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ENDOCA PRESENTAZIONE AZIENDA E PRODOTTI NATURALI BIO DELLA CANAPA - CBD >> By PuntoG
1.
2.
3. 3
LETTER FROM “THE FIELDS” .........................................................................................................................5
OUR VISION ...........................................................................................................................................................7
OUR FIELDS ..........................................................................................................................................................9
CBD EXTRACTION ..............................................................................................................................................11
THE PRODUCTS .................................................................................................................................................13
CBD OIL DROPS ..................................................................................................................................................15
CBD PASTE ...........................................................................................................................................................17
CBD CAPSULES .................................................................................................................................................19
CBD SUPPOSITORIES .....................................................................................................................................21
CANNABIS CRYSTALS ....................................................................................................................................23
CBD SHISH ..........................................................................................................................................................25
CBD CHEWING GUM ........................................................................................................................................27
WHOLESALE .....................................................................................................................................................28
DO YOU REALLY KNOW WHAT IS IN YOUR CBD OIL? ........................................................................30
HEMP VS. CANNABIS .....................................................................................................................................32
ABOUT CBD & CBDA .......................................................................................................................................33
CBD THERAPEUTIC AREAS .........................................................................................................................34
MISSION ...............................................................................................................................................................37
ENDOCA VILLAGE ...........................................................................................................................................38
Table of contents
4.
5. “When I started working with cannabis in 2006 there
were no other companies producing CBD. Today there
are several companies manufacturing CBD but many
are compromising on quality to save costs. In addition
there are many online companies that sell CBD by re-
branding cheap, low quality CBD extracts to increase
their margins.This influx of newcomers attracted
by the high profit margins and lack of regulation has
made it difficult for consumers to find high quality CBD
products.
The amount of mis-information and pseudo scientific
jargon being thrown around has also angered the
existing medical community and caused concern
for the pharmaceutical industry who want the
government to regulate and stifle this emerging
market.
It’s a great opportunity and a great challenge for
Endoca to continue innovating and pushing the
standards higher, setting the bar for others to follow.
As the leaders in cannabinoid production and research
we feel it’s our duty to educate and work together with
other companies and government regulatory bodies
while informing the consumer about CBD oil and it’s
revolutionary applications in medicine.”
Henry Vincenty
CEO Endoca
Letter from “the fields”
6.
7. 7
At Endoca we are leading the revolution in plant based
medicine, unlocking the secrets of nature and setting
the gold standard in the cannabis industry for natural,
pharmaceutical-grade products made from hemp.
(Cannabis Sativa L.)
Endoca has a long-standing family tradition of growing
and cultivating the finest hemp in the world. Henry
Vincenty, the founder of Endoca, discovered many
ways hemp plants could be used as native, holistic,
and natural health aids and using his training in organic
chemistry and botany, he developed Endoca CBD oil
extracts using the versatile and eco-friendly hemp
plant that his family had grown for generations.
Today our primary focus is to research and develop
innovative hemp extracts and to make them
accessible worldwide. We are dedicated to producing
the finest and purest quality CBD.
Our primary goal is to develop high quality hemp
extracts with a broad profile of cannabinoids and other
natural molecules found in hemp and to identify their
distinct properties.
In the near future Endoca
products will be high in
CBD but with 0% THC.
CBD products will be sold in
stores around the world,
just like typical vitamins
and supplements.
Our Vision
8.
9. 9
Endoca extracts CBD oils from hemp plants grown
and cultivated organically without herbicides or
pesticides.
Our hemp grows in Denmark, one of the top ten
countries in Europe for organic share of the total
cultivated area. The low lying and relatively flat land
in Denmark added to the existing fertile soils, and
partially favorable climate (winter frost + warm and
sunny summer with rainfall over the average) makes
Denmark ideal for hemp farming.
Denmark’s many years of experience has created a
unique management/quality system in the country,
which is highly systematised and coordinated in it’s
efforts to handle soil and groundwater contamination.
Regulations in Denmark have long since made soil
quality an area of great consideration for hemp
production.
