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Chapter 2
Exercise Physiology
Fitness
• A. Being active improves health: 30 minutes of
     accumulated physical activity on most days
     of the week
• B. Being “fit” goes beyond health and requires a
     comprehensive exercise program that
  includes the following components
•   1)   Cardiorespiratory endurance
•   2)   Muscular strength and endurance
•   3)   Flexibility
•   4)   Body composition
•   5)   Balance
Components of Fitness
• 1) Cardiorespiratory endurance
  – The ability to perform large muscle movements over a
    sustained period
• 2a) Muscular strength
  – The max force that a muscle can produce against a
    resistance in a single maximal effort.
• 2b) Endurance
  – The capacity of a muscle to exert force repeatedly
    against a resistance
Components of Fitness
• 3) Flexibility
   – The range of motion around a joint
• 4) Body composition
   – The make-up of the body in terms of the relative
     percentage of fat free mass and body fat
• 5) Balance
   – The ability to maintain the body’s position over it’s
     base of support.
The 5 Fitness Components


                      Supply the body With O2    Involves the heart. Lungs, &
                      and remove wastes           blood vessels




                                                                   Ability of a muscle or group
                                                                   of muscles to exert maximal
 Ratio of lean body mass (muscles,                                force against a resistance
 tendons, organs, bone, etc.) to                                   1 rep max (how much weight
 fat mass                                                          you can lift on one repetition)
 What is your % body fat




                                                  Ability of a muscle, or group of
          Ability of a joint and surrounding
          muscles to move freely through          muscles to exert force over a period
                                                  of time against a resistance that is less
          its Range of Motion (ROM)
          How far can your muscle move           than max
                                                  How many times can you lift 80% of your max
          during stretches
Physiology of the Cardiorespiratory System
• For muscles to contract, they need energy in the form of
  ATP. The cardiorespiratory system is responsible for the
  three basic processes to produce this energy:
   – Get oxygen into the blood (oxygen-carrying capacity)
   – Deliver oxygen to the muscles (oxygen delivery)
   – Extract the oxygen from the blood to form ATP
     (oxygen extraction)
• Oxygen-carrying capacity is affected by two primary
  functions: (1) the ability to adequately ventilate the
  alveoli in the lungs and (2) hemoglobin concentration in
  the blood.
Basic Processes Blood Delivery
    and Nutrient Exchange
• 1) Pulmonary Ventilation
  – The total volume of gas inspired and expired
    per minute
• 2) Cardiac Output
  – The amount of blood pumped by the heart per
    minute
  – HR x SV
• 3) Oxygen Extraction
  – The amount of O2 taken from the HB Molecule
    and used in the exercising muscle.
Oxygen Delivery
• Oxygen delivery is a function of cardiac output (the
  quantity of blood pumped per minute).
   – Cardiac output (Q) = Stroke volume (SV) x Heart rate
     (HR) (in beats per min)
      • Stroke volume is the amount of blood pumped
        during each heartbeat.
   – Cardiac output increases due to increases in both SV
     and HR.
      • HR typically increases in a linear fashion up to
        maximal levels.
      • SV increases to about 40–50% of maximal
        capacity, and then plateaus.
Oxygen Extraction
• Oxygen extraction from the blood at the cellular level
  depends on muscle fiber type and the availability of
  specialized oxidative enzymes.
   – Slow-twitch muscle fibers are specifically adapted for
     oxygen extraction and utilization.
   – Aerobic production of ATP occurs in the mitochondria
     of the cells.
   – The circulatory system increases blood flow to the
     active muscles and decreases blood flow to non-
     active areas such as the viscera, allowing a higher
     concentration of O2 to be extracted.
Oxygen Consumption
• The more oxygen a person can take in, deliver, and
  utilize, the more work he or she can perform.
• VO2max refers to one’s maximal oxygen consumption.
   – It is expressed in either “relative” terms (mL/kg/min)
     or “absolute” terms (L/min).
   – Relative VO2max allows comparisons between
     individuals. Absolute VO2max is used to determine
     caloric expenditure during specific activities.
       • Approximately 5 kcal of energy are burned for
          every liter of oxygen consumed.
Energy production
• 1) Adenosine triphosphate (ATP)
•    a.Manufactured by the mitochondria in the muscle
            cell
•    b. ATP is the energy source used to drive muscle
            contraction
•    c. Fatty acids and glucose are used to produce ATP
•    d. Amino acids are not a preferred energy source,
     but are used in an undernourished individual
Energy production
Energy System   Substrate        Limitation to Produce          Primary Use
                                 ATP
ANAEROBIC
Phosphogen      Creatine         Muscle stores very little CP   High-intensity, short-
                phosphate (CP)   and ATP                        duration activities;
                Stored ATP                                      less than 10
                                                                seconds to fatigue
Anaerobic       Glucose and      Lactic acid build-up causes    High-intensity, short-
glycolysis      glycogen         rapid fatigue                  duration activities;
                                                                from 1–3 minutes
                                                                to fatigue

AEROBIC
                Fatty acids,     Depletion of muscle            Long-duration, sub-
                glucose, and     glycogen; insufficient O2      anaerobic threshold
                glycogen         delivery                       activities; longer
                                                                than 3 minutes to
                                                                fatigue
Anaerobic Threshold
• The anaerobic threshold (AT) is reached when exercise
  intensity increases above steady-state aerobic
  metabolism and anaerobic production of ATP occurs.
