Diabetes 2
•Download as PPT, PDF•
0 likes•719 views
This document summarizes key information about type 2 diabetes drug candidates in phase 3 clinical trials, including their mechanisms of action and endpoints. Five major drugs are discussed: BMS-512148, Victoza, D-Tagatose, JNJ-28431754, and Albiglutide. BMS-512148 and JNJ-28431754 are SGLT2 inhibitors, Victoza is a GLP-1 receptor agonist, D-Tagatose blocks glucose absorption, and Albiglutide is a GLP-1 agonist fused to human albumin for extended effects. The average trial duration is 2.5 years and endpoints include HbA1c, weight, and
Report
Share
Report
Share
![[object Object],[object Object],[object Object],[object Object],[object Object],Outline](data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7)
Recommended
Type 2 diabetes - A 2016 update by Zeena Nackerdien
This document discusses key aspects of type 2 diabetes treatment including goals, approach, and pharmacologic agents. The main goals are to reduce cardiovascular risk factors and achieve individualized glycemic targets to minimize complications. The recommended treatment approach is lifestyle changes and metformin as initial therapy, followed by adding other agents if needed. Agents that are preferentially recommended have a low risk of hypoglycemia and weight gain. Incretin-based therapies such as GLP-1 receptor agonists and DPP-4 inhibitors are important non-insulin options. Insulin therapy may be needed to intensify treatment for patients not achieving goals.
Ueda 2016 3-glycemic targets & monitoring- adel el sayed
This document provides information on glycemic targets and monitoring for diabetes. It discusses recommended HbA1c targets of below 7% to minimize complications, and reviewing targets regularly based on safety and benefits. Self-monitoring of blood glucose (SMBG) is recommended for those on insulin and may be optional for some on oral medications. Symptoms and treatment of hypoglycemia are covered, including increasing risk with intensive control. Managing hypoglycemia unawareness and rebound hyperglycemia are also addressed.
Type 2 diabetes mellitus
Type 2 diabetes is characterized by hyperglycemia due to insulin resistance and relative insulin deficiency. It is a chronic disease with a high and growing global prevalence, particularly in urban and high-income areas. Key risk factors include lack of exercise and obesity. Common symptoms include increased urination, thirst, and weight loss. Diagnosis involves tests such as HbA1c, fasting blood glucose, and oral glucose tolerance test. Treatment focuses on medications like metformin and lifestyle changes involving diet and exercise to manage blood sugar levels and prevent complications like renal failure.
Diabetes ppt
Prediabetes is a stage where blood glucose levels are higher than normal but not high enough to be considered diabetes, and it affects 79 million Americans who are already experiencing damage to their bodies, especially the heart and circulatory system. Type 1 diabetes is usually diagnosed in children and young adults where the pancreas does not produce insulin. Type 2 diabetes is the most common form where the body does not produce enough insulin or cells ignore the insulin, and it often affects African Americans, Latinos, Asian Americans and Native Americans. Gestational diabetes develops during pregnancy for 3-8% of women and increases their risk of later developing Type 2 diabetes.
Global report diabetes
Diabetes is a serious, chronic disease that occurs either when the pancreas does not produce enough insulin (a hormone that regulates blood glucose), or when the body cannot effectively use the insulin it produces (1). Raised blood glucose, a common effect of uncontrolled diabetes, may, over time, lead to serious damage to the heart, blood vessels, eyes, kidneys and nerves. More than 400 million people live with diabetes.
updates in management of Diabetes mellitus
Diabetes is a worldwide disease .Many anti diabetic drugs play a role in hypoglycemic control with a different mechanism of action
Final control diabetes keep up to date 10 march 2016
Oral antidiabetic drugs contains SUs,metformin, glinides ,ddp-4 inhibitors,incretin mimietics liraglutide &exenatide And SGLT-2
Glp1 clinical view
- GLP-1 receptor agonists are recommended as first-line treatment after metformin for type 2 diabetes due to their ability to reduce weight and cardiovascular risk factors like lipids and blood pressure while improving glycemic control with a low risk of hypoglycemia. Early initiation of GLP-1 agonists may help preserve beta-cell function by reducing glucotoxicity and increasing beta-cell mass. Exenatide was the first incretin mimetic and works similarly to natural GLP-1 but is resistant to degradation, allowing twice-daily dosing. Newer long-acting GLP-1 agonists only require once weekly or daily dosing. Nausea is a common side effect but usually mild and intermittent
Recommended
Type 2 diabetes - A 2016 update by Zeena Nackerdien
This document discusses key aspects of type 2 diabetes treatment including goals, approach, and pharmacologic agents. The main goals are to reduce cardiovascular risk factors and achieve individualized glycemic targets to minimize complications. The recommended treatment approach is lifestyle changes and metformin as initial therapy, followed by adding other agents if needed. Agents that are preferentially recommended have a low risk of hypoglycemia and weight gain. Incretin-based therapies such as GLP-1 receptor agonists and DPP-4 inhibitors are important non-insulin options. Insulin therapy may be needed to intensify treatment for patients not achieving goals.
Ueda 2016 3-glycemic targets & monitoring- adel el sayed
This document provides information on glycemic targets and monitoring for diabetes. It discusses recommended HbA1c targets of below 7% to minimize complications, and reviewing targets regularly based on safety and benefits. Self-monitoring of blood glucose (SMBG) is recommended for those on insulin and may be optional for some on oral medications. Symptoms and treatment of hypoglycemia are covered, including increasing risk with intensive control. Managing hypoglycemia unawareness and rebound hyperglycemia are also addressed.
Type 2 diabetes mellitus
Type 2 diabetes is characterized by hyperglycemia due to insulin resistance and relative insulin deficiency. It is a chronic disease with a high and growing global prevalence, particularly in urban and high-income areas. Key risk factors include lack of exercise and obesity. Common symptoms include increased urination, thirst, and weight loss. Diagnosis involves tests such as HbA1c, fasting blood glucose, and oral glucose tolerance test. Treatment focuses on medications like metformin and lifestyle changes involving diet and exercise to manage blood sugar levels and prevent complications like renal failure.
