The document summarizes the anatomy and physiology of the ear. It is divided into three main parts: the external ear, middle ear, and inner ear. The external ear collects sound waves and directs them through the external auditory canal to the tympanic membrane. The middle ear contains three small bones (ossicles) that transmit sound vibrations from the tympanic membrane to the inner ear. The inner ear, or labyrinth, contains the cochlea for hearing and semicircular canals for balance. It converts sound vibrations into neural signals that are sent to the brain.
Anatomy of ear by dr. bomkar bam (MS) entBomkar Bam
The document summarizes the anatomy of the ear in 3 parts:
1) The external ear including the auricle, external auditory canal, and tympanic membrane.
2) The middle ear including the tympanic cavity bounded by six walls and containing the ossicles.
3) The inner ear which is not described in detail.
The summary provides a high-level overview of the key structures and organization of the ear in 3 sentences.
The document describes the anatomy of the nose, including its external structures, internal nasal cavity, blood supply, nerve supply, and lymphatic drainage. It details the bones and cartilages that make up the external nose and nasal septum, and describes the nasal vestibule, nasal cavities, nasal conchae and meatuses within the nasal cavity. It also outlines the skin lining, blood vessels, nerves and lymphatic drainage of the nose.
The nasopharynx lies behind the nasal cavity and above the soft palate. It is bounded anteriorly by the choanae and posterior nasal septum, inferiorly by the soft palate, and posterosuperiorly by the skull base. The nasopharynx contains lymphoid tissue and its epithelium changes from ciliated to squamous with age. Juvenile angiofibromas are vascular tumors that typically present in adolescent males with nasal obstruction and bleeding. Nasopharyngeal carcinoma is strongly associated with Epstein-Barr virus and presents with neck masses, cranial neuropathies, and distant metastases. Staging guides prognosis and treatment, which typically involves radiation therapy with surgery
Cross Sectional Anatomy of Paranasal sinus Sarbesh Tiwari
The document summarizes the anatomy and variations of the paranasal sinuses. It describes the locations and openings of the different sinus groups. Key anatomical structures involved in sinus drainage like the osteomeatal complex are also explained. Common anatomic variations seen on imaging that can affect sinus drainage are discussed. These variations include concha bullosa, Haller cells, Onodi cells and pneumatization of surrounding bones.
The document discusses the basic structure and components of the brain stem. It describes the three main portions as the roof plate, tegmentum, and basal portion. It then provides detailed information on the descending tracts in the basal portion, including the corticospinal, corticobulbar, and corticopontocerebellar fibers. It also discusses the various cranial nerve nuclei, precerebellar nuclei, and ascending sensory pathways located within the brain stem that are involved in motor and sensory functions.
This document provides guidelines for performing and interpreting a normal chest x-ray. It describes recommended projections including PA, AP, lateral, and oblique views. Proper positioning, centering, penetration, and rotation are discussed. Key anatomical structures are defined, such as the mediastinum, heart, lungs, fissures, hila, and diaphragm. Common variations and pathological findings are outlined. The document aims to serve as a reference for radiologists in evaluating and diagnosing chest x-ray images.
This document provides an overview of endoscopic nasal anatomy. It begins with a brief introduction to endoscopy and its historical evolution. It then describes the external nose, nasal septum, lateral nasal wall including the inferior, middle, and superior turbinates. Various anatomical variations are also discussed. The paranasal sinuses, anterior skull base, and endoscopic approaches to different nasal and sinus structures like the frontal sinus and sphenoid sinus are summarized. Key landmarks and variations are highlighted to provide a concise yet comprehensive summary of the essential endoscopic nasal anatomy concepts covered in the document.
1) Tumors of the hypopharynx most commonly occur in the pyriform sinus, postcricoid region, and posterior pharyngeal wall.
2) Risk factors for hypopharyngeal tumors include smoking, alcohol use, poor nutrition, and human papillomavirus. Genetic factors and occupational exposures also contribute to cancer risk.
3) Diagnosis involves laryngoscopy, barium swallow, CT scan, and biopsy. Treatment depends on the size and extent of the tumor, and may involve radiation, surgery such as laryngectomy or pharyngectomy, or a combination of the two.
Anatomy of ear by dr. bomkar bam (MS) entBomkar Bam
The document summarizes the anatomy of the ear in 3 parts:
1) The external ear including the auricle, external auditory canal, and tympanic membrane.
2) The middle ear including the tympanic cavity bounded by six walls and containing the ossicles.
3) The inner ear which is not described in detail.
The summary provides a high-level overview of the key structures and organization of the ear in 3 sentences.
The document describes the anatomy of the nose, including its external structures, internal nasal cavity, blood supply, nerve supply, and lymphatic drainage. It details the bones and cartilages that make up the external nose and nasal septum, and describes the nasal vestibule, nasal cavities, nasal conchae and meatuses within the nasal cavity. It also outlines the skin lining, blood vessels, nerves and lymphatic drainage of the nose.
The nasopharynx lies behind the nasal cavity and above the soft palate. It is bounded anteriorly by the choanae and posterior nasal septum, inferiorly by the soft palate, and posterosuperiorly by the skull base. The nasopharynx contains lymphoid tissue and its epithelium changes from ciliated to squamous with age. Juvenile angiofibromas are vascular tumors that typically present in adolescent males with nasal obstruction and bleeding. Nasopharyngeal carcinoma is strongly associated with Epstein-Barr virus and presents with neck masses, cranial neuropathies, and distant metastases. Staging guides prognosis and treatment, which typically involves radiation therapy with surgery
Cross Sectional Anatomy of Paranasal sinus Sarbesh Tiwari
The document summarizes the anatomy and variations of the paranasal sinuses. It describes the locations and openings of the different sinus groups. Key anatomical structures involved in sinus drainage like the osteomeatal complex are also explained. Common anatomic variations seen on imaging that can affect sinus drainage are discussed. These variations include concha bullosa, Haller cells, Onodi cells and pneumatization of surrounding bones.
The document discusses the basic structure and components of the brain stem. It describes the three main portions as the roof plate, tegmentum, and basal portion. It then provides detailed information on the descending tracts in the basal portion, including the corticospinal, corticobulbar, and corticopontocerebellar fibers. It also discusses the various cranial nerve nuclei, precerebellar nuclei, and ascending sensory pathways located within the brain stem that are involved in motor and sensory functions.
This document provides guidelines for performing and interpreting a normal chest x-ray. It describes recommended projections including PA, AP, lateral, and oblique views. Proper positioning, centering, penetration, and rotation are discussed. Key anatomical structures are defined, such as the mediastinum, heart, lungs, fissures, hila, and diaphragm. Common variations and pathological findings are outlined. The document aims to serve as a reference for radiologists in evaluating and diagnosing chest x-ray images.