• When the AT is crossed, exercise can only be sustained
  for a few minutes before hyperventilation begins to
  occur.
   – Lactate accumulates progressively in the blood and
      the oxygen deficit and corresponding EPOC are
      extremely high.
   – At this point, the body attempts to rid excess CO 2 (a
      by-product of acid metabolites). The increase in
      respiration is called the second ventilatory threshold
      (VT2).
   – VT2 is an indirect indicator of AT.
Ventilatory Threshold
•   There are two distinct changes in breathing patterns during incremental exercise: the
    first ventilatory threshold (VT1) and the second ventilatory threshold (VT2).
•   VT1 occurs as soon as blood lactate begins to accumulate and the body needs to rid
    itself of excess CO2 through increased respiration.
     –   Can be identified using the “talk test.” It is the first point at which it becomes noticeably more
         difficult to speak.
•   VT2 occurs as blood lactate rapidly
    increases with intensity, and represents
    increased hyperventilation past the need
    to rid the body of excess CO2.
     –   Also known as lactate threshold (LT) and
         respiratory compensation threshold (RCT)
     –   Speaking is definitely not comfortable
         at this intensity.
Fuel Use During Exercise: Carbohydrates
•   Carbohydrates are the major food macronutrient for the metabolic
    production of adenosine triphosphate (ATP) and the only one whose stored
    energy can produce ATP anaerobically.
     – Stored as glycogen in the muscle and liver
         • Glycogenolysis (breakdown of liver glycogen to glucose) is the primary regulator of
           blood glucose.
     – Carbohydrates used during
       exercise come from both
       glycogen stores in muscle
       tissue and blood glucose.
         • The relative contribution
           of muscle glycogen and
           blood glucose used during
           exercise is determined by
           intensity and duration.
         • After the first hour of
           submaximal exercise,
           carbohydrate metabolism
           shifts from muscle
           glycogen to glycogenolysis
           in the liver.
Fuel Use During Exercise: Fats

• Fats are mainly stored as triglycerides in
  adipocytes, which must be broken down
  into FFAs and glycerol.
  – During low-intensity exercise, circulating FFAs
    from adipocytes are the primary energy
    source from fat, but during higher intensities,
    muscle triglyceride metabolism increases.
  – As duration increases, the role of plasma
    FFAs as a fuel source increases.
Fuel Use During Exercise: Protein
•   Protein plays a small role in the fueling of exercise. It must be
    broken down into amino acids, which can be supplied to the muscle
    tissue from the blood and from the muscle fiber itself.
    – Skeletal muscle can directly metabolize certain amino acids to produce
      ATP.
    – During exercise, glucose stored
      in a non-exercising muscle
      can be delivered indirectly
      to the exercising muscle
      via the glucose-alanine pathway.
