This document discusses ductless hoods as an alternative to traditional ducted fume hoods for laboratory ventilation. It provides examples of when ductless hoods may be preferable, such as when building limitations prevent ducting or when chemical usage is minimal. The key considerations for using ductless hoods include conducting a hazard assessment, selecting the appropriate filter type, and implementing controls like service contracts, pressure gauges, signage and training. Case studies demonstrate how ductless hoods have been used successfully in situations involving limited chemical usage.