Diabetes ppt
Prediabetes is a stage where blood glucose levels are higher than normal but not high enough to be considered diabetes, and it affects 79 million Americans who are already experiencing damage to their bodies, especially the heart and circulatory system. Type 1 diabetes is usually diagnosed in children and young adults where the pancreas does not produce insulin. Type 2 diabetes is the most common form where the body does not produce enough insulin or cells ignore the insulin, and it often affects African Americans, Latinos, Asian Americans and Native Americans. Gestational diabetes develops during pregnancy for 3-8% of women and increases their risk of later developing Type 2 diabetes.
Global report diabetes
Diabetes is a serious, chronic disease that occurs either when the pancreas does not produce enough insulin (a hormone that regulates blood glucose), or when the body cannot effectively use the insulin it produces (1). Raised blood glucose, a common effect of uncontrolled diabetes, may, over time, lead to serious damage to the heart, blood vessels, eyes, kidneys and nerves. More than 400 million people live with diabetes.
updates in management of Diabetes mellitus
Diabetes is a worldwide disease .Many anti diabetic drugs play a role in hypoglycemic control with a different mechanism of action
Final control diabetes keep up to date 10 march 2016
Oral antidiabetic drugs contains SUs,metformin, glinides ,ddp-4 inhibitors,incretin mimietics liraglutide &exenatide And SGLT-2
Glp1 clinical view
- GLP-1 receptor agonists are recommended as first-line treatment after metformin for type 2 diabetes due to their ability to reduce weight and cardiovascular risk factors like lipids and blood pressure while improving glycemic control with a low risk of hypoglycemia. Early initiation of GLP-1 agonists may help preserve beta-cell function by reducing glucotoxicity and increasing beta-cell mass. Exenatide was the first incretin mimetic and works similarly to natural GLP-1 but is resistant to degradation, allowing twice-daily dosing. Newer long-acting GLP-1 agonists only require once weekly or daily dosing. Nausea is a common side effect but usually mild and intermittent
Ueda2016 symposium - pathophysiology of diabetes - abbas orabi
The document discusses pathophysiology of diabetes and treatment strategies. It summarizes that multiple defects contribute to type 2 diabetes progression, including beta-cell dysfunction from lipotoxicity, glucotoxicity, amyloid deposition, and genetics. The kidney plays an important role in glucose homeostasis by reabsorbing the majority of filtered glucose via SGLT2 transporters in the proximal tubule. In diabetes, the renal threshold for glucose is increased, allowing more glucose reabsorption and higher plasma levels. SGLT2 inhibitors lower this threshold, inducing glucosuria and reducing hyperglycemia. Clinical trials showed canagliflozin improved HbA1c and weight compared to sitagliptin when added to metformin, demonstrating its
New treatment for Diabetes Mellitus and Drugs to treat Hypoglycemia
This ppt covers recently FDA approved treatment of DM and other drugs that are in clinical pipelines or still under consideration. 2nd portion of ppt covers protocol used to treat hypoglycemia in different situations.
Ueda2016 do we know what is type 2 -assem zeyada
This document discusses type 2 diabetes, including its definition, pathogenesis, and current state of understanding. It defines type 2 diabetes as a group of metabolic disorders characterized by hyperglycemia due to defects in both insulin secretion and action. The document notes that type 2 diabetes is increasing worldwide and can now affect adolescents. It discusses the genetic and environmental factors involved in its pathogenesis, including islet cell defects and insulin resistance in tissues. While lifestyle changes and current pharmacotherapies can help manage the disease, the document concludes that the underlying mechanisms remain poorly understood and that type 2 diabetes continues to represent a major global health challenge.
Diabetes mellitus
This document discusses diabetes, including its definition, types, symptoms, management, and statistics. Some key points include:
- Diabetes is a metabolic disorder characterized by high blood glucose caused by insufficient insulin production or action.
- Over 25 million Americans have diabetes, and it is projected to affect over 333 million people worldwide by 2025, with 90% having type 2 diabetes.
- There are two main types of diabetes - type 1 is usually diagnosed in childhood and requires insulin injections, while type 2 usually occurs in adulthood and can sometimes be managed through diet and exercise.
- Symptoms vary depending on type but include increased urination, thirst, fatigue, and weight changes. Proper management is important to prevent
Dm
Diabetes mellitus is a chronic disease characterized by high blood glucose levels due to either the body not producing enough insulin or cells not responding properly to insulin. There are different types of diabetes classified by the WHO including type 1, type 2, gestational diabetes and others. The document discusses the causes, risk factors, clinical manifestations, complications and management of diabetes as well as prevention strategies and the national diabetes control program in India.
Ueda2016 workshop - hypoglycemia1 -lobna el toony
This document discusses hypoglycemia in diabetes. It defines hypoglycemia and describes its prevalence, causes, and risk factors. It notes that hypoglycemia is more common in type 1 diabetes and with intensive diabetes control. The document outlines the symptoms of mild, moderate, and severe hypoglycemia and explains how the body normally protects against low blood sugar. However, in diabetes these protective mechanisms become impaired over time, increasing the risk of severe hypoglycemia. The document discusses hypoglycemia in the context of type 1 and type 2 diabetes and provides tips for prevention and management, including recognizing risk factors, treating the underlying cause, and adjusting medications and food intake. It focuses on strategies to prevent nocturnal hypoglycemia specifically
Clinical aspects of diabetes prof alaa wafa
This document provides information on the diagnosis and management of diabetes mellitus. It begins with definitions of diabetes and descriptions of its various types. Type 1 diabetes is characterized by an autoimmune destruction of beta cells resulting in insulin deficiency, while type 2 diabetes involves insulin resistance and usually affects older individuals. Gestational diabetes occurs during pregnancy. The core defects of type 2 diabetes include insulin resistance and insulin deficiency. Lifestyle modifications and various classes of glucose-lowering medications are used to manage diabetes, with the treatment approach individualized based on each patient's case.
Kouaka diabetes ptt (2)
The document provides information about a presentation on diabetes. It will define diabetes, its causes, symptoms, and how to manage the disease. Attendees will learn to determine if they have diabetes, control blood sugar levels, and identify types 1, 2, and 3 diabetes. The presentation covers symptoms, testing blood sugar levels, diet, exercise, medications, and the importance of eating well and exercising regularly to prevent and control diabetes.