Cardiorespiratory adaptations to
        acute aerobic exercise
• 1) Increased heart rate (HR)
• 2) Increased stroke volume (SV)
•    a.The amount of blood pumped from each ventricle
           each time the heart beats
•     b.Measured in mL per beat

• Cardiac output = HR x SV
Cardiorespiratory adaptations to
        acute aerobic exercise
• 3) Increased cardiac output
•    a.    Cardiac output = HR x SV
•      b.   A typical cardiac output at rest:
•           60 bpm x 70 mL/beat = 4200 mL/min
•           (approximately 1 gallon of blood per min)
• 4)        Increased breathing rate
Cardiorespiratory adaptations to
        acute aerobic exercise
• 5) Increased systolic blood pressure
•    a. Due to the cardiovascular system attempting to
            increase O2 delivery to the muscles
•     b.    However, blood pressure greater than
            250/115 mmHg is an indication to terminate
            exercise (hypertensive response)
Cardiorespiratory adaptations to
        acute aerobic exercise
• 6) No change (or a slight decrease) in diastolic
     blood pressure
•    a. Due to the dilation of vessels in the muscles and
            the skin
•     b. This decreases peripheral resistance (which is an
            important benefit for individuals suffering from
            heart disease, hypertension, diabetes, and
                   peripheral vascular disease)
Blood Pressure During Exercise
•   Systolic blood pressure has a much higher increase during exercise than diastolic
    blood pressure due to:
     –   Increased contractility of the heart
     –   Increased stroke volume
     –   The muscular need for greater force
         and pressure to deliver blood to
         the exercising muscles
     –   Vasodilation within the exercising
         muscle, which results in more blood
         draining from the arteries, through
         the arterioles, and into muscle
         capillaries, minimizing the change
         in diastolic pressure
Cardiorespiratory adaptations to
        acute aerobic exercise
• 7) Blood is shunted from the viscera to the
  working muscles
•    a.    Dilation of vessels that supply blood to the
                   exercising muscles
•     b.     Constriction of vessels that supply blood to
             the abdominal area
Cardiorespiratory adaptations to
      acute aerobic exercise
• 8) Increased extraction of oxygen from the
  blood into the working tissues
• a.   A normal, healthy person is able to load the blood
       with more O2 in the lungs than he or she is able to
       use at the cellular level
• b.   Therefore, the more efficiently an individual can
       extract O2 from the hemoglobin in the capillaries,
              the more fit he or she becomes
Chronic Training Adaptations to
           Exercise
 SAID principle (specific adaptation to imposed demands)
 Examples include:
– Improved cardiac output efficiency (increased SV and lower HR)
  (aerobic training)
– Increase in respiratory capacity (aerobic training)
– Increase in maximal oxygen consumption (aerobic training)
– Increase in bone density (weightbearing exercise)
– Improved control of blood glucose and lipids (physical activity)
– Maintained or improved lean body mass (weightbearing activity)
– Decreased depression and anxiety (physical activity)
– Higher quality of life (physical activity)
Cardiorespiratory adaptations due
       to regular aerobic exercise
• 1) Decreased RHR
•    a. With consistent exercise (as few as three months
       of regular aerobic training), the interior
       dimensions of the ventricles increase, allowing
       them to hold more blood
•      b. The same cardiac output can be maintained at a
       lower HR due to the greater SV
Cardiorespiratory adaptations due
       to regular aerobic exercise
• 2) Decreased relative working heart rate
•    a. Since a given intensity requires a given amount of
       O2, HR at any given intensity will be lower due to
             increased SV
•      b.    A trained individual will have to work at higher
             intensities to achieve the same HR he or she
                    achieved prior to being fit
Cardiorespiratory adaptations due
       to regular aerobic exercise
• 3) Increased VO2max as SV
  increases
• a. VO2max is the total capacity to consume
                oxygen at the cellular level
• b. VO2max depends on two factors
•      1.   The delivery of O2 to the working muscle by
            the blood (cardiac output)
•      2.   The ability to extract the O2 at the capillaries
            and use it in the mitochondria
Cardiorespiratory adaptations due
       to regular aerobic exercise
• 4) Increased O2 extraction
•          a.   Improved ability to remain “aerobic” at
                   higher intensities
•           b.     Increased capillary density
•           c.     Increased mitochondrial density
•           d.     Increased ability to create ATP
Cardiorespiratory adaptations due
    to regular aerobic exercise
• 5) Increased fatty acid oxidation at any
  submaximal intensity
• 6) More glycogen is stored in trained muscles
     and less lactic acid is produced
• 7) Increased tolerance to lactic acid produced
     during exercise
Exercising in the Heat
•   In addition to exercising in a hot, humid environment, other factors
    can cause heat overload.
     – Poor hydration prior to exercise
     – Overdressing
     – Overweight and obesity
•   During exercise, the internal heat load is brought to the skin’s
    surface to be cooled via the secretion of water by the sweat glands
    (evaporation).
     – The goal (given favorable environmental conditions) is to prevent body
       temperature from rising more than 2 to 3°F.
     – When the ability to dissipate heat is compromised, injuries occur.
Physiological Responses to Exercising in the Heat
•   Dissipating internal body heat is more difficult in the heat, resulting in a
    higher heart rate than normal at any level of exercise to maintain cardiac
    output.
•   A hot humid environment is the most stressful environment for exercising
    and poses the risk of heat exhaustion and heat stroke.
Safety in the Heat
•   The heat index, as presented on the next slide, provides guidelines
    on when exercise is safe and when it should be avoided.
•   Tips to consider before exercising in the heat:
     –   Begin gradually
     –   Always wear lightweight, well-ventilated clothing
     –   Avoid impermeable or non-breathable garments
     –   Replace body fluids as they are lost
     –   Record daily body weight
     –   Air movement is critical for adequate cooling
Heat Index
Exercising in the Cold
•   The excessive loss of body heat can lead to a generalized vasoconstriction
    and conditions such as hypothermia, frostbite, and increased blood
    pressure.
•   Strong wind can accelerate heat loss.
     – The windchill index, which is presented on the following next, provides guidelines
       for determining if exercise is safe.
