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- 1. DRUG BOOK SIGNATURE OF SUBJECT COORDINATOR SIGNATURE OF EXTERNAL SIGNATURE OF INTERNAL
- 2. INDEX
- 3. SR.NO NAME OR CLASSIFICATIONS NAME OF THE DUG 1 ANALGESICS AND ANESTHETICS ACETAMINOHEN ASPIRIN FENTANYL IBUPROFEN KETAMINE MIDAZOLAM PROPOFOL 2 ANTICONVULSANTS PHENYTOIN PHENO BARBITOL SODIUM VALPROATE CARBOMAZEPINE 3 ANTI COAGULANTS HEPARIN WARFARIN
- 4. 4 ANTIHYPERTENSIVE ATENDOL PROPRANOLAL NEFEDIPINE VERAPAMIL 5 DIURETICS ACETAZOLAMIDE FRUZEMIDE MANNITOL SPIRANOLACTONE 6 VASODILATORS SODIUM NITROPRUSSIDE HYDRALAZINE 7 ANTI TUBERCULOSIS DRUGS ISONIAZID PYRAZINAMIDE RIFAMPICIN ERYTHROMYCIN
- 5. 8 ANTI LEPROSY DRUGS DAPSON 9 BROCHO DILATORS SALBUTAMOL ATROPINE SULPHATE TERBUTALINE 10 ANTI MALARIAL DRUGS CHLOROQUININE PHOSPHATE PRIMAQUININE PHOSPHATE 11 ANTIVIRALS ACYLOVIR RIBOVIRIN ZIDOVUDINE 12 CARDIOTONICS DGOXIN
- 6. 13 ANTI BIOTICS AMPICILLIN PENCILLIN TETRACYCLIN HYDROCHLORIDE CEFOTAXIM 14 ANTI RETROVIRALS INOINAVIR SULPHATE ZINDOVUDINE 15 ANTI NEOPLASTIC DRUGS CYCLO PHOSPHAMIDE VINCRISTINE SULPHATE
- 8. SL NO. NAME OF DRUG TRADE NAME ROU TE DOSE MODE OF ACTION INDICATI ON CONTRAINDI RATION SIDE EFFECT NURSING RESPONSI BILITIES 1 ACET AMIN OPHE N AASE AEGI NA ORA L 300M g It exhibits analysis action by peripheral blockage of pain impulse generation It produces antipyretics effect by inhibiting the hypothalam ic heart regulation center. Mild, moderate pain Post impyrexi a Rheumat ic fever Hypersensiti vity Nausea Vomiting Allergic reaction Skin rashes Diarrhea Ulceration Perforatio n Hemaehag e Neurosis Aplastic anemia Check for any C.I Check for any adverse reaction. Follow the principle s of drug administr ation.
- 9. 2 aspirin Arced Oral 3-25 mg 80- 100- mg/kg It inhibits analgesic action by antipyretic action A non- steroidal salicylate that inhibits prosta glandins synthesis acts on the hypothalam us heart regulating center. A substance that stimulate platelet aggregates. It reduces inflammatio n, pain, decreases fever. Analgesia Fever MI Stroke Ischemic attack Kawasaki disease Hypersensitivi ty Bleeding disorders Chicken ox GI bleeding o ulceration Hepatic impairment Allergy Pregnancy lactation GI distress Allergic reaction Bronchospa sm Pursuits Urticaria Headache Tinnitus Difficulty in hearing Lethargy Confusion Drowsiness’ Use liquid form for children & patient who are difficulty in swallowing In children don’t exceeds five dos in 24hrs Check vital signs Chick for any rashes
- 10. SL NO. NAME OF DRUG TRAD E NAME ROUTE DOSE MODE OF ACTION INDICA TION CONTRAIND IRATION SIDE EFFECT NURSING RESPONSI BILITIES 3 IBUPR OFEN - 8-12mg 600-8— mg 0.4- 0.6gm Iv Oral It Is a synthetic compound having analgesic & mid anti- inflammatory effect Fever pain a cute peptic ulcer gastric irritation dyspnea GI bleeding jaundice check for side effects
- 11. SL NO. NAME OF DRUG TRAD E NAME ROU TE DOSE MODE OF ACTION INDICATI ON CONTRAI NDIRATIO N SIDE EFFECT NURSING RESPONSI BILITIES 4 FENT ANYL fend cap O IV 0.5- 3mg/kg 0.5- 1mg/kg it inhibits prostaglandi n synthesis pain anesthesia hypersensit ivity dyspnea peptic ulcer rhinitis nausea vomiting check for any side effect & adverse reaction assess vital signs regularly
- 12. SL NO. NAME OF DRUG TRAD E NAME ROU TE DOSE MODE OF ACTION INDICATI ON CONTRAI NDIRATIO N SIDE EFFECT NURSING RESPONSI BILITIES 5 PROP OFOL - IV 1- 2mgl/kg It Is an liquid used as 1% emulsion. It is used for i.v indication & short duration anesthesia. Sedation ECT hypersensit ivity nausea vomiting pain headache involuntary muscle contraction check for any side effect monitor vital signs
- 13. ANTI CONVULSANT
- 14. SL NO. NAME OF DRUG TRAD E NAME ROU TE DOSE MODE OF ACTION INDICAT ION CONTRAIN DIRATION SIDE EFFECT NURSING RESPONSI BILITIES 1 PHEN YTOIN EPTOI N Oral 5 mg/kg May stabilize neuronal and limit seizure activity either by increasing influx of ion across the cell membrane is to monitor cortex of nerve impulse Tonic clone seizure Static epilepti cs Hypersensiti vity Hepatic dysfunctio n Hypotension Respiratory depression Ataxia Diplopia Vomiting Constipation Toxichepatit es don’tgive IM unless dosage adjustment Divided dosegive with or after meal. Don’t stop drug suddenly Monitor drug level.
