
restenosis
• IVUS
• Anti-thrombotic treatments : IIbIIIa inhibitor, aspirin,
clopidogrel
Reference vessel diameter
• Stent size: 1.1 : 1
- undersizing acute long term complications
- oversizing IPST, dissections
- Smaller arteries – less likely to achieve 100% stent
expansion or > 5 mm2 stent area
• IVUS – to assess final minimum lumen area
Stenting: tips and tricks

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Fb stenting tips_and_tricks

  • 1. Stenting: tips and tricks Colin Berry University of Glasgow Scotland, UK i2 Fellows Bootcamp  Tuesday, March 27, 2007
  • 2. Dr Colin Berry Disclosure The presenter has received SIGNIFICANT research funding from Medtronic Inc. (Europe)
  • 3. Learning objectives • Primary / direct stenting • Stenting in acute myocardial infarction • Stenting tips and tricks in complex cases
  • 4. Primary objective : avoid adverse outcomes Baseline angiogram Post mid - LAD stent
  • 5. Tips and tricks for stenting: Guide catheter size 5 Fr simple procedures ‘+’ ve - direct stenting / reduced bleeding ‘-’ ve -  risk air embolus / IVUS won’t go 6 Fr simple or complex procedures may accommodate 2 balloons (selected manufacturers) 7 Fr complex procedures bifurcations, rotational atherectomy blood loss - consider hemostasis valve
  • 6. Stenting tips and tricks : Guide catheter choice LCA • specialized guide catheters appropriate for artery : XB LAD vs. EBU or AL for Cx • left main length (short = less aggressive guide) RCA • take-off superior vs horizontal vs inferior • avoid side-hole catheters as pressure may falsely disguise wedging and vessel injury
  • 7. PTCA vs. primary stent ? PTCA Primary Stent Anatomy Distal location + / - Tortuous vessels + / - Lesion Non-calcified + / - RD < 2.0 mm RD  2mm Distribution Patient Small jeopardy score Low risk > Small In general, stents are superior  Acute complications;  restenosis
  • 8. PTCA technique Long balloon, low inflation pressure, long inflation time Standard balloon 2.5 x 20 mm Dilated @ 6 atmos Distal lesion
  • 9. Stenting strategy Direct stenting Predilation + stenting Lesion characteristics Non-ostial Ostial Uniform Non-uniform Non-calcified Calcified Acute lesion (thrombectomy) Occluded Simple Complex (long, bifurcations)
  • 10. Stenting in acute MI • Ensure wire is endoluminal • If thrombus present – aspirate; medicate • Occluded artery - establish antegrade flow by predilation • Direct stent only if lesion adequately visualized • Post-dilate, only if necessary
  • 11. Direct stenting in acute MI Not appropriateAppropriate
  • 12. Tips and tricks : lesion preparation PREDILATION • Final balloon : lesion diameter 0.8 – 1.0 : 1 • Consider incrementally larger balloons, 1.5 – 2 mm followed by 2.5 – 3 mm Adjunctive devices - rotational atherectomy for calcified lesions, including bifurcations OBJECTIVE • Achieve optimal lesion modification prior to stenting
  • 13. Which stent to use ? BMS DES Patient characteristics No diabetes Low-risk Diabetes Major co-morbidity (surgery intended, terminal cancer, ‘palliative’ PCI – CABG intended) Low bleeding risk Lesion characteristics RD  3.5 mm *RD 2.75 – 3.5 mm Ca2+ - achieve optimal stent deployment *SIRIUS : small < 2.75 & long > 18 mm vessels SCAI – ACC guidelines 2005; 2007
  • 14. Risk of stent thrombosis • SCAI CCI 2007
  • 15. Stent dimensions • Stent diameter artery : stent ratio = 1 : 1.1 do not oversize – acute complications plan possibility of post - dilation • Stent length Lesion coverage DES – 1 - 2 mm proximal & distal to stent to ensure complete plaque coverage: normal to normal IVUS to asses result