•   Tips to consider before exercising in the cold:
     – Wear several layers so that garments can be removed or replaced as needed
     – Allow for adequate ventilation of sweat
     – Wear garments made of materials that allow the body to give off body heat
       during exercise and retain body heat during inactivity
     – Replace body fluids in the cold, just as in the heat
     – Monitor body weight over several days
Windchill Factor Chart
Altitude
• 1) Since there is less partial pressure of O2 at
  higher altitudes, HR and respiratory rate
  increase
• 2) During exercise HR may increase up to 50%
      higher than normal
• 3) Decrease exercise pace so the client can
  complete the session without becoming
  exhausted
• 4) It can take up to 2–5 weeks to acclimate to a
      new altitude
Exercising at Higher Altitudes
• At moderate-to-high altitudes, the partial pressure of
  oxygen in the air is reduced.
• Acclimatization (physiological adaptation to an unfamiliar
  or unaccustomed environment) begins in a couple
  weeks, but it may take several months to fully
  acclimatize.
   – Gradually increase exercise intensity over several
     days
   – Increase warm-up and cool-down periods
   – Take frequent exercise breaks at a lower intensity
Altitude Sickness
• The higher the altitude, the greater the risk.
• Altitude sickness can be avoided by proper
  acclimatization.
• Signs and symptoms of altitude sickness include:
   – Shortness of breath
   – Headache
   – Lightheadedness
   – Nausea
Exercising in Air Pollution

• Inhaled air pollutants (i.e., smog) negatively
  affect the body and performance.
• The overall physiological effects depend on the
  amount of pollutant in the air, the length of
  exposure, and the amount of air breathed.
• Exercising early in the morning and avoiding
  high-traffic areas can help minimize exposure.
Age
• Generally, exercise performance improves from puberty
  until young adulthood, followed by a slow decline.
   – If a person maintains activity levels, performance can
     be preserved into the early 30s, but inevitably
     declines beyond age 60.
   – Individuals who are sedentary and over the age of 45
     (for males) and 55 (for females) should avoid high-
     intensity activity the first several weeks to decrease
     the risk of triggering a heart attack.
Gender
• The relative amounts of testosterone (in males)
  and estrogen (in females) account for specific
  variances in males and females and their
  physiological response to exercise.
• Outside of the hormone-attributed differences,
  men and women have very similar responses to
  exercise.
Pregnancy
• Outside of weight gain, change in body shape, and the
  diversion of part of the cardiac output to the developing
  baby, pregnancy has minimal effect on exercise
  performance.
   – Exercise performance will decrease as the pregnancy
       progresses. However, exercise intensity and duration
       should be reduced to maintenance levels during
       pregnancy, as guided by comfort.
        • Current research does not support the traditional
          concerns about hyperthermia and circulatory
          diversion.
• It is not recommended to engage in intense training or
  competitions or to reduce body fat during pregnancy.
General Adaptation Syndrome
•   General adaptation syndrome refers to the body’s predictable
    response to stressful events (including heavy exercise).
•   Three stages
    – Shock or alarm phase (usually lasts 2 to 3 weeks)
        • The individual initially exhibits signs of fatigue, weakness, and soreness.
        • He or she soon experiences remarkable gains (attributed to neuromuscular
          adaptations).
    – Adaptation or resistance phase (begins around weeks 4 to 6)
        • Major muscular adaptations (biochemical, mechanical, and structural)
        • Progressive increases in muscle size and strength
    – Exhaustion phase (may occur at any time)
        • Symptoms similar to the first phase, but inadequate repair or recovery time
          lead to burnout, overtraining, reduction or elimination of overload, injury,
          illness, or lack of adherence
Overtraining
•   Overtraining often occurs during periods of intense overload in which signs
    and symptoms are individualized and include a combination of both
    physiological and emotional factors.
•   Some signs and symptoms include:
     – A decline in physical performance with continued training
     – Elevated heart rate and blood lactate levels at a fixed submaximal work rate
     – Weight loss
     – Sleep disturbance
     – Multiple colds or sore throats
     – Irritability, restlessness, excitability,                                  and/or
       anxiousness
     – Loss of motivation and vigor
     – Lack of mental concentration and focus
     – Lack of appreciation for things that are normally enjoyable
•   The best way to prevent overtraining is periodization.
Delayed Onset Muscle Soreness (DOMS)
•   Research suggests DOMS is caused by tissue injury from excessive
    mechanical force, particularly eccentric force, exerted on muscle
    and connective tissue.
    – Generally appears 24–48 hours after strenuous exercise
    – Is thought to result from a series of events activated by strenuous exercise:
        • First, structural damage occurs as a result of strenuous eccentric muscle
           actions.
        • As a result, calcium is leaked out of the sarcoplasmic reticulum and collects
           in the mitochondria, halting ATP production.
        • The build-up of calcium activates enzymes that break down proteins.