A Retrospective Study of Clinical and Biochemical Profile in Geriatric Patien...
The aim of the study was to evaluate the clinical and
biochemical characteristics of geriatric patients with type 2
diabetes mellitus (DM) attending tertiary care teaching hospital,
SVIMS, Tirupati. OBJECTIVES: To document clinical
features, biochemical parameters and anti-diabetic medications
received as per records. METHODOLOGY: This
retrospective study was performed in Department of
Endocrinology in SVIMS, Tirupati, over a period of 6 months.
Demograghic details, laboratory parameters and
pharmacotherapy details were collected in the pre-designed
annexure form. RESULTS: A total of 100 diabetic elderly
patients were included in the study. Out of which 57 were men,
43 were women. Most of them were under the age group of
60-64 years followed by other age groups. 28 patients were
having the diabetes duration of 11-15 years. Some of them were
having diabetic complications (such as diabetic retinopathy,
diabetic neuropathy, diabetic nephropathy). Among 100
patients, 32 patients were normal weight, 22 patients were
overweight, 28 patients were obese-I, 18 patients were obese-II.
About 85% of patients were having high lipid levels. Some
patients were on Oral Hypoglycemic Agents (OHAS), some
patients were using both Insulin & OHAS.CONCLUSION:
The present study comprised of 100 elderly type 2 diabetic
patients in which males were higher in number when compared
to females, most of the patients were in the age of group of
60-64 years. Hypertension was the most common co-morbidity
associated with DM followed by Coronary Artery Disease
(CAD). Diabetic neuropathy was the most prevalent
complication followed by Diabetic retinopathy and diabetic
nephropathy. In this study 46% of the patients were obese. Most
of the patients were on OHAS alone, some were on OHAS and
Insulin combination therapy while very few were on insulin
therapy alone. Dyslipidemia was present in 85% of the patients
and the most common form of dyslipidemia was low HDL and
high LD
Ueda2016 symposium - management of type 2 dm overcoming the challenges - mes...
This document provides guidance on the management of type 2 diabetes mellitus (T2DM). It discusses factors to consider when choosing oral antidiabetic drugs (OADs), including efficacy, safety, effect on weight and comorbidities. Dipeptidyl peptidase-4 (DPP-4) inhibitors like linagliptin are recommended as part of dual or triple therapy if HbA1c targets are not met with other agents. Linagliptin has advantages over other DPP-4 inhibitors in that it is primarily excreted unchanged in bile and does not require dose adjustment in patients with renal impairment. The document provides treatment algorithms for achieving glycemic control in T2DM
Diabetes mellitus part-1
This document provides information on diabetes mellitus (DM), including its classification, differences between type 1 and type 2 DM, etiology, pathophysiology, and genetics. It discusses that DM is classified based on the pathogenic process causing hyperglycemia into type 1 and type 2. Type 1 DM results from beta cell destruction leading to insulin deficiency, while type 2 DM ranges from insulin resistance with relative deficiency to a secretory defect with resistance. The document outlines the etiology and pathophysiology of both types of DM in detail. It also addresses the genetic considerations for type 1 DM.
Diabetes Mellitus
Diabetes mellitus is a metabolic disorder characterized by high blood glucose levels due to either lack of insulin production or resistance to insulin. It ranges from asymptomatic to causing severe health issues like cardiovascular disease if uncontrolled. Risk factors include genetics, obesity, physical inactivity, and diet. Prevention strategies involve education, screening high risk groups, early treatment, and ongoing management of the condition and related health factors.
THE NUTRITION THERAPY IN DIABETIC PATIENTS: A REVIEW
Diabetes Mellitus is one of the leading metabolic disorders in the world with many complications. The
management of Diabetes Mellitus can prevent many chronic diseases like stroke, myocardial infarction, diabetic
nephropathy, neuropathy and obesity. An appropriate dietary changes and lifestyle changes have proven to be
effective in the preventing and management of this disorder.Medical nutrition therapy (MNT) is an essential
component of diabetes management that comprises counseling and recommendations for dietary intake and nutrition
goals by a registered dietician (RD) or a nutrition expert to optimize metabolic control and maximize treatment
outcomes. The designing of the diet according to the nutrional needs of an individual and regular monitoring by a
dietician can provide effective results in the management. The counseling with the patient provides the detailed
information about the diet and the modifications in the diet can be made according to the age, weight, glucose level
and physical activity. The desired goal of the blood pressure, blood glucose, triglycerides can be achieved by
following the diet plan.
Type 2 Diabetes and Genes
Genes play a significant role in determining risk of developing type 2 diabetes. Having one or both parents with the condition increases risk by 15-75%, while identical twins show a 90% concordance rate. Several genes have been identified that may contribute to diabetes through effects on insulin secretion, action, fat metabolism and storage. However, environmental factors like diet and lifestyle are also important, as adoption of a Western lifestyle can increase risk even in populations that were previously low-risk. Both genes and environment interact to promote conditions like insulin resistance through their combined effects on cells and metabolism.
Management and prevention of T2DM and Hypertension
This document provides information from a presentation on preventing and managing diabetes complications. It includes:
1) Guidelines for hypertension treatment in diabetics, including a blood pressure goal of <140/90 mmHg and the recommendation that treatment includes an ACE inhibitor or ARB.
2) Evidence from the ACCORD trial showing no additional benefit of intensive blood pressure control (<120 mmHg) over standard control (<140 mmHg) for cardiovascular outcomes in diabetics. Intensive control did increase adverse events.
3) Recommendations for treating nephropathy in diabetics with an ACE inhibitor or ARB for those with modest or higher albuminuria levels.
Dm & liver
This document discusses the management of diabetes in patients with concomitant liver disease. It notes that about half of patients with cirrhosis have diabetes due to insulin resistance caused by the liver disease. Lifestyle changes and metformin are recommended initially if liver disease is mild. Insulin, sulfonylureas, meglitinides, alpha-glucosidase inhibitors, and thiazolidinediones may be used, with monitoring needed due to potential side effects or altered drug metabolism in liver disease. Insulin requirements can vary depending on the stage of liver disease.