Endoca begins with the best seeds nature can create
for CBD production. Our non-GMO organically grown
hemp plants are gently harvested and dried under
the most optimal natural conditions. The hemp
harvest at Endoca employs the most dedicated staff
and advanced tools in the world, above and beyond
those commonly available in the hemp industry
and including custom made technologies especially
developed for optimal CBD hemp farming.
Our Fields
10.
11. 11
CBD extraction
Endoca capacity:
2015, 100ha cannabis
2016, 500ha cannabis
2017, 1000ha cannabis
Endoca’s factory is capable of producing many
different GMP certified cannabinoids, on industrial
scale.
Generally, there is a lack of consistent quality control
in the hemp industry. There are no standards or
objective, professional, appropriately trained third
parties regulating the cannabinoid industry, even
though many believe there are. Legislators are relying
on cannabis hobbyists or under-qualified scientists
often with no background in the botanical science of
the cannabis plant or in food safety – to determine
standards for this massive new industry.
Most laboratories have limitations and difficulties
conducting reliable quality testing on cannabis,
limitations that can only be remedied by significant
investment in both emerging high technology and
experienced organic chemists.
Unfortunately, many products on the market
contain residual pesticides, herbicides, mold, fungi,
heavy metals, and even dangerous and overlooked
mycotoxins. Yet few are willing to invest in cutting-
edge analytics because the public is largely unaware
of dangerous lapses in cannabis product quality
rampant in the industry today.
Understanding this sad fact of life in the cannabis
industry, we have invested enormous amounts of
time and resources into our extraction methods,
quality assurance and quality control. Constant
improvement is our goal to ensure precision, accuracy,
and repeatability in our extraction and product testing
approaches.
Quality control is central to Endoca’s quest to bring
our customers the very best CBD and hemp products
nature and science can offer. It’s why we follow strict
pharmaceutical industry standards throughout our
entire production process.
Every batch of hemp oil created at Endoca is tested
thoroughly to ensure that our organic products are
free from pesticides, herbicides, molds, heavy metals,
and other common contaminants. We utilize HPLC,
an industry standard, as well as an advanced nuclear
magnetic resonance (NMR) technology to monitor the
oil composition at all points in the production process.
We go this extra mile to provide our customers
with peace of mind and confidence that they have
purchased the finest quality hemp products in the
world.
Our laboratory analysis is certified and
standardised according to the following
protocols:
ISO 14001: 2004 certified
ISO 9001: 2008 certified
HACCP certified
GMP certified
13. 13
Through a unique extraction process, Endoca
reproduces the natural, balanced phytochemical
profile of the original dry cannabis material. Endoca
believes that the biochemical equilibrium within the
herb must be maintained since this has proven to be
effective throughout the ages to heal the body and
promote good health.
To ensure the quality of our products we currently
screen for over 300 pesticides, heavy metals, and
mycotoxins. While we use equipment unavailable
to most, every batch of product is verified by
independent GMP certified labs that crosscheck our
results.
We do all of this because our mission at Endoca is
to lead the hemp and cannabis industry, becoming
the gold standard for hemp analytics and quality
assurance, so that more people will benefit from the
therapeutic properties of cannabinoids. We do this
knowing that when we raise the bar for quality, the
benefits of our mission are shared with all current and
future hemp and cannabis product users.
The products
14.
15. 15
Available as:
(3%) 300mg CBD (3%) 300mg CBD+CBDa (15%) 1500mg CBD (15%) 1500mg CBD+CBDa
SIMPLE AND EFFECTIVE
Our CBD Oil Drops are an
easy way to administer
and consume CBD.
The absorption rates are
much higher when hemp
oil is taken in a liquid
form. For this product
CBD is diluted in
organic hemp seed oil
rich in Omega 3 and 6.
CBD Oil Drops
16.
17. 17
CBD Paste
Available as:
(20%) 2000mg CBD (20%) 2000mg CBD+CBDa (30%) 3000mg CBD (30%) 3000mg CBD+CBDa
CONCENTRATE
CBD extract is the classic
way of consuming CBD.
Known for its great
paste consistency, our
CBD extract also has a
unique flavor and a very
high concentration of
CBD and other
Phytocannabinoids.
18.
19. 19
CBD Capsules
Available as:
300mg CBD 300mg CBD+CBDa 1500mg CBD 1500mg CBD+CBDa
BEST FOR
PRECISE DOSING
Capsules are ideal for
precise dosing of CBD.
