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MIOT Hospitals : 4/112, Mount Poonamallee Road, Manapakkam Chennai - 600089, India
Tel: +91 44 4200 2288, Fax: +91 44 2249 1313 Email: chief@miothospitals.com www.miotinternational.com
w w w . m i o t i n t e r n a t i o n a l . c o m
Precision Onco-Imaging
using state-of-the art
PET/CT
FIRST IN
SOUTH
INDIA
Targeted Radionuclide Therapy:
MIOT opens the door to better and safer treatment beyond imaging:
In addition to the wide range of diagnostic services (using PET/CT and SPECT) the Department of Nuclear Medicine at MIOT is
equipped with the state-of-the-art radionuclide therapy ward for providing ‘Targeted Radionuclide therapy’ for certain cancers.
Targeted Radionuclide Therapy is rapidly evolving into an alternative mode of treatment in oncology with better tumor
targeting and lesser treatment related toxicity than conventional chemotherapy / external beam radiotherapy. Several
randomized and ongoing clinical trials in cancer patients have shown its potential to improve quality of life and also increase
the overall and disease specific survival.
Following are the radionuclide therapies available in MIOT.
Radio-iodine therapy for localized and metastatic thyroid cancer.
Radio-iodinated MIBG therapy for pheochromocytomas/paragangliomas.
‘Peptide Receptor Radionuclide Therapy’ (PRRT) for neuroendocrine tumors.
Radio-embolization therapy for primary and metastatic liver cancers.
For further clarification or for an appointment, please call at 044 4200 2288 (extn 4452) or email us at
nuclearmedicine@miothospitals.com
Diagnosis to rehabilitation - under one roof
We are one of the few centres in India offering complete
care from diagnosis to treatment and rehabilitation in a single
facility. We fight alongside our patients with the world’s
latest treatments and a wealth of experience and expertise.
World-class imaging & laboratory facilities -
for accurate diagnosis
Our imaging and diagnostic facilities, which include a
state-of-the-art laboratory that is ranked 8th in the world and
advanced imaging modalities, deliver speedy and accurate
reports.
Full time dedicated team of Oncologists,
customised treatment plans
Our team of Oncologists works with other specialists to
devise a customised treatment plan that is comfortable for
every patient. The goal is to ensure that patients complete
their course of treatment as planned. This is essential for their
effective recovery and return to normal life.
New-wave treatment with focus on patient
comfort
We offer the latest chemotherapeutic drugs and are hence
able to anticipate and offset side effects with pre-medications
which make treatment easier. In surgery, we work with other
specialists, including reconstructive surgeons, to preserve as
much of the patient’s organ as we can while removing the
cancerous tissue completely.
Most Advanced Radiotherapy
MIOT International was among the first hospitals in India to
offer the world’s most advanced Radiotherapy - with True-
Beam STx. Safer, faster and more accurate, TrueBeam STx
delivers image-guided, patient friendly treatment in mere
minutes.
Team Effort
Patient’s health is of paramount importance to us and they
deserve the most advanced in cancer care technology. With
our well-trained teams, the latest in cancer detection systems
and an ambience of compassion and care, MIOT Institute Of
Cancer Cure is a best ally to patients against cancer.
We are open six days a week. Please call for an appointment
at 044 4200 2288 (extn 5081) or email us at
onco@miothospitals.com to bring your patient back to
normal life.
How will PET/CT scan help in a
patient’s treatment?
Improved Diagnosis:
See MORE, See BETTER, See EARLIER:
The significantly
improved precision
(higher imaging
/ diagnostic accuracy)
of co-registration of
anatomy and function
(down to the
molecullar level)
by the PET/CT results in improved reader (nuclear
physician) confidence
in earlier detection of disease
precise localization and interpretation
(characterization) of the hyper metabolic disease areas
marked reduction in inconclusive scan findings.
Better Evaluation and devising treatment
protocol:
The PET/CT scan results not only help to have a major
impact on physicians’ diagnosis of cancer but also helps
the physician to predict the likely outcome of
various therapeutic alternatives during primary
staging / re-staging of cancer
planning and individualizing treatment protocols and
methods by efficiently monitoring the response of the
disease to treatment .