- 15. SL NO. NAME OF DRUG TRAD E NAME ROUTE DOSE MODE OF ACTION INDICAT ION CONTRAIND IRATION SIDE EFFECT NURSING RESPONSI BILITIES 2 Sodium valproa te - Oral/IV 10-15 mg/kg Unknown facilitated the effects to inhibit neuron transmitter GABA Sample complex seizure Mixed seizure type Hypersen situity Hepatic disease Children younger than 10years Urea cycle disorders Dizziness Headache Insomnia Chest pain Hypertensio n Blurred vision Abdominal pain Anorexia Diarrhea Alopecia Obtain lives function test Monitor drug level Tell patient to take drug c food/milk to reduce and verse GJ effect.
- 16. SL NO. NAME OF DRUG TRA DE NAM E ROU TE DOSE MODE OF ACTION INDICATI ON CONTRAIND IRATION SIDE EFFECT NURSING RESPONSI BILITIES 3 Diaz epam - IV/IM oral 0.12- 0.8 mg/kg/ day 0.04- 0.3 mg/kg A benzodiazepin e that depresses all levels of the CNS by enhancing the action of gamma amino butyric acid, a major inhibitory neurotransmitt er in the brain It produces anxiolytic effect, elevates the seizure threshold Cough Anxiety Skeletal muscle relaxation Preanesthe sia Alcohol arthdeval Status epileptics Hypersensitiv ity Angle closure glaucoma Coma CNS depression Respiratory depression Sever uncontrolled pain Pain IM injection Somnolenc e Fatigue Ataxia Slurred speech Headache Constipatio n Nausea Blurred vision When the patient have sudden change of position can cause of zziness In street the patient to avoid alcohol while taking diazepam Monitor vital signs.
- 17. ANTIBIOTICS
- 18. SL NO . NAME OF DRUG TR AD E NA ME ROU TE DOSE MODE OF ACTION INDICATI ON CONTRAIND IRATION SIDE EFFECT NURSING RESPONSI BILITIES 1 AMPICI LLIN - ORAL /IV 25- 30mg/k g Inhibit cell- wall synthesis during bacterial multiplication. UTI G1 infection Skin infection Hypersensitiv ity Seizure Lethargy Vomiting Diarrhea Nausea Anaxity Confusion Before giving drug ask Pt about degree of reaction to penicillin Monitor Na+ level
- 19. SL NO . NAME OF DRUG TR AD E NA ME ROU TE DOSE MODE OF ACTION INDICATI ON CONTRAIN DIRATION SIDE EFFECT NURSING RESPONSIBI LITIES 2 Penicil lin - IV/1m l oral 500mg It is bind to the bacterial cell wall synthesis. The protects the penicillin from enzymatic degradation. Respirator y infection UTI Meningoc occal infection hypersensiti vity seizure diarrhea nausea vomiting headache oral or vaginal candidiasis anemia monitor the patients pulse & B.P notify the vomiting or diarrhea monitor respiratory rate& any rashes Cheek for any side effect.
