Europeans began exploring the Atlantic in the early 1500s, seeking to expand trade networks and spread Christianity. This led to encounters between European powers and indigenous societies in the Americas, Africa, and Asia. The Portuguese established coastal trading posts in Africa and fought Arabs for control of the spice trade. Spain formed the largest American empire through conquests led by Columbus, Cortes, and Pizarro. France founded Quebec in 1608 and grew the fur trade. England established 13 colonies along the eastern coast of North America in the 1600-1700s, with different economic focuses between the northern and southern regions.