Evidence based practice involves making clinical decisions based on the best available research evidence, combined with clinical expertise and patient values. It aims to provide the highest quality and most cost effective care. Several models of evidence based practice exist, including the Stetler model, IOWA model, and Rossworn and Larrabee model, which provide frameworks for finding, evaluating, and applying research evidence to practice to improve patient outcomes. Barriers to evidence based practice include lack of research knowledge and skills among nurses as well as lack of time and support for incorporating research into care.