- 20. SL NO . NAME OF DRUG TRA DE NAM E ROU TE DOSE MODE OF ACTION INDICATI ON CONTRAIND IRATION SIDE EFFECT NURSING RESPONSI BILITIES 3 AMIKA CIN Amik in IV/IM 250 mg for 12hrs It is an aminoglycoside antibiotic that irreversibly binds to protein or bacterial ribosomes. Interferes protein synthesis of susceptible microorganism Typhoid Bronchitis UTI Hypersensitiv ity Pain in duration Thromboph lebitis Difficulty in breathing Drowsiness Weakness Monitor patient for swelling Monitor respiratory rate. Monitor urine output Monitor the patient pulse & B.P
- 21. SL NO . NAME OF DRUG TR AD E NA ME ROU TE DOSE MODE OF ACTION INDICATI ON CONTRAIND IRATION SIDE EFFECT NURSING RESPONSI BILITIES 4 TETRAC YCLIC HYDRO CHLOID E - Oral 25- 30mg/k g May exert bacteriostatic effect by binding to protein or bacterial ribosomes. They inhibit protein synthesis. Grana positive infections Rectal infection n Urethral & endo- cervical infection Soretheoat Glossites Diarrhea Hypersensitiv ity Nausea Vomiting Skin rashes Obtain specimen for culture & sensitivity. Check patient tongue for infection Check for any side effect
- 22. ANTI COAGULANTS
- 23. SL NO . NAME OF DRUG TR AD E NA ME ROU TE DOSE MODE OF ACTION INDICATI ON CONTRAIND IRATION SIDE EFFECT NURSING RESPONSI BILITIES 1 HEARIN - IV 25- 50units /kg hr Accelerator reaction of anti-thrombin complex and deactivates thrombin preventing of fibrinogen to fibrin. Pulmonary embolism Deseirited intravascu lar coagulati on. Hypersensitiv ity Active bleeding Ascorbic acid deficiency Fever Rhinitis Irritation Peuritis Cut Icaria Dew blood to establishes baseline coagulatio n before therapy . Check vital
- 24. SL NO . NAME OF DRUG TR AD E NA ME ROU TE DOSE MODE OF ACTION INDICATI ON CONTRAIND IRATION SIDE EFFECT NURSING RESPONSI BILITIES 2 WARFA RIN
- 26. SL NO . NAME OF DRUG TRA DE NAM E ROU TE DOSE MODE OF ACTION INDICATI ON CONTRAI NDIRATI ON SIDE EFFECT NURSING RESPONSIBI LITIES 1 Epineph rine - 1m, sc IV 0.2- 0.5 ml 0.25m g It has stimulant action on predominant B receptor It dilates the blood vessels of the skeletal muscle on account of predocinderent of B2 receptor. It increases heart rate & myocardial contractility. Anaphylac tic shock Bronchial asthma Cardiac resusutati on Open angle gleeman Angoneur otic edema of larynx Vertigo hypotensio n Hypotension Palpation Angina Nausea Headache Vomiting Sweating Use extrence caution in alkylate & preparing doses Any solution of adrenaline that is teen to panic should not be given. Bp should be cheeked energy 15minuts.
- 27. SL NO . NAME OF DRUG TRA DE NAM E RO UTE DOSE MODE OF ACTION INDICATI ON CONTRAI NDIRATI ON SIDE EFFECT NURSING RESPONSIBI LITIES 2 Propran olol - Oral 0.5- 1mg/k g/day An anti- hypertensive, antianginal, antiarrhythmic, & ant migraine agent that blocks beta1,beta2, adrenergic receptors. It decreases oxygen requirements. It slows Av conduction. Therapeutic effect: decreases cardiac out put Angina Arrhythmi c Hypertrop hy sub aortic stenosis. Migraine headache MI Essential tremors Asthenia Beady card Cardiogen ic shock Raynaud & syndrome CHF Pregnancy Lactation Diminished sexual ability Drowsiness Difficulty sleeping Unusual fatigue Beady cardiac Depression Diarrhea Anxiety Pruritus Always cheek patents apical pulse before giving drug. Pulse rate occurs a rolel drug & notify pees cubes incredibly Give drug consistently meals foods. May increase absorption of propranolol
- 28. SL NO . NAME OF DRUG TRA DE NAM E RO UTE DOSE MODE OF ACTION INDICATI ON CONTRAI NDIRATI ON SIDE EFFECT NURSING RESPONSIBI LITIES 3 AMLO DIPINE - oral 5- 10mg It has antianginal antihypertensive actor A calcium channel blockers that inhibits ca moucment across cardiac &vascular smooth cell membrane. Therapeutic effect decreases peripheral vascular resistance & BP by vasodilation. Hypertensi on Angina Renal inepairien t Hyper sensitivity Severe hypotension Aortic stenosis Heart failure Severe hepatic diseases Peripheral edema Headache Flushing Dizziness Palpitation Nausea Fatigue Chest pain Beady cardia Orthostatic hypotension Tel the patient to take nitroglycerine for acute angina symptoms. Notify cline of irregular heartbeat, shortness of breath, shortness of breath , swelling of feet, hand etc. Monitor BP continuously.
