This document provides an overview of environmental medicine as it relates to drowning and electrical injuries. It defines drowning and discusses epidemiology, risk factors, pathophysiology, symptoms, diagnosis, treatment and prevention of drowning. Globally, drowning causes 380,000 deaths per year. Risk factors include lack of supervision for children and alcohol use for adults. Pathophysiology involves laryngeal spasm and hypoxia/asphyxiation. Treatment focuses on rescue breathing, warming, and monitoring for complications. Prevention strategies target child supervision and barriers around pools. The document also covers definitions, pathophysiology involving current strength and duration, symptoms, diagnosis, and treatment of electrical injuries as well as prevention through insulation and circuit breakers
Spinal cord injuries can cause partial or complete loss of motor and sensory function below the site of injury. There are several types of spinal cord injuries including complete and incomplete injuries. Risk factors include men, young adults, seniors, and those active in sports. Causes include trauma, bullet wounds, and falls. Symptoms depend on the injury level but may include paralysis, numbness, loss of bowel/bladder control. Diagnostic tests include imaging like CT, MRI to determine injury level and severity. Complications can include autonomic dysreflexia, pressure sores, loss of sexual function. Treatment involves stabilizing the spine, managing complications, and long-term rehabilitation.
Most hip fractures occur in people over 65 from falls and weakening of the bone from conditions like osteoporosis. A hip fracture is diagnosed using x-rays, MRI, CT scan or bone scan and usually requires surgery within 24 hours. Recovery involves physical therapy and lifestyle changes to strengthen bones and prevent future fractures like exercising, good nutrition, limiting alcohol and not smoking.
This document discusses cold injuries that can occur from exposure to extreme cold, including hypothermia, frostbite, chilblains, dehydration, carbon monoxide poisoning, and snow blindness. It defines each injury, describes symptoms, treatment, prevention, and nursing considerations. The main cold injuries discussed are hypothermia, which lowers core body temperature, and frostbite, which is the freezing of body tissue that can lead to loss of fingers, toes, or other body parts if not promptly treated. Prevention is key and includes proper clothing, limiting time in extreme cold, staying dry and hydrated.
1. Acute renal failure (ARF) is an acute, potentially reversible condition where the kidneys fail to maintain homeostasis. Causes include prerenal factors like shock, congestive heart failure, or intrarenal injury from toxins. Symptoms range from nonspecific like fever to specific kidney issues like electrolyte imbalances. Treatment focuses on fluid management, electrolyte replacement, and potentially dialysis.
2. Chronic renal failure is a permanent loss of kidney function that progresses to end stage renal disease. It is usually caused by congenital anomalies or acquired glomerular diseases. Symptoms emerge late and include fatigue, nausea, and cardiac/bone issues. Treatment manages complications and slows progression with a low protein
This document provides an overview of leukemia, including its definition, types, causes, symptoms, diagnosis, treatment, and nursing management. It discusses the main types of leukemia - acute lymphocytic leukemia, acute myeloid leukemia, chronic lymphocytic leukemia, and chronic myeloid leukemia. For each type, it covers clinical manifestations, diagnostic evaluation, medical management options like chemotherapy and stem cell transplantation, and associated nursing care. The document also reviews the TNM staging system and mentions a research study on imatinib therapy for chronic myeloid leukemia.
Septic arthritis is a joint infection caused by bacteria or other microbes entering the joint space. It leads to inflammation of the synovial membrane and purulent effusion. Common symptoms include pain, swelling, warmth and limited movement of the infected joint. Diagnosis involves synovial fluid analysis showing purulence and leukocytosis, along with supportive blood tests. Treatment is with antibiotics and surgical drainage may be needed. Complications can include bone and cartilage destruction, joint deformity, and secondary osteoarthritis.
Spinal cord injuries can cause partial or complete loss of motor and sensory function below the site of injury. There are several types of spinal cord injuries including complete and incomplete injuries. Risk factors include men, young adults, seniors, and those active in sports. Causes include trauma, bullet wounds, and falls. Symptoms depend on the injury level but may include paralysis, numbness, loss of bowel/bladder control. Diagnostic tests include imaging like CT, MRI to determine injury level and severity. Complications can include autonomic dysreflexia, pressure sores, loss of sexual function. Treatment involves stabilizing the spine, managing complications, and long-term rehabilitation.
Most hip fractures occur in people over 65 from falls and weakening of the bone from conditions like osteoporosis. A hip fracture is diagnosed using x-rays, MRI, CT scan or bone scan and usually requires surgery within 24 hours. Recovery involves physical therapy and lifestyle changes to strengthen bones and prevent future fractures like exercising, good nutrition, limiting alcohol and not smoking.
This document discusses cold injuries that can occur from exposure to extreme cold, including hypothermia, frostbite, chilblains, dehydration, carbon monoxide poisoning, and snow blindness. It defines each injury, describes symptoms, treatment, prevention, and nursing considerations. The main cold injuries discussed are hypothermia, which lowers core body temperature, and frostbite, which is the freezing of body tissue that can lead to loss of fingers, toes, or other body parts if not promptly treated. Prevention is key and includes proper clothing, limiting time in extreme cold, staying dry and hydrated.
1. Acute renal failure (ARF) is an acute, potentially reversible condition where the kidneys fail to maintain homeostasis. Causes include prerenal factors like shock, congestive heart failure, or intrarenal injury from toxins. Symptoms range from nonspecific like fever to specific kidney issues like electrolyte imbalances. Treatment focuses on fluid management, electrolyte replacement, and potentially dialysis.