This document provides an overview of endoscopic nasal anatomy. It begins with a brief introduction to endoscopy and its historical evolution. It then describes the external nose, nasal septum, lateral nasal wall including the inferior, middle, and superior turbinates. Various anatomical variations are also discussed. The paranasal sinuses, anterior skull base, and endoscopic approaches to different nasal and sinus structures like the frontal sinus and sphenoid sinus are summarized. Key landmarks and variations are highlighted to provide a concise yet comprehensive summary of the essential endoscopic nasal anatomy concepts covered in the document.
1) Tumors of the hypopharynx most commonly occur in the pyriform sinus, postcricoid region, and posterior pharyngeal wall.
2) Risk factors for hypopharyngeal tumors include smoking, alcohol use, poor nutrition, and human papillomavirus. Genetic factors and occupational exposures also contribute to cancer risk.
3) Diagnosis involves laryngoscopy, barium swallow, CT scan, and biopsy. Treatment depends on the size and extent of the tumor, and may involve radiation, surgery such as laryngectomy or pharyngectomy, or a combination of the two.
This document discusses drug-induced vertigo (ototoxicity) caused by certain medications damaging the inner ear. The most common ototoxic drugs are aminoglycosides, loop diuretics, anti-neoplastic agents, quinine, and salicylates. Aminoglycosides like streptomycin can cause permanent hearing loss and vestibular toxicity by generating reactive oxygen species and activating caspases in hair cells. Loop diuretics may cause temporary hearing loss through changes in ionic gradients in the inner ear. Anti-neoplastic agents such as cisplatin commonly cause irreversible, progressive hearing loss through free radical production and apoptotic cell death. Risk of ototoxicity from these drugs can
Presentation1.pptx, radiological anatomy of the neck.Abdellah Nazeer
This document provides an overview of the radiological anatomy of the neck. It describes the superficial and deep neck structures, including the seven compartments of the deep neck. It details the various spaces in the suprahyoid and infrahyoid regions of the neck. Images and diagrams show neck anatomy on different MRI sequences at multiple levels. Specific structures like the brachial plexus, larynx, lymph nodes, and vasculature are called out. The document serves as a reference for radiologists to understand neck anatomy on radiological exams.
Anatomy of lungs 3DR NIKUNJ R SHEKHADA (MBBS,MS GEN SURG DNB CTS SR)DR NIKUNJ SHEKHADA
The document provides an overview of lung anatomy including:
- The right lung has three lobes and the left has two lobes, separated by fissures.
- Each lobe is further divided into bronchopulmonary segments supplied by segmental bronchi and arteries that parallel the airways.
- The trachea bifurcates into right and left mainstem bronchi which branch into lobar, segmental and subsegmental branches.
- Pulmonary veins mirror the arterial system, draining into segmental veins and lobar veins that coalesce into the left and right pulmonary veins.
- The bronchial arteries arise systemically to supply the conducting airways.
1. Pre-operative imaging such as HRCT and MRI are important for cochlear implantation to evaluate anatomical variations and identify any contraindications.
2. Key factors assessed on imaging include the size of the internal auditory meatus, status of the cochlear nerve, and presence of any neurovascular anomalies which could increase surgical risk.
3. Congenital anomalies of the bony labyrinth or membranous structures detected on pre-operative imaging may influence the surgical approach and expectations of device insertion and outcome.
The nose has several important functions: respiration, protection of the lower respiratory tract, vocal resonance, olfaction, drainage of secretions, and maintaining eustachian tube function. It filters and conditions air through mechanisms like mucociliary clearance and the nasal cycle. Secretions produced in the nose help fight infections and allergens with lysozymes, immunoglobulins, and interferons. The olfactory epithelium allows for smell detection which is important for functions like regulating food intake and detecting toxins.
The document discusses radiology of the nose and paranasal sinuses. It describes the anatomy of the four paranasal sinus groups and details their development. It provides imaging techniques for visualizing the sinuses including lateral, Caldwell's view, Waters' view, submentovertex view. CT scanning is described as the gold standard for providing detailed bony anatomy and assessing sinus pathology or planning surgery. Key anatomical structures seen on coronal and axial CT cuts are outlined.
Endoscopic anatomy of nose ,paranasal sinus and anterior skull baseRajat Jain
This document provides an overview of nasal endoscopic anatomy and the endoscopic examination technique. It describes the three passes used in endoscopy to examine the different anatomical structures of the nose and paranasal sinuses. The first pass examines the nasal septum, inferior turbinate, and posterior choana. The second pass examines the superior turbinate, sphenoethmoidal recess, and sphenoid ostium. The third pass examines the middle meatus, uncinate process, bulla ethmoidalis, and maxillary ostium. It also describes important anatomical structures like the turbinates, sinuses, arteries and variations that can be observed during nasal endoscopy.
1. The inner ear consists of the bony labyrinth within the temporal bone and the membranous labyrinth contained within.
2. The bony labyrinth is composed of the vestibule, semicircular canals, and cochlea. The membranous labyrinth contains the cochlear duct, utricle, saccule, and semicircular ducts filled with endolymph.
3. Within the cochlea, the organ of Corti transduces sound into electrical signals via inner and outer hair cells. The hair cells sit on the basilar membrane and are stimulated by the overlying tectorial membrane.
Congenital Malformations of Inner Ear.pptxDHWANIMEHTA49
This is a presentation on the Congenital Malformations of the Inner Ear. This PPT contains a brief embryology to understand the abnormalities of the different parts of inner ear during the development. The Classification of malformations is given which has been taken from a renowned reference book. For better understanding flowcharts and figures are included. Supportive radiological images for every malformation has been included for clinical knowledge and better understanding of the malformations.
This document discusses the anatomy seen on CT scans of the temporal bone in different planes. It provides details on key structures visible in the axial, coronal, and sagittal planes, including the semicircular canals, cochlea, facial nerve canal, ossicles, and mastoid air cells. Different anatomical compartments of the middle ear are also described based on coronal imaging. The purpose is to identify relevant anatomy, assess disease extension and surgical planning for ear procedures.
The document provides information on the anatomy of the ear and auditory pathway. It discusses the three parts of the ear - external ear, middle ear, and inner ear. The external ear includes the pinna and external auditory meatus. The middle ear contains the tympanic membrane, three ossicles (malleus, incus, stapes), and two small muscles (tensor tympani and stapedius). The inner ear is made up of the cochlea and vestibular system. The auditory pathway transmits signals from the inner ear to the brainstem and auditory cortex.
This document provides an overview of temporal bone anatomy and imaging as well as common temporal bone pathologies. It begins with a detailed description of the embryology, anatomy, and imaging appearance of the various structures of the temporal bone. This is followed by sections on common temporal bone traumas including fractures, ossicular injuries, and complications such as fistulas and facial nerve dysfunction. Imaging techniques for evaluation of the temporal bone including multi-planar CT are also discussed.