Vegan gel caps, gluten-
free and completely ko-
sher. They’re extremely
easy to swallow due to
their smooth texture and
they are also odorless
and tasteless.
20.
21. 21
CBD Suppositories
For people suffering from nausea, vomiting or a gastrointestinal condition,
oral consumption may not be suitable. In that case, our CBD suppositories are a great
alternative administration method.
BEST ABSORPTION RATE
- 10 suppositories 50mg cbd per suppository
Ingredients: Organic Raw Cannabis Sativa Extract, Coconut oil.
22.
23. 23
Cannabis Crystals
Pure 98% CBD(Cannabidiol), 0%THC. The purest Cannabidiol extract ever created.
Extracted using Supercritical CO2, Solvent free and lab tested.
Mix it with your flower, dab it pure or add it to tinctures.
PUREST EXTRACT
- 1 jar: 500mg CBD
ingredients: Pure 98% CBD (Cannabidiol), 0%THC
24.
25. 25
CBD Shish
CBD Shish, ideal to mix with your herbs or dab it pure using a vaporizer.
CBD evaporates above 180°C (356°F)
NEW CBD TO VAPORIZE
- 1 jar: 2g of CBD Shish for a total of 140mg CBD.
ingredients: organic plant material,CBD (Cannabidiol)
26.
27. 27
CBD Chewing Gum
Chewing gum increases the bioavailability of CBD.
Old traditional recipe. Made with natural chicle gum from the rain forest and without
the use ofsynthetic ingredients.
HIGH BIOAVAILABILITY
- One box contains 10 pieces of gum (150mg CBD)
- 15mg CBD per gum
ingredients: Chicle gum base, xylitol, CBD extract,
peppermint, menthol, sunflower lecithin.
28. 28
Wholesale
The Cannabis extracts we create can be divided into
different categories depending on the process that it
went through. Depending on what product you want to
formulate different types of extracts have different
advantages.
CO2 EXTRACTION (First Extract)
We extract cannabis using CO2 and this results in an
extract that’s solid like a paste. The extract from the
first extraction is a thick, golden-brown colored paste.
The extraction can vary in % of CBD and CBDa from
3%(CBD) to 30%(CBD).
As standard we provide you with: 7%(CBD) or 7%
Raw(CBD+CBDa) . The reason that we make 7% as
a standard is that the THC content is then is under
0.2% and it’s possible to make a standard product in
large quantities very easily. If you have special needs
for this type of product lets us know as there are
possibilities to make the % of CBD or CBDa higher.
The First extract can be divided in 2 groups according
to the viscosity:
COLD FILTERED EXTRACT
The extract contains many waxes that makes the
product like a paste. To remove the waxes we have
two different approaches we call filtration:
1.Cold filtration & 2.Hot filtration
In Cold filtration we work with low temperatures and
remove 1 type of waxes from the first extract, the
result from this is more loose extract with a lower
viscosity we call cold filtered cbd extract. Because
the viscosity is lower the product is more liquid and
makes it possible to mix it with other products easily
and keep the end product more liquid. The cold filtered
cbd extract can vary in % of CBD and CBDa from 10%
to 50%. As standard we provide you with: 20%(CBD)
or 20% Raw(CBD+CBDa) . If you have special needs
for this type of product lets us know as there are
possibilities to make the % of CBD or CBDa higher.
First Extraction
(solid)
Cold Filtred Extract
(extra liquid)
Cold Filtred Extract
(liquid)
29. 29
The Cold filtered extract can be divided in 2 groups
according to the viscosity:
HOT FILTERED EXTRACT
“Golden CBD Oil”
We work with higher temperatures and remove
another type of waxes from the cold filtered cbd
extract, the result from this is a more loose extract
with lower viscosity we call hot filtered cbd extract
or “the golden oil”. The viscosity is lower than the
first CBD extraction but higher than in the cold filtered
cbd extract. The texture is more like coconut oil as it
becomes liquid when the temperature is high and solid
when temperature is below 20°C. The hot filtered cbd
extract can vary in % of CBD and CBDa from 10% to
50%, as standard we provide you with: 20%( CBD)
or 20% Raw(CBD+CBDa) If you have special needs
for this type of product lets us know as there are
possibilities to make the % of CBD or CBDa higher.