Diabetes 1
This document provides information about diabetes mellitus. It defines diabetes as a group of metabolic diseases characterized by high blood glucose levels due to defects in insulin secretion or action. The main types of diabetes are described as type 1, type 2, and gestational diabetes. Symptoms, diagnostic criteria, risk factors, and management strategies like nutrition, exercise, medication and insulin therapy are discussed for each type. The goals of diabetes management are to control blood glucose levels through diet, exercise, oral hypoglycemic drugs, and insulin in order to prevent long-term health complications.
Cme ppt final with images
The document discusses caring for people with diabetes by providing an overview of the disease. It covers understanding diabetes, types of diabetes, common symptoms, diagnosing diabetes through blood glucose testing, dangers of high blood glucose levels over time including damage to blood vessels and nerves, goals of treatment, the four pillars of diabetes management including diet, exercise, self-monitoring of blood glucose, and pharmacological treatment including oral medications and insulin therapy. It also addresses potential complications such as hypoglycemia and how to treat low blood sugar.
Role of early basal insulin initiation of t2 dm
1) The document discusses guidelines for initiating basal insulin therapy in patients with type 2 diabetes, including benefits such as lowering HbA1c and reducing cardiovascular risk.
2) It compares different basal insulin options like glargine, detemir, and NPH insulin, finding that the long-acting analogs glargine and detemir have advantages like lower rates of hypoglycemia and weight gain compared to NPH.
3) Studies show that early initiation of basal insulin can help preserve beta-cell function and provide better long-term glycemic control for patients with type 2 diabetes.
Diabetes updates, DPP4 inhitors and Ramadan and DM
It is on updates on DM, OHD overview with special attention to DPP4 inhibitors and some points highlighting Ramadan and DM!
Oral surgery for diabetic patients
Diabetes mellitus is a group of metabolic diseases characterized by high blood glucose level caused by either absolute or relative deficiency of insulin. Classifications,sings and symptoms,complications,and prevalence of the disease particularly in Egypt are presented. Management of diabetic patients undergoing oral surgical procedures is discussed.
Idf course module 1 introduction to diabetes
This document provides an overview of diabetes, including defining the different types, identifying signs and symptoms, risk factors, diagnosing methods, and pathophysiology. It discusses type 1 diabetes as an autoimmune disease where the body cannot produce insulin, and type 2 diabetes where the body does not properly use or produce enough insulin. Gestational diabetes occurs during pregnancy. Diagnosis methods include fasting blood glucose, random blood glucose, oral glucose tolerance tests, and HbA1c levels. Lifestyle changes like diet and exercise can help prevent or delay type 2 diabetes.
More Related Content
What's hot
Ueda2016 symposium - pathophysiology of diabetes - abbas orabi
The document discusses pathophysiology of diabetes and treatment strategies. It summarizes that multiple defects contribute to type 2 diabetes progression, including beta-cell dysfunction from lipotoxicity, glucotoxicity, amyloid deposition, and genetics. The kidney plays an important role in glucose homeostasis by reabsorbing the majority of filtered glucose via SGLT2 transporters in the proximal tubule. In diabetes, the renal threshold for glucose is increased, allowing more glucose reabsorption and higher plasma levels. SGLT2 inhibitors lower this threshold, inducing glucosuria and reducing hyperglycemia. Clinical trials showed canagliflozin improved HbA1c and weight compared to sitagliptin when added to metformin, demonstrating its
New treatment for Diabetes Mellitus and Drugs to treat Hypoglycemia
This ppt covers recently FDA approved treatment of DM and other drugs that are in clinical pipelines or still under consideration. 2nd portion of ppt covers protocol used to treat hypoglycemia in different situations.
Ueda2016 do we know what is type 2 -assem zeyada
This document discusses type 2 diabetes, including its definition, pathogenesis, and current state of understanding. It defines type 2 diabetes as a group of metabolic disorders characterized by hyperglycemia due to defects in both insulin secretion and action. The document notes that type 2 diabetes is increasing worldwide and can now affect adolescents. It discusses the genetic and environmental factors involved in its pathogenesis, including islet cell defects and insulin resistance in tissues. While lifestyle changes and current pharmacotherapies can help manage the disease, the document concludes that the underlying mechanisms remain poorly understood and that type 2 diabetes continues to represent a major global health challenge.
Diabetes mellitus
This document discusses diabetes, including its definition, types, symptoms, management, and statistics. Some key points include:
- Diabetes is a metabolic disorder characterized by high blood glucose caused by insufficient insulin production or action.
- Over 25 million Americans have diabetes, and it is projected to affect over 333 million people worldwide by 2025, with 90% having type 2 diabetes.
- There are two main types of diabetes - type 1 is usually diagnosed in childhood and requires insulin injections, while type 2 usually occurs in adulthood and can sometimes be managed through diet and exercise.
- Symptoms vary depending on type but include increased urination, thirst, fatigue, and weight changes. Proper management is important to prevent
Dm
Diabetes mellitus is a chronic disease characterized by high blood glucose levels due to either the body not producing enough insulin or cells not responding properly to insulin. There are different types of diabetes classified by the WHO including type 1, type 2, gestational diabetes and others. The document discusses the causes, risk factors, clinical manifestations, complications and management of diabetes as well as prevention strategies and the national diabetes control program in India.
Ueda2016 workshop - hypoglycemia1 -lobna el toony
This document discusses hypoglycemia in diabetes. It defines hypoglycemia and describes its prevalence, causes, and risk factors. It notes that hypoglycemia is more common in type 1 diabetes and with intensive diabetes control. The document outlines the symptoms of mild, moderate, and severe hypoglycemia and explains how the body normally protects against low blood sugar. However, in diabetes these protective mechanisms become impaired over time, increasing the risk of severe hypoglycemia. The document discusses hypoglycemia in the context of type 1 and type 2 diabetes and provides tips for prevention and management, including recognizing risk factors, treating the underlying cause, and adjusting medications and food intake. It focuses on strategies to prevent nocturnal hypoglycemia specifically
Clinical aspects of diabetes prof alaa wafa
This document provides information on the diagnosis and management of diabetes mellitus. It begins with definitions of diabetes and descriptions of its various types. Type 1 diabetes is characterized by an autoimmune destruction of beta cells resulting in insulin deficiency, while type 2 diabetes involves insulin resistance and usually affects older individuals. Gestational diabetes occurs during pregnancy. The core defects of type 2 diabetes include insulin resistance and insulin deficiency. Lifestyle modifications and various classes of glucose-lowering medications are used to manage diabetes, with the treatment approach individualized based on each patient's case.