        • The breakdown of proteins causes an inflammatory process.
        • Lastly, the accumulation of histamines, potassium, prostaglandins and
           edema stimulates pain receptors, leading to the sensation of DOMS.
    – Attempt to reduce DOMS by starting at a low intensity and progressing slowly
      through the first few weeks while minimizing eccentric actions.
General Training Principles
•   Principle of specificity
     – The exercise response to any training program is specific to the mode
       and intensity of training.
•   Principles of overload and progression
     – Overload involves increasing the load on the tissue or system above
       and beyond the normal load.
     – Progression is the systematic process of applying overload.
General Training Principles (cont.)
•   Principle of diminishing returns
     – The rate of fitness improvement
       diminishes over time as an individual’s
       fitness approaches its ultimate genetic
                                  potential.
•   Principle of reversibility
     – When training ceases, all gains will
       return
       to pre-training levels and may possibly
       decrease to the point where they are
       only supporting the demands of daily
       use.

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Exercise phys updated

  • 2. Fitness • A. Being active improves health: 30 minutes of accumulated physical activity on most days of the week • B. Being “fit” goes beyond health and requires a comprehensive exercise program that includes the following components • 1) Cardiorespiratory endurance • 2) Muscular strength and endurance • 3) Flexibility • 4) Body composition • 5) Balance
  • 3. Components of Fitness • 1) Cardiorespiratory endurance – The ability to perform large muscle movements over a sustained period • 2a) Muscular strength – The max force that a muscle can produce against a resistance in a single maximal effort. • 2b) Endurance – The capacity of a muscle to exert force repeatedly against a resistance
  • 4. Components of Fitness • 3) Flexibility – The range of motion around a joint • 4) Body composition – The make-up of the body in terms of the relative percentage of fat free mass and body fat • 5) Balance – The ability to maintain the body’s position over it’s base of support.
  • 5. The 5 Fitness Components  Supply the body With O2  Involves the heart. Lungs, & and remove wastes blood vessels  Ability of a muscle or group of muscles to exert maximal  Ratio of lean body mass (muscles, force against a resistance tendons, organs, bone, etc.) to  1 rep max (how much weight fat mass you can lift on one repetition)  What is your % body fat  Ability of a muscle, or group of  Ability of a joint and surrounding muscles to move freely through muscles to exert force over a period of time against a resistance that is less its Range of Motion (ROM)  How far can your muscle move than max  How many times can you lift 80% of your max during stretches
  • 6. Physiology of the Cardiorespiratory System • For muscles to contract, they need energy in the form of ATP. The cardiorespiratory system is responsible for the three basic processes to produce this energy: – Get oxygen into the blood (oxygen-carrying capacity) – Deliver oxygen to the muscles (oxygen delivery) – Extract the oxygen from the blood to form ATP (oxygen extraction) • Oxygen-carrying capacity is affected by two primary functions: (1) the ability to adequately ventilate the alveoli in the lungs and (2) hemoglobin concentration in the blood.
  • 7. Basic Processes Blood Delivery and Nutrient Exchange • 1) Pulmonary Ventilation – The total volume of gas inspired and expired per minute • 2) Cardiac Output – The amount of blood pumped by the heart per minute – HR x SV • 3) Oxygen Extraction – The amount of O2 taken from the HB Molecule and used in the exercising muscle.
  • 8. Oxygen Delivery • Oxygen delivery is a function of cardiac output (the quantity of blood pumped per minute). – Cardiac output (Q) = Stroke volume (SV) x Heart rate (HR) (in beats per min) • Stroke volume is the amount of blood pumped during each heartbeat. – Cardiac output increases due to increases in both SV and HR. • HR typically increases in a linear fashion up to maximal levels. • SV increases to about 40–50% of maximal capacity, and then plateaus.
  • 9. Oxygen Extraction • Oxygen extraction from the blood at the cellular level depends on muscle fiber type and the availability of specialized oxidative enzymes. – Slow-twitch muscle fibers are specifically adapted for oxygen extraction and utilization. – Aerobic production of ATP occurs in the mitochondria of the cells. – The circulatory system increases blood flow to the active muscles and decreases blood flow to non- active areas such as the viscera, allowing a higher concentration of O2 to be extracted.
  • 10. Oxygen Consumption • The more oxygen a person can take in, deliver, and utilize, the more work he or she can perform. • VO2max refers to one’s maximal oxygen consumption. – It is expressed in either “relative” terms (mL/kg/min) or “absolute” terms (L/min). – Relative VO2max allows comparisons between individuals. Absolute VO2max is used to determine caloric expenditure during specific activities. • Approximately 5 kcal of energy are burned for every liter of oxygen consumed.