2. Chronic renal failure is a permanent loss of kidney function that progresses to end stage renal disease. It is usually caused by congenital anomalies or acquired glomerular diseases. Symptoms emerge late and include fatigue, nausea, and cardiac/bone issues. Treatment manages complications and slows progression with a low protein
This document provides an overview of leukemia, including its definition, types, causes, symptoms, diagnosis, treatment, and nursing management. It discusses the main types of leukemia - acute lymphocytic leukemia, acute myeloid leukemia, chronic lymphocytic leukemia, and chronic myeloid leukemia. For each type, it covers clinical manifestations, diagnostic evaluation, medical management options like chemotherapy and stem cell transplantation, and associated nursing care. The document also reviews the TNM staging system and mentions a research study on imatinib therapy for chronic myeloid leukemia.
Septic arthritis is a joint infection caused by bacteria or other microbes entering the joint space. It leads to inflammation of the synovial membrane and purulent effusion. Common symptoms include pain, swelling, warmth and limited movement of the infected joint. Diagnosis involves synovial fluid analysis showing purulence and leukocytosis, along with supportive blood tests. Treatment is with antibiotics and surgical drainage may be needed. Complications can include bone and cartilage destruction, joint deformity, and secondary osteoarthritis.
This document provides an overview of burns, including definitions, classifications, pathophysiology, management, and complications. It defines burns as thermal injuries to the skin and tissues. Burns are classified based on depth and extent of damage. First, second, and third degree burns are described. Hospitalization is generally recommended for burns over 10% of total body surface area. The pathophysiology involves fluid shifts, cardiac, metabolic, immunologic, and renal effects. Burn management includes airway control, fluid resuscitation, wound care, infection prevention, pain relief, and nutrition. Complications can include shock, infection, renal failure, and scarring.
Crystal arthropathies gout & pseudogoutShinjan Patra
Gout is one of the most dangerous underrated acute emergency in rheumatological diseases. CPPD disease is an another entity which is very much under-diagnosed in respect t OA
Lymphedema is abnormal swelling caused by accumulation of lymph fluid due to defective lymphatic drainage. It can be primary (congenital) or secondary (acquired after surgery, radiation, infection, etc). Symptoms include swelling, heaviness, pain and skin changes. Management involves skin care, manual lymph drainage, compression bandages and garments, exercise and rarely surgery.
This document provides an overview of cerebrovascular disease and stroke. It defines stroke as an abrupt neurological deficit caused by a focal vascular issue. Strokes are classified as either ischemic, due to reduced blood flow, or hemorrhagic, caused by bleeding in the brain. The major risk factors for stroke include age, high blood pressure, heart disease, diabetes, and smoking. Diagnosis involves assessing clinical neurological signs and symptoms, and imaging tests like CT/MRI to determine if the stroke is ischemic or hemorrhagic and identify any underlying vascular abnormalities.
Stroke occurs when blood supply to part of the brain is disrupted, causing brain cells to die. It is usually caused by hypertension, heart disease, diabetes, or other conditions that damage blood vessels. Symptoms include weakness, confusion, trouble speaking, and visual/balance issues. Diagnosis involves physical exams, blood tests, and brain imaging tests. Treatment depends on the cause but may include clot-busting drugs, surgery to remove clots or repair burst vessels, and lifestyle changes to prevent future strokes. Nursing focuses on improving mobility, communication, skin integrity and family support.
This document provides guidelines on the principles of using plaster of Paris (POP) casts. It discusses the definition and properties of POP, including its chemical composition, setting time, drying time, and ideal characteristics. It covers classifications of POP casts based on application pattern and interposition of materials. It also lists indications, advantages, and disadvantages of POP casts. Detailed guidance is given on patient assessment, application technique, cast care, complications, and alternatives to POP.
External fixation is a method of stabilizing fractures using pins connected to an external frame. It is indicated for open fractures with soft tissue injury, long bone and pelvic fractures, and in multiple trauma patients. The basic components are pins inserted through bones, clamps connecting pins to rods or rings, and external rods or rings. Proper pin placement and construct are important for stability. Complications can include pin site infections, loosening, and breakage. Care includes daily inspection and cleaning of pins.
This document discusses spinal cord injuries, including causes such as trauma from accidents, most common vertebral levels injured, types of injuries, symptoms depending on injury level, complications, assessment, management including initial care, drug therapy, and long term care needs. Key points include trauma as the main cause, cervical vertebrae most commonly affected, complete versus incomplete injuries determined by degree of sensation and motor function loss below injury level, and management focusing on respiratory, cardiovascular, bladder, bowel and skin integrity issues.
Fibromyalgia is a syndrome characterized by chronic widespread pain, stiffness, and tenderness in the muscles and joints without signs of inflammation. It predominantly affects women between 35-55 years old and causes significant pain and fatigue that interferes with daily activities. While the exact cause is unknown, fibromyalgia is diagnosed by identifying tender points on the body and treatment focuses on managing symptoms through exercise, stress reduction, medications, and alternative therapies as there is no cure.
Stroke is defined as abrupt neurological deficit caused by reduced blood flow to the brain. It is the second leading cause of death worldwide, affecting over 70 million people annually. The main types are ischemic (88%) and hemorrhagic (12%) strokes. Major risk factors include age, hypertension, atrial fibrillation, diabetes, and smoking. Pathophysiology involves thrombosis, embolism, or bleeding that reduces blood flow and causes brain cell death from oxygen deprivation. Signs and symptoms include numbness, weakness, confusion, and headaches. Diagnosis involves imaging tests and lab work. Treatment focuses on revascularization, medication to reduce risk of future strokes, and rehabilitation.