The hypoglossal nerve is a purely motor nerve that originates in the medulla and innervates the muscles of the tongue. It emerges from the medulla between the pyramid and inferior olive, descends through the neck, and divides to supply branches to the extrinsic and intrinsic tongue muscles. Examination of the tongue evaluates strength, bulk, and dexterity to identify weaknesses or atrophies that may indicate supranuclear, nuclear, or infranuclear lesions along the nerve's path.
The middle ear cavity is located between the tympanic membrane and inner ear. It contains the auditory ossicles (malleus, incus, stapes), muscles (tensor tympani, stapedius), and is connected to the nasopharynx via the Eustachian tube. The cavity has thin bony walls that separate it from important structures like the cranial fossa and carotid artery. The ossicles transmit sound vibrations from the tympanic membrane to the inner ear.
Presentation1.pptx, radiological anatomy of the brain and pituitary glandAbdellah Nazeer
The document summarizes the normal radiological anatomy of the brain and pituitary gland as seen on computed tomography (CT) and magnetic resonance imaging (MRI). It describes the overall structure of the brain, including the cerebrum, cerebellum, brainstem, and four ventricles. It details the anatomy of the lateral, third, and fourth ventricles. It then outlines the major lobes and gyri of the cerebral hemispheres, including important motor and sensory areas. The document concludes by reviewing sectional anatomy as seen on axial CT and MRI scans.
The vestibular apparatus contains the semicircular canals, utricle, and saccule which help detect head movement and orientation. The hair cells in these structures bend in response to movement, triggering nerve impulses about head position. This information is integrated in the brain to maintain balance and stabilize gaze. Dysfunctions can cause vertigo and imbalance from issues like BPPV or strokes affecting the vestibular system.
this prsentation incluses HRCT temportal bone cross sectional anatomy images axial saggital and coronal with labelled diagram. This presentation help alot for radiology resident. Thanks.
This document discusses the anatomy and parts of the ear, including the external ear, middle ear, and inner ear. It describes the structures within the middle ear cleft such as the three ossicles, two muscles, chorda tympani, and tympanic plexus. It also outlines the layers of the tympanic membrane and its nerve supply. Finally, it provides details on the inner ear and functions of the mastoid air cells and fluid compartments.
- Balloon sinuplasty is a minimally invasive technique for treating sinusitis using balloon catheters to dilate sinus ostia rather than conventional endoscopic sinus surgery.
- Studies show balloon sinuplasty improves symptoms in selected patients with chronic sinusitis and is safe, with minimal adverse effects. However, longer term data is still needed to define its optimal role and indications.
- While initial data is promising for symptom relief and preservation of sinus anatomy compared to traditional FESS, balloon sinuplasty may not eliminate the need for conventional sinus surgery in all patients.
The document provides an overview of the anatomy of the ear, which is divided into three main parts:
1. The external ear includes the pinna, external auditory canal, and tympanic membrane.
2. The middle ear contains the ossicles (malleus, incus, stapes), muscles, lining, and connections to structures like the Eustachian tube and mastoid air cells.
3. The internal ear, or labyrinth, houses the bony and membranous structures involved in balance and hearing, including the vestibule, semicircular canals, and cochlea.
This document discusses drug-induced vertigo (ototoxicity) caused by certain medications damaging the inner ear. The most common ototoxic drugs are aminoglycosides, loop diuretics, anti-neoplastic agents, quinine, and salicylates. Aminoglycosides like streptomycin can cause permanent hearing loss and vestibular toxicity by generating reactive oxygen species and activating caspases in hair cells. Loop diuretics may cause temporary hearing loss through changes in ionic gradients in the inner ear. Anti-neoplastic agents such as cisplatin commonly cause irreversible, progressive hearing loss through free radical production and apoptotic cell death. Risk of ototoxicity from these drugs can
Presentation1.pptx, radiological anatomy of the neck.Abdellah Nazeer
This document provides an overview of the radiological anatomy of the neck. It describes the superficial and deep neck structures, including the seven compartments of the deep neck. It details the various spaces in the suprahyoid and infrahyoid regions of the neck. Images and diagrams show neck anatomy on different MRI sequences at multiple levels. Specific structures like the brachial plexus, larynx, lymph nodes, and vasculature are called out. The document serves as a reference for radiologists to understand neck anatomy on radiological exams.
Anatomy of lungs 3DR NIKUNJ R SHEKHADA (MBBS,MS GEN SURG DNB CTS SR)DR NIKUNJ SHEKHADA
The document provides an overview of lung anatomy including:
- The right lung has three lobes and the left has two lobes, separated by fissures.
- Each lobe is further divided into bronchopulmonary segments supplied by segmental bronchi and arteries that parallel the airways.
- The trachea bifurcates into right and left mainstem bronchi which branch into lobar, segmental and subsegmental branches.
- Pulmonary veins mirror the arterial system, draining into segmental veins and lobar veins that coalesce into the left and right pulmonary veins.
- The bronchial arteries arise systemically to supply the conducting airways.
1. Pre-operative imaging such as HRCT and MRI are important for cochlear implantation to evaluate anatomical variations and identify any contraindications.
2. Key factors assessed on imaging include the size of the internal auditory meatus, status of the cochlear nerve, and presence of any neurovascular anomalies which could increase surgical risk.
3. Congenital anomalies of the bony labyrinth or membranous structures detected on pre-operative imaging may influence the surgical approach and expectations of device insertion and outcome.
The nose has several important functions: respiration, protection of the lower respiratory tract, vocal resonance, olfaction, drainage of secretions, and maintaining eustachian tube function. It filters and conditions air through mechanisms like mucociliary clearance and the nasal cycle. Secretions produced in the nose help fight infections and allergens with lysozymes, immunoglobulins, and interferons. The olfactory epithelium allows for smell detection which is important for functions like regulating food intake and detecting toxins.
The document discusses radiology of the nose and paranasal sinuses. It describes the anatomy of the four paranasal sinus groups and details their development. It provides imaging techniques for visualizing the sinuses including lateral, Caldwell's view, Waters' view, submentovertex view. CT scanning is described as the gold standard for providing detailed bony anatomy and assessing sinus pathology or planning surgery. Key anatomical structures seen on coronal and axial CT cuts are outlined.
Endoscopic anatomy of nose ,paranasal sinus and anterior skull baseRajat Jain
This document provides an overview of nasal endoscopic anatomy and the endoscopic examination technique. It describes the three passes used in endoscopy to examine the different anatomical structures of the nose and paranasal sinuses. The first pass examines the nasal septum, inferior turbinate, and posterior choana. The second pass examines the superior turbinate, sphenoethmoidal recess, and sphenoid ostium. The third pass examines the middle meatus, uncinate process, bulla ethmoidalis, and maxillary ostium. It also describes important anatomical structures like the turbinates, sinuses, arteries and variations that can be observed during nasal endoscopy.
1. The inner ear consists of the bony labyrinth within the temporal bone and the membranous labyrinth contained within.
2. The bony labyrinth is composed of the vestibule, semicircular canals, and cochlea. The membranous labyrinth contains the cochlear duct, utricle, saccule, and semicircular ducts filled with endolymph.
