The presentation we gave at two workshops on Open Access policies organised by EU-funded project PASTEUR4OA on 9 & 10 February 2016 in Brussels. Basically, nothing really new, but this is probably the shortest presentation we have made to present the European Commission mandate for open access in Horizon 2020.
A research-friendly copyright environment in the digital age: a European pers...Jean-François Dechamp
A 30-minute presentation that builds the case for a copyright exception for scientific research in the European legislation, in order to allow data analytics (Text and Data Mining / TDM)
The presentation we gave at two workshops on Open Access policies organised by EU-funded project PASTEUR4OA on 9 & 10 February 2016 in Brussels. Basically, nothing really new, but this is probably the shortest presentation we have made to present the European Commission mandate for open access in Horizon 2020.
A research-friendly copyright environment in the digital age: a European pers...Jean-François Dechamp
A 30-minute presentation that builds the case for a copyright exception for scientific research in the European legislation, in order to allow data analytics (Text and Data Mining / TDM)
OpenAIRE webinar on Open Access in H2020 (OAW2016)OpenAIRE
OpenAIRE Webinar for project coordinators and researchers on Open Access to publications in H2020 - By Eloy Rodrigues and Pedro Principe (University of Minho, OpenAIRE Helpdesk & Training managers). Open Access Week 2016 initiatives.
The FP7 Post-Grant Open Access Pilot: An All-Encompassing Gold Open Access Fu...OpenAIRE
A year into the EC FP7 Post-Grant Open Access Pilot, this presentation delivered at the LIBER Annual Conference 2016 in Helsinki shows the current progress of this funding initiative. This Gold OA Pilot has currently two funding worklines, a main one for APC/BPC payments for post-grant manuscripts arising from finished FP7 projects and an alternative funding mechanism for supporting APC-free OA journals and platforms. Detailed figures are provided for the APC payments made so far, together with a number of findings the initiative has already come upon.
Evolving Strategies for Open Access Implementation: Some Findings from the Op...OpenAIRE
A year an a half into its implementation, the EC post-grant funding initiative for FP7 projects run under the OpenAIRE2020 project is already producing some findings, both in the area of APC-based Gold Open Access and in providing support to APC-free Open Access journals and platforms. While exploring the rather fragmented Open Access landscape across Europe, this presentation will look into the evolution of the multiple parallel strategies for Open Access implementation under the light of the work carried out within this post-grant funding initiative. It's argued that a widespread progress will require support for the different co-existing strategies.
This presentation was delivered at the PUBMET2016 conference in Zadar, Croatia, http://pubmet.unizd.hr/
Vortrag im Rahmen der EERA-Session: Open Science and Educational Research? Inclusion and Exclusion at the European Open Science Cloud; am 5. September 2018 in Bolzano (Italien).
European Commission
DG Research and Innovation
RTD.A2. Open Data Policy and Science Cloud
Katarzyna Szkuta
Marina Angelaki - PASTEUR4OA: Supporting Open Access PoliciesOpenAIRE
Presentation given as part of OpenAIRE Webinar "Policies for Open Science: webinar for research managers and policy makers", Open Access Week 2016 (27.10.2016)
Infrastructure for the Data Revolution: How OpenAIRE supports the EC’s Open ...OpenAIRE
OpenAIRE2020 is an Open Access (OA) infrastructure for research which supports open scholarly communication and access to the research output of European funded projects. With over five years experience of supporting the European Commission’s OA policies, OpenAIRE now has a key role in supporting the EC’s Horizon 2020 Open Data Pilot. OpenAIRE’s community network works to gather research outputs, highlight the OA mandate, and advance open access initiatives at national levels. It has National Open Access Desks in over 30 countries, and operates a European Helpdesk system for all matters concerning open access, copyright and repository interoperability. At the same time, OpenAIRE harvests metadata information from a network of Open Access repositories, data repositories, aggregators and OA journals. It then enriches this metadata by linking people, publications, datasets, projects and funding streams. This interlinked information – which currently encompasses more than 13 million publications and 12 thousand datasets from more than 6 thousand data sources – helps optimise the research process, increasing research visibility, facilitating data sharing and reuse and enabling the monitoring of research impact. This presentation will outline how an infrastructure like OpenAIRE can help turn OA policy into successful implementation.
