Plus CBD Oil - Hemp-Derived CBD: 10 Things You Need To Know
1. 10 Things You Need To Know
About Hemp-Derived CBD
Presented by: AimĂŠe Shunney, ND
2. 10 Things You Need To Know
About Hemp-Derived CBD
1.Semantics
2.History
3.Balance is
Everything
4.Utility
5.Grow Practices
6.Source
7.Whole Plant
Synergy
8.Research
9.Safety
10.Legal Questions
3. 1. Know Your Definitions
Cannabis Sativa,
Agricultural Hemp,
Medical Cannabis,
CBD & THC
4. Words Matter
â˘Cannabis Sativa L.
â Source of medical cannabis and agricultural hemp
â Contains 60-100 constituents
â THC: psychoactive
â CBD: not-psychotoxic
â˘Medical Cannabis (MC) - cannabis for medical
purposes
â Marijuana (MJ) - cannabis for recreational purposes
â˘Agricultural Hemp (AH) â until recently referred to the
commercial use of the cannabis stalk and seed
â less than 0.3% THC by dry weight
6. History of Cannabis
⢠First reported as medicine > 5000 years
⢠Introduced into Western medicine in
1840s by Dr. W.B. OâShaughnessy
⢠Cannabis extract from cannabis plants
was the medicine of choice in the early
1930s
⢠Promoted as analgesic, sedative, anti-
inflammatory, antispasmotic, and
anticonvulsant properties
⢠Available in 1906 Mfg by Eli Lilly, Wyeth
Park-Davis, Sharp & Dohme
8. Master Control System (ECS)
â˘Endocannabinoids are âmessengersâ, isolated from
brain and peripheral tissues that communicate via
cannabinoid receptors
âAnandamide and 2AG
âMain Receptors: CB1 and CB2
â˘Involved in the direct regulation of appetite, metabolic
health, pain/inflammation, thermoregulation, intra-
ocular pressure, sensation, muscle control,
motivation/reward, mood, and memory
â˘Involved in learning and synaptic plasticity
9. Balance is Everything
â˘ECS tone requires CB1 and CB2 balance as well as
âoptimalâ CB1 activation
â˘Optimal CB1 activity decreases anxiety, reduces pain,
decreases inflammation, controls sensory perception,
memory and cognitive function
â˘Anandamide binds to CB1 as does THC which can over
stimulate CB1
âStress will increase Anandamide
âAnandamide derived from Omega6
â˘Overstimulation of CB1 has many negative effects
10. WHY SHOULD WE CARE
ABOUT ECS TONE?
Source: http://eurheartjsupp.oxfordjournals.org/content/10/suppl_B/B34/F1.expansion
11. Master Control System (ECS)
ââŚScience has linked the ECS with
complex processes from anxiety to
immunityâŚThis research bonanza is
revealing more and more about the ECS
master control system and itâs shining
star, cannabidiol.â
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BEST CANNABIS PLAY AND A
RENEWED BUY AFTER Q4
RESULTS
READ THIS NEW
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âThe Medicinal Powers
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15. 5. Environmental and Health
Impact of Grow Practices
Agricultural Hemp vs
Medical Cannabis
16. Comparing Hemp to Medical Cannabis
Indoor Grown Medical Cannabis
⢠Enormous Carbon Foot Print
⢠Environmentally Harmful
⢠Wasteful Water Demands
⢠Huge Strain on Power Grid
⢠Consequences of Fungicides, Pesticides
and Fertilizers
⢠Unsustainable
Outdoor Grown Agricultural Hemp
⢠Sequesters CO2
⢠Environmentally Helpful
⢠Requires 80% less water
⢠Sun Powered Outdoor Grow
â No artificial light Sources required
⢠Zero Fungicides, Pesticides and Fertilizers
⢠Textbook Sustainability
20. NO! Source Does Not Matter
⢠CBD is CBD
⢠CBD from AH or high-CBD strain MC act
the same in our bodies
⢠CBD from AH affords a non-
psychoactive option
21. AndâŚAgricultural Hemp is Amazing!
⢠Non-psychotoxic
âSupports health and balance without a âhighâ
⢠Whole Plant Incredibly Useful
âFood, fiber, building materials, fuels â 25K uses!
⢠Nutrient-rich
â EFAs, amino acids, vitamin E, phosphorus, potassium,
sodium, magnesium, sulfur, calcium, iron, zinc
⢠Eco-friendly
â Sequesters CO2
â No herbicides
â Repletes soil
23. Whole Plant Synergy
â˘Entourage Effect â refers to the idea that different
constituents of cannabis work synergistically
âOverstates the importance of THC
âIgnores the benefits from all the other parts of the plant not
used when only ingesting flowers
â˘Hemptourage Effect â refers to the idea that you
get superior synergistic benefit from ingesting the
over 500 components found in the whole plant
âMinimal THC
27. Why Donât We Have More Research?
⢠Cannabis is listed as a Schedule 1 drug, making it
difficult to conduct research over certain limits
⢠CBD is not directly scheduled, there is no reference of CBD in
the Federal Acts
⢠AH not a controlled substance
⢠Only allowed to be grown under research oversight and
illegal to commercially grow and extract in US
⢠Good source material for phytocannabinoids is difficult
to obtain.