3. Within the cochlea, the organ of Corti transduces sound into electrical signals via inner and outer hair cells. The hair cells sit on the basilar membrane and are stimulated by the overlying tectorial membrane.
Congenital Malformations of Inner Ear.pptxDHWANIMEHTA49
This is a presentation on the Congenital Malformations of the Inner Ear. This PPT contains a brief embryology to understand the abnormalities of the different parts of inner ear during the development. The Classification of malformations is given which has been taken from a renowned reference book. For better understanding flowcharts and figures are included. Supportive radiological images for every malformation has been included for clinical knowledge and better understanding of the malformations.
This document discusses the anatomy seen on CT scans of the temporal bone in different planes. It provides details on key structures visible in the axial, coronal, and sagittal planes, including the semicircular canals, cochlea, facial nerve canal, ossicles, and mastoid air cells. Different anatomical compartments of the middle ear are also described based on coronal imaging. The purpose is to identify relevant anatomy, assess disease extension and surgical planning for ear procedures.
The document provides information on the anatomy of the ear and auditory pathway. It discusses the three parts of the ear - external ear, middle ear, and inner ear. The external ear includes the pinna and external auditory meatus. The middle ear contains the tympanic membrane, three ossicles (malleus, incus, stapes), and two small muscles (tensor tympani and stapedius). The inner ear is made up of the cochlea and vestibular system. The auditory pathway transmits signals from the inner ear to the brainstem and auditory cortex.
This document provides an overview of temporal bone anatomy and imaging as well as common temporal bone pathologies. It begins with a detailed description of the embryology, anatomy, and imaging appearance of the various structures of the temporal bone. This is followed by sections on common temporal bone traumas including fractures, ossicular injuries, and complications such as fistulas and facial nerve dysfunction. Imaging techniques for evaluation of the temporal bone including multi-planar CT are also discussed.
The hypoglossal nerve is a purely motor nerve that originates in the medulla and innervates the muscles of the tongue. It emerges from the medulla between the pyramid and inferior olive, descends through the neck, and divides to supply branches to the extrinsic and intrinsic tongue muscles. Examination of the tongue evaluates strength, bulk, and dexterity to identify weaknesses or atrophies that may indicate supranuclear, nuclear, or infranuclear lesions along the nerve's path.
The middle ear cavity is located between the tympanic membrane and inner ear. It contains the auditory ossicles (malleus, incus, stapes), muscles (tensor tympani, stapedius), and is connected to the nasopharynx via the Eustachian tube. The cavity has thin bony walls that separate it from important structures like the cranial fossa and carotid artery. The ossicles transmit sound vibrations from the tympanic membrane to the inner ear.
Presentation1.pptx, radiological anatomy of the brain and pituitary glandAbdellah Nazeer
The document summarizes the normal radiological anatomy of the brain and pituitary gland as seen on computed tomography (CT) and magnetic resonance imaging (MRI). It describes the overall structure of the brain, including the cerebrum, cerebellum, brainstem, and four ventricles. It details the anatomy of the lateral, third, and fourth ventricles. It then outlines the major lobes and gyri of the cerebral hemispheres, including important motor and sensory areas. The document concludes by reviewing sectional anatomy as seen on axial CT and MRI scans.
The vestibular apparatus contains the semicircular canals, utricle, and saccule which help detect head movement and orientation. The hair cells in these structures bend in response to movement, triggering nerve impulses about head position. This information is integrated in the brain to maintain balance and stabilize gaze. Dysfunctions can cause vertigo and imbalance from issues like BPPV or strokes affecting the vestibular system.
this prsentation incluses HRCT temportal bone cross sectional anatomy images axial saggital and coronal with labelled diagram. This presentation help alot for radiology resident. Thanks.
This document discusses the anatomy and parts of the ear, including the external ear, middle ear, and inner ear. It describes the structures within the middle ear cleft such as the three ossicles, two muscles, chorda tympani, and tympanic plexus. It also outlines the layers of the tympanic membrane and its nerve supply. Finally, it provides details on the inner ear and functions of the mastoid air cells and fluid compartments.
- Balloon sinuplasty is a minimally invasive technique for treating sinusitis using balloon catheters to dilate sinus ostia rather than conventional endoscopic sinus surgery.
- Studies show balloon sinuplasty improves symptoms in selected patients with chronic sinusitis and is safe, with minimal adverse effects. However, longer term data is still needed to define its optimal role and indications.
- While initial data is promising for symptom relief and preservation of sinus anatomy compared to traditional FESS, balloon sinuplasty may not eliminate the need for conventional sinus surgery in all patients.
The document provides an overview of the anatomy of the ear, which is divided into three main parts:
1. The external ear includes the pinna, external auditory canal, and tympanic membrane.
2. The middle ear contains the ossicles (malleus, incus, stapes), muscles, lining, and connections to structures like the Eustachian tube and mastoid air cells.
3. The internal ear, or labyrinth, houses the bony and membranous structures involved in balance and hearing, including the vestibule, semicircular canals, and cochlea.
The middle ear cleft consists of the tympanic cavity, Eustachian tube, and mastoid air cell system. The tympanic cavity is divided into three compartments - the epitympanum, mesotympanum, and hypotympanum. It contains the three ossicles (malleus, incus, stapes), two muscles (tensor tympani and stapedius), and two nerves (chorda tympani and tympanic plexus). The tympanic cavity has six boundaries - the roof, floor, medial, lateral, anterior, and posterior walls. The ossicles transmit sound from the tympanic membrane to the oval window of the inner ear
The ear is divided into three parts - external, middle, and inner ear. The external ear includes the auricle and external auditory canal. The middle ear, or tympanic cavity, contains the three ossicles (malleus, incus, stapes) and two small muscles (tensor tympani and stapedius). It is separated from the inner ear by the oval and round windows. The complex anatomy of the middle ear, including its walls, spaces, folds, and vascular and neural supply, allow it to efficiently transmit sound vibrations from the outer to inner ear.
The document summarizes key anatomical structures and features of the middle ear. It describes how the middle ear extends beyond the tympanic membrane and can be divided into three regions. It identifies important bones, openings, and nerves that make up the walls and boundaries of the middle ear space. These include the tegmen tympani bone, jugular bulb, ossicles (malleus, incus, stapes), oval window, round window, and facial nerve canal. Blood supply and lymphatic drainage of the middle ear are also outlined.
Provides a detailed description of the gross anatomy of the ear for undergraduate medical students; i.e. parts of the ear, structures found, their blood supply, their innervation, developmental origins & their functions. It also includes examples of common disorders associated with those parts.