Kouaka diabetes ptt (2)
The document provides information about a presentation on diabetes. It will define diabetes, its causes, symptoms, and how to manage the disease. Attendees will learn to determine if they have diabetes, control blood sugar levels, and identify types 1, 2, and 3 diabetes. The presentation covers symptoms, testing blood sugar levels, diet, exercise, medications, and the importance of eating well and exercising regularly to prevent and control diabetes.
A Retrospective Study of Clinical and Biochemical Profile in Geriatric Patien...
The aim of the study was to evaluate the clinical and
biochemical characteristics of geriatric patients with type 2
diabetes mellitus (DM) attending tertiary care teaching hospital,
SVIMS, Tirupati. OBJECTIVES: To document clinical
features, biochemical parameters and anti-diabetic medications
received as per records. METHODOLOGY: This
retrospective study was performed in Department of
Endocrinology in SVIMS, Tirupati, over a period of 6 months.
Demograghic details, laboratory parameters and
pharmacotherapy details were collected in the pre-designed
annexure form. RESULTS: A total of 100 diabetic elderly
patients were included in the study. Out of which 57 were men,
43 were women. Most of them were under the age group of
60-64 years followed by other age groups. 28 patients were
having the diabetes duration of 11-15 years. Some of them were
having diabetic complications (such as diabetic retinopathy,
diabetic neuropathy, diabetic nephropathy). Among 100
patients, 32 patients were normal weight, 22 patients were
overweight, 28 patients were obese-I, 18 patients were obese-II.
About 85% of patients were having high lipid levels. Some
patients were on Oral Hypoglycemic Agents (OHAS), some
patients were using both Insulin & OHAS.CONCLUSION:
The present study comprised of 100 elderly type 2 diabetic
patients in which males were higher in number when compared
to females, most of the patients were in the age of group of
60-64 years. Hypertension was the most common co-morbidity
associated with DM followed by Coronary Artery Disease
(CAD). Diabetic neuropathy was the most prevalent
complication followed by Diabetic retinopathy and diabetic
nephropathy. In this study 46% of the patients were obese. Most
of the patients were on OHAS alone, some were on OHAS and
Insulin combination therapy while very few were on insulin
therapy alone. Dyslipidemia was present in 85% of the patients
and the most common form of dyslipidemia was low HDL and
high LD
Ueda2016 symposium - management of type 2 dm overcoming the challenges - mes...
This document provides guidance on the management of type 2 diabetes mellitus (T2DM). It discusses factors to consider when choosing oral antidiabetic drugs (OADs), including efficacy, safety, effect on weight and comorbidities. Dipeptidyl peptidase-4 (DPP-4) inhibitors like linagliptin are recommended as part of dual or triple therapy if HbA1c targets are not met with other agents. Linagliptin has advantages over other DPP-4 inhibitors in that it is primarily excreted unchanged in bile and does not require dose adjustment in patients with renal impairment. The document provides treatment algorithms for achieving glycemic control in T2DM
Diabetes mellitus part-1
This document provides information on diabetes mellitus (DM), including its classification, differences between type 1 and type 2 DM, etiology, pathophysiology, and genetics. It discusses that DM is classified based on the pathogenic process causing hyperglycemia into type 1 and type 2. Type 1 DM results from beta cell destruction leading to insulin deficiency, while type 2 DM ranges from insulin resistance with relative deficiency to a secretory defect with resistance. The document outlines the etiology and pathophysiology of both types of DM in detail. It also addresses the genetic considerations for type 1 DM.
Diabetes Mellitus
Diabetes mellitus is a metabolic disorder characterized by high blood glucose levels due to either lack of insulin production or resistance to insulin. It ranges from asymptomatic to causing severe health issues like cardiovascular disease if uncontrolled. Risk factors include genetics, obesity, physical inactivity, and diet. Prevention strategies involve education, screening high risk groups, early treatment, and ongoing management of the condition and related health factors.
THE NUTRITION THERAPY IN DIABETIC PATIENTS: A REVIEW
Diabetes Mellitus is one of the leading metabolic disorders in the world with many complications. The
management of Diabetes Mellitus can prevent many chronic diseases like stroke, myocardial infarction, diabetic
nephropathy, neuropathy and obesity. An appropriate dietary changes and lifestyle changes have proven to be
effective in the preventing and management of this disorder.Medical nutrition therapy (MNT) is an essential
component of diabetes management that comprises counseling and recommendations for dietary intake and nutrition
goals by a registered dietician (RD) or a nutrition expert to optimize metabolic control and maximize treatment
outcomes. The designing of the diet according to the nutrional needs of an individual and regular monitoring by a
dietician can provide effective results in the management. The counseling with the patient provides the detailed
information about the diet and the modifications in the diet can be made according to the age, weight, glucose level
and physical activity. The desired goal of the blood pressure, blood glucose, triglycerides can be achieved by
following the diet plan.
Type 2 Diabetes and Genes
Genes play a significant role in determining risk of developing type 2 diabetes. Having one or both parents with the condition increases risk by 15-75%, while identical twins show a 90% concordance rate. Several genes have been identified that may contribute to diabetes through effects on insulin secretion, action, fat metabolism and storage. However, environmental factors like diet and lifestyle are also important, as adoption of a Western lifestyle can increase risk even in populations that were previously low-risk. Both genes and environment interact to promote conditions like insulin resistance through their combined effects on cells and metabolism.
Management and prevention of T2DM and Hypertension
This document provides information from a presentation on preventing and managing diabetes complications. It includes:
1) Guidelines for hypertension treatment in diabetics, including a blood pressure goal of <140/90 mmHg and the recommendation that treatment includes an ACE inhibitor or ARB.
2) Evidence from the ACCORD trial showing no additional benefit of intensive blood pressure control (<120 mmHg) over standard control (<140 mmHg) for cardiovascular outcomes in diabetics. Intensive control did increase adverse events.