Traction is used to overcome deforming forces on limbs affected by inflammation or fractures. There are two main types - skin traction and skeletal traction. Skin traction uses adhesive or non-adhesive strapping over a large area, while skeletal traction involves inserting pins or wires through bones. Traction must be counteracted to be effective, which can be done through fixed or sliding methods using appliances, body weight, or additional limbs. Common complications include injury, stiffness, infection, and pressure sores.
Mrs. B, a 65-year-old farmer, presented with sudden lower back pain and bilateral lower limb weakness. Imaging showed spondylodiscitis at D10-11. Blood cultures grew Pantoea agglomerans, an uncommon pathogen. She was treated with intravenous then oral ciprofloxacin for 6 weeks. Biopsy showed infective changes but was negative for tuberculosis. Her symptoms and inflammatory markers improved with antibiotics. Pantoea agglomerans is an opportunistic pathogen typically causing wound or urinary infections, and this represents a rare case of spondylodiscitis from this organism.
This document discusses inflammatory diseases of the bones and joints, focusing on osteomyelitis. It defines osteomyelitis as inflammation of all bone anatomical structures that is typically caused by common bacteria like Staphylococcus aureus. It describes the pathogenesis of hematogenous osteomyelitis, how it spreads through the bones, and can lead to complications like sepsis and fractures. Diagnosis involves x-rays and CT scans to identify features like periosteal reaction and bone destruction. Treatment involves antibiotics, surgery to debride infected areas, and managing complications.
This document provides an overview of bone tumors including:
- Definitions of bone tumors as abnormal bone cell growth that can be benign or malignant
- Classification systems that stage benign and malignant bone tumors based on factors like growth and spread
- Common clinical features of bone tumors like bone pain, lumps, fractures, and weight loss
- Diagnostic tests and treatment options for bone tumors including biopsy, imaging, chemotherapy, radiation, surgery and pain management
- Nursing considerations for patients with bone tumors which involve comprehensive assessment, developing a care plan and providing home care instructions.
This document provides an overview of bone tumors, including their definition, types, risk factors, clinical manifestations, diagnosis, and treatment. Bone tumors are abnormal bone growths that can be benign or malignant. Common types include osteosarcoma and chondrosarcoma. Risk factors include genetics, radiation exposure, and injuries. Symptoms may include pain, swelling, limited mobility. Diagnosis involves x-rays, bone scans, and MRIs. Treatment options are chemotherapy, radiation therapy, surgery such as amputation or reconstruction. Complications can include delayed healing, infections, and fractures. Prevention focuses on family history awareness, healthy lifestyle, and early diagnosis.
Concept Map of Syndrome of Inappropriate (ly high) Anti-Diuretic Hormone (SIADH)riddler2008
Optimized for the BlackBerry, iPhone, Windows mobile phone, Symbian smartphone screen as a reviewer on-the-go.
Write to riddler2008@msn.com for similar slideshows.
This document discusses bone tumors, including:
- Bone tumors can be benign or malignant and develop from uncontrolled cell division in bones. Common types include osteosarcoma, chondrosarcoma, and Ewing's sarcoma.
- Risk factors include genetic disorders, radiation exposure, and other cancers. Symptoms include bone pain, swelling, limited mobility, and pathological fractures.
- Diagnosis involves imaging like X-rays, CT, MRI and PET scans. Biopsies are also used to identify the tumor type and stage. Staging uses the TNM classification system to assess tumor size, spread to lymph nodes and distant organs.
Osteomyelitis is an infection of the bone that results in inflammation, necrosis, and new bone formation. It is classified as hematogenous, contiguous focus, or associated with vascular insufficiency. Staphylococcus aureus is the most common causative organism. Clinical manifestations include pain, swelling, and drainage from non-healing ulcers. Diagnosis involves imaging tests and biopsy. Treatment involves antibiotics, surgical debridement, and stabilization of the bone. Nursing care focuses on pain management, preventing complications like sepsis, and educating patients.
Drowning is a leading cause of accidental death in children worldwide. It occurs most commonly in males ages 1-5 years due to inadequate supervision near bodies of water. Drowning causes hypoxemia which quickly leads to respiratory and cardiac arrest. Survivors can have long-term pulmonary, neurological, cardiovascular and other injuries. Prompt rescue and resuscitation efforts on scene improve outcomes. In the hospital, management focuses on rewarming, correcting hypothermia, hypoxemia and other physiological derangements to prevent secondary neurological injury.
This document provides an overview of burns, including definitions, classifications, pathophysiology, management, and complications. It defines burns as thermal injuries to the skin and tissues. Burns are classified based on depth and extent of damage. First, second, and third degree burns are described. Hospitalization is generally recommended for burns over 10% of total body surface area. The pathophysiology involves fluid shifts, cardiac, metabolic, immunologic, and renal effects. Burn management includes airway control, fluid resuscitation, wound care, infection prevention, pain relief, and nutrition. Complications can include shock, infection, renal failure, and scarring.
Crystal arthropathies gout & pseudogoutShinjan Patra
Gout is one of the most dangerous underrated acute emergency in rheumatological diseases. CPPD disease is an another entity which is very much under-diagnosed in respect t OA
Lymphedema is abnormal swelling caused by accumulation of lymph fluid due to defective lymphatic drainage. It can be primary (congenital) or secondary (acquired after surgery, radiation, infection, etc). Symptoms include swelling, heaviness, pain and skin changes. Management involves skin care, manual lymph drainage, compression bandages and garments, exercise and rarely surgery.