Peer Review on the Move from Closed to OpenOpenAIRE
Presented to the 20th International Conference on Electronic Publishing (ELPUB2016), Goettingen, Germany, 8th June 2016 by Tony Ross-Hellauer
Abstract: Openness in peer review is no longer a terra incognita. However, there remains a need for further experimentation and careful evaluation of its advantages and disadvantages in practice. OpenAIRE, the European digital infrastructure for Open Scholarship, offers a unique environment for such experiments. This paper describes the design and early results of three such experiments developed in close collaboration with selected publishing and repository communities.
OA Conference Proceedings: http://ebooks.iospress.nl/publication/42901
Open Research Data: Present and planned EC Policy, Jean-Claude Burgelman impl...Platforma Otwartej Nauki
“Open Research Data: Implications for Science and Society”, Warsaw, Poland, May 28–29, 2015. The conference was organized by the Open Science Platform — an initiative of the Interdisciplinary Centre for Mathematical and Computational Modelling at the University of Warsaw. pon.edu.pl @OpenSciPlatform #ORD2015
The section provides an overview of the open science requirements and how to comply with them stipulated by selected funders and organizations: H2020 & ERC, FWO and Belspo by Emilie Hermans
The European Commission's proposal for embedding open science in horizon europe. Particular emphasis on open access and research data management aspects. Also presenting the new publishing platform of the Commission, Open Research Europe
OpenAIRE-COAR conference 2014: Open Access in H2020, by Anni Hellman - Europe...OpenAIRE
Presentation at the OpenAIRE-COAR Conference: "Open Access Movement to Reality: Putting the Pieces Together", Athens - May 21-22, 2014.
Open Access in H2020, by Anni Hellman - European Commission.
OpenAIRE webinar on Open Access in H2020 (OAW2016)OpenAIRE
OpenAIRE Webinar for project coordinators and researchers on Open Access to publications in H2020 - By Eloy Rodrigues and Pedro Principe (University of Minho, OpenAIRE Helpdesk & Training managers). Open Access Week 2016 initiatives.
The FP7 Post-Grant Open Access Pilot: An All-Encompassing Gold Open Access Fu...OpenAIRE
A year into the EC FP7 Post-Grant Open Access Pilot, this presentation delivered at the LIBER Annual Conference 2016 in Helsinki shows the current progress of this funding initiative. This Gold OA Pilot has currently two funding worklines, a main one for APC/BPC payments for post-grant manuscripts arising from finished FP7 projects and an alternative funding mechanism for supporting APC-free OA journals and platforms. Detailed figures are provided for the APC payments made so far, together with a number of findings the initiative has already come upon.
Evolving Strategies for Open Access Implementation: Some Findings from the Op...OpenAIRE
A year an a half into its implementation, the EC post-grant funding initiative for FP7 projects run under the OpenAIRE2020 project is already producing some findings, both in the area of APC-based Gold Open Access and in providing support to APC-free Open Access journals and platforms. While exploring the rather fragmented Open Access landscape across Europe, this presentation will look into the evolution of the multiple parallel strategies for Open Access implementation under the light of the work carried out within this post-grant funding initiative. It's argued that a widespread progress will require support for the different co-existing strategies.
This presentation was delivered at the PUBMET2016 conference in Zadar, Croatia, http://pubmet.unizd.hr/
Vortrag im Rahmen der EERA-Session: Open Science and Educational Research? Inclusion and Exclusion at the European Open Science Cloud; am 5. September 2018 in Bolzano (Italien).
European Commission
DG Research and Innovation
RTD.A2. Open Data Policy and Science Cloud
Katarzyna Szkuta
Marina Angelaki - PASTEUR4OA: Supporting Open Access PoliciesOpenAIRE
Presentation given as part of OpenAIRE Webinar "Policies for Open Science: webinar for research managers and policy makers", Open Access Week 2016 (27.10.2016)
Infrastructure for the Data Revolution: How OpenAIRE supports the EC’s Open ...OpenAIRE
OpenAIRE2020 is an Open Access (OA) infrastructure for research which supports open scholarly communication and access to the research output of European funded projects. With over five years experience of supporting the European Commission’s OA policies, OpenAIRE now has a key role in supporting the EC’s Horizon 2020 Open Data Pilot. OpenAIRE’s community network works to gather research outputs, highlight the OA mandate, and advance open access initiatives at national levels. It has National Open Access Desks in over 30 countries, and operates a European Helpdesk system for all matters concerning open access, copyright and repository interoperability. At the same time, OpenAIRE harvests metadata information from a network of Open Access repositories, data repositories, aggregators and OA journals. It then enriches this metadata by linking people, publications, datasets, projects and funding streams. This interlinked information – which currently encompasses more than 13 million publications and 12 thousand datasets from more than 6 thousand data sources – helps optimise the research process, increasing research visibility, facilitating data sharing and reuse and enabling the monitoring of research impact. This presentation will outline how an infrastructure like OpenAIRE can help turn OA policy into successful implementation.