Impacting disease management & lives:
Lesser time & better patient compliance
Both functional and detailed anatomical imaging
done in a single setting.
Avoiding un-necessary surgeries and invasive
procedures.
Reducing treatment related side effects.
Reducing overall treatment costs.
Besides revolutionizing cancer diagnosis and
treatment protocols, the PET/CT is a powerful
tool for diagnostic assessment of modern day
diseases such as neuro degenerative disorders
(alzeihmer’s, parkinsons disease etc..) and
coronary artery disease.
Sensitivity.
Accuracy.
Confidence.
The GE IQ PET/CT at MIOT International (1st of its kind in South India) offers
Superior Image Quality and Intelligent Quantitation enabling the Physician to
discover and diagnose cancer confidently. Now, we can detect even minute
abnormalities and offer accurate diagnoses and monitoring to our patients.
TM
GE Healthcare’s Discovery
IQ PET/CT , powered by
Q.Clear reconstruction technology,
Superior Imaging Intelligent Quantitation
Greater Scalability Better Patient Management
Largest axial field-of-view for full-organ scans
and greater throughput
Highest NEMA Sensitivity for outstanding
small lesion detectability at low dose
Highest clinical NECR for 18F-based tracers
optimized for oncology practices
Q.Clear reconstruction technology for up to 2x
improvement in image quality (SNR)
Q.Suite to deliver consistent SUV measurements
with up to 2x improvement in quantitation
accuracy (SUVmean)
Dual Acquisition Channels which ensure high
quantitation accuracy for both low and
high-count rate isotopes
Fully-scalable detector
Field-upgradable PET Axial Field-of-View
Mobile-ready platform
46% additional lesion detection with FDB
PET/CT
36% reduced unwanted procedures
13% Improved Diagnostic Accuracy
20% Improved Staging Accuracy
What is a PET/CT?
PET/CT is the work horse of modern onco
imaging which can detect disease that is not
identified on conventional CT scans alone.
PET/CT scan consists of 2 components – the
diagnostic CT (computed tomography) scan
(anatomical) and the PET (positron emission
tomography) scan (functional) – both in the same
sitting.
Case study:
Mr. Raman, a 60 year old retired professor approached
a city hospital after symptoms of persistent & intense cough
with severe shortness of breath. There he underwent a CECT
(Fig 1 - contrast enhanced computed tomography) which
pointed out that he had a 1.5 cm spiculated mass in the upper
lobe of his left lung.
Since there was a spiculated mass (it is a lump of tissue with
spikes or points on the surface and it is suggestive of cancer) his
doctor directly suggested lobectomy (lung cancer surgery in
which one lobe of the lung is removed). Jolted by the suggestion
of lung removal surgery, Mr. Raman’s family sought a second
opinion from MIOT, as suggested by his son’s colleagues.
Mr. Raman’s case was put to the MIOT Tumor Board and there
it was decided that he undergoes a PET/CT scan first, in order
to understand the metabolic information of the tumor as the
previous CT scan captured only the anatomic information.
The PET/CT scan showed focal FDG uptake in the spiculated
soft tissue mass in the left lung upper lobe, subcm (below 1 cm)
left hilar node (Fig 2) and also a small lytic skeletal metastasis in
the left iliac bone (Fig 4), which was not apparent on
CECT (Fig 3).
FDG (fluoro deoxy glucose) is a commonly used radiotracer for
PET/CT imaging. Before the PET/CT scan, a small amount of FDG
is injected into the patient. Because cancer grows at a faster rate
than healthy tissue, cancer cells absorb more of the FDG.
As a result, Mr. Raman was upstaged from local disease to
stage IV – there by changing management from surgery to
palliative chemotherapy.
This case demonstrates the significance of staging PET/CT on
disease management in highly malignant tumours like
carcinoma lung. International literature confirms the huge
importance of PET CT in cancer diagnosis as it changes the
treatment management in 30% of patients.