99% CBD (Pure CBD)
By means of continuing the filtration process of our
extracts we produce our 99% pure CBD, which can be
used in various production applications. As an example
we normally mix our extracts with organic hemp seed
oil to loosen up the material. For vape products we
recommend that you use 99% CBD.
Hot Filtered Extract
(solid)
Hot Filtered Extract
(liquid)
Hot Filtered Extract
(extra liquid)
99% Pure CBD
30. 30
Unfortunately the majority of Cannabis extracts are
produced without access to the proper laboratory
equipment and many manufacturers use toxic
solvents in the extraction process that leave residues
in the product. Besides the leftover chemicals from
the extraction process, many products on the market
may contain toxins such as pesticides, heavy metals,
herbicides, e-coli, mold fungi and even dangerous but
overlooked mycotoxins.
You may get an upset stomach, find that your CBD oil is
ineffective or even poison yourself with carcinogens
over time when using uncertified CBD oil that has not
been produced with conscientious attention to it’s
quality.
It takes the right plant
There are many ways to improve production and yields
and among these is the use of chemical fertilizers and
pesticides. We all know that these methods are bad
for us, and we could even turn a blind eye if the hemp
is used for fiber production, but when you are going
to consume a plant as food or even more importantly,
use it as a medicine, this is simply unacceptable.
These chemicals will be concentrated in oil extracts
and when these are ingested, they could even be lethal.
Luckily, there are ethical companies such as Endoca,
who have chosen to produce their hemp oil organically
and use the cleanest and most advanced methods of
extraction available today.
Do I chose Synthetic CBD
or natural CBD?
How much CBD is in the bottle? This appears to be
a simple question, but in the absence of regulation,
supplement manufacturers can print any fiction they
want on the product label.
Do you really know what is
in your Cannabis extract?
Can CBD be
dangerous?
Choose only
organic hemp
Fake CBD
percentages %
31. 31
How do we know we can trust a
CBD manufacturer?
These are the most important points to look out for:
• Batches are tested internally, but also by an impartial
third party and these results are made public.
• Good Manufacturing Practices (GMP) certification.
• International Organization for Standardization
(ISO) certification.
• Accessible, contactable customer care service.
GMP certification
Good manufacturing practices (GMP) are the practices
required in order to conform to the guidelines
recommended by agencies that control authorization
and licensing for manufacture and sale of food, drug
products, and active pharmaceutical products. These
guidelines provide minimum requirements that a
pharmaceutical or a food product manufacturer must
meet to assure that the products are of high quality
and do not pose any risk to the consumer or public.
Ask the CBD oil producer for the GMP certificate
number if they have one!
Fake CBD
Synthetic production of CBD is easy and profitable.
There’s just one problem: it doesn’t work! It may
seem chemically similar, but it won’t be helpful as a
treatment and could even be dangerous. Studies show
that whole plant CBD is the only effective form of CBD.
How can I choose a good CBD oil?
• The producer is GMP certified
• online batch test results
• Transparent information and 3rd party lab tests
are available
• The producer works from seed to shelf maintaining
100% control over the entire production process.
• Organic production methods have been employed.
• The brand has a trusted status among other
consumers.
tested by
3rd party labs
Endoca is
GMP certified
Choose only
a trusted CBD
source
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What’s The Difference
Both are actually Cannabis plants, however Hemp
or industrial Hemp is a commonly used term for
cannabis plant strains that contain very low levels
of Tetrahydrocannabinol (THC) and are used for it’s
fiber and seeds. Cannabis use was identified in ancient
villages from over 10.000 years ago in Asia placing it
as one of the first humanly cultivated plants
What molecules does
cannabis contain?
There are over 480 natural components found within
the Cannabis plant. The molecules that recently got
most attention are cannabinoids At least 85 different
cannabinoids have been isolated from the Cannabis
plant. However there are other molecules: Terpenes,
Chlorophyll, Alkanes, Nitrogenous compounds,
Amino acids, Sugars, Aldehydes, Alcohols, Ketones,
Flavonoids, Glycosides, Vitamins, Pigments.
