Kim Solez Seizing the opportunity of technology and the future of medicine c...Kim Solez ,
Kim Solez Ishita Moghe Seizing the opportunity of technology and the future of medicine creating the possibility of a positive medical future for everyone1 Medical Grand Rounds Presentation Feb. 1, 2019.
Kim Solez Seizing the opportunity of technology and the future of medicine c...Kim Solez ,
Kim Solez Ishita Moghe Seizing the opportunity of technology and the future of medicine creating the possibility of a positive medical future for everyone1 Medical Grand Rounds Presentation Feb. 1, 2019.
Texas Medical Association History of Medicine Gallery's first online presentation: "Courage and Determination," the popular history of African-American physicians in Texas.
this is a copy of my CV/resume. I'd be interested in working with some other doctors who'd be interested in doing the best of alternative, scientific integrative medicine as found in the scientific literature such as Pubmed of the National Library of Medicine, Journal of Orthomolecular Medicine, and Life Extension Foundation. We could also do conventional "allopathic" medicine, if the patients specifically wanted this, but I would not like to work with anyone, or any place, not open to this possibility. Patients should be entitled to the best, and also have the choice.
Tuskegee Tests
Provides information as to the REASONS why the FEDERAL BUREAU OF INVESTIGATION, JUDICIAL COMPLAINTS and CONGRESSIONAL COMPLAINTS Filed by Vogel Denise Newsome are being OBSTRUCTED from being PROSECUTED!
Garretson Resolution Group appears to be FRONTING Firm for United States President Barack Obama and Legal Counsel/Advisor (Baker Donelson Bearman Caldwell & Berkowitz) which has submitted a SLAPP Complaint to OneWebHosting.com in efforts of PREVENTING the PUBLIC/WORLD from knowing of its and President Barack Obama's ROLE in CONSPIRACIES leveled against Vogel Denise Newsome in EXPOSING the TRUTH behind the 911 DOMESTIC TERRORIST ATTACKS, COLLAPSE OF THE WORLD ECONOMY, EMPLOYMENT violations and other crimes of United States Government Officials. Information that United States President Barack Obama, The Garretson Resolution Group, Baker Donelson Bearman Caldwell & Berkowitz, and United States Congress, etc. do NOT want the PUBLIC/WORLD to see. Information of PUBLIC Interest!
The Doctor and the Good Life - Introduction to Bioethics and Natural LawAmiel Villanueva
Second version of my lecture on medical ethics / bioethics to the Learning Unit II class of the UP College of Medicine as part of IDC 201: History of Medicine. This was presented last May 9, 2018.
Slide design by SlidesCarnival (slidescarnival.com)
Texas Medical Association History of Medicine Gallery's first online presentation: "Courage and Determination," the popular history of African-American physicians in Texas.
this is a copy of my CV/resume. I'd be interested in working with some other doctors who'd be interested in doing the best of alternative, scientific integrative medicine as found in the scientific literature such as Pubmed of the National Library of Medicine, Journal of Orthomolecular Medicine, and Life Extension Foundation. We could also do conventional "allopathic" medicine, if the patients specifically wanted this, but I would not like to work with anyone, or any place, not open to this possibility. Patients should be entitled to the best, and also have the choice.
Tuskegee Tests
Provides information as to the REASONS why the FEDERAL BUREAU OF INVESTIGATION, JUDICIAL COMPLAINTS and CONGRESSIONAL COMPLAINTS Filed by Vogel Denise Newsome are being OBSTRUCTED from being PROSECUTED!
Garretson Resolution Group appears to be FRONTING Firm for United States President Barack Obama and Legal Counsel/Advisor (Baker Donelson Bearman Caldwell & Berkowitz) which has submitted a SLAPP Complaint to OneWebHosting.com in efforts of PREVENTING the PUBLIC/WORLD from knowing of its and President Barack Obama's ROLE in CONSPIRACIES leveled against Vogel Denise Newsome in EXPOSING the TRUTH behind the 911 DOMESTIC TERRORIST ATTACKS, COLLAPSE OF THE WORLD ECONOMY, EMPLOYMENT violations and other crimes of United States Government Officials. Information that United States President Barack Obama, The Garretson Resolution Group, Baker Donelson Bearman Caldwell & Berkowitz, and United States Congress, etc. do NOT want the PUBLIC/WORLD to see. Information of PUBLIC Interest!