(Fig 1 - CECT) (Fig 2 - PET/CT)
(Fig 3 - CECT) (Fig 4 - PET/CT)
How will PET/CT scan help in a
patient’s treatment?
Improved Diagnosis:
See MORE, See BETTER, See EARLIER:
The significantly
improved precision
(higher imaging
/ diagnostic accuracy)
of co-registration of
anatomy and function
(down to the
molecullar level)
by the PET/CT results in improved reader (nuclear
physician) confidence
in earlier detection of disease
precise localization and interpretation
(characterization) of the hyper metabolic disease areas
marked reduction in inconclusive scan findings.
Better Evaluation and devising treatment
protocol:
The PET/CT scan results not only help to have a major
impact on physicians’ diagnosis of cancer but also helps
the physician to predict the likely outcome of
various therapeutic alternatives during primary
staging / re-staging of cancer
planning and individualizing treatment protocols and
methods by efficiently monitoring the response of the
disease to treatment .
Impacting disease management & lives:
Lesser time & better patient compliance
Both functional and detailed anatomical imaging
done in a single setting.
Avoiding un-necessary surgeries and invasive
procedures.
Reducing treatment related side effects.
Reducing overall treatment costs.
Besides revolutionizing cancer diagnosis and
treatment protocols, the PET/CT is a powerful
tool for diagnostic assessment of modern day
diseases such as neuro degenerative disorders
(alzeihmer’s, parkinsons disease etc..) and
coronary artery disease.
Sensitivity.
Accuracy.
Confidence.
The GE IQ PET/CT at MIOT International (1st of its kind in South India) offers
Superior Image Quality and Intelligent Quantitation enabling the Physician to
discover and diagnose cancer confidently. Now, we can detect even minute
abnormalities and offer accurate diagnoses and monitoring to our patients.
TM
GE Healthcare’s Discovery
IQ PET/CT , powered by
Q.Clear reconstruction technology,
Superior Imaging Intelligent Quantitation
Greater Scalability Better Patient Management
Largest axial field-of-view for full-organ scans
and greater throughput
Highest NEMA Sensitivity for outstanding
small lesion detectability at low dose
Highest clinical NECR for 18F-based tracers
optimized for oncology practices
Q.Clear reconstruction technology for up to 2x
improvement in image quality (SNR)
Q.Suite to deliver consistent SUV measurements
with up to 2x improvement in quantitation
accuracy (SUVmean)
Dual Acquisition Channels which ensure high
quantitation accuracy for both low and
high-count rate isotopes
Fully-scalable detector
Field-upgradable PET Axial Field-of-View
Mobile-ready platform
46% additional lesion detection with FDB
PET/CT
36% reduced unwanted procedures
13% Improved Diagnostic Accuracy
20% Improved Staging Accuracy
What is a PET/CT?
PET/CT is the work horse of modern onco
imaging which can detect disease that is not
identified on conventional CT scans alone.
PET/CT scan consists of 2 components – the
diagnostic CT (computed tomography) scan
(anatomical) and the PET (positron emission
tomography) scan (functional) – both in the same
sitting.
Case study:
Mr. Raman, a 60 year old retired professor approached
a city hospital after symptoms of persistent & intense cough
with severe shortness of breath. There he underwent a CECT
(Fig 1 - contrast enhanced computed tomography) which
pointed out that he had a 1.5 cm spiculated mass in the upper
lobe of his left lung.
Since there was a spiculated mass (it is a lump of tissue with
spikes or points on the surface and it is suggestive of cancer) his
doctor directly suggested lobectomy (lung cancer surgery in
which one lobe of the lung is removed). Jolted by the suggestion
of lung removal surgery, Mr. Raman’s family sought a second
opinion from MIOT, as suggested by his son’s colleagues.
Mr. Raman’s case was put to the MIOT Tumor Board and there
it was decided that he undergoes a PET/CT scan first, in order
to understand the metabolic information of the tumor as the
previous CT scan captured only the anatomic information.
