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1. Some of the remedies were prescribed by medical
doctors who treat pain and some recommendations
were from specialists like my primary care
physician who treated me at the time of my hospital
stay in 2001 who is a licensed M.D.D.O. And other
type of medical doctors such as herbalists,
traditionalists, homeopathic doctors (like me) and
even an Ortho Molecular doctor also has a part in
some of the nutritional remedies that are given in
this print.
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2.  Pharmacotherapy for the elderly can cure or
palliate disease as well as enhance health-related
quality of life (HRQOL). HRQOL considerations for
the elderly include focusing on improvement in
physical functioning, psychological functioning,
social functioning, and overall health. Despite the
benefits of pharmacotherapy, HRQOL can be
compromised by drug-related problems. The
avoidance of drug related adverse consequences in
the elderly requires health care practitioners to
become knowledgeable about a number of age-
specific issues.
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3.  In general, everything diminishes with age. Both
the pharmacodynamic as well as the
pharmacokinetic character changes with time.
With aging inherent variability in physiologic
differences becomes accentuated.
Pharmacodynamic responses are blunted, ability to
eliminate drugs is diminished and sensitivity to
the toxic effects of drugs is increased. The effects of
diseases are often additive and accumulate with
time. Disability and capacity for recuperation or
compensation are decreased. As a result the
incidence of adverse drug events is concentrated in
the elderly.
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4.  As a consequence of the age-related changes in body
composition, polar drugs that are mainly water-
soluble tend to have smaller volumes of distribution
(V) resulting in higher serum levels in older people.
Gentamicin, digoxin, ethanol, theophylline, and
cimetidine fall into this category. Loading doses of
digoxin need to be reduced to accommodate these
changes. On the other hand, nonpolar compounds
tend to be lipid-soluble and so their V increases with
age. The main effect of the increased V is a
prolongation of half-life. Increased V and t1/2 have
been observed for drugs such as diazepam,
thiopentone, lignocaine, and chlormethiazole.
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5.  Kate stated she was healthy until she went through
puberty. At first she developed severe acne at age 11,
which was treated with topical and oral medications (she
didn't know their names) for 2 years, after which she
began to develop asthma. She began oral medications
and inhalers for management of the asthma. Shortly
thereafter, when her periods began, she had a lot of
cramping and stomach discomfort. The doctor gave her
birth control pills, but after 6 months she stopped taking
them because she developed a blood clot in her right
lower calf requiring hospitalization and "blood thinning"
medication (Coumadin) for 6 months. Since that time,
there have been no recurrences of the blood clot.
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