This document provides an overview of cerebrovascular disease and stroke. It defines stroke as an abrupt neurological deficit caused by a focal vascular issue. Strokes are classified as either ischemic, due to reduced blood flow, or hemorrhagic, caused by bleeding in the brain. The major risk factors for stroke include age, high blood pressure, heart disease, diabetes, and smoking. Diagnosis involves assessing clinical neurological signs and symptoms, and imaging tests like CT/MRI to determine if the stroke is ischemic or hemorrhagic and identify any underlying vascular abnormalities.
Stroke occurs when blood supply to part of the brain is disrupted, causing brain cells to die. It is usually caused by hypertension, heart disease, diabetes, or other conditions that damage blood vessels. Symptoms include weakness, confusion, trouble speaking, and visual/balance issues. Diagnosis involves physical exams, blood tests, and brain imaging tests. Treatment depends on the cause but may include clot-busting drugs, surgery to remove clots or repair burst vessels, and lifestyle changes to prevent future strokes. Nursing focuses on improving mobility, communication, skin integrity and family support.
This document provides guidelines on the principles of using plaster of Paris (POP) casts. It discusses the definition and properties of POP, including its chemical composition, setting time, drying time, and ideal characteristics. It covers classifications of POP casts based on application pattern and interposition of materials. It also lists indications, advantages, and disadvantages of POP casts. Detailed guidance is given on patient assessment, application technique, cast care, complications, and alternatives to POP.
External fixation is a method of stabilizing fractures using pins connected to an external frame. It is indicated for open fractures with soft tissue injury, long bone and pelvic fractures, and in multiple trauma patients. The basic components are pins inserted through bones, clamps connecting pins to rods or rings, and external rods or rings. Proper pin placement and construct are important for stability. Complications can include pin site infections, loosening, and breakage. Care includes daily inspection and cleaning of pins.
This document discusses spinal cord injuries, including causes such as trauma from accidents, most common vertebral levels injured, types of injuries, symptoms depending on injury level, complications, assessment, management including initial care, drug therapy, and long term care needs. Key points include trauma as the main cause, cervical vertebrae most commonly affected, complete versus incomplete injuries determined by degree of sensation and motor function loss below injury level, and management focusing on respiratory, cardiovascular, bladder, bowel and skin integrity issues.
Fibromyalgia is a syndrome characterized by chronic widespread pain, stiffness, and tenderness in the muscles and joints without signs of inflammation. It predominantly affects women between 35-55 years old and causes significant pain and fatigue that interferes with daily activities. While the exact cause is unknown, fibromyalgia is diagnosed by identifying tender points on the body and treatment focuses on managing symptoms through exercise, stress reduction, medications, and alternative therapies as there is no cure.
Stroke is defined as abrupt neurological deficit caused by reduced blood flow to the brain. It is the second leading cause of death worldwide, affecting over 70 million people annually. The main types are ischemic (88%) and hemorrhagic (12%) strokes. Major risk factors include age, hypertension, atrial fibrillation, diabetes, and smoking. Pathophysiology involves thrombosis, embolism, or bleeding that reduces blood flow and causes brain cell death from oxygen deprivation. Signs and symptoms include numbness, weakness, confusion, and headaches. Diagnosis involves imaging tests and lab work. Treatment focuses on revascularization, medication to reduce risk of future strokes, and rehabilitation.
Traction is used to overcome deforming forces on limbs affected by inflammation or fractures. There are two main types - skin traction and skeletal traction. Skin traction uses adhesive or non-adhesive strapping over a large area, while skeletal traction involves inserting pins or wires through bones. Traction must be counteracted to be effective, which can be done through fixed or sliding methods using appliances, body weight, or additional limbs. Common complications include injury, stiffness, infection, and pressure sores.
Mrs. B, a 65-year-old farmer, presented with sudden lower back pain and bilateral lower limb weakness. Imaging showed spondylodiscitis at D10-11. Blood cultures grew Pantoea agglomerans, an uncommon pathogen. She was treated with intravenous then oral ciprofloxacin for 6 weeks. Biopsy showed infective changes but was negative for tuberculosis. Her symptoms and inflammatory markers improved with antibiotics. Pantoea agglomerans is an opportunistic pathogen typically causing wound or urinary infections, and this represents a rare case of spondylodiscitis from this organism.
This document discusses inflammatory diseases of the bones and joints, focusing on osteomyelitis. It defines osteomyelitis as inflammation of all bone anatomical structures that is typically caused by common bacteria like Staphylococcus aureus. It describes the pathogenesis of hematogenous osteomyelitis, how it spreads through the bones, and can lead to complications like sepsis and fractures. Diagnosis involves x-rays and CT scans to identify features like periosteal reaction and bone destruction. Treatment involves antibiotics, surgery to debride infected areas, and managing complications.
This document provides an overview of bone tumors including:
- Definitions of bone tumors as abnormal bone cell growth that can be benign or malignant
- Classification systems that stage benign and malignant bone tumors based on factors like growth and spread
- Common clinical features of bone tumors like bone pain, lumps, fractures, and weight loss
- Diagnostic tests and treatment options for bone tumors including biopsy, imaging, chemotherapy, radiation, surgery and pain management
- Nursing considerations for patients with bone tumors which involve comprehensive assessment, developing a care plan and providing home care instructions.
