The document discusses diabetes mellitus and its influence on pregnancy. It defines diabetes as a chronic disease resulting from insufficient insulin production. During pregnancy, diabetes can increase risks for both mother and fetus, such as abortion, preeclampsia, growth restriction, and neonatal complications. Gestational diabetes develops during pregnancy and usually resolves after delivery but increases later diabetes risk. The document outlines nursing interventions for gestational diabetes including glucose monitoring, dietary changes, exercise, education, and insulin administration if needed.
Fertilization or conception
Union of a sperm and a mature ovum
Takes place in outer third of the fallopian tube
Zygote
Initial name for fertilized ovum
Embryo
Name of product of conception from second through 8th week of pregnancy
Fetus
Name of the product of conception from 9th week through duration of gestational period
Fertilization or conception
Union of a sperm and a mature ovum
Takes place in outer third of the fallopian tube
Zygote
Initial name for fertilized ovum
Embryo
Name of product of conception from second through 8th week of pregnancy
Fetus
Name of the product of conception from 9th week through duration of gestational period
About Abortion | Where to find Abortion Pills Online?John Wharton
Abortion is a process to end the unwanted pregnancy. It can be done in two ways: Medical Abortion And Surgical Abortion.
Medical Abortion is a painless procedure. It is done privately and secretly. Get these Pills from the https://daynighthealthcare.com/
Mifeprex tablets each contain 200 mg of mifepristone, a synthetic steroid with anti progestational effects. The tablets are light yellow in color, cylindrical and biconvex, and are intended for oral administration only. The tablets include the inactive ingredients colloidal silica anhydrous, corn starch, povidone, microcrystalline cellulose, and magnesium stearate.
Indications and Outcomes of Emergency Caesarean Section at St Paul’s Hospital...Crimsonpublishers-IGRWH
Indications and Outcomes of Emergency Caesarean Section at St Paul’s HospitalMedical College, Addis Ababa, Ethiopia 2017: (Afoul Month Retrospective Cohort Study) by Bizuneh Ayano in Womens Health Journal
Abortion is the ending of pregnancy by removing an embryo or fetus before it can survive outside the uterus. An abortion that occurs spontaneously is also known as a miscarriage.
Abortion pills preferred over surgical abortion for safetyAnna Ray
Abortion pills are the safest and highly recommended medical way of abortion extensively employed in the execution of an abortion to end an early pregnancy of 7 to 9 weeks of gestation. Abortion pills are the highly appraised medial way for abortion for women who are willing to annihilate their pregnancy in a safe and successful way without any complication. Mifepristone and Misoprostol are the two counteractive moieties present in Abortion pills. Visit: http://www.abortionpill24.net/buy-abortion-pills-mifepristone-and-misoprostol-online.html
Threatened abortion by dr alka mukherjee dr apurva mukherjee nagpur m.s.alka mukherjee
Threatened abortion is associated with bleeding and/or uterine cramping while the cervix is closed. This stage of abortion may progress to spontaneous incomplete or complete abortion. While this event may be considered a part of the quality control process in human reproduction, it is important to know the possible etiologies and when therapy might prevent pregnancy loss. The World Health Organization estimated that 15% of all clinically recognizable pregnancies and in spontaneous abortion, 50-60% of which are due to chromosomal abnormalities. Apart from the fetal factors, several maternal and probably paternal factors contribute to the causes of spontaneous abortion. The maternal factors that may be responsible for abortion include both local and systemic conditions such as infections, maternal disease states, genital tract abnormalities, endocrine factors and other miscellaneous causes (antiphospholipid antibodies, maternal-fetal histocompatibility, excessive smoking and other environmental toxicants, etc.). This review focuses on the management of threatened abortion, but it should be emphasized that the management to maintain pregnancy is reasonable only in those cases, in which the fetus is not seriously affected. It would not be beneficial to provide treatment that would permit chromosomally and anatomically abnormal embryos to survive to term. Treatment is feasible first of all in cases with maternal factors. Surgical procedures may precede pregnancy (correction of septate uterus, removal of a submucous leiomyomata) or may be performed usually in the second trimester (cervical cerclage). Maternal general diseases (diabetes, hypothyroidism) and infections should be treated accordingly. The most common entity to be treated in this category is luteal phase deficiency. Progesterone is the most important hormone for the maintenance of an early human pregnancy. Besides progesterone administration, human chorionic gonadotropin (hCG) also is the logical endocrine treatment of choice. In the pregnant woman hCG stimulates and optimizes hormonal production in the corpus luteum and may also influence the fetoplacental unit. The contribution of environmental, physical and chemical agents to the incidence of spontaneous abortion is controversial. They may be abortifacient even if they are not teratogenic. Exposure to environmental toxicants should be avoided. Paternal leukocyte immunotherapy has been associated with successful outcome in patients with unexplained repeated spontaneous abortion. This therapeutic approach is considered experimental, as there may be some significant risks. Associating maternal antiphospholipid antibodies with reproductive failure is a rapidly developing field. Administration of corticosteroids with low doses of aspirin has resulted in fetal salvage in women in whom antiphospholipid antibodies are present.
