1
A	Unit	of	the	Med	School	Office	of	Research
Investing	in	Abilities
Panel Discussion
Connie	Chang,	MBA
Managing	Director,	FFMI
Oct	5,	2017
1
2
3 3
4
Crossing	the	Chasm
Research Faculty
and Students
LEVEL OF TECHNOLOGY
DEVELOPMENT
Entrepreneurs and
Business Community
Research
Resources
Commercialization
Resources
“Valley of Death”
IDEAS
(Universities, Research
Institutes, Health Systems)
IMPACT
NEW PRODUCTS
for PATIENTS
(Private Sector)
10/5/17 4
5 5
IDEA
• Basic	
research
• Team	
science
Translation
• Model	
systems
• Technical	
proof	of	
concept
Clinic	/	
Community
• Human	trials
• Implement
• Integrate
IMPACT
• Patients
• Products
• Scale-up
A
B
C
The	right	team,	
The	right	problems
De-risking	ideas,
Know	your	customer,
Workflow	impact
Funding,
Business	model,
Finding	partners
6 6
7
Helping	biomedical	researchers	accelerate	
innovations	from	idea	to	impact,	
by	making	innovation	
a	natural	and	expected	academic	behavior
8
Innovations Across Verticals –
Guided by Faculty Champions and Innovation Council
Mike Holinstat, PhD
Pharmacology,
Cardiovascular Medicine
Dan Orringer, MD
Neurosurgery
Tim Cornell, MD
Pediatric Critical Care
Joyce Lee, MD, MPH
Pediatrics
10/5/17 8
9
Business	
Development
Build industry collaborations
Scale	as	an	
Innovation	Hub
Statewide and nationwide reach
and impact
Education
Tailored learning
for busy faculty and students,
clinicians and researchers
Funding+Mentors
Resources advancing biomedical
research to commercial paths
9
10
Education
FFMI	Commercialization	Education
• Programs	Accelerating	
Commercialization	
Education	(PACE)
– Focus	on	life	science	and	
biomed	commercialization
• For	faculty,	post	docs,	
trainees	and	students
• Partner where	possible	
with	ecosystem	partners
11
Education
10/5/17 11
• Needs	assessment
• Design	thinking
• Customer	discovery
• Value	proposition
• FDA	/	regulatory
• IP
• Business	case
12
N i k k i S y l i a n t e n g
@ t o p a r k o r n o t t o p a r kFrom	Joyce	Lee’s	“HUMAN-CENTERED	
DESIGN	FOR	HEALTH	CARE”
13 13
From	Joyce	Lee’s	“HUMAN-CENTERED	
DESIGN	FOR	HEALTH	CARE”
14 14
15
Funding	and	Mentorship
• Resources	advancing	
biomedical	research	
onto	viable	commercial	
paths
• Not	just	funding;	
coaching	and	
mentorship	are	key	
10/5/17 15
Follow-on	Funds
16
Commercialization	Funds
• Enhance	commercial	potential
• $25K-$50K	for	single	milestone		
• Review	panel	with	market	
expertise	
• Quarterly	reviews	and	awards
• FFMI	and	U-M	Tech	Transfer	
parntership
• Projects	with	high	potential	for	
commercial	success
• $100K-$250K	awards
– 1-year	of	funds,	late-stage	
translational	studies
16
Funding	&	
Mentorship
17
Industry Other	ExpertsInvestors
External	Advisors:	Project	
Selections	and	Mentorship
10/5/17 17
Funding	&	
Mentorship
18
Finding	Industry	Partners
• Build collaborations
• Creative new ways to
partner (contracts)
• Relationship
management
• Partner with other units
such as Business
Engagement Center
10/5/17 18
Business	
Development
19
Breadth	of	Industry	Partners
19
Business	
Development
10/5/17
20 20
21
Leading	Indicators	of	Results:	
(Med	School	only)
• Inventions,	Agreements • Industry	awards	($,	%total)
0
25
50
75
100
0
20
40
60
80
100
120
140
160
180
200
2012 2013 2014 2015 2016
NumberofAgreements
NumberofInventions
Fiscal Year
Inventions Agreements
Med	Startups FY12	 FY13 FY14 FY15 FY16
3 2 1 10 5
22
Broadening	FFMI	Impact
• Taking	most	FFMI	
programs	to	a		
statewide	model
• Education,	Business	
Development	and	
Funding/Mentorship
• Train-the-Trainer	for	
education	
dissemination	
10/5/17 22
Innovation	Hub
23
Thank	you!
• Questions?
• Please	contact	us!
Connie	Chang	(changco@umich.edu)
or
ffmioffice@umich.edu
innovation.medicine.umich.edu
10/5/17 23

Reinventing Normal 3: Connie Chang, Fast Forward Medical Innovation