The PET/CT scan showed focal FDG uptake in the spiculated
soft tissue mass in the left lung upper lobe, subcm (below 1 cm)
left hilar node (Fig 2) and also a small lytic skeletal metastasis in
the left iliac bone (Fig 4), which was not apparent on
CECT (Fig 3).
FDG (fluoro deoxy glucose) is a commonly used radiotracer for
PET/CT imaging. Before the PET/CT scan, a small amount of FDG
is injected into the patient. Because cancer grows at a faster rate
than healthy tissue, cancer cells absorb more of the FDG.
As a result, Mr. Raman was upstaged from local disease to
stage IV – there by changing management from surgery to
palliative chemotherapy.
This case demonstrates the significance of staging PET/CT on
disease management in highly malignant tumours like
carcinoma lung. International literature confirms the huge
importance of PET CT in cancer diagnosis as it changes the
treatment management in 30% of patients.
(Fig 1 - CECT) (Fig 2 - PET/CT)
(Fig 3 - CECT) (Fig 4 - PET/CT)
MIOT Hospitals : 4/112, Mount Poonamallee Road, Manapakkam Chennai - 600089, India
Tel: +91 44 4200 2288, Fax: +91 44 2249 1313 Email: chief@miothospitals.com www.miotinternational.com
w w w . m i o t i n t e r n a t i o n a l . c o m
Precision Onco-Imaging
using state-of-the art
PET/CT
FIRST IN
SOUTH
INDIA
Targeted Radionuclide Therapy:
MIOT opens the door to better and safer treatment beyond imaging:
In addition to the wide range of diagnostic services (using PET/CT and SPECT) the Department of Nuclear Medicine at MIOT is
equipped with the state-of-the-art radionuclide therapy ward for providing ‘Targeted Radionuclide therapy’ for certain cancers.
Targeted Radionuclide Therapy is rapidly evolving into an alternative mode of treatment in oncology with better tumor
targeting and lesser treatment related toxicity than conventional chemotherapy / external beam radiotherapy. Several
randomized and ongoing clinical trials in cancer patients have shown its potential to improve quality of life and also increase
the overall and disease specific survival.
Following are the radionuclide therapies available in MIOT.
Radio-iodine therapy for localized and metastatic thyroid cancer.
Radio-iodinated MIBG therapy for pheochromocytomas/paragangliomas.
‘Peptide Receptor Radionuclide Therapy’ (PRRT) for neuroendocrine tumors.
Radio-embolization therapy for primary and metastatic liver cancers.
For further clarification or for an appointment, please call at 044 4200 2288 (extn 4452) or email us at
nuclearmedicine@miothospitals.com
Diagnosis to rehabilitation - under one roof
We are one of the few centres in India offering complete
care from diagnosis to treatment and rehabilitation in a single
facility. We fight alongside our patients with the world’s
latest treatments and a wealth of experience and expertise.
World-class imaging & laboratory facilities -
for accurate diagnosis
Our imaging and diagnostic facilities, which include a
state-of-the-art laboratory that is ranked 8th in the world and
advanced imaging modalities, deliver speedy and accurate
reports.
Full time dedicated team of Oncologists,
customised treatment plans
Our team of Oncologists works with other specialists to
devise a customised treatment plan that is comfortable for
every patient. The goal is to ensure that patients complete
their course of treatment as planned. This is essential for their
effective recovery and return to normal life.
New-wave treatment with focus on patient
comfort
We offer the latest chemotherapeutic drugs and are hence
able to anticipate and offset side effects with pre-medications
which make treatment easier. In surgery, we work with other
specialists, including reconstructive surgeons, to preserve as
much of the patient’s organ as we can while removing the
cancerous tissue completely.
Most Advanced Radiotherapy
MIOT International was among the first hospitals in India to
offer the world’s most advanced Radiotherapy - with True-
Beam STx. Safer, faster and more accurate, TrueBeam STx
delivers image-guided, patient friendly treatment in mere
minutes.