  • 11. Energy production • 1) Adenosine triphosphate (ATP) • a.Manufactured by the mitochondria in the muscle cell • b. ATP is the energy source used to drive muscle contraction • c. Fatty acids and glucose are used to produce ATP • d. Amino acids are not a preferred energy source, but are used in an undernourished individual
  • 12. Energy production Energy System Substrate Limitation to Produce Primary Use ATP ANAEROBIC Phosphogen Creatine Muscle stores very little CP High-intensity, short- phosphate (CP) and ATP duration activities; Stored ATP less than 10 seconds to fatigue Anaerobic Glucose and Lactic acid build-up causes High-intensity, short- glycolysis glycogen rapid fatigue duration activities; from 1–3 minutes to fatigue AEROBIC Fatty acids, Depletion of muscle Long-duration, sub- glucose, and glycogen; insufficient O2 anaerobic threshold glycogen delivery activities; longer than 3 minutes to fatigue
  • 13. Anaerobic Threshold • The anaerobic threshold (AT) is reached when exercise intensity increases above steady-state aerobic metabolism and anaerobic production of ATP occurs. • When the AT is crossed, exercise can only be sustained for a few minutes before hyperventilation begins to occur. – Lactate accumulates progressively in the blood and the oxygen deficit and corresponding EPOC are extremely high. – At this point, the body attempts to rid excess CO 2 (a by-product of acid metabolites). The increase in respiration is called the second ventilatory threshold (VT2). – VT2 is an indirect indicator of AT.
  • 14. Ventilatory Threshold • There are two distinct changes in breathing patterns during incremental exercise: the first ventilatory threshold (VT1) and the second ventilatory threshold (VT2). • VT1 occurs as soon as blood lactate begins to accumulate and the body needs to rid itself of excess CO2 through increased respiration. – Can be identified using the “talk test.” It is the first point at which it becomes noticeably more difficult to speak. • VT2 occurs as blood lactate rapidly increases with intensity, and represents increased hyperventilation past the need to rid the body of excess CO2. – Also known as lactate threshold (LT) and respiratory compensation threshold (RCT) – Speaking is definitely not comfortable at this intensity.
  • 15. Fuel Use During Exercise: Carbohydrates • Carbohydrates are the major food macronutrient for the metabolic production of adenosine triphosphate (ATP) and the only one whose stored energy can produce ATP anaerobically. – Stored as glycogen in the muscle and liver • Glycogenolysis (breakdown of liver glycogen to glucose) is the primary regulator of blood glucose. – Carbohydrates used during exercise come from both glycogen stores in muscle tissue and blood glucose. • The relative contribution of muscle glycogen and blood glucose used during exercise is determined by intensity and duration. • After the first hour of submaximal exercise, carbohydrate metabolism shifts from muscle glycogen to glycogenolysis in the liver.
  • 16. Fuel Use During Exercise: Fats • Fats are mainly stored as triglycerides in adipocytes, which must be broken down into FFAs and glycerol. – During low-intensity exercise, circulating FFAs from adipocytes are the primary energy source from fat, but during higher intensities, muscle triglyceride metabolism increases. – As duration increases, the role of plasma FFAs as a fuel source increases.
  • 17. Fuel Use During Exercise: Protein • Protein plays a small role in the fueling of exercise. It must be broken down into amino acids, which can be supplied to the muscle tissue from the blood and from the muscle fiber itself. – Skeletal muscle can directly metabolize certain amino acids to produce ATP. – During exercise, glucose stored in a non-exercising muscle can be delivered indirectly to the exercising muscle via the glucose-alanine pathway.