Why are cannabinoids so
interesting?
Our bodies create cannabinoid like substances
and we call them endogenous cannabinoids or
endocannabinoids. Plants make similar cannabinoids
and they are called phytocannabinoids.
Hemp vs. Cannabis
33. 33
CBD
The cannabis plant contains many different
cannabinoids,We have seen over 80 different types
and it seems there are many more. Most people
have heard of a cannabinoid called THC, which is the
ingredient in cannabis that gets users high. Unlike
THC, CBD is a non¬psychoactive cannabinoid and does
not cause a high. CBD has antipsychotic effects which
means CBD works completely the opposite way of
THC. Numerous studies suggest that CBD also acts
to reduce the intoxicating effects of THC, such as
memory impairment and paranoia.
CBDa
In nature CBD and THC are found mostly in their acid
form: CBD as CBDa and THC as THCA.
The plants actually contain very little CBD or THC.
What’s most remarkable is that if you eat the plant
raw, as nature intended, you will not get the the
psychoactive side effect as THCa is non-psychoactive.
The reason is that you need to heat THCa in order to
turn it in to THC. Historically, dietary use of the entire
raw cannabis plant brings us back to the beginning of
the human race.
Oils containing different forms of CBD have been
found to work much better the CBD alone.
About CBD CBDa
34. 34
The endocannabinoid system (ECS) is a lipid-derived
signaling system discovered within the past decade.
Cannabinoids, which are homeostatic regulators,
circulate throughout human and animal systems
continuously, affecting all physiological processes.
The endocannabinoid system is comprised of CB1 and
CB2 receptors which bind directly or indirectly to
cannabinoids and phytocannabinoids, CB1 receptors
are excitatory and are located n the central nervous
system, lungs, liver, and kidney. CB2 receptors
regulate immunological responses and are located in
the immune and circulatory systems.
Endogenous compounds, such as anandamide and
arachidonylglerol (2-AG), are made by mammals from
lipids and bind directly to the CB1 and CB2 receptors,
serving as neurotransmitters for cannabinoids.
Cannabidiol (CBD oil), a non-psychotropic cannabinoid
naturally occurring in human and animal species,
it’s also a phytocannabiniod, derived from the
industrial hemp plant . While CBD does not bind
directly with receptors, it does affect stress genes,
such as Soat2 and Cyp27a1, which control sterol (i.e.,
cholesterol) metabolism. CBD increases the amount
of anandamide and other vital lipids, thereby indirectly
increasing the availability of circulating cannabinoids
to bind with CB1 and CB2
receptors. Research has shown that cannabidiol in the
form of CBD oil has therapeutic benefits
individually and adjunctively with other interventions,
Cannabidiol (CBD) made from legal, industrial hemp
contains less than 0,3% THC, rendering it
non-psychoactive. CBD oil has antiemetic, antioxylitic,
antitumoral, and immunologically inhibitory
properties.
Three categories differentiate the types of clinical
endocannabinoid deficiency (CECD) which are
associated with different disease processes
and disorders: genetic, acquired, and idiopathic
autoimmune. Many disorders have a combination of
CECD origins, and supplementation with cannabidiol
(CBD) requires ongoing assessment to facilitate
optimal benefit for the individual.The pandemic of
obesity is directly related to the dysregulation of the
endocannabinoid system among humans throughout
the world. Metabolic syndrome, obesity, insulin
resistence and the associated diseases have escalated
over the past two decades.
Visceral fat, which is an indicator of inflammatory
processes affecting the gastrointestinal system,
and endocannabinoid receptor dysfunction, and
associated endocannabinoid depleteion, accumulates
as substances foreign to the human gastrointestinal
system, are repetitively ingested, for example,
processed foods containing synthetic sugars increase
abdominal visceral fat as the body produces a rapid
inflammatory response via the immune system,
which is governed by the endocannabinoid
system. In the presence of adequate
endocannabinoids, the immune system response is
CBD - Therapeutic Areas
35. 35
modified, and excessive inflammation does not occur.
However, because synthetic food substances block
endocannabinoid production and therefore alter
CB1 and CB2 responses, the immune response is
excessive inflammation around the intestinal tract and
intrabdominal cavity becomes expansive.