Team Effort
Patient’s health is of paramount importance to us and they
deserve the most advanced in cancer care technology. With
our well-trained teams, the latest in cancer detection systems
and an ambience of compassion and care, MIOT Institute Of
Cancer Cure is a best ally to patients against cancer.
We are open six days a week. Please call for an appointment
at 044 4200 2288 (extn 5081) or email us at
onco@miothospitals.com to bring your patient back to
normal life.

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MIOT Hospitals Precision Onco-Imaging and Targeted Radionuclide Therapy

  • 1. MIOT Hospitals : 4/112, Mount Poonamallee Road, Manapakkam Chennai - 600089, India Tel: +91 44 4200 2288, Fax: +91 44 2249 1313 Email: chief@miothospitals.com www.miotinternational.com w w w . m i o t i n t e r n a t i o n a l . c o m Precision Onco-Imaging using state-of-the art PET/CT FIRST IN SOUTH INDIA Targeted Radionuclide Therapy: MIOT opens the door to better and safer treatment beyond imaging: In addition to the wide range of diagnostic services (using PET/CT and SPECT) the Department of Nuclear Medicine at MIOT is equipped with the state-of-the-art radionuclide therapy ward for providing ‘Targeted Radionuclide therapy’ for certain cancers. Targeted Radionuclide Therapy is rapidly evolving into an alternative mode of treatment in oncology with better tumor targeting and lesser treatment related toxicity than conventional chemotherapy / external beam radiotherapy. Several randomized and ongoing clinical trials in cancer patients have shown its potential to improve quality of life and also increase the overall and disease specific survival. Following are the radionuclide therapies available in MIOT. Radio-iodine therapy for localized and metastatic thyroid cancer. Radio-iodinated MIBG therapy for pheochromocytomas/paragangliomas. ‘Peptide Receptor Radionuclide Therapy’ (PRRT) for neuroendocrine tumors. Radio-embolization therapy for primary and metastatic liver cancers. For further clarification or for an appointment, please call at 044 4200 2288 (extn 4452) or email us at nuclearmedicine@miothospitals.com Diagnosis to rehabilitation - under one roof We are one of the few centres in India offering complete care from diagnosis to treatment and rehabilitation in a single facility. We fight alongside our patients with the world’s latest treatments and a wealth of experience and expertise. World-class imaging & laboratory facilities - for accurate diagnosis Our imaging and diagnostic facilities, which include a state-of-the-art laboratory that is ranked 8th in the world and advanced imaging modalities, deliver speedy and accurate reports. Full time dedicated team of Oncologists, customised treatment plans Our team of Oncologists works with other specialists to devise a customised treatment plan that is comfortable for every patient. The goal is to ensure that patients complete their course of treatment as planned. This is essential for their effective recovery and return to normal life. New-wave treatment with focus on patient comfort We offer the latest chemotherapeutic drugs and are hence able to anticipate and offset side effects with pre-medications which make treatment easier. In surgery, we work with other specialists, including reconstructive surgeons, to preserve as much of the patient’s organ as we can while removing the cancerous tissue completely. Most Advanced Radiotherapy MIOT International was among the first hospitals in India to offer the world’s most advanced Radiotherapy - with True- Beam STx. Safer, faster and more accurate, TrueBeam STx delivers image-guided, patient friendly treatment in mere minutes. Team Effort Patient’s health is of paramount importance to us and they deserve the most advanced in cancer care technology. With our well-trained teams, the latest in cancer detection systems and an ambience of compassion and care, MIOT Institute Of Cancer Cure is a best ally to patients against cancer. We are open six days a week. Please call for an appointment at 044 4200 2288 (extn 5081) or email us at onco@miothospitals.com to bring your patient back to normal life.