3) Recommendations for treating nephropathy in diabetics with an ACE inhibitor or ARB for those with modest or higher albuminuria levels.
Dm & liver
This document discusses the management of diabetes in patients with concomitant liver disease. It notes that about half of patients with cirrhosis have diabetes due to insulin resistance caused by the liver disease. Lifestyle changes and metformin are recommended initially if liver disease is mild. Insulin, sulfonylureas, meglitinides, alpha-glucosidase inhibitors, and thiazolidinediones may be used, with monitoring needed due to potential side effects or altered drug metabolism in liver disease. Insulin requirements can vary depending on the stage of liver disease.
Diabetes 1
This document provides information about diabetes mellitus. It defines diabetes as a group of metabolic diseases characterized by high blood glucose levels due to defects in insulin secretion or action. The main types of diabetes are described as type 1, type 2, and gestational diabetes. Symptoms, diagnostic criteria, risk factors, and management strategies like nutrition, exercise, medication and insulin therapy are discussed for each type. The goals of diabetes management are to control blood glucose levels through diet, exercise, oral hypoglycemic drugs, and insulin in order to prevent long-term health complications.
Cme ppt final with images
The document discusses caring for people with diabetes by providing an overview of the disease. It covers understanding diabetes, types of diabetes, common symptoms, diagnosing diabetes through blood glucose testing, dangers of high blood glucose levels over time including damage to blood vessels and nerves, goals of treatment, the four pillars of diabetes management including diet, exercise, self-monitoring of blood glucose, and pharmacological treatment including oral medications and insulin therapy. It also addresses potential complications such as hypoglycemia and how to treat low blood sugar.
Role of early basal insulin initiation of t2 dm
1) The document discusses guidelines for initiating basal insulin therapy in patients with type 2 diabetes, including benefits such as lowering HbA1c and reducing cardiovascular risk.
2) It compares different basal insulin options like glargine, detemir, and NPH insulin, finding that the long-acting analogs glargine and detemir have advantages like lower rates of hypoglycemia and weight gain compared to NPH.
3) Studies show that early initiation of basal insulin can help preserve beta-cell function and provide better long-term glycemic control for patients with type 2 diabetes.
Diabetes updates, DPP4 inhitors and Ramadan and DM
It is on updates on DM, OHD overview with special attention to DPP4 inhibitors and some points highlighting Ramadan and DM!
What's hot (20)
Ueda2016 symposium - pathophysiology of diabetes - abbas orabi
Ueda2016 symposium - pathophysiology of diabetes - abbas orabi
New treatment for Diabetes Mellitus and Drugs to treat Hypoglycemia
New treatment for Diabetes Mellitus and Drugs to treat Hypoglycemia
A Retrospective Study of Clinical and Biochemical Profile in Geriatric Patien...
A Retrospective Study of Clinical and Biochemical Profile in Geriatric Patien...
Ueda2016 symposium - management of type 2 dm overcoming the challenges - mes...
Ueda2016 symposium - management of type 2 dm overcoming the challenges - mes...
THE NUTRITION THERAPY IN DIABETIC PATIENTS: A REVIEW
THE NUTRITION THERAPY IN DIABETIC PATIENTS: A REVIEW
Management and prevention of T2DM and Hypertension
Management and prevention of T2DM and Hypertension
Diabetes updates, DPP4 inhitors and Ramadan and DM
Diabetes updates, DPP4 inhitors and Ramadan and DM
Similar to Diabetes 2
Oral surgery for diabetic patients
Diabetes mellitus is a group of metabolic diseases characterized by high blood glucose level caused by either absolute or relative deficiency of insulin. Classifications,sings and symptoms,complications,and prevalence of the disease particularly in Egypt are presented. Management of diabetic patients undergoing oral surgical procedures is discussed.
Idf course module 1 introduction to diabetes
This document provides an overview of diabetes, including defining the different types, identifying signs and symptoms, risk factors, diagnosing methods, and pathophysiology. It discusses type 1 diabetes as an autoimmune disease where the body cannot produce insulin, and type 2 diabetes where the body does not properly use or produce enough insulin. Gestational diabetes occurs during pregnancy. Diagnosis methods include fasting blood glucose, random blood glucose, oral glucose tolerance tests, and HbA1c levels. Lifestyle changes like diet and exercise can help prevent or delay type 2 diabetes.
Diabetes and new anti diabetic drugs
This document discusses diabetes and new antidiabetic drugs. It notes that diabetes cases are rising significantly worldwide and that diabetes increases the risk of serious health complications. It describes the different types of diabetes and their presentations. It recommends screening guidelines for prediabetes and notes the importance of lifestyle changes to prevent progression to diabetes. It discusses treatment targets and factors like hypoglycemia. It also provides an overview of various drug classes used to treat diabetes, including their mechanisms and effects.
2010 exenatide and weight loss
This document reviews the effects of exenatide, a glucagon-like peptide-1 receptor agonist, on weight loss. It summarizes findings from clinical trials that reported consistent weight loss associated with exenatide treatment compared to placebo. Exenatide is thought to cause weight loss by decreasing energy intake through effects on satiety and by possibly increasing energy expenditure, though evidence for each mechanism is inconsistent. Further research is needed to better understand the mechanisms through which exenatide induces weight loss.
diabetes.pdf
Diabetes is a chronic health condition that affects how the body converts food into energy. There are two main types of diabetes: type 1 and type 2. In type 1 diabetes, the body doesn't produce enough insulin, a hormone that regulates blood sugar levels. In type 2 diabetes, the body becomes resistant to insulin or doesn't produce enough insulin.
High blood sugar levels associated with diabetes can cause a range of health problems, including nerve damage, kidney disease, and heart disease. Managing diabetes involves monitoring blood sugar levels, taking medications, and making lifestyle changes such as eating a healthy diet and exercising regularly.
If you have diabetes, it's important to work closely with your healthcare provider to develop a treatment plan that meets your individual needs. This may include regular blood sugar testing, taking medications as prescribed, and making lifestyle changes to help manage your condition.
Newer Anti-Hyperglycemic agents in type 2 Diabetes Mellitus e Expanding the h...