A miscarriage is the loss of pregnancy from natural causes before the 20th week of pregnancy. Most miscarriages occur very early in the pregnancy, often before a woman even knows she is pregnant. There are many different causes for a miscarriage. In most cases, there is nothing you can do to prevent a miscarriage.
About Abortion | Where to find Abortion Pills Online?John Wharton
Abortion is a process to end the unwanted pregnancy. It can be done in two ways: Medical Abortion And Surgical Abortion.
Medical Abortion is a painless procedure. It is done privately and secretly. Get these Pills from the https://daynighthealthcare.com/
Mifeprex tablets each contain 200 mg of mifepristone, a synthetic steroid with anti progestational effects. The tablets are light yellow in color, cylindrical and biconvex, and are intended for oral administration only. The tablets include the inactive ingredients colloidal silica anhydrous, corn starch, povidone, microcrystalline cellulose, and magnesium stearate.
Indications and Outcomes of Emergency Caesarean Section at St Paul’s Hospital...Crimsonpublishers-IGRWH
Indications and Outcomes of Emergency Caesarean Section at St Paul’s HospitalMedical College, Addis Ababa, Ethiopia 2017: (Afoul Month Retrospective Cohort Study) by Bizuneh Ayano in Womens Health Journal
Abortion is the ending of pregnancy by removing an embryo or fetus before it can survive outside the uterus. An abortion that occurs spontaneously is also known as a miscarriage.
Abortion pills preferred over surgical abortion for safetyAnna Ray
Abortion pills are the safest and highly recommended medical way of abortion extensively employed in the execution of an abortion to end an early pregnancy of 7 to 9 weeks of gestation. Abortion pills are the highly appraised medial way for abortion for women who are willing to annihilate their pregnancy in a safe and successful way without any complication. Mifepristone and Misoprostol are the two counteractive moieties present in Abortion pills. Visit: http://www.abortionpill24.net/buy-abortion-pills-mifepristone-and-misoprostol-online.html
Threatened abortion by dr alka mukherjee dr apurva mukherjee nagpur m.s.alka mukherjee
Threatened abortion is associated with bleeding and/or uterine cramping while the cervix is closed. This stage of abortion may progress to spontaneous incomplete or complete abortion. While this event may be considered a part of the quality control process in human reproduction, it is important to know the possible etiologies and when therapy might prevent pregnancy loss. The World Health Organization estimated that 15% of all clinically recognizable pregnancies and in spontaneous abortion, 50-60% of which are due to chromosomal abnormalities. Apart from the fetal factors, several maternal and probably paternal factors contribute to the causes of spontaneous abortion. The maternal factors that may be responsible for abortion include both local and systemic conditions such as infections, maternal disease states, genital tract abnormalities, endocrine factors and other miscellaneous causes (antiphospholipid antibodies, maternal-fetal histocompatibility, excessive smoking and other environmental toxicants, etc.). This review focuses on the management of threatened abortion, but it should be emphasized that the management to maintain pregnancy is reasonable only in those cases, in which the fetus is not seriously affected. It would not be beneficial to provide treatment that would permit chromosomally and anatomically abnormal embryos to survive to term. Treatment is feasible first of all in cases with maternal factors. Surgical procedures may precede pregnancy (correction of septate uterus, removal of a submucous leiomyomata) or may be performed usually in the second trimester (cervical cerclage). Maternal general diseases (diabetes, hypothyroidism) and infections should be treated accordingly. The most common entity to be treated in this category is luteal phase deficiency. Progesterone is the most important hormone for the maintenance of an early human pregnancy. Besides progesterone administration, human chorionic gonadotropin (hCG) also is the logical endocrine treatment of choice. In the pregnant woman hCG stimulates and optimizes hormonal production in the corpus luteum and may also influence the fetoplacental unit. The contribution of environmental, physical and chemical agents to the incidence of spontaneous abortion is controversial. They may be abortifacient even if they are not teratogenic. Exposure to environmental toxicants should be avoided. Paternal leukocyte immunotherapy has been associated with successful outcome in patients with unexplained repeated spontaneous abortion. This therapeutic approach is considered experimental, as there may be some significant risks. Associating maternal antiphospholipid antibodies with reproductive failure is a rapidly developing field. Administration of corticosteroids with low doses of aspirin has resulted in fetal salvage in women in whom antiphospholipid antibodies are present.
