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DELAYED
FRACTURE
HEALING
By :
Nabilla Huda binti Mustapa
COHORT 1A
SLOW
UNION
DELAYED
UNION
NON-
UNION
SLOW UNION
– Fractures takes longer than usual to unite, but
passes through the normal clinical and radiological
stages of healing without any departure from
normal
– Mx : Reassurance of the patient
DELAYED
UNION
DEFINITION  Healing has not advanced at the
average rate for the location and type of
fracture for three months.
• Biological process of repair is continuous.
–As compared to slow union, radiographs
may show abnormal bone changes.
–There is, however, no sclerosis of the bone
ends.
CAUSES
• Inadequate blood flow
• Severe tissue damage
• Periosteal stripping
Management
– The problem is to differentiate between delayed
union which is going to proceed with proper
encouragement to union, and delayed union
which is going to go on to non-union
– Disadvantage of delaying intervention :
irreversible stiffness in joints which are
immobilised with the fracture
Treatment
• CONSERVATIVE
 Encourage muscular exercise and weight
bearing by case or brace
• OPERATIVE
Internal fixation or Bone graft
NON UNION
DEFINITION  A minimum of nine months has past
since the injury and the fracture shows no clinical
and radiological progressive signs of healing
continuously.
• Complete suspension of biological process of
repair.
– Radiological changes which indicate that this situation
will be permanent.
– i.e. the fracture will never unite unless there is some
fundamental alteration in the line of treatment.
Types of non-union
(muller and weber)
a. Hypervascular b. Avascular
• # ends are viable and capable of
biological reaction
• Rigid internal fixation is enough
• # ends are inert and incapable of
biological reaction.
• Rigid internal fixation with bone
grafting is required
1. Elephant foot non union 1. Torsion wedge non union
• It is seen in segmental #
2. Horse hoof non union 2. Comminuted non union
• It is seen in comminuted #
3. Oligotrophic non union 3. Defect non union
• Seen in open fractures.
4. Atrophic non union
• The ends are tapered thin and sclerotic
with excessive scar tissue in between
Septic
Non-union
with
underlying
osteomyelitis
Aseptic
Hypertrophic Non-union
(Pseudarthrosis)
Excessive callus formations
around the fracture gap →
d/t insufficient stability of
the internal fixator
‘Elephant Foot’
Bone ends appear sclerotic
and are flared out 
diameter of the bone
fragments at the level of the
fracture is increased
Fracture line is clearly visible,
Gap being filled with cartilage and
fibrous tissue cells
Good blood supply
(eventhough increase in
bone density)
Atrophic Non-union
No callus formations
 d/t impaired
healing process
No evidence of cellular activity
at the level of the fracture
Bone ends are narrow,
rounded and osteoporotic
Frequently Avascular
Types of Non-union
“Elephant foot” appearance
CAUSES OF NON-UNION
Injury
Distraction
at fracture
site
Soft tissue
loss
Bone loss
Soft tissue
interposition
Bone
Poor blood
supply
Hematoma
Infection
Pathological
lesion
Surgeon
Poor
splintage
Poor
fixation
Impatience
Patient
Age
Poor
medical
condition
Smoking
and
Alcohol
Drugs
NSAIDs
Fluoro-
quinolone
MANAGEMENT
1. Open reduction and bone grafting
2. Electrical stimulation
3. Rigid internal fixation by DCP/interlocking nail Âą
Bone grafting.
4. Ilizarov’s technique
Difference between
non-union and delayed union
NON UNION DELAYED UNION
• No bony tenderness
• No bony crepitus
• Frank painless abnormal
mobility at fracture site.
Clinical
Features
• Bony tenderness present
• No bony crepitus
• A little (painful) or no abnormal
mobility at fracture site
Visible # line without bridging
callus.
The fragments are rounded
smooth and sclerotic.
 The medullary canal may be
obliterated.
X-Ray Visible # line with inadequate callus
bridging the fracture site.
It is absolute indication for surgery
(no role of conservative treatment).
Treatment Conservative – prolonged
immobilization for longer period
(sometimes it may need surgical
intervention)
THANK YOU

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Delayed fracture healing

  • 4. – Fractures takes longer than usual to unite, but passes through the normal clinical and radiological stages of healing without any departure from normal – Mx : Reassurance of the patient
  • 6. DEFINITION  Healing has not advanced at the average rate for the location and type of fracture for three months. • Biological process of repair is continuous. –As compared to slow union, radiographs may show abnormal bone changes. –There is, however, no sclerosis of the bone ends.
  • 7. CAUSES • Inadequate blood flow • Severe tissue damage • Periosteal stripping
  • 8. Management – The problem is to differentiate between delayed union which is going to proceed with proper encouragement to union, and delayed union which is going to go on to non-union – Disadvantage of delaying intervention : irreversible stiffness in joints which are immobilised with the fracture
  • 9. Treatment • CONSERVATIVE  Encourage muscular exercise and weight bearing by case or brace • OPERATIVE Internal fixation or Bone graft
  • 11. DEFINITION  A minimum of nine months has past since the injury and the fracture shows no clinical and radiological progressive signs of healing continuously. • Complete suspension of biological process of repair. – Radiological changes which indicate that this situation will be permanent. – i.e. the fracture will never unite unless there is some fundamental alteration in the line of treatment.
  • 12. Types of non-union (muller and weber) a. Hypervascular b. Avascular • # ends are viable and capable of biological reaction • Rigid internal fixation is enough • # ends are inert and incapable of biological reaction. • Rigid internal fixation with bone grafting is required 1. Elephant foot non union 1. Torsion wedge non union • It is seen in segmental # 2. Horse hoof non union 2. Comminuted non union • It is seen in comminuted # 3. Oligotrophic non union 3. Defect non union • Seen in open fractures. 4. Atrophic non union • The ends are tapered thin and sclerotic with excessive scar tissue in between
  • 13. Septic Non-union with underlying osteomyelitis Aseptic Hypertrophic Non-union (Pseudarthrosis) Excessive callus formations around the fracture gap → d/t insufficient stability of the internal fixator ‘Elephant Foot’ Bone ends appear sclerotic and are flared out  diameter of the bone fragments at the level of the fracture is increased Fracture line is clearly visible, Gap being filled with cartilage and fibrous tissue cells Good blood supply (eventhough increase in bone density) Atrophic Non-union No callus formations  d/t impaired healing process No evidence of cellular activity at the level of the fracture Bone ends are narrow, rounded and osteoporotic Frequently Avascular Types of Non-union
  • 15. CAUSES OF NON-UNION Injury Distraction at fracture site Soft tissue loss Bone loss Soft tissue interposition Bone Poor blood supply Hematoma Infection Pathological lesion Surgeon Poor splintage Poor fixation Impatience Patient Age Poor medical condition Smoking and Alcohol Drugs NSAIDs Fluoro- quinolone
  • 16. MANAGEMENT 1. Open reduction and bone grafting 2. Electrical stimulation 3. Rigid internal fixation by DCP/interlocking nail Âą Bone grafting. 4. Ilizarov’s technique
  • 17. Difference between non-union and delayed union NON UNION DELAYED UNION • No bony tenderness • No bony crepitus • Frank painless abnormal mobility at fracture site. Clinical Features • Bony tenderness present • No bony crepitus • A little (painful) or no abnormal mobility at fracture site Visible # line without bridging callus. The fragments are rounded smooth and sclerotic.  The medullary canal may be obliterated. X-Ray Visible # line with inadequate callus bridging the fracture site. It is absolute indication for surgery (no role of conservative treatment). Treatment Conservative – prolonged immobilization for longer period (sometimes it may need surgical intervention)