  • 16. Tips and tricks : stent deployment Stent procedure • Slow inflation to nominal pressure (avoid balloon dumb-bell effect ) • Short inflation (15 - 20 sec) • Optimal inflation pressure > 14 A • Analyze angiographic result in orthogonal views
  • 17. Tips and tricks: stent deployment Post-dilatation • Select semi-compliant or non-compliant balloon • Routine high-pressure (> 18 A) to ensure adequate stent expansion • Stent under-expansion (focal or generalized) ? IVUS for stent assessment, especially if DES
  • 18. Tips and tricks Prevent stent malpositioning • Stent motion prior to deployment can cause geographic miss (particularly in RCA) • Partial inflation 1 – 3 A will lead to inflation of balloon at stent extremities prior to stent expansion. • Therefore, small adjustments to the stent position can be made Ormiston CCI 2000
  • 19. Tips and tricks Bifurcations Provisional Stenting 1 stent is usually better than 2 Indications for 2 Stents • SB is an important artery (large distribution, RD > 2 mm, dominant vessel) + SB disease CRUSH – wire position in MB secure; quick, procedure, limiting ischemic time CULOTTE – angle < 70° T – angle > 70
  • 21. Tips and tricks : can’t access side-branch ? 1. Guide cath: coaxial; correct configuration 2. Guide-wire: recross stent Wire access to side-branch (SB) stent : floppy, hydrophilic Whisper; steerable-catheter 3. Balloon access to SB – conventional balloon; if it doesn’t pass then use a low profile & short balloon ie 1.5 x 8 mm; or 1.25 mm 4. Main branch post-dilation at bifurcation 5. Anchor technique – advance MB balloon beyond bifurcation, inflate, then advance SB balloon 6. Fixed wire system – balloon on a wire
  • 22. Anchor technique : successful side-branch access?
  • 23. Side-branch access achieved Kissing balloons optimizes final result
  • 24. Stenting tips and tricks: achieve what you set out to do
  • 25. Stenting: tips and tricks Take Home Points: KEEP IT SIMPLE ! 1. Lesion preparation for optimal stent deployment 2. Stent strategy think through the possible eventualities 3. What is best for the patient Restenosis : thrombosis ratio DES vs. BMS Risk of stent thrombosis? Duration of clopidogrel?
  • 26. Thankyou for your attention
  • 27. Primary objective : procedural success Acute stent thrombosis
  • 28. Stenting: tips and tricks Importance of final kissing balloon dilation Ormiston CCI 2004; 63: 332-336
  • 29. Stenting: tips and tricks Approach to Kissing Balloon inflations • Individual balloon sizes should equal 2/3rds of proximal reference vessel diameter • Final inflation should be an appropriately sized balloon in MB (especially for “Crush” • SB balloons should be deflated before or simultaneous with MB balloon
  • 30. Stenting: tips and tricks Bifurcation lesions • T stents: angle < 90º, incomplete SB cover • Crush technique: SB inflation then final kissing balloon inflation are essential •  70° - kissing balloon’s are ideal • > 70 ° - “ “ are inadequate stent expansion, therefore sequential post-dilatations followed by Kissing balloons
  • 31. Stenting: tips and tricks Kissing Balloons ? • Correct stent deformations, even when not- angiographically apparent • Increase SB ostium minimum lumen area (> 5 mm2) • .. Leading to reduced SAT and reduced TLR • May facilitate reintervention
  • 32. Stenting: tips and tricks Long lesions • Stent length – independent predictor of intra- procedural stent thrombosis; sub-acute thrombosis, restenosis • IVUS • Anti-thrombotic treatments : IIbIIIa inhibitor, aspirin, clopidogrel
  • 33. Reference vessel diameter • Stent size: 1.1 : 1 - undersizing acute long term complications - oversizing IPST, dissections - Smaller arteries – less likely to achieve 100% stent expansion or > 5 mm2 stent area • IVUS – to assess final minimum lumen area Stenting: tips and tricks