This document evaluates the results of 18F-FDG PET/CT for cancer diseases at Da Nang Hospital from 2014 to 2017. It finds that over 2,500 PET/CT scans were performed, most commonly for lung cancer, breast cancer, and lymphoma. The main purposes of the scans were for staging before treatment and evaluating treatment response. PET/CT led to changes in staging for 43.3% of cases and changes in treatment strategy for 14.68% of cases. The conclusion is that PET/CT at Da Nang Hospital has helped improve diagnosis, treatment, and follow-up for cancer patients.
Find the best doctor of PET CT Scan in Pune at Onco Life Cancer Centre, Satara.
For more info, please visit: https://www.oncolifehospitals.com/services/pet-ct-scan/
Find the best doctor of PET CT Scan in Pune at Onco Life Cancer Centre, Satara.
For more info, please visit: https://www.oncolifehospitals.com/services/pet-ct-scan/
USE OF PET – HEALTH CARE POLICY PERSPECTIVESRuby Med Plus
POSITRON EMISSION TOMOGRAPHY (PET) USE BY TERTIARY HEALTH CARE CENT RES AND ITS ACCESSIBILITY TO POPULATION: A POLICY PERSPECTIVE. a BRIEF Cost-Benefit analysis.
Virtual Navigator Real-Time Ultrasound Fusion Imaging with Positron Emission ...rosopeplaton
Enzo Di Mauro, Marco Solbiati, Stefano De Beni, Leonardo Forzoni, Sara D’Onofrio, Luigi Solbiati
Real-time fusion imaging technologies are
increasingly being used among interventional radiologists,
mostly Computed Tomography (CT) or Magnetic Resonance
Imaging (MRI) dataset, fused with Ultrasound (US) imaging. In
addition, fusion of Positron Emission Tomography (PET) and
CT is increasingly diffused in clinical practice, due to the wide
availability of PET scanners and the capability to make either a
direct (acquisitions performed within the same system) or an
indirect (procedure performed on an external workstation,
merging the two different sets of acquired data) fusion with CT
data. The present work describes the feasibility of real-time
fusion imaging directly between PET data and US imaging,
with CT scans being used only for PET-US fusion registration.
Data on multimodality registration precision and clinical
applications are presented as well.
Angiogenic blockade and Tomotherapy in hepatocellular carcinomaaccurayexchange
季匡華 Kwan-Hwa Chi, M.D.
Chairman, Section of Radiation Therapy and Oncology Shin Kong Wu Ho-Su Memorial Hospital, Taiwan Professor, School of Medicine
National Yang-Ming University
Co-relation of multidetector CT scan based preoperative staging with intra-op...Apollo Hospitals
To assess the accuracy of CT scan in preoperative staging, to correlate preoperative findings with operative findings and with post-operative histopathological findings of colorectal carcinoma.
The utility of 18F-fluorocholine PET/CT in the imaging of parathyroid adenomasNukleer Tıp Uzmanı
Introduction:
The aim of the study was to estimate the sensitivity of 18F-FCH PET/CT in preoperative localisation of hyperfunctioning parathyroid glands in patients with primary hyperparathyroidism (PHPT).
Material and methods:
Sixty-five consecutive patients with PHPT, who underwent neck ultrasound (US) and 99mTc/99mTc-MIBI dual-phase parathyroid scintigraphy, were prospectively enrolled. Twenty-two patients had unsuccessful parathyroid surgery prior to the study. PET/CT scans were performed 65.0 ± 13.3 min after injection of 218.5 ± 31.9 MBq of 18F-fluorocholine (FCH). Three experienced nuclear medicine physicians assessed the detection rate of hyperfunctioning parathyroid tissue. Response to parathyroidectomy and clinical follow-up served as a reference test. Per-patient sensitivity and positive predictive value (PPV) were calculated for patients who underwent surgery.
Results:
18F-FCH PET/CT was positive in 61 patients, and negative in 4. US and parathyroid scintigraphy showed positive and negative results in 20, 45 and 17, 48, respectively. US showed nodular goitre in 31 patients and chronic thyroiditis in 9 patients. Parathyroid surgery was performed in 43 (66%) patients. 18F-FCH PET/CT yielded a sensitivity of 100% (95% CI: 87.99–100) and PPV of 85.7% (95% CI: 70.77–94.06). Similar values were observed in patients with chronic thyroiditis, nodular goitre, and patients after an unsuccessful parathyroid surgery. PET/CT identified hyperparathyroidism complications (kidney stones, osteoporotic bone fractures, and brown tumours) in 11 patients.