  • 2. How will PET/CT scan help in a patient’s treatment? Improved Diagnosis: See MORE, See BETTER, See EARLIER: The significantly improved precision (higher imaging / diagnostic accuracy) of co-registration of anatomy and function (down to the molecullar level) by the PET/CT results in improved reader (nuclear physician) confidence in earlier detection of disease precise localization and interpretation (characterization) of the hyper metabolic disease areas marked reduction in inconclusive scan findings. Better Evaluation and devising treatment protocol: The PET/CT scan results not only help to have a major impact on physicians’ diagnosis of cancer but also helps the physician to predict the likely outcome of various therapeutic alternatives during primary staging / re-staging of cancer planning and individualizing treatment protocols and methods by efficiently monitoring the response of the disease to treatment . Impacting disease management & lives: Lesser time & better patient compliance Both functional and detailed anatomical imaging done in a single setting. Avoiding un-necessary surgeries and invasive procedures. Reducing treatment related side effects. Reducing overall treatment costs. Besides revolutionizing cancer diagnosis and treatment protocols, the PET/CT is a powerful tool for diagnostic assessment of modern day diseases such as neuro degenerative disorders (alzeihmer’s, parkinsons disease etc..) and coronary artery disease. Sensitivity. Accuracy. Confidence. The GE IQ PET/CT at MIOT International (1st of its kind in South India) offers Superior Image Quality and Intelligent Quantitation enabling the Physician to discover and diagnose cancer confidently. Now, we can detect even minute abnormalities and offer accurate diagnoses and monitoring to our patients. TM GE Healthcare’s Discovery IQ PET/CT , powered by Q.Clear reconstruction technology, Superior Imaging Intelligent Quantitation Greater Scalability Better Patient Management Largest axial field-of-view for full-organ scans and greater throughput Highest NEMA Sensitivity for outstanding small lesion detectability at low dose Highest clinical NECR for 18F-based tracers optimized for oncology practices Q.Clear reconstruction technology for up to 2x improvement in image quality (SNR) Q.Suite to deliver consistent SUV measurements with up to 2x improvement in quantitation accuracy (SUVmean) Dual Acquisition Channels which ensure high quantitation accuracy for both low and high-count rate isotopes Fully-scalable detector Field-upgradable PET Axial Field-of-View Mobile-ready platform 46% additional lesion detection with FDB PET/CT 36% reduced unwanted procedures 13% Improved Diagnostic Accuracy 20% Improved Staging Accuracy What is a PET/CT? PET/CT is the work horse of modern onco imaging which can detect disease that is not identified on conventional CT scans alone. PET/CT scan consists of 2 components – the diagnostic CT (computed tomography) scan (anatomical) and the PET (positron emission tomography) scan (functional) – both in the same sitting. Case study: Mr. Raman, a 60 year old retired professor approached a city hospital after symptoms of persistent & intense cough with severe shortness of breath. There he underwent a CECT (Fig 1 - contrast enhanced computed tomography) which pointed out that he had a 1.5 cm spiculated mass in the upper lobe of his left lung. Since there was a spiculated mass (it is a lump of tissue with spikes or points on the surface and it is suggestive of cancer) his doctor directly suggested lobectomy (lung cancer surgery in which one lobe of the lung is removed). Jolted by the suggestion of lung removal surgery, Mr. Raman’s family sought a second opinion from MIOT, as suggested by his son’s colleagues. Mr. Raman’s case was put to the MIOT Tumor Board and there it was decided that he undergoes a PET/CT scan first, in order to understand the metabolic information of the tumor as the previous CT scan captured only the anatomic information. The PET/CT scan showed focal FDG uptake in the spiculated soft tissue mass in the left lung upper lobe, subcm (below 1 cm) left hilar node (Fig 2) and also a small lytic skeletal metastasis in the left iliac bone (Fig 4), which was not apparent on CECT (Fig 3). FDG (fluoro deoxy glucose) is a commonly used radiotracer for PET/CT imaging. Before the PET/CT scan, a small amount of FDG is injected into the patient. Because cancer grows at a faster rate than healthy tissue, cancer cells absorb more of the FDG. As a result, Mr. Raman was upstaged from local disease to stage IV – there by changing management from surgery to palliative chemotherapy. This case demonstrates the significance of staging PET/CT on disease management in highly malignant tumours like carcinoma lung. International literature confirms the huge importance of PET CT in cancer diagnosis as it changes the treatment management in 30% of patients. (Fig 1 - CECT) (Fig 2 - PET/CT) (Fig 3 - CECT) (Fig 4 - PET/CT)