This document provides an overview of bone tumors, including their definition, types, risk factors, clinical manifestations, diagnosis, and treatment. Bone tumors are abnormal bone growths that can be benign or malignant. Common types include osteosarcoma and chondrosarcoma. Risk factors include genetics, radiation exposure, and injuries. Symptoms may include pain, swelling, limited mobility. Diagnosis involves x-rays, bone scans, and MRIs. Treatment options are chemotherapy, radiation therapy, surgery such as amputation or reconstruction. Complications can include delayed healing, infections, and fractures. Prevention focuses on family history awareness, healthy lifestyle, and early diagnosis.
Concept Map of Syndrome of Inappropriate (ly high) Anti-Diuretic Hormone (SIADH)riddler2008
Optimized for the BlackBerry, iPhone, Windows mobile phone, Symbian smartphone screen as a reviewer on-the-go.
Write to riddler2008@msn.com for similar slideshows.
This document discusses bone tumors, including:
- Bone tumors can be benign or malignant and develop from uncontrolled cell division in bones. Common types include osteosarcoma, chondrosarcoma, and Ewing's sarcoma.
- Risk factors include genetic disorders, radiation exposure, and other cancers. Symptoms include bone pain, swelling, limited mobility, and pathological fractures.
- Diagnosis involves imaging like X-rays, CT, MRI and PET scans. Biopsies are also used to identify the tumor type and stage. Staging uses the TNM classification system to assess tumor size, spread to lymph nodes and distant organs.
Osteomyelitis is an infection of the bone that results in inflammation, necrosis, and new bone formation. It is classified as hematogenous, contiguous focus, or associated with vascular insufficiency. Staphylococcus aureus is the most common causative organism. Clinical manifestations include pain, swelling, and drainage from non-healing ulcers. Diagnosis involves imaging tests and biopsy. Treatment involves antibiotics, surgical debridement, and stabilization of the bone. Nursing care focuses on pain management, preventing complications like sepsis, and educating patients.
Drowning is a leading cause of accidental death in children worldwide. It occurs most commonly in males ages 1-5 years due to inadequate supervision near bodies of water. Drowning causes hypoxemia which quickly leads to respiratory and cardiac arrest. Survivors can have long-term pulmonary, neurological, cardiovascular and other injuries. Prompt rescue and resuscitation efforts on scene improve outcomes. In the hospital, management focuses on rewarming, correcting hypothermia, hypoxemia and other physiological derangements to prevent secondary neurological injury.
This document defines and describes near drowning, its causes, signs and symptoms, pathophysiology, diagnostic workup, and management. Near drowning occurs when a person suffers respiratory impairment from submersion in liquid. Common causes are accidents near water and inability to swim. Signs include cold skin, coughing, and shortness of breath. Pathophysiology involves involuntary inhalation of water leading to hypoxia, tissue damage, and cardiac issues. Diagnostic workup includes blood gases, imaging, and monitoring for arrhythmias and hypothermia. Management focuses on airway support, oxygen, treating hypothermia and hypoxia, and monitoring for pulmonary edema.
1. Drowning is defined as respiratory impairment from submersion in a liquid medium and is a major cause of accidental death, especially in children ages 1-14.
2. Management of drowning victims involves resuscitation, treatment of hypoxic-ischemic encephalopathy, and prevention of complications.
3. Prevention strategies focus on supervision during water activities, swimming lessons, CPR training, and safety measures around pools.
Let us lear about managing near drowning or submersion injury in children with PGY3 student , Dr Mohd Zahran Mohamed Zaki.
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This document discusses drowning, including statistics, risk factors, treatments, and the pathophysiology of drowning. It notes that drowning is the second leading cause of accidental death worldwide for children under 14. The pathophysiology of drowning is discussed, noting that regardless of whether saltwater or freshwater is inhaled, the outcome is hypoxemia and respiratory acidosis as surfactant is washed away and the lungs are unable to properly oxygenate blood. Prehospital treatments focus on providing oxygen and treating hypotension.
Drowning can cause hypoxic brain injury, pulmonary edema, hypothermia, and multi-organ dysfunction. Prognosis is poor if the victim was submerged for over 10 minutes, CPR lasted over 25 minutes, or their initial pH or core temperature was severely low. Prevention through supervision, CPR training, and lifejacket use is crucial to reducing drowning deaths and disabilities.
This document summarizes current concepts regarding drowning. It defines drowning as a process causing respiratory impairment from liquid submersion or immersion. Risk factors include male sex, young age, alcohol use, low income, lack of supervision, and aquatic exposure. Pathophysiology involves pulmonary injury from liquid inhalation and central nervous injury from hypoxia. Treatment involves pre-hospital CPR, maintaining airway and oxygenation in the emergency department, and monitoring for complications like sepsis or renal failure in the ICU. Prevention strategies are also discussed.
The document discusses shock, including its pathophysiology, classification, severity, consequences, and resuscitation. It aims to provide medical students an understanding of shock. Shock is defined as a systemic state of low tissue perfusion inadequate for cellular respiration. Different types of shock are classified including hypovolemic, cardiogenic, obstructive, distributive, and endocrine shock. The severity of shock ranges from compensated to decompensated to multiple organ failure. Consequences include cellular damage, organ dysfunction, and death. Resuscitation focuses first on fluid therapy and addressing hypovolemia, with vasopressors and inotropes as adjuncts depending on the shock type.
The document provides information on submersion injury or near-drowning, including definitions, epidemiology, pathophysiology, clinical manifestations, investigations, treatment procedures, prognosis, prevention measures, and a painting illustrating how quietly drowning victims are often discovered. It notes that drowning is a leading cause of injury death among children globally and in the Philippines specifically. The pathophysiology involves hypoxia from fluid aspiration into the lungs from submersion. Treatment involves aggressive warming, ventilation, and monitoring for complications like respiratory failure or multiple organ dysfunction. Prognosis depends on factors like response to resuscitation and neurological status upon arrival to emergency care.