Conclusions:
18F-FCH PET/CT effectively detected hyperfunctioning parathyroid tissue and its complications. The method showed excellent sensitivity and positive predictive value, including patients with nodular goitre, chronic thyroiditis, and prior unsuccessful parathyroidectomy. PET/CT performance was superior to neck ultrasound and parathyroid scintigraphy.
18F-FCH PET/CT; fluorocholine; hyperparathyroidism; parathyroid imaging
USE OF PET – HEALTH CARE POLICY PERSPECTIVESRuby Med Plus
POSITRON EMISSION TOMOGRAPHY (PET) USE BY TERTIARY HEALTH CARE CENT RES AND ITS ACCESSIBILITY TO POPULATION: A POLICY PERSPECTIVE. a BRIEF Cost-Benefit analysis.
Virtual Navigator Real-Time Ultrasound Fusion Imaging with Positron Emission ...rosopeplaton
Enzo Di Mauro, Marco Solbiati, Stefano De Beni, Leonardo Forzoni, Sara D’Onofrio, Luigi Solbiati
Real-time fusion imaging technologies are
increasingly being used among interventional radiologists,
mostly Computed Tomography (CT) or Magnetic Resonance
Imaging (MRI) dataset, fused with Ultrasound (US) imaging. In
addition, fusion of Positron Emission Tomography (PET) and
CT is increasingly diffused in clinical practice, due to the wide
availability of PET scanners and the capability to make either a
direct (acquisitions performed within the same system) or an
indirect (procedure performed on an external workstation,
merging the two different sets of acquired data) fusion with CT
data. The present work describes the feasibility of real-time
fusion imaging directly between PET data and US imaging,
with CT scans being used only for PET-US fusion registration.
Data on multimodality registration precision and clinical
applications are presented as well.
Angiogenic blockade and Tomotherapy in hepatocellular carcinomaaccurayexchange
季匡華 Kwan-Hwa Chi, M.D.
Chairman, Section of Radiation Therapy and Oncology Shin Kong Wu Ho-Su Memorial Hospital, Taiwan Professor, School of Medicine
National Yang-Ming University
Co-relation of multidetector CT scan based preoperative staging with intra-op...Apollo Hospitals
To assess the accuracy of CT scan in preoperative staging, to correlate preoperative findings with operative findings and with post-operative histopathological findings of colorectal carcinoma.
The utility of 18F-fluorocholine PET/CT in the imaging of parathyroid adenomasNukleer Tıp Uzmanı
Introduction:
The aim of the study was to estimate the sensitivity of 18F-FCH PET/CT in preoperative localisation of hyperfunctioning parathyroid glands in patients with primary hyperparathyroidism (PHPT).
Material and methods:
Sixty-five consecutive patients with PHPT, who underwent neck ultrasound (US) and 99mTc/99mTc-MIBI dual-phase parathyroid scintigraphy, were prospectively enrolled. Twenty-two patients had unsuccessful parathyroid surgery prior to the study. PET/CT scans were performed 65.0 ± 13.3 min after injection of 218.5 ± 31.9 MBq of 18F-fluorocholine (FCH). Three experienced nuclear medicine physicians assessed the detection rate of hyperfunctioning parathyroid tissue. Response to parathyroidectomy and clinical follow-up served as a reference test. Per-patient sensitivity and positive predictive value (PPV) were calculated for patients who underwent surgery.
Results:
18F-FCH PET/CT was positive in 61 patients, and negative in 4. US and parathyroid scintigraphy showed positive and negative results in 20, 45 and 17, 48, respectively. US showed nodular goitre in 31 patients and chronic thyroiditis in 9 patients. Parathyroid surgery was performed in 43 (66%) patients. 18F-FCH PET/CT yielded a sensitivity of 100% (95% CI: 87.99–100) and PPV of 85.7% (95% CI: 70.77–94.06). Similar values were observed in patients with chronic thyroiditis, nodular goitre, and patients after an unsuccessful parathyroid surgery. PET/CT identified hyperparathyroidism complications (kidney stones, osteoporotic bone fractures, and brown tumours) in 11 patients.
Conclusions:
18F-FCH PET/CT effectively detected hyperfunctioning parathyroid tissue and its complications. The method showed excellent sensitivity and positive predictive value, including patients with nodular goitre, chronic thyroiditis, and prior unsuccessful parathyroidectomy. PET/CT performance was superior to neck ultrasound and parathyroid scintigraphy.
18F-FCH PET/CT; fluorocholine; hyperparathyroidism; parathyroid imaging
First of its kind in South India GE IQ PET/CT at MIOT HospitalsMIOT Hospitals
The GE IQ PET/CT at MIOT International (1st of its kind in South India) offers Superior Image Quality and Intelligent Quantitation enabling the Physician to discover and diagnose cancer confidently. Now, we can detect even minute abnormalities and offer accurate diagnoses and monitoring to our patients.