- 29. SL NO . NAME OF DRUG TRAD E NAME ROU TE DOSE MODE OF ACTION INDICATI ON CONTRAI NDIRATI ON SIDE EFFECT NURSING RESPONSIBI LITIES 4 HYDR ALAZI NE - Oral/ IV 0.75- 1mg/k g/day An anti- hypertensive direct vasodilating effects on arterials. Therapeutic effect: decreases BP & resistance. Hypertensi on Failure of heart Hypersens itivity Coronary artery disease CNA Renal caiemant Headache Palpitation Tachycardi a GI disturbances Nausea Vomiting Peripheral ederea Dizziness Nasal congestion Flushed face CBC, left cell purparation & ANA litxe diter mination should be performed before surgery Advise precaution from orthostatic hypotension. For IV use monitor BP every 5minutes
- 30. DIURETICS
- 31. SL NO . NAME OF DRUG TRA DE NAM E RO UTE DOSE MODE OF ACTION INDICATI ON CONTRAI NDIRATI ON SIDE EFFECT NURSING RESPONSIBI LITIES 1 FUOSE MIDE - Oral/ IV/ IM 1- 6mg/kg day in 6-12 hr 1-2 mg/kg (IV,IM) Aldop duretic that enhances excretion of sodium chloride & potassium by direct action at the ascending liner of the loop of Henley It produces decrees & lower BP Edema Hypertensi on Anuria Hepatic coma Sever electrolyte depletion Pregnancy lactation increased urinary frequency nausea dyspepsia abdominal camps diarrhea constipation electrolyte disturbance dizziness to prevent nocturia give PO&IM preparation on the morning monitor fluid intake & output electrolytes, BUN & co2 level frequency watch for s/s of hypokalemia monitor glucose level in DM patient
- 32. SL NO . NAME OF DRUG TRA DE NAM E RO UTE DOSE MODE OF ACTION INDICATI ON CONTRAI NDIRATI ON SIDE EFFECT NURSING RESPONSIBI LITIES 2 SPIRON OLACT ONE - PO 1.5-3.3 mg/kg/d ay in 1- 2 divided doses an potassium sparing durative that intefeve sodium reabsorption by competitively inhibiting the action of aldosterone in the distal tubule, this promoting Na & H2o excretive & it produce diuresis lower BP edema hypertensi on hirsutine mypolcale nier primacy aldostero ne acute renal insufficienc y anuria BUN & serum creatin level increase Hyperkale mia Pregnancy Lactation Hypertension dehydration nausea lethargy dyspepsia abdominal camps diarrhea constipation confusion Assess the patent actually Monitor vital signs Cheek for any rashes Cheek for abdominal discomfort Give the drug meals to enhance the absorption Instruct the patient to report mental confusion
- 33. SL NO . NAME OF DRUG TRA DE NAM E RO UTE DOSE MODE OF ACTION INDICATI ON CONTRAI NDIRATI ON SIDE EFFECT NURSING RESPONSIBI LITIES 3 TRIAM TEREN E - Oral 2-4 mg/kg/d ay in single dose A potassium sparing directive that inhibits sodium, potassium ATPase It increases odium & decreases potassium excretion It produces decreases & lowers BP Edema Hypertensi on Hyperkale mia Renal disease Hepatic disease Pregnancy lactation fatigue nausea diarrhea abdominal pain leg cramps headache anorexia rash dizziness ECG changes Assess the patient actually Monitor vital signs Cheek for any rashes Monitor ECG Monitor BUN & creatin level Cheek for fluid electrolyte imbalance
- 34. SL NO . NAME OF DRUG TRA DE NAM E RO UTE DOSE MODE OF ACTION INDICATI ON CONTRAI NDIRATI ON SIDE EFFECT NURSING RESPONSIBI LITIES 4 XIPAMI DE - Oral 10- 20mg It is peniacysite of action is the cortical segment of early distal tubes. If inhibit sodium reabsorption, choice & water are retained in the tubule secondly Relaxant effect on arterioles & elevation of blood. Edema Hepatic crepauien t Renal crepavierien t Acute electrolyte unbalance Cirrhosis of lives Weakness Fatigue Muscle camp GI disturbance Hearing loss Monitor vital signs Monitor patient for allergic reaction Monitor to chart Provide right dosage at right time.