The Doctor and the Good Life - Introduction to Bioethics and Natural LawAmiel Villanueva
Second version of my lecture on medical ethics / bioethics to the Learning Unit II class of the UP College of Medicine as part of IDC 201: History of Medicine. This was presented last May 9, 2018.
Slide design by SlidesCarnival (slidescarnival.com)
20 significantly Brave Leaders who contributed to Medicine | CIO Women MagazineCIOWomenMagazine
Many human pursuits depend on leadership to succeed. Sports, education, the arts, journalism, law, the military, and medicine may all attribute their success to the kind of leadership supplied.
Cleveland State University[email protected]Journal of Law WilheminaRossi174
Cleveland State University
[email protected]
Journal of Law and Health Law Journals
2001
Lessons Taught by Miss Evers' Boys: The
Inadequacy of Benevolence and the Need for Legal
Protection of Human Subjects in Medical Research
Donald H.J. Hermann
DePaul University
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Human Subjects in Medical Research, 15 J.L. & Health 147 (2000-2001)
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147
LESSONS TAUGHT BY MISS EVERS’ BOYS: THE
INADEQUACY OF BENEVOLENCE AND THE NEED FOR
LEGAL PROTECTION OF HUMAN SUBJECTS IN MEDICAL
RESEARCH
DONALD H.J. HERMANN1
Legal regulation and ethical constraints on medical research are again at the
forefront of public policy concerns. The reported deaths of a volunteer in a gene
therapy research program at the University of Pennsylvania and of a participant in an
asthma experiment at the Johns Hopkins Medical Center have raised issues of the
adequacy of government surveillance of medical research and the adequacy of
current practices eliciting voluntary informed consent from research participants.2
The recognition of the need for legal constraints on medical research and for
protection of human subjects was greatly influenced by the reports of the research
conducted by Nazi doctors and scientists.3 While no one denies the atrocities
committed under the guise of medical research in the Third Reich, there has also
been recognition of the significant abuse of research subjects in the United States,
most recently in the reports of the Federal Advisory Committee on Human Radiation
experiments.4 Perhaps the most publicized research involving failure to pr ...
Kim Solez Seizing the opportunity of technology and the future of medicine c...Kim Solez ,
Kim Solez Ishita Moghe Seizing the opportunity of technology and the future of medicine creating the possibility of a positive medical future for everyone Medical Grand Rounds Presentation Feb. 1, 2019.
Kiosk-Style Slide Presentation with some interactivity presented at Purdue University Teaching, Learning, and Technology Conference 2003. Must download to fully experience.
Julio Licinio is initially from Brazil but he lived for more than 2 decades in US, where he got his clinical and research training and education in psychiatry and endocrinology at University of Chicago, Cornell and Albert Einstein College of Medicine.
Presentation on knowledge synthesis methodologies with a focus on engineering, for University of Michigan, October 25, 2023. Overview of the broader context, then focuses in on systematic reviews and tech mining.
PF Anderson presents for OLLI-UM on February 25, 2021. Graphic Medicine describes the genre of comics and graphic novels around healthcare, as told from personal and professional perspectives. Many think of comics as for children, but that could be risky with some of these! The personal experiences described can be tender or gritty, and touch on topics such as specific conditions, social justice, dying, lived experiences, resilience. Visual aspects of storytelling take advantage of new literacies, offering insights not possible through other mediums.
Brief lightning talk for UofM THL, repeated for MLA Research Caucus on January 27, 2021. On the subject of using systematic review search skills in combination with non-systematic review research methodologies.
As part of the #GraphicMedLibs panel for the August 5, 2020 NNLM NER webinar on Graphic Medicine, PF Anderson discussed awareness of #OwnVoices issues in both comics creation and collections, along with strategies and tools to utilize the #OwnVoices movement in the creation of community and awareness of social justice themes in #GraphicMedicine. This presentation represents the work of PF Anderson (UM-THL) with collaborators Claire Myers (UMSI), Gina Genova (UMSI), Susan Brown (Ypsilanti District Library), and David Carter (UM-AAEL).
"Research core facilities are centralized shared research resources that provide access to instruments, technologies, services, as well as expert consultation..." That sounds a lot like a library to me. What would look different about libraries if we thought of them as a research core facility?
This was a presentation for a research lab at the University of Michigan, May 28, 2019.
A storytelling workshop collaboration with Melissa Cunningham (Office of Patient Experience), Alex Fox (School of Public Health), and Patricia F. Anderson (Taubman Health Sciences Library). The focus of the workshop was on tools and strategies for telling patient and healthcare stories.