The ear is divided into three parts - external, middle, and internal. The external ear consists of the pinna and external auditory meatus. The pinna has elevations like the helix and depressions like the concha. The middle ear contains the auditory ossicles and transmits sound from the tympanic membrane to the inner ear. The internal ear contains the membranous labyrinth within the bony labyrinth, and is responsible for hearing and balance. It includes the cochlea, saccule, utricle and semicircular canals.
The document provides an overview of the anatomy and physiology of the ear and nose. It describes the three parts of the ear - external, middle, and inner - and details the structures within each part such as the pinna, external auditory meatus, eardrum, ossicles, and cochlea. It also describes the anatomy of the nose, including the nasal cavity, septum, turbinates, and paranasal sinuses. Key functions such as olfaction, filtration, humidification are also summarized.
The document provides an overview of the anatomy and physiology of the ear, nose, pharynx, and larynx. It describes the external, middle, and inner parts of the ear. It outlines the structures in the nose including the nasal cavity, septum, turbinates, and paranasal sinuses. It details the three parts of the pharynx and lymphoid tissues. It concludes with the cartilage, spaces, folds and cords that make up the larynx.
The middle ear is a six-walled air-filled cavity located in the petrous part of the temporal bone between the inner and outer ear. It has three divisions - the epitympanum above the eardrum, the mesotympanum opposite the eardrum, and the hypotympanum below the eardrum. The middle ear contains the three ossicles (malleus, incus, stapes) that transmit sound vibrations from the eardrum to the inner ear. It is lined by epithelium and contains the tensor tympani and stapedius muscles that help dampen loud sounds. Blood supply comes from branches of the maxillary and posterior auricular arteries.
The document provides an overview of the anatomy of the ear and mastoid. It is divided into three main sections: external ear, middle ear, and inner ear. The external ear includes the pinna and external auditory canal. The middle ear contains the three ossicles, two muscles, and two nerves. It is divided into four regions. The inner ear includes the bony and membranous labyrinths, which contain the cochlea, vestibule, and semicircular canals. The organ of Corti, located in the cochlea, is the sensory organ for hearing.
The document summarizes the structure and function of the human ear. It describes the ear as having three main parts: the outer, middle, and inner ear. The outer ear collects sound waves and directs them through the auditory canal to the middle ear, where the vibrations are transmitted through three small bones to the inner ear. In the inner ear, fluid waves stimulate hair cells to generate nerve impulses that travel to the brain for hearing and balance. The ear detects sound properties like pitch from frequency and volume from amplitude to enable hearing perception.
The document summarizes the anatomy of the middle ear, including its walls, contents, ossicles, muscles, nerves, and mucosa. Key points include:
1) The anterior, posterior, medial, lateral, floor and roof walls contain important structures like openings for nerves and muscles.
2) The middle ear contains the ossicles (malleus, incus, stapes), tensor tympani and stapedius muscles, tympanic plexus and chorda tympani nerve.
3) The ossicles transmit sound from the tympanic membrane to the oval window. The muscles protect the inner ear from loud noises.
The document summarizes the anatomy of the middle ear. It describes the structures found within the middle ear cavity including the ossicles (malleus, incus, stapes), muscles (tensor tympani, stapedius), nerves (facial, glossopharyngeal) and blood supply. It also details the six walls that make up the middle ear cavity - roof, floor, medial, lateral, anterior and posterior walls - and their anatomical features and relationships.
Promoting Wellbeing - Applied Social Psychology - Psychology SuperNotesPsychoTech Services
A proprietary approach developed by bringing together the best of learning theories from Psychology, design principles from the world of visualization, and pedagogical methods from over a decade of training experience, that enables you to: Learn better, faster!
These lecture slides, by Dr Sidra Arshad, offer a simplified look into the mechanisms involved in the regulation of respiration:
Learning objectives:
1. Describe the organisation of respiratory center
2. Describe the nervous control of inspiration and respiratory rhythm
3. Describe the functions of the dorsal and respiratory groups of neurons
4. Describe the influences of the Pneumotaxic and Apneustic centers
5. Explain the role of Hering-Breur inflation reflex in regulation of inspiration
6. Explain the role of central chemoreceptors in regulation of respiration
7. Explain the role of peripheral chemoreceptors in regulation of respiration
8. Explain the regulation of respiration during exercise
9. Integrate the respiratory regulatory mechanisms
10. Describe the Cheyne-Stokes breathing
Study Resources:
1. Chapter 42, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 36, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 13, Human Physiology by Lauralee Sherwood, 9th edition
DECLARATION OF HELSINKI - History and principlesanaghabharat01
This SlideShare presentation provides a comprehensive overview of the Declaration of Helsinki, a foundational document outlining ethical guidelines for conducting medical research involving human subjects.
Lecture 6 -- Memory 2015.pptlearning occurs when a stimulus (unconditioned st...AyushGadhvi1
learning occurs when a stimulus (unconditioned stimulus) eliciting a response (unconditioned response) • is paired with another stimulus (conditioned stimulus)
10 Benefits an EPCR Software should Bring to EMS Organizations Traumasoft LLC
The benefits of an ePCR solution should extend to the whole EMS organization, not just certain groups of people or certain departments. It should provide more than just a form for entering and a database for storing information. It should also include a workflow of how information is communicated, used and stored across the entire organization.
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
- Video recording of this lecture in English language: https://youtu.be/Pt1nA32sdHQ
- Video recording of this lecture in Arabic language: https://youtu.be/uFdc9F0rlP0
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
How to Control Your Asthma Tips by gokuldas hospital.Gokuldas Hospital
Respiratory issues like asthma are the most sensitive issue that is affecting millions worldwide. It hampers the daily activities leaving the body tired and breathless.
The key to a good grip on asthma is proper knowledge and management strategies. Understanding the patient-specific symptoms and carving out an effective treatment likewise is the best way to keep asthma under control.
low birth weight presentation. Low birth weight (LBW) infant is defined as the one whose birth weight is less than 2500g irrespective of their gestational age. Premature birth and low birth weight(LBW) is still a serious problem in newborn. Causing high morbidity and mortality rate worldwide. The nursing care provide to low birth weight babies is crucial in promoting their overall health and development. Through careful assessment, diagnosis,, planning, and evaluation plays a vital role in ensuring these vulnerable infants receive the specialize care they need. In India every third of the infant weight less than 2500g.
Birth period, socioeconomical status, nutritional and intrauterine environment are the factors influencing low birth weight
Breast cancer: Post menopausal endocrine therapyDr. Sumit KUMAR
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
3. External Ear
Further divided into
Pinna or Auricle
External acoustic meatus
Tympanic membrane
1)Parts of pinna or arucle
Are shown
Except lobule and incisura terminalis
The whole pinna is made of up
Elestic cartilage cover with bone
4. External acustic meatus or canal.
It is about 24cm long. It’s outer 1/3 is cartilaginous while the inner 2/3 is bony.
It is not straight. Its Outer part is directed upward, backward and medially, While the
inner part is directed downward, forward and medially.