- 35. VASODILATOR
- 36. SL NO . NAME OF DRUG TRA DE NAM E RO UTE DOSE MODE OF ACTION INDICATI ON CONTRAI NDIRATI ON SIDE EFFECT NURSING RESPONSIBI LITIES 1 SODIUM NITROP RUSSID E - IV/ oral 2.5-10 mg/kg A potent vasodilation used to treat energy hypertension condition It acts directly on arterial & venous smooth muscle Decreases peripheral vascular resistance . Improves cardiac outputs BP in hypertoni c crisis Controlled hypertens ion in surgical procedure Acute CHF Hypersens itivity Compensa tory HTN Increased ICP Fleshing of skin Increased intracranial pressure Rash Pain & redness in infection site. Monitor the vital for every ½ hourly Monitor cardiac output Cheek the patient infection site for any Pain redness are present or not
- 37. SL NO . NAME OF DRUG TRA DE NAM E RO UTE DOSE MODE OF ACTION INDICATI ON CONTRAI NDIRATI ON SIDE EFFECT NURSING RESPONSIBI LITIES 2 HYDRA LAZINE - Oral 0.75-1 mg /kg/day An anti- hypertensive direct vaso dilating effects on bacterial Therapeutic effect decreases BP and systemic resistance Severe hypertens ion Angina Coronary artery disease leepus erythematou s headache palpitation tachycardia nausea vomiting parenthesis fluid cetertion peripheral edema Dizziness Flushed face Nasal congestion Advise the patient to take the drug meals Notify clinical of any unrespects prolonged general tiredness or fever muscle or join aching or chest pain Cheek the stools Advise precaution for orthostatic hypotension
- 39. SL NO . NAME OF DRUG TRA DE NAM E RO UTE DOSE MODE OF ACTION INDICATI ON CONTRAI NDIRATI ON SIDE EFFECT NURSING RESPONSIBI LITIES 1 DAPSO NE - Oral 1m 100mg 0.5ml/ 0.2ml Bacteriostatic activity It acts by inhibiting the de-noro synthesis of folic acid by M.cepeai The action is antagonist by Para aminodizolic acid Anti lepeotic uses Dermatitis Hypersens itivity Infant younger than 2months Hemolytic anemia lever & kidney damage allergies reaction nausea jaundice vomiting before administrati ng the drug ask the patient for any allergic reaction to drug monitor 1/0 chart cheek for any side effects
- 41. SL NO . NAME OF DRUG TRA DE NAM E RO UTE DOSE MODE OF ACTION INDICATI ON CONTRAI NDIRATI ON SIDE EFFECT NURSING RESPONSIBI LITIES 1 CHLOR OQUINE PHOSPH ATE ARAL EN Oral 10mg/ kg it is a 4 amino quinolone derivative it has a suppressive effect like quinine it acts by inhibiting the incorporation of phosphate into RNA & DNA of plasmodia’s. Acute malaria Extra intestinal a moebiasis Giardiasis Taeneasis Arthritis Hypersens itivity Skin rashes Bleaching of scalp, nose, eye lashes Visual distributes Blurred vision Diplopia Psychotic episodes Abdominal cramps Anemia Monitor complete blood count Ensure that periodic visual or ophthalmic examination are performed Monitor lever function test. Check for any side effect Check vital signs
- 42. SL NO . NAME OF DRUG TRA DE NAM E RO UTE DOSE MODE OF ACTION INDICATI ON CONTRAI NDIRATI ON SIDE EFFECT NURSING RESPONSIBI LITIES 2 DRIM AQUIN EPHOS PHAT E - Oral 3mg/da y It belongs to the group of 8 aminoquinolines If acts on the exocrytheocytes cycle & on ganeeto cycle Sonceof the ganutocyteace destroyed The remaining cannot mature in the mosquito Malaria A granule cytosols Rheumatoi d arthritis Nausea Vomiting Epigastric disteriess Leukopenia Anemia Guie the drug by follow 6 dights Cause the drug after meals. Obtain frequent blood studies Cheek vital signs Cheek for any side effect
- 43. ANTI – T.B DRUGS
- 44. SL NO . NAME OF DRUG TRA DE NAM E RO UTE DOSE MODE OF ACTION INDICATI ON CONTRAI NDIRATI ON SIDE EFFECT NURSING RESPONSIBI LITIES 1 Pyrazina mide - Oral 20-30 mg/kg body wt is 3-4 divided closed max of 3 gm daily It is the pyrozine analogue of nuotinnude When the drug is used alone the diseases is initially contracted but soonrelapses because microorganisms rapidly resistant When it is administered de multineouslt inoicazis the bacteria is sensitive. Tuberculo sis Hypersens itivity Aethealgeas Nausea Vomiting Dysuria Malaria fever Elevation of plasma uric acid Acute episodes of gout. Reduces serve 1NH concentratio n Cheek vital signs Cheek for any side effect Observe cough
- 45. SL NO . NAME OF DRUG TRA DE NAM E ROU TE DOSE MODE OF ACTION INDICATION CONTRAI NDIRATI ON SIDE EFFECT NURSING RESPONSIBIL ITIES 2 ERYTH ROMYC IN - Oral 250m g/kg It mainly acts on gram +ve cocci It acts against penicillin resistant staphylococc i. URTI Acute pneumonia Vaginitis Impetigo Wound & burn infection Whooping cough Hypersens itivity Mild to sense epigastria pain Diarrhea Other allergic reactions May increases serve digoxin Level so the nurses should be aware about it. It reduces the therapeutic effect of penicillin terferadine & astinizole It increases the risk of the adverse effect on the heat so cheek continuously.