  • 3. How will PET/CT scan help in a patient’s treatment? Improved Diagnosis: See MORE, See BETTER, See EARLIER: The significantly improved precision (higher imaging / diagnostic accuracy) of co-registration of anatomy and function (down to the molecullar level) by the PET/CT results in improved reader (nuclear physician) confidence in earlier detection of disease precise localization and interpretation (characterization) of the hyper metabolic disease areas marked reduction in inconclusive scan findings. Better Evaluation and devising treatment protocol: The PET/CT scan results not only help to have a major impact on physicians’ diagnosis of cancer but also helps the physician to predict the likely outcome of various therapeutic alternatives during primary staging / re-staging of cancer planning and individualizing treatment protocols and methods by efficiently monitoring the response of the disease to treatment . Impacting disease management & lives: Lesser time & better patient compliance Both functional and detailed anatomical imaging done in a single setting. Avoiding un-necessary surgeries and invasive procedures. Reducing treatment related side effects. Reducing overall treatment costs. Besides revolutionizing cancer diagnosis and treatment protocols, the PET/CT is a powerful tool for diagnostic assessment of modern day diseases such as neuro degenerative disorders (alzeihmer’s, parkinsons disease etc..) and coronary artery disease. Sensitivity. Accuracy. Confidence. The GE IQ PET/CT at MIOT International (1st of its kind in South India) offers Superior Image Quality and Intelligent Quantitation enabling the Physician to discover and diagnose cancer confidently. Now, we can detect even minute abnormalities and offer accurate diagnoses and monitoring to our patients. TM GE Healthcare’s Discovery IQ PET/CT , powered by Q.Clear reconstruction technology, Superior Imaging Intelligent Quantitation Greater Scalability Better Patient Management Largest axial field-of-view for full-organ scans and greater throughput Highest NEMA Sensitivity for outstanding small lesion detectability at low dose Highest clinical NECR for 18F-based tracers optimized for oncology practices Q.Clear reconstruction technology for up to 2x improvement in image quality (SNR) Q.Suite to deliver consistent SUV measurements with up to 2x improvement in quantitation accuracy (SUVmean) Dual Acquisition Channels which ensure high quantitation accuracy for both low and high-count rate isotopes Fully-scalable detector Field-upgradable PET Axial Field-of-View Mobile-ready platform 46% additional lesion detection with FDB PET/CT 36% reduced unwanted procedures 13% Improved Diagnostic Accuracy 20% Improved Staging Accuracy What is a PET/CT? PET/CT is the work horse of modern onco imaging which can detect disease that is not identified on conventional CT scans alone. PET/CT scan consists of 2 components – the diagnostic CT (computed tomography) scan (anatomical) and the PET (positron emission tomography) scan (functional) – both in the same sitting. Case study: Mr. Raman, a 60 year old retired professor approached a city hospital after symptoms of persistent & intense cough with severe shortness of breath. There he underwent a CECT (Fig 1 - contrast enhanced computed tomography) which pointed out that he had a 1.5 cm spiculated mass in the upper lobe of his left lung. Since there was a spiculated mass (it is a lump of tissue with spikes or points on the surface and it is suggestive of cancer) his doctor directly suggested lobectomy (lung cancer surgery in which one lobe of the lung is removed). Jolted by the suggestion of lung removal surgery, Mr. Raman’s family sought a second opinion from MIOT, as suggested by his son’s colleagues. Mr. Raman’s case was put to the MIOT Tumor Board and there it was decided that he undergoes a PET/CT scan first, in order to understand the metabolic information of the tumor as the previous CT scan captured only the anatomic information. The PET/CT scan showed focal FDG