  • 18. Cardiorespiratory adaptations to acute aerobic exercise • 1) Increased heart rate (HR) • 2) Increased stroke volume (SV) • a.The amount of blood pumped from each ventricle each time the heart beats • b.Measured in mL per beat • Cardiac output = HR x SV
  • 19. Cardiorespiratory adaptations to acute aerobic exercise • 3) Increased cardiac output • a. Cardiac output = HR x SV • b. A typical cardiac output at rest: • 60 bpm x 70 mL/beat = 4200 mL/min • (approximately 1 gallon of blood per min) • 4) Increased breathing rate
  • 20. Cardiorespiratory adaptations to acute aerobic exercise • 5) Increased systolic blood pressure • a. Due to the cardiovascular system attempting to increase O2 delivery to the muscles • b. However, blood pressure greater than 250/115 mmHg is an indication to terminate exercise (hypertensive response)
  • 21. Cardiorespiratory adaptations to acute aerobic exercise • 6) No change (or a slight decrease) in diastolic blood pressure • a. Due to the dilation of vessels in the muscles and the skin • b. This decreases peripheral resistance (which is an important benefit for individuals suffering from heart disease, hypertension, diabetes, and peripheral vascular disease)
  • 22. Blood Pressure During Exercise • Systolic blood pressure has a much higher increase during exercise than diastolic blood pressure due to: – Increased contractility of the heart – Increased stroke volume – The muscular need for greater force and pressure to deliver blood to the exercising muscles – Vasodilation within the exercising muscle, which results in more blood draining from the arteries, through the arterioles, and into muscle capillaries, minimizing the change in diastolic pressure
  • 23. Cardiorespiratory adaptations to acute aerobic exercise • 7) Blood is shunted from the viscera to the working muscles • a. Dilation of vessels that supply blood to the exercising muscles • b. Constriction of vessels that supply blood to the abdominal area
  • 24. Cardiorespiratory adaptations to acute aerobic exercise • 8) Increased extraction of oxygen from the blood into the working tissues • a. A normal, healthy person is able to load the blood with more O2 in the lungs than he or she is able to use at the cellular level • b. Therefore, the more efficiently an individual can extract O2 from the hemoglobin in the capillaries, the more fit he or she becomes
  • 25. Chronic Training Adaptations to Exercise  SAID principle (specific adaptation to imposed demands)  Examples include: – Improved cardiac output efficiency (increased SV and lower HR) (aerobic training) – Increase in respiratory capacity (aerobic training) – Increase in maximal oxygen consumption (aerobic training) – Increase in bone density (weightbearing exercise) – Improved control of blood glucose and lipids (physical activity) – Maintained or improved lean body mass (weightbearing activity) – Decreased depression and anxiety (physical activity) – Higher quality of life (physical activity)
  • 26. Cardiorespiratory adaptations due to regular aerobic exercise • 1) Decreased RHR • a. With consistent exercise (as few as three months of regular aerobic training), the interior dimensions of the ventricles increase, allowing them to hold more blood • b. The same cardiac output can be maintained at a lower HR due to the greater SV
  • 27. Cardiorespiratory adaptations due to regular aerobic exercise • 2) Decreased relative working heart rate • a. Since a given intensity requires a given amount of O2, HR at any given intensity will be lower due to increased SV • b. A trained individual will have to work at higher intensities to achieve the same HR he or she achieved prior to being fit
  • 28. Cardiorespiratory adaptations due to regular aerobic exercise • 3) Increased VO2max as SV increases • a. VO2max is the total capacity to consume oxygen at the cellular level • b. VO2max depends on two factors • 1. The delivery of O2 to the working muscle by the blood (cardiac output) • 2. The ability to extract the O2 at the capillaries and use it in the mitochondria
  • 29. Cardiorespiratory adaptations due to regular aerobic exercise • 4) Increased O2 extraction • a. Improved ability to remain “aerobic” at higher intensities • b. Increased capillary density • c. Increased mitochondrial density • d. Increased ability to create ATP
  • 30. Cardiorespiratory adaptations due to regular aerobic exercise • 5) Increased fatty acid oxidation at any submaximal intensity • 6) More glycogen is stored in trained muscles and less lactic acid is produced • 7) Increased tolerance to lactic acid produced during exercise
  • 31. Exercising in the Heat • In addition to exercising in a hot, humid environment, other factors can cause heat overload. – Poor hydration prior to exercise – Overdressing – Overweight and obesity • During exercise, the internal heat load is brought to the skin’s surface to be cooled via the secretion of water by the sweat glands (evaporation). – The goal (given favorable environmental conditions) is to prevent body temperature from rising more than 2 to 3°F. – When the ability to dissipate heat is compromised, injuries occur.
  • 32. Physiological Responses to Exercising in the Heat • Dissipating internal body heat is more difficult in the heat, resulting in a higher heart rate than normal at any level of exercise to maintain cardiac output. • A hot humid environment is the most stressful environment for exercising and poses the risk of heat exhaustion and heat stroke.
  • 33. Safety in the Heat • The heat index, as presented on the next slide, provides guidelines on when exercise is safe and when it should be avoided. • Tips to consider before exercising in the heat: – Begin gradually – Always wear lightweight, well-ventilated clothing – Avoid impermeable or non-breathable garments – Replace body fluids as they are lost – Record daily body weight – Air movement is critical for adequate cooling
  • 35. Exercising in the Cold • The excessive loss of body heat can lead to a generalized vasoconstriction and conditions such as hypothermia, frostbite, and increased blood pressure. • Strong wind can accelerate heat loss. – The windchill index, which is presented on the following next, provides guidelines for determining if exercise is safe. • Tips to consider before exercising in the cold: – Wear several layers so that garments can be removed or replaced as needed – Allow for adequate ventilation of sweat – Wear garments made of materials that allow the body to give off body heat during exercise and retain body heat during inactivity – Replace body fluids in the cold, just as in the heat – Monitor body weight over several days
  • 37. Altitude • 1) Since there is less partial pressure of O2 at higher altitudes, HR and respiratory rate increase • 2) During exercise HR may increase up to 50% higher than normal • 3) Decrease exercise pace so the client can complete the session without becoming exhausted • 4) It can take up to 2–5 weeks to acclimate to a new altitude
  • 38. Exercising at Higher Altitudes • At moderate-to-high altitudes, the partial pressure of oxygen in the air is reduced. • Acclimatization (physiological adaptation to an unfamiliar or unaccustomed environment) begins in a couple weeks, but it may take several months to fully acclimatize. – Gradually increase exercise intensity over several days – Increase warm-up and cool-down periods – Take frequent exercise breaks at a lower intensity
  • 39. Altitude Sickness • The higher the altitude, the greater the risk. • Altitude sickness can be avoided by proper acclimatization. • Signs and symptoms of altitude sickness include: – Shortness of breath – Headache – Lightheadedness – Nausea
  • 40. Exercising in Air Pollution • Inhaled air pollutants (i.e., smog) negatively affect the body and performance. • The overall physiological effects depend on the amount of pollutant in the air, the length of exposure, and the amount of air breathed. • Exercising early in the morning and avoiding high-traffic areas can help minimize exposure.