- 46. SL NO . NAME OF DRUG TRA DE NAM E RO UTE DOSE MODE OF ACTION INDICA TION CONTRAIN DIRATION SIDE EFFECT NURSING RESPONSIBI LITIES 3 ETHA MBUT O HYDR OCHL ORIDE - Oral 15 mg/kg May inhibit synthesis of on or more metabolites of susceptible bacteria changing al metabolism during division. Pulmon ary TB Children younger than 13 years hypersensitiv ity headache optic nutritive anemia nausea GF upset Joint paint. Perform visual aquity test & Coloma that before & dividing therapy. Ensure any change in vision Cheek any other side effects
- 47. SL NO . NAME OF DRUG TRA DE NAM E RO UTE DOSE MODE OF ACTION INDICA TION CONTRAIN DIRATION SIDE EFFECT NURSING RESPONSIBI LITIES 4 ISONI AZID Isota mine Oral 10-15 mg/kg May inhibit all wall biosynthesis by interfering rapid & DNA synthesis Activity growin g tubercl e bacilli. Acute rap tie disease Memory impairment Hepatitis Jaundice Always give drug other anti-tubercle drug to prevent development of resistance Cheek for any effect.
- 48. SL NO . NAME OF DRUG TRA DE NAM E RO UTE DOSE MODE OF ACTION INDICA TION CONTRAIN DIRATION SIDE EFFECT NURSING RESPONSIBI LITIES 5 RIFAM PICIN - Oral/ IV 10-20 mg/kg Inhibit DNA dependent RNA polymerase impairs RNA synthesis Pulmon ary TB Hypersensiti vity Headache Fatigue Shock Drowsiness Hematuria Give drug atleast other anti TB drug for best absorption Monitor hepatic function Give capsule 1 hour before or 2 hrs after meal. Cheek for any side effect
- 50. SL NO . NAME OF DRUG TRA DE NAM E RO UTE DOSE MODE OF ACTION INDICAT ION CONTRAI NDIRATIO N SIDE EFFECT NURSING RESPONSIBI LITIES 1 ACYCL OVIR - Oral 10 mg/kg It inhibits the replication of virus It has a selective effect on the virus out affecting the host It is highly effective against reaps viruses Neonatal herpes simplex virus infection Herpes zoster virus infection Influenza virus infection . Hypersensi tivity Glaucoma Depression Pregnancy Lactation Penal impairment Headache Nausea Vomiting Skin rash Vaginitis Alopecia Muscle cramps Tremors Do not give 1m/se Monitor mental function Tell patient to take drug as prescribed Cheek for any side effect
- 51. SL NO . NAME OF DRUG TRA DE NAM E RO UTE DOSE MODE OF ACTION INDICATIO N CONTRAIN DIRATION SIDE EFFECT NURSING RESPONSIBI LITIES 2 RIBAVI RINE - Oral/ IV 5-10 mg/kg divided dose It is a purine nucleoside analogue It Is a broad spectrum of antiviral activity against DNA &RNA viruses. Infection viral infection respiratory tract viral infection influenza virus infection viral hepatitis herpes group of virus hypersensiti vity anemia renal impairment pregnancy lactation headache nausea vomiting skin rash cardiac arrest HTN Cheek vital sigins Follow 6 rights for administerin g the drug Monitor renal functions.