A CT-Based Nomogram for Preoperative Prediction of Synchronous Peritoneal Met...daranisaha
Colorectal Cancer (CRC) is the third most common cancer with estimated 1000,000 of new cases worldwide each year, ranking the third cause of cancer-related death [1]. Peritoneal Metastasis (PM) is considered to be a terminal stage of CRC metastasis with unfavorable fatal outcome [2, 3]. The incidence of synchronous PM is about 5-10% of CRC at the initial diagnosis, while 5% of PM are presented with metachronous PM after radical resection, and approximately 25-44% of patients occur in recurrent disease [2]. Recently, Cytoreductive Surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) become popular options and are widely adopted for treating PM in many centers worldwide and the median OS increase to 42 months with this treatment [2,4,5].
Early diagnosis of synchronous PM with a Peritoneal Cancer Index (PCI) < 20 points, can increase the probability of complete CRS procedure [2, 4]. If CRS is incomplete, namely palliative surgery in late-stage PM, the median OS is less than 10 months [2, 6]. Palliative surgery comes with high mortality and substantial hospitalizations and limited survival, especially those with poor prognostic features like ascites or palpable masses with a median survival of 36 days, while early PM with favorable prognostic features obtained a median survival of 154 days
Basem AL Al Zahrany
How effective is CT Colonography in detecting colon cancer?
Introduction
The second cause leading to death in the United States is colorectal cancer in the same way colorectal cancer is the third common cancer in women and men. In the United States 135,260 people diagnosed with colorectal cancer in 2011. Colorectal cancer caused for 51,783 people from them the death. The number of colorectal cancer patients is predictable to rise in the future. Built on the present data, cost scenario and survival for colorectal cancer Yabroff et al expected the cost effect in 2020 for the primary $4.05 billion, making a significant cost load on the healthcare system. Colorectal cancer mortality was decreased by 18% to13 % with apply CT Colonography to detect colonic polyps before they developed to colorectal cancer (Trilisky et al, 2015). CT Colonography has been shown to have polyp discovery rates similar to the patient how use colonoscopy. CT Colonography is an exam for colorectal cancer screening which became generally effected for detecting polyps similar to those of colonoscopy. It has the prospective to improve colorectal cancer screening rates because of colorectal is come to be insignificant noninvasive ,faster patient in quantity ,no sedation requirement and potential for reduced cathartic examination . Appropriate program of a CT Colonography screening must implement and needs important announce to several aspects, counting proper patient preparation before the investigation, image acquisition, and post-processing of the developed images. A CT Colonography need workstation with special software and high quality monitors. Special software called Computer-Aided Detection CAD which is manipulate to reduce mistakes of spotting and showing polyps to the radiologist for images interpretation. These essay will discuss technique, advantages , disadvantages of CT Colonography and how CT Colonography can be affect for colorectal cancer .
Exam technique
Currently, patients go through intestine preparation procedure which has the purpose of avoid misdiagnosed of polyps by cleaning the colon. So far there is no agreement on a best program of food adjustment and releasing preparation of flexible period and amount. There is continuing studies aimed to rise patient relaxation and acceptance. To distinguish polyps from other residual the use usually fecal and fluid tagging with bowel laxative. Some time they do it with small quantity of both iodine-based contrast material and barium or one of them to improve the image and to eliminate the artifact of image which could be accrue ,which may rise the sensitivity of polyp detection, Digital subtraction is a post-acquisition processing technique use to improve the image quality(Trilisky,2015).
Advantages of CT Colonography
CT Colonography shows high sensitivit ...
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Evaluation the Results of 18F-FDG PET/CT Implementation for Cancer Diseases at Da Nang Hospital from 2014 to 2017
1. Evaluation the ResultsEvaluation the Results of 18F-FDG PET/CTof 18F-FDG PET/CT
Implementation for Cancer Diseases at Da NangImplementation for Cancer Diseases at Da Nang
Hospital from 2014 to 2017Hospital from 2014 to 2017
NGUYỄN VĂN MINHNGUYỄN VĂN MINH
Nuclear Medicine DepartmentNuclear Medicine Department
Da Nang HospitalDa Nang Hospital
2. ► PET-CT: Nuclear Imaging technique combinePET-CT: Nuclear Imaging technique combine
Positron Emission Tomography (PET)Positron Emission Tomography (PET)
Computed Tomography (CT)Computed Tomography (CT)
► Fused image:Fused image:
Functional imaging obtained by PET + Anatomic imagingFunctional imaging obtained by PET + Anatomic imaging
obtained by CT.obtained by CT.