Slide deck for the Dent 610 graduate level course on research methods, 2018 version; collaboratively developed by Mark MacEachern, Patricia F. Anderson, and Tyler Nix.
Presented at Meaningful Play 2018, East Lansing, Michigan. Please note, the website for the game (http://aberrantry.com/) is in development at this time. The game code is in GitHub, & a download link is available at the website.
A design thinking approach to rapidly developing comics concepts. Workshop presentation by PF Anderson, University of Michigan. Developed for the Office of Health Equity and Inclusion.
Using design thinking strategies to help bootstrap developing a comic concept. A workshop presentation by PF Anderson for Enriching Scholarship, 2018, at the University of Michigan.
Tips and tricks for writing abstracts for science research articles to maximise citations and impact. Presented at the University of Michigan in May 2018.
A basic introduction to rapid reviews, created for a graduate student workshop, March 2018, presented by PF Anderson from the University of Michigan. Includes links to more resources, standards and guidelines, tools, software, and more.
A strategic approach to crafting abstracts for life sciences research publications to maximize their discovery in search engines as well as utility and citability for audiences beyond other researchers. This workshop was designed for the University of Michigan North Campus Research Center community.
A session for the Dent 610 course at the University of Michigan, on research methods and processes. Specific focus of this session on systematic review methods and processes, especially through database searching.
A presentation by Dr. David Cheney for the Investing in Abilities 2017 lecture series, on emerging technologies and tech strategies for empowerment, especially focused on using education to crowdsource solutions to interesting problems and develop compassion and a sense of humanity.
A presentation by Dr. Michelle A. Meade for the Investing in Abilities 2017 lecture series, on emerging technologies and tech strategies for empowerment.
Slides for a lightning round talk presented at Comics and Medicine, Seattle, also known as Graphic Medicine Conference, 2017. The project presented was by PF Anderson, Elise Wescom, Kai Donovan, and Ruth Carlos, and originally published in the December 2016 issue of the Journal of the American College of Radiology (JACR).
A poster by Kai Donovan, Elise Wescom, Mark Chaffee, Jean Song, Breanna Hamm, and Chase Masters for the 2017 Annual Meeting of the Medical Library Association.
More from University of Michigan Taubman Health Sciences Library (20)
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Famous and Lesser Known Members of the University of Michigan Medical School Who Have Made a Difference: A Historical View
1. Famous and Lesser Known Members of the University of Michigan Medical School Who Have Made a Difference: A Historical View Anna Schnitzer, AMLS, Merle Rosenzweig, AMLS, Stephanie Swanberg, MSI, and Katy Mahraj, MSI Candidate University of Michigan Taubman Health Sciences Library Keith L. Black, M.D. (1957-) Dr. Keith Black is an American neurosurgeon born in Auburn, Alabama who published his first scientific paper at age 17, earning the Westinghouse Science Award. At the University of Michigan, Black earned both his undergraduate and medical degrees in six years as well as completed an internship in general surgery and residency in neurological surgery. Black is a pioneer researcher in the blood brain barrier and brain tumors. His research interests include gene arrays to develop molecular profiles of tumors, use of optical technology to map the brain, and the use of microwave energy to non-invasively destroy brain tumors. Currently, Black is Chairman and Professor, Department of Neurosurgery and Director of the Maxine Dunitz Neurosurgical Institute at the Cedars-Sinai Medical Center.1 Milestones 1981 Graduates from University of Michigan Medical School 1987 Completes residency and fellowship at University of Michigan Medical School & becomes Head of the Comprehensive Brain Tumor Program at the UCLA Medical Center 1997 Director of the Division of Neurosurgery at Cedars-Sinai Medical Center 1997 Founds the Maxine Dunitz Neurosurgical Institute at Cedars-Sinai 2007 Opens the Cochran Brain Tumor Center at Cedars Sinai Benjamin S. Carson, Sr., M.D. (1951-) Born in Detroit and emerging from an impoverished childhood, Dr. Benjamin Carson is now one of the most renowned neurosurgeons of our time. He attended Yale University with a degree in Psychology and continued his education at the University of Michigan Medical School. One of his most recognized triumphs