  • 41. Age • Generally, exercise performance improves from puberty until young adulthood, followed by a slow decline. – If a person maintains activity levels, performance can be preserved into the early 30s, but inevitably declines beyond age 60. – Individuals who are sedentary and over the age of 45 (for males) and 55 (for females) should avoid high- intensity activity the first several weeks to decrease the risk of triggering a heart attack.
  • 42. Gender • The relative amounts of testosterone (in males) and estrogen (in females) account for specific variances in males and females and their physiological response to exercise. • Outside of the hormone-attributed differences, men and women have very similar responses to exercise.
  • 43. Pregnancy • Outside of weight gain, change in body shape, and the diversion of part of the cardiac output to the developing baby, pregnancy has minimal effect on exercise performance. – Exercise performance will decrease as the pregnancy progresses. However, exercise intensity and duration should be reduced to maintenance levels during pregnancy, as guided by comfort. • Current research does not support the traditional concerns about hyperthermia and circulatory diversion. • It is not recommended to engage in intense training or competitions or to reduce body fat during pregnancy.
  • 44. General Adaptation Syndrome • General adaptation syndrome refers to the body’s predictable response to stressful events (including heavy exercise). • Three stages – Shock or alarm phase (usually lasts 2 to 3 weeks) • The individual initially exhibits signs of fatigue, weakness, and soreness. • He or she soon experiences remarkable gains (attributed to neuromuscular adaptations). – Adaptation or resistance phase (begins around weeks 4 to 6) • Major muscular adaptations (biochemical, mechanical, and structural) • Progressive increases in muscle size and strength – Exhaustion phase (may occur at any time) • Symptoms similar to the first phase, but inadequate repair or recovery time lead to burnout, overtraining, reduction or elimination of overload, injury, illness, or lack of adherence
  • 45. Overtraining • Overtraining often occurs during periods of intense overload in which signs and symptoms are individualized and include a combination of both physiological and emotional factors. • Some signs and symptoms include: – A decline in physical performance with continued training – Elevated heart rate and blood lactate levels at a fixed submaximal work rate – Weight loss – Sleep disturbance – Multiple colds or sore throats – Irritability, restlessness, excitability, and/or anxiousness – Loss of motivation and vigor – Lack of mental concentration and focus – Lack of appreciation for things that are normally enjoyable • The best way to prevent overtraining is periodization.
  • 46. Delayed Onset Muscle Soreness (DOMS) • Research suggests DOMS is caused by tissue injury from excessive mechanical force, particularly eccentric force, exerted on muscle and connective tissue. – Generally appears 24–48 hours after strenuous exercise – Is thought to result from a series of events activated by strenuous exercise: • First, structural damage occurs as a result of strenuous eccentric muscle actions. • As a result, calcium is leaked out of the sarcoplasmic reticulum and collects in the mitochondria, halting ATP production. • The build-up of calcium activates enzymes that break down proteins. • The breakdown of proteins causes an inflammatory process. • Lastly, the accumulation of histamines, potassium, prostaglandins and edema stimulates pain receptors, leading to the sensation of DOMS. – Attempt to reduce DOMS by starting at a low intensity and progressing slowly through the first few weeks while minimizing eccentric actions.
  • 47. General Training Principles • Principle of specificity – The exercise response to any training program is specific to the mode and intensity of training. • Principles of overload and progression – Overload involves increasing the load on the tissue or system above and beyond the normal load. – Progression is the systematic process of applying overload.
  • 48. General Training Principles (cont.) • Principle of diminishing returns – The rate of fitness improvement diminishes over time as an individual’s fitness approaches its ultimate genetic potential. • Principle of reversibility – When training ceases, all gains will return to pre-training levels and may possibly decrease to the point where they are only supporting the demands of daily use.