PET-CT : detect and locate lesions in one examinationPET-CT : detect and locate lesions in one examination
What’s PET-CT?
5. ► To diagnose diseases : in cardiology, in neurology andTo diagnose diseases : in cardiology, in neurology and
especially in oncology.especially in oncology.
► In oncology:In oncology:
To diagnose cancer and stage of cancerTo diagnose cancer and stage of cancer
To choose treatment strategy.To choose treatment strategy.
To evaluate the effective of treatment.To evaluate the effective of treatment.
To follow cancer recurrenceTo follow cancer recurrence
PET-CT APPLICATION
6. 108 Hospital
Bach Mai Hospital
Viet Duc Hospital
Cho Ray Hospital
175 Hospital
115 Hospital
Da Nang Hospital
PET-CT
in Viet Nam
7. PET-CT at Da Nang HospitalPET-CT at Da Nang Hospital
► Since Sept 8Since Sept 8thth
20142014
► Number of cases: 2570 cases (Sept 2014 to SeptNumber of cases: 2570 cases (Sept 2014 to Sept
2017)2017)
8. PET-CT at Da Nang HospitalPET-CT at Da Nang Hospital
PET-CT DISCOVERY 710, CT16 slices, GEPET-CT DISCOVERY 710, CT16 slices, GE
10. Procedure for PET-CTProcedure for PET-CT
The patient fasts for at least 4 hoursThe patient fasts for at least 4 hours
Clinical examinationClinical examination
Setup an intravenous lineSetup an intravenous line
Injection ofInjection of 1818
F-FDG (dose 0.14mCi/kg)F-FDG (dose 0.14mCi/kg)
11. Procedure for PET-CTProcedure for PET-CT
The patient rests lying in isolation room, quiets downThe patient rests lying in isolation room, quiets down
muscular activitymuscular activity
PET-CT Acquisition after 45-60 min of injectionPET-CT Acquisition after 45-60 min of injection
Image acquisition lasts for about 20minImage acquisition lasts for about 20min
Images were analyzed with PETVCAR software.Images were analyzed with PETVCAR software.
Interpreter.Interpreter.
15. Research SubjectResearch Subject
All patients who had PET-CT acquisitionAll patients who had PET-CT acquisition
at Da Nang Hospital from Sept 2014 to Sept 2017at Da Nang Hospital from Sept 2014 to Sept 2017
16. Research MethodResearch Method
► Research MethodsResearch Methods
Retrospective, Statistical, Descriptive Study.Retrospective, Statistical, Descriptive Study.
► Data Collection MethodsData Collection Methods
Data were collected by clinical examination, sub-clinicalData were collected by clinical examination, sub-clinical
examinations, PET/CT results.examinations, PET/CT results.
► Data Analysis MethodsData Analysis Methods
By Medical Statistical SofwareBy Medical Statistical Sofware
17. Results & Discussion
Table 1. Distribution of patients by ages
Age in years Cases Percentagee%
≤ 10 15 0,58
11-20 41 1,60
21-40 271 10,54
41-60 1217 47,36
61-80 904 35,18
≥ 81 122 4,75
Sum 2570 100
Mai Trong Khoa (2009): 61.2 percent of patients were
aged between 30 and 60 years (reasonable with age
at risk of cancer )
18. Table 2. Distribution of patients by period.
Period Number of cases Percentage(%)
9/2014 - 2/2015 401 15,60
30,35
3/2015 - 8/2015 379 14,75
9/2015 - 2/2016 445 17,31
37,43
3/2016 - 8/2016 517 20,12
9/2016 - 2/2017 420 16,34
32,22
3/2017 - 9/2017 408 15,88
Total 2570 100 100
Number of PET-CT patients increased in 2nd
year (37.43%)
and reduced in 3rd
year (32.22%)
Results & Discussion
19. Table 3. Distribution of patients by hospitals.
Hospital Number of cases Percentage(%)
Hospitals in Da Nang 2264 88,11
Hue Central Hospital 222 8,64
Hue University Hospital 74 2,87
Hospital of Northern Quang Nam 5 0,19
Quang Ngai Hospital 5 0,19
Total 2570 100
• Number of cases from hospitals in Da Nang was 88.11%
• Number of cases from others hospitals increased in time
but still in the low rate.