is the first successful separation of Siamese twins joined at the back of the head in addition to further advancements in pediatric neurosurgery, oncology, and plastic surgery. Carson has received over 50 honorary degrees and awards, including the Presidential Medal of Freedom in 2008. Currently, he is the Director, Division of Pediatric Neurosurgery at the Johns Hopkins Medical Institutions and president and co-founder of the Carson Scholars Fund for young people.3 Milestones 1977 Graduates from University of Michigan Medical School 1987First separation of craniopagus (Siamese) twins joined at the back of the head 1997 First successful placement of an intrauterine shunt for a hydrocephalic twin in South Africa 2008 Receives the Presidential Medal of Freedom from President George W. Bush Antonia C. Novello, M.D., M.P.H. (1944-) Dr. Antonia Novello is recognized as the first woman and first Hispanic to be appointed the Surgeon General of the United States. Born in Puerto Rico, she earned her undergraduate and medical degrees at the University of Puerto Rico. Traveling to the United States, she completed her pediatric internship and residency at the University of Michigan In addition to subspecialty training in pediatric nephrology at UM and Georgetown University. Novello entered the Public Health Service in 1978 and served as the 14th Surgeon General of the United States from 1990-1993. In 2009, after serving seven years as the 13th New York State Health Commissioner and managing the September 11th disaster, the New York Inspector General brought up charges against Novello with one count of defrauding the government, three counts of filing a false instrument and sixteen counts of theft of government services.Novellopleaded guilty to one felony charge with all other charges being dropped.2 Milestones 1970 Begins her studies at the University of Michigan as a pediatric intern and resident 1990 Becomes first woman and first Hispanic Surgeon General of the United States 1999 Appointed the 13th New York State Health Commissioner, a position she held until 2006 2009 Pleads guilty to one felony count of filing a false instrument in a case by the New York Inspector General Victor C. Vaughan, M.D. (1851-1929) Dr. Victor Vaughan worked in many capacities during his medical career. He contributed to biochemistry, hygiene, public health, and medical education reform, including through his best known role as Dean of the University of Michigan Medical School from 1891 to 1920. However, Vaughan’s story is not all glory. He was a strong supporter of eugenics and as a member of the Michigan State Board of Health, was influential in the passage of legislation approving compulsory sterilizations. Vaughan felt that sterilization would benefit its victims and create a more humane society. The law applied to “mentally defective or insane” people under the care of public institutions. Only one sterilization occurred before the law was found unconstitutional by the Michigan State Supreme Court.5 Milestones 1889 Develops one of the first systematic courses on bacteriology and term theory for medical students 1891 BecomesDean of the University of Michigan's Medical School, where he is Dean until 1920 1913 Instrumental in working to have the state legislators pass a compulsory sterilization law in 1913 1914 Begins a term as president of the American Medical Association 1915 Helps to found the National Board of Medical Examiners James V. Neel, M.D. , Ph.D. (1915-2000) Dr . James Neel is lauded as the father of modern human genetics and one of the first people to articulate the importance of human genetics in diagnosis and treatment of disease. Neel completed his M.D. and Ph.D. at the University of Rochester, New York. He accepted a position at the University of Michigan Medical School in 1946, where he worked for 39 years. Neel became a professor in the Department of Internal Medicine and the Department of Human Genetics and served as Chairman of the Department of Human Genetics from 1956 to 1981. Neel served on numerous committees from a local to global level and received many accolades for his work. His research covered numerous topics, including sickle cell anemia, affects of atomic radiation, consanguineous marriage, and the “thrifty gene” hypothesis.4 Milestones 1946 Begins studies of the effects of radiation exposure in survivors of the atomic bomb in Japan 1946 Joins the University of Michigan as assistant geneticist in the Laboratory of Vertebrate Biology 1948 Helps establish the American Society of Human Genetics and writes the first paper for the American Journal of Human Genetics 1952 Establishes the University of Michigan Heredity Clinic, the groundwork