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Effects of Sympathetic Stimulation
.
1. ↑ Rate of rhythm of SA Node → ↑ Heart Rate
(Chronotropic Effect)
2. ↑ Excitability of AV Junctional fibers
(Bathmotropic Effect)
3. ↑ Conduction Velocity (Dromotropic Effect)
4. ↑ .Force of Contraction (Inotropic effect)
Effects of Parasympathetic Stimulation
1. ↓ Rate of rhythm of SA
Node↓ Heart Rate
2.↓ Excitability of AV Junctional
fibers→↓Conduction Velocity
3. ↓ Force of contraction
( By increasing membrane
permeability to K+ ions)
• Parasympathetic (vagal) nerves, which release
acetylcholine at their endings, innervate S-A
node andA-V junctional fibers proximal toA-V
node.
• Causes hyperpolarization because of increased
K+ permeability in response to acetylcholine.
• This causes decreased transmission of impulses
maybe temporarily stopping heart rate.
14
Parasympathetic Effects on Heart
Rate
2
Intrinsic Cardiac Conduction System
Approximately 1% of cardiac muscle cells are
autorhythmic rather than contractile
70-80/min
40-60/min
15-40/min
9
Regulation of the heart beat
• Sympathetic from the cardiac plexus supplies all parts of
the heart (atria, ventricle and all parts of the conduction
system)
• Parasympathetic from Vagus nerves supply mainly the
atria, SAandA
V nodes, very little supply to ventricles
• Sympathetic: increase the permeability of the cardiac cells
to Na+ and Ca++ i.e Positive Chronotropic and positive
Inotropic action
• Parasympathetic: Increase the permeability of the cardiac
cells to K+ and decrease its permeability to Na+ and Ca++
Extrinsic Innervation of the Heart

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Effects of Sympathetic Stimulation 1.pptx

  • 1. Effects of Sympathetic Stimulation . 1. ↑ Rate of rhythm of SA Node → ↑ Heart Rate (Chronotropic Effect) 2. ↑ Excitability of AV Junctional fibers (Bathmotropic Effect) 3. ↑ Conduction Velocity (Dromotropic Effect) 4. ↑ .Force of Contraction (Inotropic effect)
  • 2. Effects of Parasympathetic Stimulation 1. ↓ Rate of rhythm of SA Node↓ Heart Rate 2.↓ Excitability of AV Junctional fibers→↓Conduction Velocity 3. ↓ Force of contraction ( By increasing membrane permeability to K+ ions)
  • 3. • Parasympathetic (vagal) nerves, which release acetylcholine at their endings, innervate S-A node andA-V junctional fibers proximal toA-V node. • Causes hyperpolarization because of increased K+ permeability in response to acetylcholine. • This causes decreased transmission of impulses maybe temporarily stopping heart rate. 14 Parasympathetic Effects on Heart Rate
  • 4.
  • 5. 2 Intrinsic Cardiac Conduction System Approximately 1% of cardiac muscle cells are autorhythmic rather than contractile 70-80/min 40-60/min 15-40/min
  • 6.
  • 7.
  • 8.
  • 9. 9 Regulation of the heart beat • Sympathetic from the cardiac plexus supplies all parts of the heart (atria, ventricle and all parts of the conduction system) • Parasympathetic from Vagus nerves supply mainly the atria, SAandA V nodes, very little supply to ventricles • Sympathetic: increase the permeability of the cardiac cells to Na+ and Ca++ i.e Positive Chronotropic and positive Inotropic action • Parasympathetic: Increase the permeability of the cardiac cells to K+ and decrease its permeability to Na+ and Ca++