uptake in the spiculated soft tissue mass in the left lung upper lobe, subcm (below 1 cm) left hilar node (Fig 2) and also a small lytic skeletal metastasis in the left iliac bone (Fig 4), which was not apparent on CECT (Fig 3). FDG (fluoro deoxy glucose) is a commonly used radiotracer for PET/CT imaging. Before the PET/CT scan, a small amount of FDG is injected into the patient. Because cancer grows at a faster rate than healthy tissue, cancer cells absorb more of the FDG. As a result, Mr. Raman was upstaged from local disease to stage IV – there by changing management from surgery to palliative chemotherapy. This case demonstrates the significance of staging PET/CT on disease management in highly malignant tumours like carcinoma lung. International literature confirms the huge importance of PET CT in cancer diagnosis as it changes the treatment management in 30% of patients. (Fig 1 - CECT) (Fig 2 - PET/CT) (Fig 3 - CECT) (Fig 4 - PET/CT)
  • 4. MIOT Hospitals : 4/112, Mount Poonamallee Road, Manapakkam Chennai - 600089, India Tel: +91 44 4200 2288, Fax: +91 44 2249 1313 Email: chief@miothospitals.com www.miotinternational.com w w w . m i o t i n t e r n a t i o n a l . c o m Precision Onco-Imaging using state-of-the art PET/CT FIRST IN SOUTH INDIA Targeted Radionuclide Therapy: MIOT opens the door to better and safer treatment beyond imaging: In addition to the wide range of diagnostic services (using PET/CT and SPECT) the Department of Nuclear Medicine at MIOT is equipped with the state-of-the-art radionuclide therapy ward for providing ‘Targeted Radionuclide therapy’ for certain cancers. Targeted Radionuclide Therapy is rapidly evolving into an alternative mode of treatment in oncology with better tumor targeting and lesser treatment related toxicity than conventional chemotherapy / external beam radiotherapy. Several randomized and ongoing clinical trials in cancer patients have shown its potential to improve quality of life and also increase the overall and disease specific survival. Following are the radionuclide therapies available in MIOT. Radio-iodine therapy for localized and metastatic thyroid cancer. Radio-iodinated MIBG therapy for pheochromocytomas/paragangliomas. ‘Peptide Receptor Radionuclide Therapy’ (PRRT) for neuroendocrine tumors. Radio-embolization therapy for primary and metastatic liver cancers. For further clarification or for an appointment, please call at 044 4200 2288 (extn 4452) or email us at nuclearmedicine@miothospitals.com Diagnosis to rehabilitation - under one roof We are one of the few centres in India offering complete care from diagnosis to treatment and rehabilitation in a single facility. We fight alongside our patients with the world’s latest treatments and a wealth of experience and expertise. World-class imaging & laboratory facilities - for accurate diagnosis Our imaging and diagnostic facilities, which include a state-of-the-art laboratory that is ranked 8th in the world and advanced imaging modalities, deliver speedy and accurate reports. Full time dedicated team of Oncologists, customised treatment plans Our team of Oncologists works with other specialists to devise a customised treatment plan that is comfortable for every patient. The goal is to ensure that patients complete their course of treatment as planned. This is essential for their effective recovery and return to normal life. New-wave treatment with focus on patient comfort We offer the latest chemotherapeutic drugs and are hence able to anticipate and offset side effects with pre-medications which make treatment easier. In surgery, we work with other specialists, including reconstructive surgeons, to preserve as much of the patient’s organ as we can while removing the cancerous tissue completely. Most Advanced Radiotherapy MIOT International was among the first hospitals in India to offer the world’s most advanced Radiotherapy - with True- Beam STx. Safer, faster and more accurate, TrueBeam STx delivers image-guided, patient friendly treatment in mere minutes. Team Effort Patient’s health is of paramount importance to us and they deserve the most advanced in cancer care technology. With our well-trained teams, the latest in cancer detection systems and an ambience of compassion and care, MIOT Institute Of Cancer Cure is a best ally to patients against cancer. We are open six days a week. Please call for an appointment at 044 4200 2288 (extn 5081) or email us at onco@miothospitals.com to bring your patient back to normal life.