Diabetes mellitus is a common, chronic and progressive disease resulting in micro and macrovascular complications. Many classes of drugs are available for treatment but still the search for newer anti-hyperglycemic agents continues to combat significant adverse effect profile, loss of efficacy, progressive nature of disease and improve patient compliance. New emerging therapies in pipeline include drugs targeting various pathophysiologic mechanisms like incretin based therapies, sodium glucose co-transporter inhibitors, glucokinase inhibitors, 11b hydroxy steroid dehydrogenase inhibitors, drugs modulating fatty acid metabolism, selective PPARg receptor modulators and anti inflammatory agents.
Modern therapy in diabetics with cad scintic day
This document provides information on modern therapy for diabetics with coronary artery disease. It discusses the following key points in 3 sentences:
Diabetes is a global epidemic that is increasing worldwide. Cardiovascular disease is the leading cause of death for diabetics, as they face comparable heart attack risks to those with a previous heart attack. The document reviews guidelines for glycemic, blood pressure, and lipid control to reduce cardiovascular risks and discusses various drug therapy options for treating diabetes in patients with cardiovascular disease.
Diabetes
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
FORA_Patient_Brochure
This document discusses diabetes and measurements of glucose levels and glycemic control. It covers:
- Blood and plasma glucose levels are tightly controlled in healthy individuals but can change with stress or disease like diabetes. Modern devices can measure blood or plasma glucose levels.
- The two main types of diabetes are type 1 (lack of insulin production) and type 2 (insulin resistance and relative insulin deficiency). Both can lead to hyperglycemia if not properly treated.
- Uncontrolled hyperglycemia can cause serious complications affecting eyes, kidneys, nerves, heart and other organs. But with modern treatment and monitoring, many patients can live normal lives.
Management Of Diabetes
This document summarizes the management and treatment of diabetes. It discusses:
1) The classification of type 1 and type 2 diabetes, their typical presentations, and diagnostic criteria.
2) Guidelines for initial treatment including lifestyle changes and metformin for type 2 diabetes. Adding sulfonylureas or insulin if glycemic goals are not met.
3) Treatment of type 1 diabetes focuses on intensive insulin therapy to control blood glucose and reduce complications.
4) Screening and treatment of complications like nephropathy, retinopathy, and neuropathy are also covered.
Diabetes mellitus: The Pandemic of 21st Century!
Diabetes mellitus is a major global metabolic disorder of 21 st century. This is due to its broad spectrum of associated complications with risks, like cardiac and renal disorders. The rapid growth of diabetes is becoming a major burden upon healthcare facilities in all affected countries. Due to lack of definitive preventative measures of diabetes, we must be aware of this pandemic and follow a disciplined lifestyle to limit it. In this communication, recent advances in diabetes management and current preventative measures have been concluded.
1. Insuline and Anti diabetics
This document outlines a lecture on diabetes and antidiabetic drugs. It discusses the synthesis, mechanism of action, and role of insulin. It also covers the diagnosis and symptoms of insulin-related disorders, classification of antidiabetic drugs and their mechanisms of action, pharmacotherapeutics of diabetic disorders, and types and management of diabetes mellitus. The document is compiled by Prof. Anwar Baig of Anjuman I Islam's Kalsekar Technical Campus School of Pharmacy.
A Review on Diabetes Mellitus Type II
This document summarizes a review article on type 2 diabetes mellitus. It discusses the pathophysiology, epidemiology, screening, diagnosis, and management of type 2 diabetes. Some key points include:
- Type 2 diabetes is characterized by insulin resistance and impaired insulin secretion, accounting for 90% of diabetes cases worldwide.
- Rates of type 2 diabetes have increased dramatically in recent decades due to obesity and decreased exercise.
- Screening for type 2 diabetes involves measuring fasting plasma glucose levels, and an oral glucose tolerance test may also be used for diagnosis.
- Management of type 2 diabetes focuses on lifestyle changes as well as medications to lower blood sugar and prevent complications.
International Journal of Pharmaceutical Science Invention (IJPSI)
International Journal of Pharmaceutical Science Invention (IJPSI) is an international journal intended for professionals and researchers in all fields of Pahrmaceutical Science. IJPSI publishes research articles and reviews within the whole field Pharmacy and Pharmaceutical Science, new teaching methods, assessment, validation and the impact of new technologies and it will continue to provide information on the latest trends and developments in this ever-expanding subject. The publications of papers are selected through double peer reviewed to ensure originality, relevance, and readability. The articles published in our journal can be accessed online.
Diabetes case-study
The document provides an overview of diabetes mellitus, including the different types (Type 1, Type 2, gestational), signs and symptoms, causes, and statistical data on prevalence worldwide and in the Philippines. It then discusses a case study of a 71-year old Filipino man diagnosed with diabetes. It outlines his medical history, including a family history of diabetes, and analyzes factors affecting his nutrition and eating patterns such as his beliefs about food, personal preferences for oily and sweet foods, sedentary lifestyle, and lack of religious dietary restrictions.
Diabetes mellitus (dm) And DKA
This document provides information about diabetes mellitus (DM) and diabetic ketoacidosis (DKA). It discusses the main types of DM including type 1, type 2, and gestational diabetes. Type 1 results from pancreatic failure to produce insulin, type 2 from insulin resistance, and gestational occurs in pregnant women. Worldwide, 382 million people have DM. Management focuses on diet, exercise, medication and monitoring to control blood sugar levels. Insulin is used to treat type 1 and sometimes type 2 DM, while other classes of oral medications are also used to treat type 2.
Diabetes mellitus (dm) and DKA
This document provides information about diabetes mellitus (DM) and diabetic ketoacidosis (DKA). It discusses the main types of DM including type 1, type 2, and gestational diabetes. Type 1 results from pancreatic failure to produce insulin, while type 2 begins with insulin resistance and can later include insulin deficiency. Gestational diabetes occurs in pregnant women without prior history. The document also covers epidemiology, pathophysiology, diagnosis, management, treatment options including insulin, oral medications, diet/exercise, and complications of uncontrolled diabetes.