- 52. SL NO . NAME OF DRUG TRA DE NAM E RO UTE DOSE MODE OF ACTION INDICA TION CONTRAIN DIRATION SIDE EFFECT NURSING RESPONSIBI LITIES 3 ZIDOV UDINE - Oral/ IV 2mg/kg Nucleoside reverse transcriptase inhibit replication of HIV of blocking DNA synthesis HIV infectio n Hypersensiti vity Lactation Pregnancy Nausea Vomiting Diarrhea Skin rash Headache Monitor blood studies Cheek vital signs Instinct the patient to take drug is in cepty stomach
- 54. SL NO . NAME OF DRUG TRA DE NAM E RO UTE DOSE MODE OF ACTION INDICA TION CONTRAIN DIRATION SIDE EFFECT NURSING RESPONSIBI LITIES 1 ADREN ALIZE - IV/I M 0.2-0.5 ml for 6hrs This is a patient bronchodilator It also relieves the pulmonary congestion by constricts the pulmonary arterioles The relief of an attach of adrenalin is demotic but may be accompanied by unpleasant palpation It is helpful in smooth muscle relaxation. Beady cardio Beady arrhyth mias Hypersensiti vity Acute angle closure glaucoma Ischemia Obstructive neuropathy Angina Nausea Headache Vomiting Sweating Use extreme caution in alkylating & preparing doses Any education of adrenaline that is turn to pink should not be given BP should cheek every 15 minutes The drug should be injected slowly.
- 55. SL NO . NAME OF DRUG TRA DE NAM E RO UTE DOSE MODE OF ACTION INDICAT ION CONTRAIN DIRATION SIDE EFFECT NURSING RESPONSIBI LITIES 2 ATROPI NE SULHA TE - Oral/ IV se 0.02- 0.15 mg/kg Anti- cholinergic that inhibits acetyl choline as pares ympa their neuron affect or function Brady cardiac Brady are hythmias Hypersensiti vity Acute angle closure glaucoma Ischemia Obstructive uropathy Headache Insomnia Restlessness Palpitation Dey mouth Constipation Cheek for tacky cardiac Cheek vital signs Monitor I/O chart
- 56. SL NO . NAME OF DRUG TRA DE NAM E RO UTE DOSE MODE OF ACTION INDICA TION CONTRAIN DIRATION SIDE EFFECT NURSING RESPONSIBI LITIES 3 IPRATR OPIUM BROMI DE - Inhal ation 0.3% It inhibits reflux by antagonizing ACH muco curaine receptor on bronchial smooth muscle. Broncho spasm Rhinorr hea Hypersensiti ve Nausea Vomiting Blurred vision Palpitation Chest pain GI distress dyspnea take care to purulent leakage around the nose the drug should be injected slowly cheek for any side effects
- 57. SL NO . NAME OF DRUG TRA DE NAM E RO UTE DOSE MODE OF ACTION INDICA TION CONTRAIN DIRATION SIDE EFFECT NURSING RESPONSIBI LITIES 4 SALBU TAMOL - Oral 1mg/kg 6-8 hrs it is an odorless white powder it also relive the pulmonary congestion by constricts the pulmonary arterioles asthma emphys ema bronchit is myocardial insufficiency hyperthyroid ism pregnancy palpitation tremors tachycardia anorexia vomiting nausea cheek for any side effect monitor vital signs administer drug by follows 6 rights
- 58. CARDIOTONICS
- 59. SL NO . NAME OF DRUG TRA DE NAM E RO UTE DOSE MODE OF ACTION INDICA TION CONTRAIN DIRATION SIDE EFFECT NURSING RESPONSIBI LITIES 1 DIGOXI N - Orall y /IV 10- 15mg/k g 0.8- 1mg/kg for loyr children a cardiac glycoside that increases the influx of cat wine from extracellular to intracellular cytoplasm it is antiarrhythmic cardiac glycoside CHF Atrial fibrillat ion Paroxys m atrial achy cardiac Ventricular fibrillation Hypersensiti ve Ventricular tacky cardiac Acute MI Sinus beady cardiac Renal disease Hypothec disease Fatigue Headache Malaria Arrhythmia Anorexia Nausea Vomiting Diarrhea Do not administer rapidly by IV route to patient receiving diagnosis Instant patient do not take an extra dose of digoxin Advise patient to use some beand constantly
- 61. SL NO . NAME OF DRUG TRA DE NA ME ROU TE DOSE MODE OF ACTION INDICATIO N CONTRAI NDIRATIO N SIDE EFFECT NURSING RESPONSIBI LITIES 1 CYCL OPHO SPHA MIDE - 2-8 mg/ kg/ day Oral/IV An alkylating agent that inhibits DNA & RNA protein synthesis by crossing DNA & RNA strands It preventing cell growth. It is a potent immune suppressant Nephrotic syndrome Hodgkin’s disease Mycosis Fungoides Retinoblasto ma Breast carcinoma Ovarian adenocarci noma Hypersensi tivity Bone marrow suppresses Impaired renal/replica function Leukopenia Nausea Vomiting Alopecia Diarrhea Darkening of skin Stomatitis Headache Diaphoresis Monitoring CBC, differential, platelet count Renal function studies, BUN.UA, serum, uric acid Take the input output report.