Cartilaginous part
Small hair and gland(secrets waxs) is mainly restricted to the outer 1/3(8cm) so furuncle
mainly develop here.
Slightly constricted are between the outer 1/3 and inner 2/3 is called isthmus where
forigen body mainly lodge.
5. Bony part
Its Form the inner 2/3 of external canal. Skin is not covered by hair and ceruminous
gland.
Anterioinferior part of the deep meatus beyond the isthmus present a recess called as
anterior recess where discharge and debris of external and middle ear accumulate.
6. Tympanic membrane
It is a partition between external acustic canal and middle ear.
It is set obliquely and has posterosuperior part lateral then the anterioinferior part.
It is about 9-10mm tall 8-9mm wide and 0.1mm thick.
It is divided into two parts
1)Pars tensa
1)Pars flaccida(Sharpnell’s membrane)
7.
8. 1)Pars Tensa
It form most of the tympanic membrane.
It’s pherephry is thicken to form a fibrocartilaginous ring called as anulus tympanicus.
It’s tent inword at the level of tip of malleus called as Umbo.
At the anterioinferior quadrant a bright Cone of light can be seen radiating from the tip
of malleus.
2)Pars Flaccida
It is satuited above the lateral process of malleus between the anterior and posterior
malleal fold
It is not taut and slightly reddish
9. Layer of tympanic membrane
Tympanic membrane consist of 3 layers
1) Outer epithelial layer, continues with skin of meatus.
2) Inner mucosal layer Which is cantinous with mucosa of the middle ear.
3) Middle fibrous layer, enclosed the hand of malleus.
Fibrous layer is thin in Pars Flaccida and is not well organized.
10.
11. Relations of External acustic canal
Superiorly: Middle cranial fossa
Inferiorly: Parotid glandl
Anteriorly: Temporomandibular joint
Posteriorly: Mastoid air cell and facial nerve
12. Nerve supply
Pinna
1. Great Auricluler nerve (C2,3) supply most of the medial side and only
the posterior part of lateral side.
2. Lesser occipital (C2) supplies upper part of medial surface.
3. Auriculotemporal (V3) supplies tragus, crus of helix and the adjacent
part of the helix.
4. Auricular branch of vagus (CN X), also called Arnold’s nerve, supplies the
concha and corresponding eminence on the medial surface.
5. Facial nerve, which is distributed with fibres of auricular branch of vagus,
supplies the concha and retroauaricular groove.
13. External auditory cana
Auriculotemporal (V3) supply roof and anterior wall.
Ariculer branch of vagus supply floor and posterior wall.
Posterior wall also receive sensery fiber of CN-7 through ariculer branch of vagus.
Tympanic membrane
Auriculotemporal (V3) supply anterior half
While Ariculer branch of vagus supply posterior half
Medial side is supply by tympanic branch of CN-9.
14.
15. MIDDLE EAR
The middle ear together with eustachian tube, aditus, antrum and Mastoid ear cell is
called middle ear cleft.
16. Middle ear
The middle ear extends much beyond the limits of tympanic membrane, and is sometimes
divided into:
1)Mesotympanum (lying opposite the pars tensa).
2) Epitympanium Or the Attic (lying above the pars tensa but medial to Shrapnell’s
membrane and the bony lateral attic wall)
3) Hypotympanum (lying below the level of pars tensa)
4)Protympanium The portion of middle ear around the tympanic orifice of the eustachian
tube are sometimes called as Protympanium.
17.
18. Middle ear is like a six sided box with roof, floor, medial, lateral, anterior and posterior walls
1) Roof: is form by a thin plate of bone called tegmen tympani. This bone separate middle
ear from middle cranial fossa.
2) Floor: It is also form by a thin plate of bone, It separate the tympanic cavity from jugular
bulb.
3) Anterior wall: It is also made by a thin plate of bone which separate the cavity from
Internal carotid artery. It also has two opening; the lower one for eustachian tube and the
upper one for the canal of tensor tympani muscle
4) Posterior wall: It lies close to the mostoid air cell. A bony projection pyramid is present
to which the tenden of Stapedius muscle attached. Aditus an opening through which attic
communicate with antrum is also present in the posterior wall. Facial recess is a depression in
the posterior wall lateral to the pyramid.
19. Medial wall: it is formed by the lybrinath. Basal coil of the cochlea formed buldge which is
called promontory.
Foot plate of stapis fixed to Oval window. While the Round window is covered by
secondary tympanic membrane.
Above the Oval window there is a canal for facial nerve. If the bone is congenitally defefient
then the facial nerve is vulnerable to infection of middle ear.
Above the canal for facial nerve there is a prominence of lateral semicircular canal.
Processus cochleariformis is a hook like projection in the medial wall anterior to the oval
window. The tensor tympani muscle tenden take trun here and It also marks the level of first
genu of facial nerve
20. Lateral wall: It is largely formed by tympanic membrane and to a lesser extent by a bony
outer attic wall called Scutum
21.
22. Mastoid antrum
It is a large air containg space in the upper part of Mastoid and
communicate with the attic through aditus
Its roof is formed by tegmen antro which is a continuation of tegmen
tympani and separate from middle cranial fossa.
23. Mastoid and its air system
Mastoid consists of bony cortex with a “honeycomb” of air cells underneath.
Depending on development of air cell, three types of mastoid have been described.
1. Well-pneumatized or cellular. Mastoid cells are well-developed and intervening septa
are thin.
2. Sclerotic or Acellular: There is no cell or marrow space.
3. Diploetic. Mastoid consists of marrow spaces and a few air cells.
With any type of mastoid pneumatization, antrum is always present.
In sclerotic mastoids, antrum is usually small.
Depending on the location, mastoid air cells are divided into:
1. Zygomatic cells (in the root of zygoma).
2. Tegmen cells (extending into the tegmen tympani).
3. Perisinus cells (overlying the sinus plate).
4. Retrofacial cells (round the facial nerve).
24. 5. Perilabyrinthine cells (located above, below and behind the labyrinth, some of them
pass through the arch of superior semicircular canal. These cells may communicate with the
petrous apex).
6. Peritubal (around the eustachian tube. Along with hypotympanic cells they also
communicate with the petrous apex).
7. Tip cells (which are quite large and lie medial and lateral to the digastric ridge in the tip
of mastoid).
8. Marginal cells (lying behind the sinus plate and may extend into the occipital bone).
9. Squamosal cells (lying in the squamous part of tempo-ral bones).
Abscesses may form in relation to these air cells and may sometimes be located far from
the mastoid region.
25.
26. Ossicles of middle ear
There are three ossicles in the middle ear, the malleus, incus and stapes.
The malleus has head, neck, handle (manubrium), a lateral and an anterior
process.
Head and neck of malleus lie in the attic. Manubrium is embedded in the
fibrous layer of the tympanic membrane.
