The document discusses how open data and knowledge sharing can facilitate regional growth, using the agricultural sector as a case study. It describes Agro-Know, a company that captures, organizes, and adds value to agricultural information to make it universally accessible. It notes that open data is not always ready to be used directly and may require processing to improve quality. Opportunities exist for data-oriented small-to-medium enterprises to help organizations open their data and develop meaningful services using open data. The document provides examples of how open data could be used to build food safety infrastructure, support regional growth decision making, and localize open educational resources. It asks how knowledge could be better shared between EU/national and regional communities.