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Evidence-Based Medicine
in the Library
Rebecca Burbank
Nov. 22nd, 2013
Learning Objectives
• What is Evidence-Based Medicine
(EBM)?
• How can the Library support EBM
practitioners?
• What are a few helpful tools and
resources?
Evidence-Based Medicine
• Founded in statistics and systematic
review
• Focused on individual patients

Duke MCLA &UNC Health Sci Library
(2013). Introduction to evidencebased practice. Retrieved from
http://guides.mclibrary.duke.edu/eb
EBM is “the conscientious, explicit and
judicious use of current best evidence
in making decisions about the care of
the individual patient. It means
integrating individual clinical expertise
with the best available external clinical
evidence from systematic research.”
(Sackett, 1996)
Why do practitioners need EBM?
• Improved healthcare
• The need for proven practices in
medicine
• Standardization of practices
• Reduction of unnecessary care and
costs
Practicing EBM
•
•
•
•
•
•

Craft a clinical question
Search the medical literature
Identify the best study for the query
Critically appraise the study
Determine the clinical application
Evaluate your individual results

Mayer, D. (2004). Essential evidencebased medicine. Cambridge, UK:
Cambridge University Press.
Evidence Cycle
Assess

Ask

Apply

Patient
Acquire

Appraise
Duke MCLA &UNC Health Sci Library
How can we help you?
Librarians support EBM by teaching
users…
– To decode their clinical scenarios
• Define search query, identify alternate terms,
what is MeSH?

– Identification of appropriate sources
• Do I need a cohort study or an RCT?

– Appraisal of literature
• Look for bias in studies, determine validity
Problem Area
Formulating a
research question
PICO
Patient or Intervention or Comparison Outcomes
Problem Indicator
or Control
Tips for
Building

How would I
describe a
group of
patients like
mine?

Which main
intervention am I
considering?

What is the main What do I
alternative to
hope to
compare?
accomplish?
Patient specific
outcomes.

Balance
precision
with brevity.

Be specific.

Be Specific.

CEBM

Be specific.
Clinical Scenario
Mathew is a 16 year old who suffers with
major depressive disorder. He is currently
receiving cognitive-behavioral therapy
and wants to know if adding psychiatric
medication (like selective serotonin reuptake inhibitors or SSRIs) to his treatment,
will improve his treatment outcome.
Patient or
Adolescent SSRIs AND
Intervention
Problem
AND MDD
CBT

Comparison
CBT
or Control

Improve
Outcomes
treatment
Clinical Query
Would combining SSRIs and CBT improve
treatment in an adolescent with major
depressive disorder, when compared to CBT
alone?
Comparison
Patient or
Outcomes
Intervention or Control
Problem
Example

Adolescent
Depression
OR
Adolescent
“major
depressive
disorder”

SSRIs AND (CBT CBT OR
OR
psychotherapy
psychotherapy)

Reduced
depression
OR improved
treatment
Questions : Foreground vs.
Background

Background
questions
asked

Amount of expertise
Adolescent depression

SSRIs

Psychotherapy OR CBT

Improved treatment
Clinical Scenario
Ms. Baxter is a 60 year old woman with
osteoarthritis of the hip. Her daughter
has given her a magnetic bracelet to
relive the hip pain. Ms. Baxter is
skeptical and asks you, her physical
therapist, if there is any evidence to
support this.
Patient or
Adult
Problem
woman

Magnets OR
Intervention
Magnetic
or Indicator
bracelets

Comparison Reduced
N/A
Outcomes
or Control
pain

Duke MCLA &UNC Health Sci Library
Which is the Best Question?
A. Do magnets relive pain?
B. In women, do magnets reduce pain
from osteoarthritis of the hip?
C. In women, do magnetic bracelets
reduce pain from arthritis?
Clinical Scenario
Edith is a 85 year old woman who has
periods where she cannot remember
words or how to speak (aphasia). Her
husband asks her doctor if they should
be worried about Alzheimer's disease.
Patient
Woman or
Problem
elderly

Intervention
Aphasia
or Indicator

Comparison Alzheimer's
No aphasia Outcomes
or Control
OR
dementia
Clinical Query
What is the frequency of Alzheimer’s disease
amongst elderly women who are experiencing
aphasia?

Patient or Intervention
Problem or Indicator
Example

Comparison
or Control

Outcomes

Elderly
women

No aphasia

Alzheimer's
OR dementia

Aphasia OR
“memory lapse”
Recap
• EBM is the balance of patient’s
interests, clinical expertise, and best
available evidence
• The library can teach PICO to guide
the research process and create
clinical queries
• The Trip search engine can be used to
satisfy both background and
foreground questions
Thank You
Be sure to stop in for the next installment
EBM in the Library: Analyzing Statistical
Strength
This presentation can be found on slideshare!
@beckyburbank
References
•

CEBM (2009). Asking focused questions. Retrieved November 19,
2013 from http://www.cebm.net/?o=1036

•

Duke MCLA &UNC Health Sci Library (2013). Introduction to evidencebased practice. Retrieved November 19, 2013 from
http://guides.mclibrary.duke.edu/ebmtutorial

•

Mayer, D. (2004). Essential evidence-based medicine. Cambridge,
UK: Cambridge University Press.

•

Sackett, D. L., Rosenberg, W. M. C., Muir, G. J. A., & Brian, H. R. (1996).
Evidence based medicine: what it is and what it isn't. BMJ, 312(7023),
71.