for the Department of Human Genetics, founded in 1956 and the first such department in the nation 2010 1890 2000 1995 1980 1970 1960 1950 1910 1900 1985 1990 2005 Francis S. Collins, M.D., Ph.D. (1950-) Dr. Francis Collins is a leading physician-geneticist renowned for his discoveries of various disease genes. After a three-year fellowship at Yale University in Human Genetics, Collins joined the University of Michigan departments of Internal Medicine and Human Genetics in 1984. In his research, Collins developed a new method for identifying genes, coined ‘positional cloning,’ in which scientists can identify disease genes without knowing in advance what the functional abnormality underlying the disease might be. He is most famous for identifying the gene responsible for cystic fibrosis, but has also discovered genes linked to Huntington's disease, neurofibromatosis, and the M4 type of adult acute leukemia. In his career, Collins has served as the Director of the National Center for Human Genome Research, received the 2007 Presidential Medal of Freedom and the 2009 National Medal of Science and is now the Director of the National Institutes of Health.7 Milestones 1989 Identifies gene for cystic fibrosis 1993 Becomes Director of the National Center for Genome Research 1994 Founds the National Human Genome Research Institute Division of Intramural Research 2000 Announcement of the Human Genome Project’s a working draft of the human genome sequence 2009 Becomes Director of the National Institutes of Health Alexa Canady-Davis, M.D. (1950-) Dr. Alexa Canady-Davis, born in Lansing, is the first African American woman to become a neurosurgeon in the United States. Training as a resident in neurosurgery at the University of Minnesota and completing a fellowship in pediatric surgery at Children’s Hospital of Philadelphia, Canady-Davis became an expert in cranio-facial abnormalities, hydrocephalus, tumors of the brain, and congenital spine abnormalities. She has served as Chief of Neurosurgery at Children’s Hospital of Michigan and Professor of Neurosurgery at Wayne State University and received numerous awards including Woman of the Year by the American Women's Medical Association in 1993, as well as being inducted into the Michigan Women's Hall of Fame.8 Milestones 1975 Graduates cum laude from the University of Michigan Medical School 1976 Becomes the first African American woman neurosurgeon in the United States 1987 Chief of Neurosurgery at Children’s Hospital of Michigan 1997 Professor of Neurosurgery at Wayne State University School of Medicine Herman W. Mudgett (1861?-1896) Herman Mudgett, also known as Dr. Henry Howard Holmes, is considered to be America’s first known serial killer. Mudgettwas expelled from the University of Michigan Medical School in 1884 for stealing corpses. Many details of Mudgett’s life are uncertain, including the exact number of his victims, as Mudgett frequently modified his story. In 1893, he built and opened a hotel in Chicago for the World’s Fair. This hotel was the site of many of his murders and housed soundproof rooms, a stretching rack, and doors that opened only from the outside. He sold several of his victims’ skeletons and organs to medical schools. He was arrested in 1894, found guilty of murder, and executed by hanging in 1896.10 Milestones 1884 Expelled from the University of Michigan Medical School 1893 Builds and opens a hotel in Chicago for the 1893 World’s Fair. This hotel was the location of many of his murders. 2003 Erik Larson publishes Devil in the White City: Murder, Magic and Madness at the Fair that Changed America, a novel exploring Mudgett’s murders and the planning of the 1893 World’s Fair. Jonas E. Salk, M.D. (1914-1995) Dr. Jonas Salk, the son of Russian-Jewish immigrants, was the first in his family to attend college. At the City College of New York, he developed an interest in medicine. His first work with viruses began with research into the influenza virus. In 1947, Salk began his work at the University of Pittsburgh Medical School in collaboration with the National Foundation for Infantile Paralysis to find a vaccine for polio. He worked for eight years on the project and in 1955, he announced his success; an announcement that was made here at the University of Michigan. Salk chose not to patent his vaccine so that it could be distributed as widely as possible. After this work, Salk went on to found the Jonas Salk Institute for Biological Studies in 1963. He continued to research viruses, working on a vaccine against AIDS until his death at age 80 in 1995.9 Milestones 1942 Research Fellowship at the University of Michigan 1947 Works with the National Foundation for Infantile Paralysis (Polio) to develop a vaccine 1953 Thomas Francis, Jr. begins field trials of his former protégé Jonas Salk’s polio vaccine. 