This document summarizes guidelines for cardiopulmonary resuscitation (CPR). It discusses:
1) The sequence of steps for CPR has changed and is now CAB for all ages, even children and infants, with an emphasis on minimizing delays to chest compressions.
2) Recommendations for compressions in children include pushing hard and fast at a rate of 100-120 per minute to a depth of at least one third the chest diameter.
3) An automated external defibrillator (AED) can now be used for infants, starting with an initial shock of 2-4 joules.
4) Hypothermia treatment is recommended for comatose cardiac arrest patients
This document outlines the principles of pre-hospital and emergency department management of submersion and electrical injury patients. It discusses drowning as a leading cause of injury death worldwide, occurring most often in fresh water among males and children. Management of drowning victims involves establishing airway, breathing, circulation, warming and treating for hypothermia. Complications can include hypoxic brain and lung injury. Electrical injuries vary in severity depending on voltage, amperage and current type. Direct current injuries from lightning typically cause instantaneous asystole while alternating current may induce ventricular fibrillation. Principles of electrical injury management involve evaluating for burns, arrhythmias and multi-organ involvement.
Sudden cardiac death is defined as an abrupt loss of consciousness within one hour of the onset of symptoms due to a cardiac cause. The main risk factors include age, race, sex, hereditary factors, lifestyle like smoking and obesity, left ventricular dysfunction, and ventricular arrhythmias. The most common causes are coronary artery disease, cardiomyopathies, acute heart failure, and electrophysiological abnormalities. Management of cardiac arrest focuses on continuous cardiopulmonary support, early defibrillation if needed, advanced life support including intubation, medications, and post-cardiac arrest care like therapeutic hypothermia. The goal is to restore spontaneous circulation and hemodynamic stability through these interventions.
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive function. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms.
Emergency care and First aid: Mastering First Aid Skills for Emergency ResponseRagulRagul19
First aid is the immediate and initial care provided to a person who has been injured or suddenly taken ill. It aims to preserve life, prevent the condition from worsening, and promote recovery. Essential components include assessing the situation, contacting emergency services, performing CPR if necessary, controlling bleeding, and addressing minor injuries. First aid knowledge is crucial for everyone, as it empowers individuals to respond effectively in emergencies until professional medical help arrives.
This document discusses pediatric drowning. It begins with terminology used in drowning and then covers epidemiology, noting it is a leading cause of death worldwide in boys aged 5-14 and the second leading cause of death in US children aged 1-4. Mechanisms, injuries, and presentations are described for different age groups. Pathophysiology explores effects of drowning on the lungs, brain, and autonomic function. Pre-hospital care emphasizes removing the child from water and starting CPR. The trauma evaluation and treatments in the emergency department are outlined. Prevention strategies target fencing pools for toddlers and supervision for children, while advising life jackets and avoiding alcohol for adolescents.
Stroke is a leading cause of death and disability globally. The presentation summarizes key aspects of stroke management. It describes the epidemiology, pathophysiology, clinical features, diagnosis and management of both ischemic and hemorrhagic strokes. Prevention of initial and recurrent strokes is emphasized through control of risk factors and use of anticoagulants or antiplatelets depending on the patient's risk profile. Early diagnosis and treatment including thrombolysis are important to minimize brain damage from acute strokes.
Similar to Environmental Medicine drowning and electrical injuries.pptx (20)
DECLARATION OF HELSINKI - History and principlesanaghabharat01
This SlideShare presentation provides a comprehensive overview of the Declaration of Helsinki, a foundational document outlining ethical guidelines for conducting medical research involving human subjects.
Test bank for karp s cell and molecular biology 9th edition by gerald karp.pdfrightmanforbloodline
Test bank for karp s cell and molecular biology 9th edition by gerald karp.pdf
Test bank for karp s cell and molecular biology 9th edition by gerald karp.pdf
Test bank for karp s cell and molecular biology 9th edition by gerald karp.pdf
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
Co-Chairs, Val J. Lowe, MD, and Cyrus A. Raji, MD, PhD, prepared useful Practice Aids pertaining to Alzheimer’s disease for this CME/AAPA activity titled “Alzheimer’s Disease Case Conference: Gearing Up for the Expanding Role of Neuroradiology in Diagnosis and Treatment.” For the full presentation, downloadable Practice Aids, and complete CME/AAPA information, and to apply for credit, please visit us at https://bit.ly/3PvVY25. CME/AAPA credit will be available until June 28, 2025.
Travel vaccination in Manchester offers comprehensive immunization services for individuals planning international trips. Expert healthcare providers administer vaccines tailored to your destination, ensuring you stay protected against various diseases. Conveniently located clinics and flexible appointment options make it easy to get the necessary shots before your journey. Stay healthy and travel with confidence by getting vaccinated in Manchester. Visit us: www.nxhealthcare.co.uk
Promoting Wellbeing - Applied Social Psychology - Psychology SuperNotesPsychoTech Services
A proprietary approach developed by bringing together the best of learning theories from Psychology, design principles from the world of visualization, and pedagogical methods from over a decade of training experience, that enables you to: Learn better, faster!
Breast cancer: Post menopausal endocrine therapyDr. Sumit KUMAR
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
5-hydroxytryptamine or 5-HT or Serotonin is a neurotransmitter that serves a range of roles in the human body. It is sometimes referred to as the happy chemical since it promotes overall well-being and happiness.