Results & Discussion
20. Chart 1. Distribution of patients by diagnosis
Common cancer types: lung cancer, breast cancer, colon
cancer, stomach cancer
Results & Discussion
21. Table 4. Distribution of patients by indication purposes
Purpose Number of cases Percentage(%)
Cancer Diagnosis 376 14,64
Detection of unknown original cancer 131 5,11
Staging before treatment 980 38,13
Evaluation of treatment response 35 1,36
Evaluation of post-treatment response 906 35,25
Restaging after treatment 142 5,52
Total 2570 100
Main purposes : Cancer Diagnosis ( 14,64%), Staging before treament
( 38,13%), Evaluation of treatment responde (35,25% )
Results & Discussion
22. Table 6. Location of primary tumors
Location Number of cases Percentage(%)
Lung 41 31,30
Head and neck 32 24,43
Esophagus 8 6,11
Colon 5 3,82
Breast 3 2,28
Not detected 42 32,06
Total 131 100
Lung cancer: 31.3%
Head and neck tumors: 24.43%
Not detected by PET-Ct: 32.06% (according to research of Trong
Khoa MAI
Results & Discussion
24. PET-CT in cancer diagnose : malignant
Patient: Male, 57 years old. Diagnosis: Pancreatic tumors
PET-CT : Lesions at pancreas with high Max SUV + nodal metastases
Max SUV 8,71
Max SUV 9,74
25. PET-CT in cancer diagnose : benign
Patient: Female, 30 years old .Diagnosis: Pancreatic tumors
PET-CT : MaxSUV low maybe benign lesions
26. PETPET-CT diagnoses unknown cause prolonged fever-CT diagnoses unknown cause prolonged fever
Patient: male, 72 years old, unknown cause prolonged feverPatient: male, 72 years old, unknown cause prolonged fever
PET-CT: lymphomaPET-CT: lymphoma
27. PET- CT: unknown original metastasis cancer
Patient: Male, 46 years old, Nodal metastases in thePatient: Male, 46 years old, Nodal metastases in the
neck, Squamous cell carcinomaneck, Squamous cell carcinoma
Nodal
metastases
Clear tumor in
PET CT
Unclear tumor in CT
28. PET-CT for staging before treatment : reduce stage
Patient : male, 66 years old, esophagus cancer,
suspected lung metastasis
29. điều trịđiều trịPET-CT for staging before treatment : Increase stage
Patient: male, 57 years old, Diagnose before PET CT :
Colon cancer T3N1Mx
30. PET-CT for follow-upPET-CT for follow-up
Patient: male, 55 years old, stomach cancer, had surgery,Patient: male, 55 years old, stomach cancer, had surgery,
chemotherapy 1 year agochemotherapy 1 year ago
PET-CTPET-CT nodal metastases at hilum of the livernodal metastases at hilum of the liver
Max SUV = 10,79
31. PET-CT evaluates response of treatment
Patient: male, 53 years old, Lymphoma non hodgkin,
stage IIB, after 3 cycles of chemotherapy.
32. PET-CT evaluates response of treatmentPET-CT evaluates response of treatment
Patient: male, 39years old, lung cancer, brain metastasisPatient: male, 39years old, lung cancer, brain metastasis
PET-CT 2 months after radiotherapyPET-CT 2 months after radiotherapy
Max SUV = 27,25 Max SUV = 12,58
Oct 28th Mar 12th
33. - PET-CT: has run at Da Nang Hospital since Sept 2014, to Sept 2017PET-CT: has run at Da Nang Hospital since Sept 2014, to Sept 2017
number of cases was 2570 .number of cases was 2570 .
- Common cancer types: Lung cancer (26,69%), breast cancer(11,31%),Common cancer types: Lung cancer (26,69%), breast cancer(11,31%),
lymphoma (9,07%), head and neck cancer (6,43%).lymphoma (9,07%), head and neck cancer (6,43%).
- Indication purposes: staging before treatment (38,13%), evaluation ofIndication purposes: staging before treatment (38,13%), evaluation of
response after treatment (35,25%).response after treatment (35,25%).
- PET/CT made changes in staging(43,30%) and made changes inPET/CT made changes in staging(43,30%) and made changes in
treatment strategy (14,68%).treatment strategy (14,68%).
- PET-CT at Da Nang Hospital helps improve diagnosis, treatment, follow-PET-CT at Da Nang Hospital helps improve diagnosis, treatment, follow-
up in cancer patients, also helps patients save time and money.up in cancer patients, also helps patients save time and money.
Conclusion
Editor's Notes
2000: thế hệ PET/CT đầu tiên
2009: về Việt Nam
Từ năm 2000, người ta đã tạo được một tổ hợp PET/Ct dựa vào việc thiết kế phần cứng để kết hợp hình ảnh chuyển hóa trao đổi chất với hình ảnh giải phẫu trong cơ thê