The document explores how ethical issues significantly influence scientific progress, illustrated through historical cases like Dr. Robert Cornish's attempts to revitalize deceased animals and seek human testing, which were thwarted by legal and ethical concerns. It also discusses the ongoing debates surrounding human stem cell research, emphasizing the potential medical advancements against ethical dilemmas related to embryo use. Additionally, the impact of ethical considerations on the production and use of genetically modified organisms (GMOs) is highlighted.

1. Deepanshu Sharma
B.tech+M.tech (B&B)
Converging Technology

5. How
ethical issues
influence
progress in
Science?

6. To understand this, we will see
few cases from history.
If those technology/knowledge
were not blocked by ‘Ethical
Issues’…
then they might had changed
the fate of human civilization.

9. His method to reanimate living system
was successful and he managed to revive
two dogs (Lazarus IV and V) clinically put
to death on May 22, 1934 and in 1935.
Dr. Robert E. Cornish (1903 –1963) had
graduated from the University of California,
with honors and received a doctorate by
the time he was just 22.

10. Cornish wished to expand his clinical trials
to include human testing.
So he contacted judicial system to seek
permission to test his experiment on death-
row prisoners.
Thomas McMonigle offered his body for
possible reanimation. But California law
enforcement refused Cornish’s petition,
however, due to concerns a reanimated
murderer would have to be freed under the
“double jeopardy” clause.

11. After denial of the petition, McMonigle was
executed in San Quentin's gas chamber on
20 February 1948.
And Dr. Cornish had never tested his
experiment again.
He spent his last days working in a
toothpaste company and died at very
early age of 60.

13. Since the first report of the isolation of human stem
cells from surplus IVF embryos in 1998, their derivation
and use has been hotly debated by governments, press
and society in many parts of the world. Driving the
debate has been the shortage of donor organs and
tissues for regenerative medicine; diseases such as
diabetes, Parkinson and rheumatoid arthritis caused
by the loss or loss-of-function of specific cell types,
could be cured if healthy cells replace defective cells.
However, ethical considerations question the
instrumental use of embryos for the isolation of stem
cells, even if those embryos are surplus to
requirements for assisted reproduction and destined
for destruction.

14. Use and production
of GMO is also
affected by the
bars of ethical
issues.

17. Thank you 