It is mostly found in the brain, intestines, and blood platelets.
5-HT is utilised to transport messages between nerve cells, is known to be involved in smooth muscle contraction, and adds to overall well-being and pleasure, among other benefits. 5-HT regulates the body's sleep-wake cycles and internal clock by acting as a precursor to melatonin.
It is hypothesised to regulate hunger, emotions, motor, cognitive, and autonomic processes.
These lecture slides, by Dr Sidra Arshad, offer a simplified look into the mechanisms involved in the regulation of respiration:
Learning objectives:
1. Describe the organisation of respiratory center
2. Describe the nervous control of inspiration and respiratory rhythm
3. Describe the functions of the dorsal and respiratory groups of neurons
4. Describe the influences of the Pneumotaxic and Apneustic centers
5. Explain the role of Hering-Breur inflation reflex in regulation of inspiration
6. Explain the role of central chemoreceptors in regulation of respiration
7. Explain the role of peripheral chemoreceptors in regulation of respiration
8. Explain the regulation of respiration during exercise
9. Integrate the respiratory regulatory mechanisms
10. Describe the Cheyne-Stokes breathing
Study Resources:
1. Chapter 42, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 36, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 13, Human Physiology by Lauralee Sherwood, 9th edition
Summer is a time for fun in the sun, but the heat and humidity can also wreak havoc on your skin. From itchy rashes to unwanted pigmentation, several skin conditions become more prevalent during these warmer months.
low birth weight presentation. Low birth weight (LBW) infant is defined as the one whose birth weight is less than 2500g irrespective of their gestational age. Premature birth and low birth weight(LBW) is still a serious problem in newborn. Causing high morbidity and mortality rate worldwide. The nursing care provide to low birth weight babies is crucial in promoting their overall health and development. Through careful assessment, diagnosis,, planning, and evaluation plays a vital role in ensuring these vulnerable infants receive the specialize care they need. In India every third of the infant weight less than 2500g.
Birth period, socioeconomical status, nutritional and intrauterine environment are the factors influencing low birth weight
3. DROWNING
DEFINITION
• Drowning is defined as respiratory impairment resulting from submersion in a liquid
medium
• Drowning can be nonfatal (also called near drowning) and fatal
• About 4 times as many people are hospitalized for nonfatal drowning as far fatal
drowning
• Intentional use of drowning (water boarding) in humans is unethical and is classified as
torture in Geneva Conventions
4. Introduction
• Generally, drowning accidents results in asphyxiation & hypoxia, which can damage
multiple organs and lead to death if the victim is not rescued
• In the adults, drowning is common in pools, hot tubs, and natural water settings
• Among infants and toddlers, drowning is common in toilets, bathtubs and buckets of
water
5. Epidemiology of drowning
• WHO estimates 380,000 drowning deaths worldwide each year
• 1st cause of accidental deaths in preschoolers
• 2nd most common cause of accidental death in school-age children ages <14yrs
(particularly in ages <4yrs)
• Overall, drowning is the 3rd leading cause of accidental death in the US
• >50% of drowning leading to deaths occur in swimming pools
6. Epidemiology of drowning
• Children aged 1-4yrs often drown in swimming pools
• Infants <1yr usually drown in bathtubs
• Children >15yrs, 65% of drowning occur in natural water (river, lakes, ponds,
oceans)
• Alcohol is a factor in >50% of adolescents & adults drowning deaths
• About 4 times as many people are hospitalized for non-fatal drowning as for fatal
drowning
7.
8.
9.
10. Risk factors for drowning
• Infants & Children
– Lack of adequate supervision of children in bathtubs & swimming pools
– Child abuse/neglect
– Lack of life jackets in swimming venues
– Children <4yrs
– African-American/Immigrant families
11. Risk factors for drowning
• Teenagers & Adults
– Males > Females
– Alcohol abuse
– Inability to swim
– Fatigue/exhaustion when swimming
– Suicide attempts
– Medical emergency in water
• Myocardial infarction, seizures, hypoglycemia, fatigue or exhaustion in water
– Lack of life jackets in swimming venues
– Known or unknown Long QT syndrome (LQT1)
12. Drowning types
• Drowning is classified into 2
– Wet drowning (80-90%)
• There is aspiration of water into the lungs
– Dry drowning (10-20%)
• There is no aspiration of water into the lungs
• There is reflex laryngeal spasm
• There is no clinical difference in prognosis, treatment and outcome between wet &
dry drowning
13. Pathophysiology of Drowning/The ‘drowning’ sequence
– Drowning victims are always terrified & they struggles to keep his/her head
above the water
– After the head submerges or drops below the water surface, breath holding occurs
– The overwhelming sympathetic overdrive with breath holding causes the larynx
to go into spasm
– Most often (80-90%) the laryngeal spasm relaxes allowing water through the
larynx into the lungs(wet drowning)
– Approximately 10-20% of drowning victims have persistent laryngeal spasm and
no fluids is found in the lungs at autopsy (dry drowning)
15. Pathophysiology of Drowning/The ‘drowning’
sequence
• The overall mechanism of demise from drowning is via larngeal spasm leading to
asphyxiation which subsequently precipitates respiratory arrest & cardiac arrhythmia
leading to death
• The brain stops functioning with permanent cortical damage occurring within 4-
6mins if not rescued
16.
