The EMBL Australian Bioinformatics Resource (EMBL-ABR) is a distributed national research infrastructure that provides bioinformatics support to life science researchers in Australia. It has a hub-and-nodes structure with the hub hosted at the Victorian Life Science Computation Initiative at the University of Melbourne and 10 nodes located across Australian institutions. EMBL-ABR aims to increase Australia's capacity for bioinformatics research and data science, provide training in bioinformatics, and enable participation in international collaborations.