A miscarriage is the loss of pregnancy from natural causes before the 20th week of pregnancy. Most miscarriages occur very early in the pregnancy, often before a woman even knows she is pregnant. There are many different causes for a miscarriage. In most cases, there is nothing you can do to prevent a miscarriage.
Our aim is to alleviate human suffering related to diabetes and its complications among those least able to withstand the burden of the disease. From 2002 to March 2017, the World Diabetes Foundation provided USD 130 million in funding to 511 projects in 115 countries. For every dollar spent, the Foundation raises approximately 2 dollars in cash or as in-kind donations from other sources. The total value of the WDF project portfolio reached USD 377 million, excluding WDF’s own advocacy and strategic platforms.
This presentation deals with information regarding a minor disorder of pregnancy i.e hyperemesis gravidarum, its manifestations, causes, diagnostic evaluation,complications, management, nursing interventions etc.Though its a minor disorder, delayed treatment can be fatal.
The GDG stresses that the four-visit focused ANC (FANC) model does not offer women adequate contact with health-care practitioners and is no longer recommended. With the FANC model, the first ANC visit occurs before 12 weeks of pregnancy, the second around 26 weeks, the third around 32 weeks, and the fourth between 36 and 38 weeks of gestation
Definition
Incidence
Types
Diabetogenic effect of pregnancy
Metabolic changes during pregnancy
Risk of uncontrolled DM on pregnancy
Diagnosis and evaluation
Medical management
Nursing management
Definition of Diabetes mellitus:It is inability to metabolize glucose properly. It is a chronic systemic disease, manifesting metabolic and vascular changes affecting every organ in the body.
a. Pregestational (preexisting) diabetes
Occurs when have type 1 or type 2 diabetes before becoming pregnant.
1-Type I Insulin-dependent (IDDM) (Insulin deficient).
2-Type II Non-Insulin dependent (NIDDM) (Insulin resistant).
b. Gestational diabetes mellitus (GDM).
Occurs diabetes when becoming pregnant.
a. Pregestational (preexisting) diabetes
Occurs when have type 1 or type 2 diabetes before becoming pregnant.
1-Type I Insulin-dependent (IDDM) (Insulin deficient).
2-Type II Non-Insulin dependent (NIDDM) (Insulin resistant).
b. Gestational diabetes mellitus (GDM).
Occurs diabetes when becoming pregnant.
Diabetes may appear only during pregnancy due to :-
1-Increased levels of antiinsulinas (estrogen, progesteron, human placental lactogen, and prolactine).
2-Decreased renal threshold for glucose (glucose loss in urine).
During early stage of pregnancy: Maternal hypoglycemia.
After the fourth month: increase glucose level in the blood due to placental hormones
During labor: liability to hypoglycaemia.
After delivery: glucose level return to prepregnant state.
Gestational Diabetes
Risk Factors
Maternal age >25
Family history
Glucosuria
Prior macrosomia
Previous unexplained stillbirth
Risk of uncontrolled diabetes on pregnancy
A- Maternal effect:
On pregnancy On labor On puerperium
-Abortion - premature -puerperal sepsis
-PET labor -PPH
-Polyhydramnios - Inertia - Abnormal
-Pressure symptom - Operative lactation
-Infection delivery
-Retinopathy
Risk of uncontrolled diabetes on fetus
1- Abortion
2- Congenital anomalies
Open neural defect, CHD, renal anomaly, sacral agenesis, small left colon syndrome(Approximately 40% to
50% of infants with this disorder have diabetic mothers, almost all of whom are insulin dependent , , imperforated anus.
3- Macrosomia
Fetal hyperglycaemia causes increase insulin secretion and lead to increase fetal fat deposition
Open neural defect
sacral agenesis
Macrosomia
Macrosomia
Macrosomia
Risk of uncontrolled diabetes on fetus
4- Intrauterine fetal death due to:
Congenital malformation, ketoacedosis, hypoglycaemia, superimposed PET.
5- Neonatal hypoglycemia
After delivery, glucose concentration fail, while neonatal insulin level remain high lead to neonatal hypoglycemia (Tremors, pallor, apnea, cyanosis)
Risk of uncontrolled diabetes on fetus
7- Hyperbilirubinaemia
Due to immature liver
8- Neonatal death due to:
Congenital anomalies
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
3. 3
• Chairman of obstetrics &woman health
nursing department
• Pre. Vice dean for students &Education
Affair
Thursday, April 5, 2018Dr. Soad Abd El salam Ramdan
5. Diabetes Mellitus
Definition
• Diabetes mellitus is a chronic disease resulting from a relative or
absolute lack of insulin, which is required for carbohydrate metabolism.
