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DOC-20240314-WA0000..pptx Nyssa nuts hugj
- 25. Clinical Features
The clinical manifestations of hypocalcaemia result from
increased neuromuscular irritability.
Paraesthesia (tingling sensation) around mouth,
fingers and toes
Muscle cramps, carpopedal spasms
Tetany
Seizures – focal or generalised
Laryngospasm, stridor and apnoeas (neonates)
Cardiac rhythm disturbances (prolonged QT interval)
Chvostek’s and Trousseau’s signs – latent
hypocalcemia
25
- 44. Other Drugs In Addition To
Plantinum Agents
GI Losses
(Diarrhea,vomiting,malabsorpti
on)
Renal Wasting
Alcoholism
Malnutrition
Perform 24 Hrs Urine &Further
Testing As Apppropriate
Malabsorption
Vitmin D Deficiency
Hypophosphotenia
GI LOSSES
LOW DIETARY INTAKE
LOW SUNKIGHT EXPOSURE
REPLACE VITAMIN D
AUTOIMMUNE
GENETICS
POST SURGICAL
POST –RADIATION
INFILTRATIVE DISORDER
HIV