17. Pathophysiology of Drowning
Hypoxia & Metabolic acidosis
1. Asphyxiation from laryngeal spasm of drowning leads hypoxia.
2. Immediate hypoxia occurs from aspiration of water.
3. Fresh/sea water aspiration destroys pulmonary surfactant leading to alveolar collapse,
V/Q mismatch & hypoxemia
4. Aspiration of hypertonic sea water pull additional fluid into the alveoli leading to
alveolar edema with further V/Q mismatch
5. Generalized tissue hypoxia leads to metabolic acidosis
Hypothermia (temperature < 35°C)
1. Exposure to cold water leads to systemic hypothermia. Systemic hypothermia can be
initially protective by stimulating the mammalian diving reflex slowing the heart beat
and constricting the peripheral blood vessels shunting oxygenated blood away from
the extremities and the gut to the heart and brain possibly prolonging survival and
delaying the onset of hypoxic tissue damage.
2. Prolonged hypothermia becomes deleterious to the tissues
18. Pathophysiology of Drowning
Fluid aspiration
1. Enough large volume of fluid are sometimes aspirated to cause change in
blood volume and electrolyte concentraions
2. Sea water aspiration may increase Na and Cl slightly. Large volume of
aspirated fresh water can decrease electrolyte concentration significantly to
cause hemolysis
Associated injuries
1. It is important to look for skeletal, soft tissue, head and internal injuries in
drowning victims.
2. People who dive into shallow water may sustain cervical and other spine
injuries
19. Symptoms & Signs of Drowning
– Panic+++
– Air hunger
– Tachypnea
– Chest retractions
– Cyanosis
– After rescue
• Anxiety, vomiting, wheezing, altered consciousness
20. Diagnosis of Drowning
• Most people are FOUND IN OR NEAR WATER making the diagnosis obvious
clinically
• Cervical spine injury is assumed especially if there is history of diving into shallow
water
• Sometimes respiratory symptoms are delayed until several hours after
submersion/drowning episode
21. Investigation of Drowning victims
Investigations are to identify complications/associations of Drowning
• Pulse oximetry to determine the severity of asphyxia/hypoxia
• Body temperature to rule out hypothermia
• Random Blood Sugar to rule out hypoglycemia
• Arterial Blood Gas if oximetry is abnormal
• ECG to rule out presence of arrhythmia/LQT syndrome in patient who drown
without apparent risk factors
• Cardiac Enzymes
• CXR
• Cervical Spine Xray
• EUCr
22. Treatment of Drowning patients
• All patients are to the transported to the hospital and observed for several 12-24hrs
because respiratory symptoms can be delayed
• Hospital admission is recommended except in patient with mild symptoms and normal
oxygenation in the emergency
• Initiate Resuscitation measures immediately
– Airway
– Breathing
– Circulation
– Core Body temperature
23. Treatment of Drowning patients
• Reverse hypoxia with 100% Oxygen via facemask or Endotracheal tube placement
ASAP and titrate with oximetry
• Warm hypothermic patients with aluminium foil ASAP
• Mechanical ventilation with PEEP/IPPV to expand collapsed alveoli (atelectasis) to
aid resolution of pulmonary edema
• Nebulized β2 agonists to reduce bronchospasm & wheezing
• Antibiotics in patients with bacteria pneumonia from aspiration
24. Prognosis of Drowning
• Depends on timeliness of rescue
• Effectiveness of emergency response
• Rapid institution of resuscitation (most important factor) (good prognosis)
• Brief duration of submersion (good prognosis)
• Young age (good prognosis)
• Cold water temperature (mammalian diving reflex) (good prognosis)
26. Prevention of Drowning
• Don’t use alcohol/drugs before or during swimming
• Children or inexperienced swimmers should swim in guarded/supervised areas only
• Children <4yrs, swimming lessons not recommended
• Household swimming pools should be surrounded by a gated fence >1.5m
• Elderly people with debilitating illness that can alter consciousness should take extra
precautions during swimming
28. Electrical Injury
• Electrical injury is tissue or organ damage caused by generated electrical current
passing through the body
• Accidental electrical injuries in the home rarely result in significant injury or sequele
• However, accidental exposure to high voltage in the workplace causes about 400
deaths in the USA
• Electrocution is the killing of a person with passage of high voltage current through
the body
29. People in which electrical injury are exceptionally
dangerous
• Persons with Arrhythmia
• Persons with Chest pain
• Persons with known or risk with of heart disorders
• Pregnant patients
30. Pathophysiology of Electrical Injury
• Traditionally, the severity of electrical injury depends on
Kouwenhoven’s factors
– Type of current (DC/AC)
• AC is 3-5 times more dangerous compared to DC for the same voltage & amperage
– Voltage & amperage
• Measures of current strength
– Duration of exposure
• Longer duration increases injury severity
– Body resistance
– Pathway of current
• Determines the specific tissue damaged
• Electrical field strength (a newer concept) seems to predict injury
severity more accurately
31.
32. Pathology of Electrical Injury
• Application of low electrical field strength causes immediate unpleasant feeling of
being ‘shocked’ but seldom results in serious or permanent injury
• Application of high electrical high strength may cause thermal or electrochemical
damage to internal tissues e.g.
– Hemolysis
– Tissue protein coagulation
– Muscle necrosis/swelling
– Tissue destruction &
– Ventricular fibrillation
40. Treatment of Electrical Injuries
• First priority is to break contract between the person & the current source by
shutting off the current
• Resuscitation
• Analgesics
• Cardiac monitoring for 6-12hrs
• Wound care of Burns
41.
42.
43. Prevention of Electrical Injury
• Electrical devices should be properly insulated and grounded
• Incorporate protective ground fault circuit breakers which trip when as little as
5mA of current leaks into the ground
• Outlet guards reduces risks in home with infants and children