- 62. SL NO . NAME OF DRUG TRA DE NA ME ROU TE DOSE MODE OF ACTION INDICATIO N CONTRAI NDIRATIO N SIDE EFFECT NURSING RESPONSIBI LITIES 2 VINCR ISTINE SULFA TE - IV 1.4-2 mg/day >10kg 50mg/k g for once weekly It exceeds it cytotoxic activity by assessing the cell lysis is the metap bone protein of cell division resulting cell lysis Also inhibits DNA dependent, RNA synthesis Hodgkin disease Neuronblast oma Willm’s tumor Hypersensi tivity Hepatic dysfunction Sensory loss Loss of deep tendon reflexes Diplopia Diarrhea Constipation Nausea Vomiting Anoxia Weight loss Encourage adequate fluid intake to increase urine output
- 63. SL NO . NAME OF DRUG TRA DE NA ME ROU TE DOSE MODE OF ACTION INDICATIO N CONTRAI NDIRATIO N SIDE EFFECT NURSING RESPONSIBI LITIES 3 METH OTRE XATE - Oral / IV 10-15 mg/day An anti metabolite that competes enzymes necessary to reduce folic acid to tetra hydro folic acid. It causes death of cancer cells. Trophoblasti c neoplasm Notify Head & neck cancer Chariot carcinoma Acute lymphocyti c leukemia Rheumatic arthritis Psoriasis Lymph sarcoma Hypersensi tivity Hepatic dysfunction Nausea Vomiting Stomatitis Burning Erythema Diarrhea Rash Dermatitis Provirus Dizziness Alopecia Anorexia Malaria Headache Blurred vission Provide patient fanuly education Notify clinician of black, chills, fever, sere throat, bleeding Diet 10-12 glasses of fluid/day Assess lives function tests
- 65. SL NO . NAME OF DRUG TRA DE NAM E RO UTE DOSE MODE OF ACTION INDICA TION CONTRAIN DIRATION SIDE EFFECT NURSING RESPONSIBI LITIES 1 INDIN AVIR SULFA TE Crixi van 500 mg Oral It prevents cleavage of the viral ply protein by bindings to the protease active site leading from action of immature non- infections viral particles. HIV infectio n Hypersensiti ve Sever hepatic impairment Headache Malaria Insomnia Dizziness Abdominal pain Nausea Vomiting Back pain Insect the patient to drink at least 1.5 L of fluid daily Inform the patient that indinavir is not a cure for HIV infection
- 66. SL NO . NAME OF DRUG TRA DE NAM E RO UTE DOSE MODE OF ACTION INDICA TION CONTRAIN DIRATION SIDE EFFECT NURSING RESPONSIBI LITIES 2 ZIDOV UDINE - 160 mg up to 200 mg/k g for neon ate Oral It will prevents the cleavage of the vital poly proteins by binding to the protease active site HIV infectio ns Hypersensiti ve Diarrhea Acid regulation Dry mouth Flank pain Severe headache Dizziness Convulsions Instruct the patient to drink at least 1.5 L of fluid daily
- 67. SL NO . NAME OF DRUG TRA DE NAM E RO UTE DOSE MODE OF ACTION INDICA TION CONTRAIN DIRATION SIDE EFFECT NURSING RESPONSIBI LITIES 3 AZIDOT HYMIDI NE - Oral/ IV 200-250 mg every 4- 8 hrs. It is synthetic analogue of thymidine It acts by inhibiting viral transcriptase It crosses placenta It decreases mortality HIV infectio n Hypersensiti vity Diarrhea Nausea Vomiting Dizziness Convulsions Instruct the patient to drink al least 1.5 L of fluid daily Cheek for side effects Monitor continuously