•

Welty, E., Hofstetter, S., & Schulte, S. J. (2012). Time to re-evaluate
how we teach information literacy: Applying PICO in library
instruction. CRL News, 73(8), 476-477.

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EBM in the Library - PICO

  • 1. Evidence-Based Medicine in the Library Rebecca Burbank Nov. 22nd, 2013
  • 2. Learning Objectives • What is Evidence-Based Medicine (EBM)? • How can the Library support EBM practitioners? • What are a few helpful tools and resources?
  • 3. Evidence-Based Medicine • Founded in statistics and systematic review • Focused on individual patients Duke MCLA &UNC Health Sci Library (2013). Introduction to evidencebased practice. Retrieved from http://guides.mclibrary.duke.edu/eb
  • 4. EBM is “the conscientious, explicit and judicious use of current best evidence in making decisions about the care of the individual patient. It means integrating individual clinical expertise with the best available external clinical evidence from systematic research.” (Sackett, 1996)
  • 5. Why do practitioners need EBM? • Improved healthcare • The need for proven practices in medicine • Standardization of practices • Reduction of unnecessary care and costs
  • 6. Practicing EBM • • • • • • Craft a clinical question Search the medical literature Identify the best study for the query Critically appraise the study Determine the clinical application Evaluate your individual results Mayer, D. (2004). Essential evidencebased medicine. Cambridge, UK: Cambridge University Press.
  • 8. How can we help you? Librarians support EBM by teaching users… – To decode their clinical scenarios • Define search query, identify alternate terms, what is MeSH? – Identification of appropriate sources • Do I need a cohort study or an RCT? – Appraisal of literature • Look for bias in studies, determine validity
  • 10.
  • 11. PICO Patient or Intervention or Comparison Outcomes Problem Indicator or Control Tips for Building How would I describe a group of patients like mine? Which main intervention am I considering? What is the main What do I alternative to hope to compare? accomplish? Patient specific outcomes. Balance precision with brevity. Be specific. Be Specific. CEBM Be specific.
  • 12. Clinical Scenario Mathew is a 16 year old who suffers with major depressive disorder. He is currently receiving cognitive-behavioral therapy and wants to know if adding psychiatric medication (like selective serotonin reuptake inhibitors or SSRIs) to his treatment, will improve his treatment outcome. Patient or Adolescent SSRIs AND Intervention Problem AND MDD CBT Comparison CBT or Control Improve Outcomes treatment
  • 13. Clinical Query Would combining SSRIs and CBT improve treatment in an adolescent with major depressive disorder, when compared to CBT alone? Comparison Patient or Outcomes Intervention or Control Problem Example Adolescent Depression OR Adolescent “major depressive disorder” SSRIs AND (CBT CBT OR OR psychotherapy psychotherapy) Reduced depression OR improved treatment
  • 14. Questions : Foreground vs. Background Background questions asked Amount of expertise
  • 15.
  • 17.
  • 18.
  • 19.
  • 20. Clinical Scenario Ms. Baxter is a 60 year old woman with osteoarthritis of the hip. Her daughter has given her a magnetic bracelet to relive the hip pain. Ms. Baxter is skeptical and asks you, her physical therapist, if there is any evidence to support this. Patient or Adult Problem woman Magnets OR Intervention Magnetic or Indicator bracelets Comparison Reduced N/A Outcomes or Control pain Duke MCLA &UNC Health Sci Library
  • 21. Which is the Best Question? A. Do magnets relive pain? B. In women, do magnets reduce pain from osteoarthritis of the hip? C. In women, do magnetic bracelets reduce pain from arthritis?
  • 22. Clinical Scenario Edith is a 85 year old woman who has periods where she cannot remember words or how to speak (aphasia). Her husband asks her doctor if they should be worried about Alzheimer's disease. Patient Woman or Problem elderly Intervention Aphasia or Indicator Comparison Alzheimer's No aphasia Outcomes or Control OR dementia
  • 23. Clinical Query What is the frequency of Alzheimer’s disease amongst elderly women who are experiencing aphasia? Patient or Intervention Problem or Indicator Example Comparison or Control Outcomes Elderly women No aphasia Alzheimer's OR dementia Aphasia OR “memory lapse”
  • 24. Recap • EBM is the balance of patient’s interests, clinical expertise, and best available evidence • The library can teach PICO to guide the research process and create clinical queries • The Trip search engine can be used to satisfy both background and foreground questions
  • 25. Thank You Be sure to stop in for the next installment EBM in the Library: Analyzing Statistical Strength This presentation can be found on slideshare! @beckyburbank
  • 26. References • CEBM (2009). Asking focused questions. Retrieved November 19, 2013 from http://www.cebm.net/?o=1036 • Duke MCLA &UNC Health Sci Library (2013). Introduction to evidencebased practice. Retrieved November 19, 2013 from http://guides.mclibrary.duke.edu/ebmtutorial • Mayer, D. (2004). Essential evidence-based medicine. Cambridge, UK: Cambridge University Press. • Sackett, D. L., Rosenberg, W. M. C., Muir, G. J. A., & Brian, H. R. (1996). Evidence based medicine: what it is and what it isn't. BMJ, 312(7023), 71. • Welty, E., Hofstetter, S., & Schulte, S. J. (2012). Time to re-evaluate how we teach information literacy: Applying PICO in library instruction. CRL News, 73(8), 476-477.