Final balatbat ppt
This document discusses factors affecting compliance of type 2 diabetic employees in an occupational setting. It provides background on the increasing prevalence of diabetes globally and in the Philippines. Maintaining compliance with treatment regimens is important for diabetic employees' health and job performance, but can be challenging. The study aims to identify factors like psychological, social, healthcare, and disease/treatment aspects that influence medication compliance among diabetic manufacturing company employees in the Philippines. It will focus on employees taking oral medications for at least three years.
What are the Current or Changing Standards of Care for Diabetic Clients?
What are the Current or Changing Standards of Care for Diabetic Clients?Virginia Rural Health Association
The updated standards of care for diabetic patients. Topcs include a discussion of diagnostic testing, insulin and oral therapies as well as life style strategies.DM PPT.pptx
This document provides an overview of diabetes mellitus (DM), including its causes, symptoms, types, complications, management, and prevention. DM is characterized by high blood glucose levels due to defects in insulin production or action. It can cause damage to various organs and is associated with cardiovascular and other diseases. There are three main types of DM: type 1, type 2, and gestational diabetes. Lifestyle changes including diet and exercise are the primary treatment approach. If blood glucose levels remain high, oral medications and/or insulin may be needed to manage the condition. Early detection and treatment can help prevent or delay diabetes and its complications.
Similar to Diabetes 2 (20)
Newer Anti-Hyperglycemic agents in type 2 Diabetes Mellitus e Expanding the h...
Newer Anti-Hyperglycemic agents in type 2 Diabetes Mellitus e Expanding the h...
International Journal of Pharmaceutical Science Invention (IJPSI)
International Journal of Pharmaceutical Science Invention (IJPSI)
What are the Current or Changing Standards of Care for Diabetic Clients?
What are the Current or Changing Standards of Care for Diabetic Clients?
Recently uploaded
Osteoporosis - Definition , Evaluation and Management .pdf
Osteoporosis is an increasing cause of morbidity among the elderly.
In this document , a brief outline of osteoporosis is given , including the risk factors of osteoporosis fractures , the indications for testing bone mineral density and the management of osteoporosis
Part II - Body Grief: Losing parts of ourselves and our identity before, duri...
Learn about body grief and ways to cope with it. We will also explore methods to heal from this challenging experience.
Histololgy of Female Reproductive System.pptx
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
Efficacy of Avartana Sneha in Ayurveda
Avartana Sneha is a unique method of Preparation of Sneha Kalpana in Ayurveda, mainly it is indicated for the Vataja rogas.
Top Effective Soaps for Fungal Skin Infections in India
Swisschem Dermacare has mentioned the List of The Best Antifungal Soap In India 2022. All of these soaps are trusted by various Dermatology Experts.
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptx
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptxHolistified Wellness
We’re talking about Vedic Meditation, a form of meditation that has been around for at least 5,000 years. Back then, the people who lived in the Indus Valley, now known as India and Pakistan, practised meditation as a fundamental part of daily life. This knowledge that has given us yoga and Ayurveda, was known as Veda, hence the name Vedic. And though there are some written records, the practice has been passed down verbally from generation to generation.Does Over-Masturbation Contribute to Chronic Prostatitis.pptx
In some case, your chronic prostatitis may be related to over-masturbation. Generally, natural medicine Diuretic and Anti-inflammatory Pill can help mee get a cure.
Hemodialysis: Chapter 4, Dialysate Circuit - Dr.Gawad
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Integrating Ayurveda into Parkinson’s Management: A Holistic Approach
Explore the benefits of combining Ayurveda with conventional Parkinson's treatments. Learn how a holistic approach can manage symptoms, enhance well-being, and balance body energies. Discover the steps to safely integrate Ayurvedic practices into your Parkinson’s care plan, including expert guidance on diet, herbal remedies, and lifestyle modifications.
Role of Mukta Pishti in the Management of Hyperthyroidism
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
Journal Article Review on Rasamanikya
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
REGULATION FOR COMBINATION PRODUCTS AND MEDICAL DEVICES.pptx
It includes regulation of combination products and medical devices. FDA and industry liaisons.
Recently uploaded (20)
Muscles of Mastication by Dr. Rabia Inam Gandapore.pptx
Muscles of Mastication by Dr. Rabia Inam Gandapore.pptx
Tests for analysis of different pharmaceutical.pptx
Tests for analysis of different pharmaceutical.pptx
Osteoporosis - Definition , Evaluation and Management .pdf
Osteoporosis - Definition , Evaluation and Management .pdf
Part II - Body Grief: Losing parts of ourselves and our identity before, duri...
Part II - Body Grief: Losing parts of ourselves and our identity before, duri...
Top Effective Soaps for Fungal Skin Infections in India
Top Effective Soaps for Fungal Skin Infections in India
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptx
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptx
Does Over-Masturbation Contribute to Chronic Prostatitis.pptx
Does Over-Masturbation Contribute to Chronic Prostatitis.pptx
Hemodialysis: Chapter 4, Dialysate Circuit - Dr.Gawad
Hemodialysis: Chapter 4, Dialysate Circuit - Dr.Gawad
Integrating Ayurveda into Parkinson’s Management: A Holistic Approach
Integrating Ayurveda into Parkinson’s Management: A Holistic Approach
Role of Mukta Pishti in the Management of Hyperthyroidism
Role of Mukta Pishti in the Management of Hyperthyroidism
REGULATION FOR COMBINATION PRODUCTS AND MEDICAL DEVICES.pptx
REGULATION FOR COMBINATION PRODUCTS AND MEDICAL DEVICES.pptx
Diabetes 2
- 1. Atreyi Banerjee Pipeline products in Phase III
- 7. Five major drugs under phase III clinical trial for Type-2 diabetes
- 15. X X The average duration of study is 2 years and 6 months as calculated from www.clinicaltrials.gov Disease Progression Duration of trials Survival (X) X X X Censored
- 18. Overall categorization of diabetes treatments
- 19. The key market players at present are Hoffmann-La Roche, Novo Nordisk, Merck & Co., Novartis Ag, Sanofi-aventis, Eli Lilly & Company and GlaxoSmithKline reinstated by the figure above. Competitive dynamics of the leading players in the global diabetes market, 2005
- 20. Global* market share of leading insulins (%), 1999-2003 , The leading giant still is the US with more than 50% market share while the Pacific region is still growing owing to the large population of Diabetic patients in Japan and South Asia.