⢠Issues with growing, selling, and transporting across state
lines.
⢠Can be imported
29. CBDâs Remarkable Safety Profile
â˘Studies showing CBD as non-toxic
âDoes not induce changes on food intake, does not induce
catalepsy, does not affect physiological parameters (heart
rate, blood pressure and body temperature)
â Does not affect gastrointestinal transit nor alter psychomotor
or psychological functions.
â Chronic use and high doses up to 1,500 mg/day of CBD are
reportedly well tolerated in humans.
â˘Conclusion: Based on recent advances in cannabinoid
administration in humans, CBD shows safety in humans
and animals
31. Remember:
⢠Hemp is not defined as âmarijuanaâ under the Controlled
Substances Act (CSA)
⢠Expressly and intentionally excludes: mature stalks, fiber from stalks,
oil or cake made from seeds, any other compound, manufacture,
salt, derivative, mixture, or preparation of such mature stalks (except
resin extracted therefrom), fiber, oil, or cake, or the sterilized seed of
such plant which is incapable of germination.
⢠Naturally occurring cannabinoids in agricultural hemp foods,
including oils, were never scheduled under the CSA.
⢠Agricultural hemp fiber, stalk, seed, and oils can be lawfully
imported into the United States and these portions of the hemp
plant may enter into US commerce
32. In order to make the
highest quality CBD
products, we believe it
is imperative to be a
part of every step of
the supply chain
process.
FULL TRACEABILITY
FROM SEED TO SHELFâ˘
33. THE DIFFERENCE
BETWEEN OUR OILS
The raw oil is a total plant CO2 extract from agricultural hemp, imported from Europe. Cannabidiolic Acid, or
CBDA, comprises a significant proportion of the extracted cannabinoids in the raw oil. CBDA is an acidic
cannabinoid, the naturally-occurring raw form of CBD that is produced directly in the plant, and contains many
beneficial properties distinct from CBD.
RAW
DECARBOXYLATION
DISTILLED
TOTAL PLANT COMPLEX
GOLD FORMULA
Our Gold Formula is the ultimate step in refining our oil, where excess plant material is distilled from our
decarboxylated oil in a solvent-free process, rendering the oil gold in color. The final oil comprises only of CBD,
minor cannabinoids, and plant-derived fatty acids. Our Gold Formula oil is the highest-concentrated form of
CBD oil that we offer.
The raw oil undergoes a process called decarboxylation (a gentle heating process), in which most of the
remaining CBDA is converted into CBD to maximize the concentration of CBD.
For example, if the raw oil consisted of 100 milligrams of CBDA and 100 milligrams of CBD, the decarb oil will
contain a sum of 200 milligrams of CBD after decarboxylation, along with many of the cannabinoids, terpenes,
plant sterols, vitamin E and other natural plant material that comprises our Total Plant Complex.
40. Applicator use: Place 0.25mL on spoon.
Place in mouth and swallow. Adjust dose as
needed.
PlusCBD Oilâ˘
1g Green Applicator
Other Ingredients: none
41. Applicator use: Place 0.25mL on spoon.
Place in mouth and swallow. Adjust dose as
needed.
PlusCBD Oilâ˘
1g Gold Applicator
Other Ingredients: none
42. Applicator use: Place 0.25mL on spoon.
Place in mouth and swallow. Adjust dose as
needed.
PlusCBD Oilâ˘
3 & 10g Green Applicator
Other Ingredients: none
Other Ingredients: none
43. Applicator use: Place 0.25mL on spoon.
Place in mouth and swallow. Adjust dose as
needed.
PlusCBD Oilâ˘
3 & 10g Gold Applicators
Other Ingredients: none
Other Ingredients: none
45. PlusCBD Oilâ˘
1gm Grams
Other Ingredients:
None
SUGGESTED USE: Take 1 serving daily. Scoop 250 mg (1/4
container). Place in mouth and swallow.
TOTAL PLANT COMPLEXâ FOR THE PURIST
46. PlusCBD Oilâ˘
1gm Grams
Other Ingredients:
None
SUGGESTED USE: Take 1 serving daily. Scoop 250 mg (1/4
container). Place in mouth and swallow.
GOLD FORMULAâ FOR MAXIMUM EFFECT
47.
48. PROUD
MEMBERS OF:
American Herbal Products Association
Hemp Industries Association
Kentucky Hemp Industries Association
Kentucky Hemp Industry Council
European Industrial Hemp Association
National Hemp Association
49. Takeaways
What to Look For In a CBD
Company/Product?
âFull Traceability
âNo medical claims or dosing
recommendations
âEfforts to grow research
âGRAS self-determination/safety
assessments
âCommitment to Education
âInvolvement with Trade Organizations