This phenomenon, repeated on a daily basis, leads to
metabolic syndrome and obesity, directly associated
with insulin resistence, leading to diabetes mellitus.
In light of the recent research on the role of the
endocannabinoid system as the core center for
human and mammalian system regulation, education
becomes imperative to prevent and reverse behaviors
which contribute to metabolic dysregulation.
Exercise is essential for the function of physiological
systems in the human body. The effects are clearly
documented throughout countless studies. The
effects of exercise, however, even in the presence of
reduced caloric intake, do not correlate with weight
loss or, most importantly, the loss of visceral fat.
The endocannabinoid system requires the presence of
adequate cannabinoids for metabolic balance
and the reduction of visceral fat, associated with
gastrointestinal inflammation. Because dietary
intake of phytocannabinoids, which effectively balance
the endocannabinoid system, are severely
inadequate in the diets of developed countries
throughout the world, cannabidiol (CBD oil), as a
food, is suggested, in combination with the elimination
of synthetic food derivatives, as an adjunctive option
to manage obesity and associated disorders.
In a recent study, Cannabinoid Research Group (Reillo,
2015) established the correlation of the increased
measurement of salivary nitric oxide after use of
cannabidiol.
Nitric oxide levels in the human body are associated
with multiple cardiovascular, immunological,
metabolic, and neurological functions, with depletion
directly associated with endocannabinoid dysfunction.
Optimal levels are correlated with adequate
phytocannabinoid intake and endocannabinoid
system health.
The validation in human subjects of measuring the
effect of cannabidiol as an expression of nitric oxide is
significant as an assessment tool in the management
of an individual by the health care practitioner and
renders validation of the quality of the CBD
preparation recommended for use under the guidance
of the health care practitioner.
CBD interacts and modulates with the human
endocannabinoid system, their endogenous
activators (ligands), enzymes, and transporters. In
addition, cannabinoids interact with other important
neurotransmitter systems, along with the TRP
Channels.
CBD proves to be effective in diverse therapeutic
areas. Some of the major pharmacological effects
include :
• Anti inflammatory
• Increases drug uptake
• Biochemical pathways associated with diabetes
• Anti-psychotic
• Reduce anxiety and depression
• Regulate obesity
• Anti epileptic
•Anti neoplastic agent
36.
37. 37
Endoca vision - CBD hemp oil
opens to a new consciousness.
Here at Endoca, our mission is to prove that humanity
can survive without having to poison ourselves and the
world around us. The plants that we extract out CBD
hemp oils from are grown and cultivated organically
without herbicides or pesticides. Our extraction
methods are also clean and do not require the use
of chemicals or solvents. This allows us to attain an
exceptionally high level of purity in our hemp oils.
Your health and the health of the environment are our
first priorities.
We are currently developing our own packaging using
hemp fibers to reduce pollution caused by paper and
plastic production processes. The inks and dyes we
use will also be completely natural products.
Our next big step will be the use of hemp seed oil to
run our tractors and the use of solar energy as a
sustainable source of electricity for our facility. We
want to prove that 100% sustainable practices work,
and we want you to join us in our quest to make the
world a healthy place.
Mission
38. 38
Our vision includes the establishment of a village
surrounding our manufacturing site that’s 100%
sustainable and independent, a place where organic
food is grown and everything we need is produced in
the village. We’ll go further than just being ‘organic’ –
real permaculture principles will be implemented to
ensure maximum sustainability.
Raw Food Cannabis Hospital
In addition to being a home, we want to build a Raw
food hospital in our village, to be a place that people
visit and stay to learn more about and adopt healthier
lifestyle practices so that they can achieve healing
equilibrium and attain maximum wellness.
The reason we want to create a food hospital is that
we want to show people that you can often simply
eat your way to health. Eating organic raw food has
many health benefits. We also seek to use the profits
generated from the sales of our products to help
those in need, especially children.
We hope to build free accommodation and shelters for
the needy using hemp technologies, and even provide
them with work. We also hope to found an orphanage
where children will receive education and healthcare.
We have poured all profits from our sales into this
vision, and we have achieved excellent progress
towards its realization.
The Endoca Village