1955 On April 12, Thomas Francis, Jr. and Jonas Salk at the University of Michigan’s Rackham Auditorium announced that the Salk Vaccine was “safe, effective, and potent” against polio. Jacob ‘Jack’ Kevorkian, M.D. (1928-2011) Jack Kevorkian aka ‘Dr. Death’ is infamously known as a fervent advocate of doctor-assisted suicide for terminally ill patients. Born in Pontiac, Kevorkian attended the University of Michigan Medical School, studying to be a pathologist, and served as an Army medical officer during the Korean War. In his early career at UM hospital and later Pontiac General Hospital, Kevorkian displayed an obsession with death and dying, studying patient’s eyes to determine the exact moment of death, and publishing radical ideas on the testing & use of euthanasia for inmates and terminally-ill patients.1990 marked his first public assisted suicide of Janet Adkins, an elderly woman with Alzheimer’s and awakened the local community, state authorities, and the nation. In 1998, CBS’s 60 Minutes broadcast the lethal injection of Thomas Youk, a sufferer of Lou Gehrig's disease. Immediately following, Kevorkian was arrested, charged with second-degree murder, tried, and sentenced to 10–25 years in prison. He was released in 2007 after only serving eight years of his sentence for good behavior.6 Milestones 1952 Graduates from University of Michigan Medical School 1990 First public assisted suicide of Janet Adkins, an elderly woman diagnosed with Alzheimer’s 1998 CBS’s 60 Minutes broadcasts the lethal injection of Thomas Youk 2007 Released from prison for good behavior after only eight years of his sentence for second-degree murder 1 KEVIN L. BLACK: Cedars-Sinai Medical Center. “Keith L. Black.” http://www.cedars-sinai.edu/Patients/Programs-and-Services/Cancer-Center/Expert-Team/Neuro-Oncology/Keith-L-Black.aspx; The Black Scholars Index. “Keith L. Black” http://www.blackscholarsindex.com/2010/02/keith-l-black-md-chairman-and-professor-department-of-neurosurgery-director-maxine-dunitz-neurosurgical-institute/. 2 ANTONIA C. NOVELLO: The Chinese American Scholars and Professionals Association. "Antonia Novello, MD: Keynote Speaker." http://www.caspaf.org/conference2010/BIOS/AntoniaNovello-p1.pdf; New York Daily News. "Former state Health Commissioner Antonia Novello pleads guilty to felony" http://articles.nydailynews.com/2009-06-26/news/17924862_1_plea-deal-governor-pataki-shopping-trip 3 BENJAMIN S. CARSON: Carson Scholars Fund. “General Information” http://carsonscholars.org/content/dr-ben-carson/general-information; Benjamin S. Carson, Sr., M.D. “Curriculum Vitae,” http://www.hopkinsmedicine.org/bin/s/i/benjamin_carson.pdf; Ben Carson, M.D. “St. Louis Speaker’s Series” Maryville University, St. Louis, http://www.maryville.edu/event8600.htm 4 JAMES V. NEEL: John P. McGovern Historical Collections and Research Center. “The Papers of James. V. Neel.” http://mcgovern.library.tmc.edu/collect/manuscript/Neel/Neel_intro.htm; University of Michigan Medical School. “James V. Neel, U-M Professor and Father of Modern Human Genetics, Died Feb. 1 At Age 84.” http://www.ibis-birthdefects.org/start/neel3.htm; University of Michigan Department of Human Genetics. “About Us: Timeline.” http://sandbox.hg.med.umich.edu/about.php#timeline . 5 VICTOR C. VAUGHAN: Markel, Howard. “The Cover.” http://jama.ama-assn.org/content/283/7/848.full.pdf ; Kaelber, Lutz. “Michigan.” http://www.uvm.edu/~lkaelber /eugenics/MI/MI.html. 6 JACK KEVORKIAN: Biography. “Jack Kevorkian.” http://www.biography.com/articles/Jack-Kevorkian-9364141; Criminal Brief Blog. “Jack Kevorkian” http://criminalbrief.com/?p=7887. 7 FRANCIS S. COLLINS: National Center of Human Genome Research Institute. “Francis S. Collins.” http://www.genome.gov/10001018; Northwestern University, Feinberg School of Medicine. “Francis Collins Lecture.” http://www.feinberg.northwestern.edu/news/past-years/2010/2010I-April/nih-video/NIH_Director_at_Northwestern_video.html. 8 ALEXA CANADY-DAVIS: The Historymakers.“Dr. Alexa Canady-Davis Biography.” http://www.thehistorymakers.com/biography/biography.asp?bioindex=1619&category=MedicalMakers; Delta Sigma Theta. “Famous Delta Sigma Theta.” http://nurize.com/greeks/Images/Sorority/African%20American/Delta%20Sigma%20Theta/Nurize%20Delta%20Sigma%20Theta.html 9 JONAS E. SALK: Academy of Achievement. “Jonas Salk, M.D.” http://www.achievement.org/autodoc/page/sal0bio-1. 10 HERMAN W. MUDGETT: “H. H. Holmes.” http://en.wikipedia.org/wiki/H._H._Holmes; Spinder, Cara. “Mr. Herman Mudgett, aka H. H. Holmes.” http://michigantoday.umich.edu/99/Sum99/mt15j99.html.