The lateral process forms a knob-like projection on the outer surface of the
tympanic membrane and gives attachment to the anterior and posterior
malleal (malleolar) folds
27. The incus has a body and a short process, both of which lie in the attic, and a long process
which hangs vertically and attaches to the head of stapes
The stapes has a head, neck, anterior and posterior crura, and a footplate. The footplate is
held in the oval window by annular ligament.
The ossicles conduct sound energy from the tympanic membrane to the oval window and
then to the inner ear fluid.
28.
29. Intratympanic muscles
There are two muscles, tensor tympani and the stapedius,
Tensor tympani attaches to the neck of malleus and tenses the tympanic
membrane
Stapedius attaches to the neck of stapes and helps to dampen very loud
sounds thus preventing noise trauma to the inner ear.
Stapedius is supplied by a branch of CN VII while tensor tympani is
supplied by a branch of mandibular nerve (V3)
30. Lining of middle ear cleft
Mucous membrane of the nasopharynx is continuous with that of the middle ear, aditus,
antrum and the mastoid air cells. It wraps the middle ear structures: the ossicles,
muscles, ligaments and nerves.
Middle ear cantain nothing but air. And All the structure lie outside mucous membrane.
Histologically eustachian tube is lines by Cilliated Epithelium, pseudostratified columnar
in cartilaginous part and simple columnar in bony part
Tympanic membrane epithelium-anterior part: Cilliated columnar and posterior part
Cuboidal.
Epitympanium and Mastoid air cell is lined by noncilliated epithelium.
31. Inner ear
The internal ear or the labyrinth is an important organ of hearing and
balance.
It consists of a bony and a membranous labyrinth.
The membranous labyrinth is filled with a clear fluid called endolymph
while the space between membranous and bony labyrinths is filled with
perilymph.
32. Bony labyrinth
It consists of three parts: the vestibule, the semicircular canals and the cochlea
33. Vestibule:
It is the central chamber of the labyrinth.
In its lateral wall lies the oval window.
The inside of its medial wall presents two recesses, a spherical recess, which lodges the
saccule, and an elliptical recess, which lodges the utricle.
Below the elliptical recess is the opening of aqueduct of vestibule through which passes
the endolymphatic duct.
In the posterosuperior part of vestibule are the five openings of semicircular canals
34. Semicircular canals:
They are three in number, the lateral, posterior and superior, and lie in planes at right
angles to one another.
Each canal has an ampullated end which opens independently into the vestibule and a
nonampullated end.
The nonampullated ends of posterior and superior canals unite to form a common
channel called crus commune.
Thus, the three canals open into the vestibule by five openings.
36. Cochlea:
The bony cochlea is a coiled tube making 2.5 to 2.75 turns round a central pyramid of
bone called modiolus.
The base of modiolus is directed towards internal acoustic meatus and transmits vessels
and nerves to the cochlea.
Osseous spiral lamina is thin plate of bone which divides the cochlea incompletely and
give attachment to basilar membrane.
Promontory is due to basal coil of cochlea
Bony cochlea has 3 compartments
1)Scala vestibuli
2)Scala tympani
3) Scala media or the membranous cochlea.
37. The scala vestibuli and scala tympani are filled with perilymph and communicate with
each other at the apex of cochlea through an opening called helicotrema.
Scala vestibuli is closed by the footplate of stapes which separates it from the air-filled
middle ear. The scala tympani is closed by secondary tympanic membrane
It is also connected with the subarachnoid space through the aqueduct of cochlea
38.
39.
40. Membraneous labyrinth
It consists of the cochlear duct, the utricle and saccule, the three semicircular ducts, and
the endolymphatic duct and sac.
1) Cochlear Duct:
It is Also called membranous cochlea or the scala media
It is a blind coiled tube.
It appears triangular on cross-section and its three walls are formed by:
A)The basilar membrane, which supports the organ of Cort.
B)The Reissner’s membrane, which separates it from the scala vestibule.
C)The stria vascularis, which contains vascular epithelium and is concerned with secretion of
endolymph.
Cochlear duct is connected to the saccule by ductu reuniens. The length of basilar membrane
increases as we proceed from the basal coil to the apical coil.
It is for this reason that higher frequencies of sound are heard at the basal coil while lower
ones are heard at the apical coil
41. 2)Utricle and Saccule. The utricle lies in the posterior part of bony vestibule.
It receives the five openings of the three semicircular ducts. It is also connected to the
saccule through utriculosaccular duct.
The sensory epithelium of the utricle is called macula and is concerned with linear
acceleration and deceleration.
The saccule also lies in the bony vestibule, anterior to the utricle and opposite the stapes
footplate.
Its sensory epithelium is also called macula. Its exact function is not known. It probably
also responds to linear acceleration and deceleration
42. 3)Semicircular Ducts:
They are three in number correspond exactly to the three bony canals.
They open in the utricle.
The ampullated end of each duct contains a thickened ridge of neuroepithelium called
crista ampullaris.
43. 4)Endolymphatic Duct and Sac:
Endolymphatic duct is formed by the union of two ducts, one each from the saccule and the
utricle.
It passes through the vestibular aqueduct.
Its terminal part is dilated to form endolymphatic sac, which lies between the two layers of
dura on the posterior surface of the petrous bone.
Endolymphatic sac is surgically important. It is ex-
posed for drainage or shunt operation in Ménière’s disease.
44. Inner ear fluid and their circulation
There are two main fluids in the inner ear: perilymph and endolymph.
1) Perilymph:
It resembles extracellular fluid and is rich in Na ions. It fills the space between the bony
and the membranous labyrinth.
It communicates with CSF through the aqueduct of cochlea which opens into the scala
tympani near the round window. In fact this duct is not a direct communication but
contains connective tissue resembling arachnoid through which perilymph percolates.
There are two views regarding the formation of perilymph:
1) It is a filtrate of blood serum and is formed by capillaries of the spiral ligament.
2) it is a direct continuation of CSF and reaches the labyrinth via aque-duct of cochlea
45. 2) Endolymph:
It fills the entire membranous labyrinth and resembles intracellular fluid, being rich in K
ions.
It is secreted by the secretory cells of the stria vascularis of the cochlea and by the dark
cells (present in the utricle and also near the ampullated ends of semicircular ducts).
There are two views regarding its flow:
(i) longitudinal, i.e. endolymph from the cochlea reaches saccule, utricle and
endolymphatic duct and gets absorbed through endolymphatic sac, which lies in the
subdural space.
(ii) radial, i.e. endolymph is secreted by stria vascularis and also gets absorbed by the
stria vascularis.
46. Labyrinth blood supply
The entire labyrinth receives its arterial supply through labyrinthine artery,
which is a branch of anterior-inferior cerebellar artery but sometimes from the
basilar.
In the internal auditory canal it divides in the manner shown in Venous
drainage is through three veins, namely internal auditory vein, vein of cochlear
aqueduct and vein of vestibular aqueduct, which ultimately drain into inferior
petrosal sinus and lateral venous sinus
It is to be noted that:
1) Blood supply to the inner ear is independent of blood supply to middle ear
and bony otic capsule, and there is no cross circulation between the two.