• In diabetes mellitus, the pancreas does not produce sufficient amounts of
insulin to allow necessary carbohydrate metabolism.
• With inadequate amounts of insulin, glucose cannot enter the cells and
remains in the blood.
Thursday, April 5, 2018Dr. Soad Abd El salam Ramdan5
6. Etiology
Insulin deficiency may be caused by:
◘ Damage to beta cells in the pancreas.
◘ Increased insulin ruirement as in obesity
and pregnancy.
Thursday, April 5, 2018Dr. Soad Abd El salam Ramdan6
7. •Mother with family history of diabetes and
hypertension
•Obesity
•Polyhydrominos.
•Mother over 45 years of age and less than 20years.
•Multiparty .
•Repeated unexplained abortion or still birth.
•Previous macrocosmic infant.
Risk factors for gestational diabetes:
Thursday, April 5, 2018Dr. Soad Abd El salam Ramdan7
8. Influence of Diabetes on Pregnancy
Outcome:-
1-Maternal :-
Increased incidence of abortion
Increased incidence of preeclampsia
Increased incidence of prenatal mortality and
morbidity
Preterm labor
Polyhydrominos
Infection
Incidence of cesarean section.
Thursday, April 5, 2018Dr. Soad Abd El salam Ramdan8
9. 2- Fetal and Neonatal :
• Hypoglycemia or hyperglycemias
• Intrauterine growth restriction
• Intrauterine fetal death.
• Fetal congenital malformation
• Neonatal hyperbilirubinemia
• Macrosomia
• Prematurity and RDS.
Thursday, April 5, 2018Dr. Soad Abd El salam Ramdan9
10. Thursday, April 5, 2018Dr. Soad Abd El salam Ramdan
Cont.
During labor:
Mother:
► Obstructed labor.
► Incidence of cesarean
section.
Fetus:
► Prematurity.
► Neonatal hypoglycemia.
► Respiratory distress.
► Macrosomia.
10
11. Thursday, April 5, 2018Dr. Soad Abd El salam Ramdan11
Postpartum:
• Postpartum hemorrhage
• . Infection.
12. Thursday, April 5, 2018Dr. Soad Abd El salam Ramdan
Symptoms of Diabetes Mellitus
•Excessive thirst and hunger.
•Frequent urination.
•Blurred vision.
•Weight loss.
•Recurrent infections
12
13. Gestational Diabetes Mellitus (GDM):
•Onset of symptoms occurs
during pregnancy.
•Usually disappears after
delivery.
•Women with GDM are at
risk for developing DM at a
later date.
Symptoms of Diabetes
Mellitus
• ◘ Excessive thirst and
hunger.
• ◘ Frequent urination.
• ◘ Blurred vision.
• ◘ Weight loss.
• ◘ Recurrent infections.
Thursday, April 5, 2018Dr. Soad Abd El salam Ramdan13
16. Oral Glucose Tolerance Test
(OGTT)
Thursday, April 5, 2018Dr. Soad Abd El salam Ramdan16
17. Thursday, April 5, 2018Dr. Soad Abd El salam Ramdan
Nursing Intervention for Gestational Diabetes
• Controlling serum glucose
• Dietary adjustment
• Insulin:
• Prevent, recognize and treat hypo- or hyperglycemia
• Ultrasound assessment at 20 week of gestation.
• Educate the patient regarding self-care measures:
• Activity and exercise:
• Hospitalization:
►From 32 week till delivery for patient with vascular changes.
17
18. Teach pt. to estabilish and maintain a pattern of regular exercise &
Benefits of exercise :
• promotes use of CHO & enhances action of insulin
• blood glucose levels
• need for insulin
➢ perform exercise after meals to ensure an adequate level of blood
glucose
➢ carry a rapid-acting source of glucose during exercise
➢ excessive or unplanned exercise may trigger hypoglycemia
➢ take insulin and food before active exercise
Thursday, April 5, 2018Dr. Soad Abd El salam Ramdan18
19. Teach pt. to practice good personal hygiene and positive health
promotion to avoid diabetic complications:-
1. Teach pt. about diabetic foot care
▪ continue taking insulin or oral hypoglycemic agents
▪ maintain fluid intake
▪ frequency of blood testing or urine testing
2. help pt. identify stressful situations in lifestyle that might
interfere with good diabetic control
3. encourage good daily hygiene
4. advise regular eye exams
5. Teach aggressive care for minor skin cuts
Thursday, April 5, 2018Dr. Soad Abd El salam Ramdan19