2) Blood supply to cochlea and vestibular labyrinth is segmental, therefore,
independent ischaemic damage can occur to these organs causing either
cochlear or vestibular symptoms.
50. AUDITORY SYSTEM
ORGAN OF CORTI ; THERE ARE THE FOLLOWING 4 PARTS OF THE ORFGAN OF CORTI
1. TUNNEL OF CORTI ;
TUNNEL OF CORTI CONTAINS CORTILYMPH
2. HAIR CELLS ;
THEY ARE IMPORTANT RECEPTOR CELLS OF HEARING AND TRANSDUCE SOUND ENERGY
INTO ELECTRICAL ENERGY .
A;INNER HAIR CELLS
FORM A SINGLE ROW IT IS HIGHLY SUPPLIED WITH AFFERENT COCHLEAR FIBERS AND GIVES
SIGNELS TO BRAIN
B; OUTER HAIR CELL
OUTER HAIR CELLS RECEIVE EFFERENT FIBERS FROM OLIVERY COMPLEX AND IS CONCEREND
WITH MODULATING THE FUNCTION OF INNE RHAIR CELLS
51. 3 SUPPORTING CELL;
THERE ARE TWO TYPES OF SUPORTING CELLS DIETER,S CELL AND HENSEN CELLS
4 TECTORIAL MEMBRANE ;
IT OVERLIES THE ORGAN OF CORTI .
THE SHEARING FORCE BETWEEN THE HAIR CELLS AND TECTORIAL MEMBRANE PRODUCES
THE STIMULUS TO HAIR CELLS
NERVE SUPPLY OF HAIR CELLS ;;
95 %OF AFFERERNT FIBERS OF SPIRAL GANGLION SUPPLY INNNER HAIR CELLS WHILE
5%SUPPLY THE OUTER HAIR CELLS
EFFERENT FIBRS TO HAIR CELLS COM FROM OLIVOCCHLEAR BUNDLES .THE CELL BODIES OF
THESE FIBERS ARE LOCATE IN THE SUPERIOR OLIVERY COMPLEX
EACH COCHLEA SENDS FIBERS TO BOTH SIDES OF BRAIN
52.
53. AUDITORY NEURAL PATHWAYS AND THEIR NUCLIE ;;
HAIR CELLS ARE INNERVATED BY DENDRITES OF BIPOLAR CELLS OF SPIRAL GANGLION
WHICH IS INNERVATED BY ROSENTHAL,S CANAL
AXONS OF THESE BIPOLAR CELLS FORM THE COCHLEAR DIVISION OF CN VIII AND END IN
COCHLEAR NUCLIE THE DORSAL AND VENTRAL ON EACH SIDE OF MADULLA
THE ASCENDING PATHWAY SEQUENTIALLY FROM BELOW TO UPWORD
SUPERIOR OLIVERY NUCLEUS
NUCLEUS OF LATERAL LIMNISCUS
INFERIOR COLLICULUS
MEDIAL GENECULATE BPDY
AUDITORY CORTEX
THE AUDITORY FIBERS TRAVEL VIA IPSILATERAL AND CONTRALATERAL ROUTES AND HAVE
MANY DECUSSATION POINTS
BROADMAN AREA ;; IT IS THE CEREBRAL PORTION CONCERNED WITH HEARING
54. MECHANISM OF HEARING
SOUND IS SIGNAL IS COLLECTED BY THE PINNA OF EAR PASSES THROUGH THE XTERNAL
CANAL IT REACHES THE TEMPANIC MEMBRANE AND STRIKES IT
TEMPANIC MEMEBRANE GIVES THESE VIBRATIONS TO MELLIUS AND THEN TO INCUS AND
LASTLY GIVEN TO STAPES
STAPES GIVES THESE SIGNALS TO LABIRYNTHINE OF INNER EAR HICH CONVERTS THESE
SIGNALS TO ELECTRICAL SIGNALS WHICH ARE THEN TRANSMITTED THROUGH VIII NERVE
TO BRAIN
PAYHWAYS OF TRANSMISION
MECHNICAL CONDUCTION ( CONDUCTIVE APPARATUS )
ELECTRICAL CONDUCTION ( SENSORY SYSTEM OF COCHLEA )
CONDUCTION OF ELECTRICAL SIGNALS TO BRAIN ( NEURAL PATHWAY )
55.
56. IMPEDENCE ;; IMPEDENCE IS THE RESISTANCE SHOWN TO SOUND WAVES WHEN IT ENTERS
FROM ONE MEDIUM TO ANOTHER MEDIUM
MECHANISM OF IMPEDENCE ;;
• LEVER ACTION OF OSSICLES ; HANDLE OF MALLEUS IS 1.3 TIMES LONG THAT IS WHY IT
PROVIDES MECHANICAL ADVANTAGE OVER STAPES
• HYDRUALIC ACTION OF TYMPANIC MEMBRANE ;; AREA OF TYMPANIC MEMBRANE IS
LARGER THAN THE AREA OF STAPES FOOTPLATE
• CURVED MEMBRANE EFFECT OF TYMPANIC ; MOVEMENT OF TYPANIC IS MORE AT THE
PERIPHERY THEN AT THE CENTER
57. VESTIBULAR SYSTEM
THIS SYSTEM IS MAINLY CONCERNED WITJH BALANCE AND POSITION OF BODY
IT HAS THE FOLLOWING PARTS .
PERIPHRAL RECEPTORS ; THERE ARE TWO TYPES OF RECEPTORS
• CRISTEA ; THEY ARE LOCATED IN THE SEMICIRCULAR CANAL
• THEY RESPOND TO ANGULAR MOTIONS
• MACULA ;; THEY ARE PRESENT IN THE OTOLITH ( UTRICLES AND SACCULES )
• MACULA OF UTRICLE LIES THE FLOOR IN HORIZONTAL PLANE
• MACULA OF SACCULE LIES IN MEDIAL WALL IN VERTICAL PLANE
THEY SENSE POSITION OF HEAD IN RESPONSE TO GRAVITY AND LINEAR ACCELERATION
58.
59. VESTIBULAR NERVE ;;
THE VESTIBULAR GANGLION IS LOCATED IN THE LATERAL PART OF INTERNAL ACOUSTIC
MEATUS
IT CONTAINS BIPOLAR CELLS
THE DISTAL PROCESSES OF BIPOLAR CELLS INNERVATE THE SENSORY EPITHELIUM OF
LABYRINTH
THE CENTRAL PROCESSES AGREGATE TO FORM VESTIBULAR NERVE
VESTIBULAR NUCLIE ;;;
THEY ARE LOCATED IN THE MADULLA AND PONS OF HIND BRAIN
THEY ARE FOUR IN NUMBER
• SUPERIOR
• INFERIOR
• MEDIAL
• LATERAL