Peer Review on the Move from Closed to OpenOpenAIRE
Presented to the 20th International Conference on Electronic Publishing (ELPUB2016), Goettingen, Germany, 8th June 2016 by Tony Ross-Hellauer
Abstract: Openness in peer review is no longer a terra incognita. However, there remains a need for further experimentation and careful evaluation of its advantages and disadvantages in practice. OpenAIRE, the European digital infrastructure for Open Scholarship, offers a unique environment for such experiments. This paper describes the design and early results of three such experiments developed in close collaboration with selected publishing and repository communities.
OA Conference Proceedings: http://ebooks.iospress.nl/publication/42901
Open Research Data: Present and planned EC Policy, Jean-Claude Burgelman impl...Platforma Otwartej Nauki
“Open Research Data: Implications for Science and Society”, Warsaw, Poland, May 28–29, 2015. The conference was organized by the Open Science Platform — an initiative of the Interdisciplinary Centre for Mathematical and Computational Modelling at the University of Warsaw. pon.edu.pl @OpenSciPlatform #ORD2015
The section provides an overview of the open science requirements and how to comply with them stipulated by selected funders and organizations: H2020 & ERC, FWO and Belspo by Emilie Hermans
The European Commission's proposal for embedding open science in horizon europe. Particular emphasis on open access and research data management aspects. Also presenting the new publishing platform of the Commission, Open Research Europe
OpenAIRE-COAR conference 2014: Open Access in H2020, by Anni Hellman - Europe...OpenAIRE
Presentation at the OpenAIRE-COAR Conference: "Open Access Movement to Reality: Putting the Pieces Together", Athens - May 21-22, 2014.
Open Access in H2020, by Anni Hellman - European Commission.
“Open Research Data: Implications for Science and Society”, Warsaw, Poland, May 28–29, 2015, conference organized by the Open Science Platform — an initiative of the Interdisciplinary Centre for Mathematical and Computational Modelling at the University of Warsaw. pon.edu.pl @OpenSciPlatform #ORD2015
A presentation given on the Horizon 2020 open data pilot as part of a series of OpenAIRE webinars for Open Access week 2014 - http://www.fosteropenscience.eu/event/openaire-webinars-during-oa-week-2014
The Horizon 2020 Open Data Pilot - OpenAIRE webinar (Oct. 21 2014) by Sarah J...OpenAIRE
Sarah Jones (HATII, Digital Curation Center) will provide more information on the Open Research Data Pilot in H2020: who should participate and how to comply (in collaboration with FOSTER)
Date: Tuesday, October 21 2014
Presentation of open science requirements in Horizon Europe for the Research and Innovation Foundation in Cyprus. Analyzes requirements of model grant agreement (publications, research data, additional open science practices, open science and evaluation process, open research europe.
The present report is the analysis of the answers to the questionnaire that the European Commission prepared on open access and preservation policies in Europe, with a view to taking stock in 2011 of the status of implementation of the 2007 Council conclusions on scientific information in the digital age.
A workshop held in Brussels in November 2010 gathered around 20 invited national experts from EU Member States, with the aims of getting an understanding of Member States’ implementation of the 2007 Council Conclusions on scientific information in the digital age. This report documents the proceedings, sets them in the context of developments so far on open access and preservation at an international level and makes a set of recommendations for future EC action.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed.
In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine.
Bio
Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
1. Open Access et gestion des données :
quel agenda pour la recherche
scientifique européenne ?
(Slides follow in EN)
Jean-François Dechamp
Commission européenne, Direction-Générale Recherche et Innovation
jean-francois.dechamp@ec.europa.eu
2. The European Commission is a...
● Policy maker
– It propose EU legislation & it legislates
with other EU institutions
– It invites Member States to act
● Funding agency
– It sets its own access and
dissemination rules for EC-funded
research
● Capacity builder
– It funds project that support EC/EU
policy
3. A new European Commission (2014-19)
Andrus Ansip, Vice-President, Digital Single Market
Günther Oettinger, Carlos Moedas,
Commissioner for Digital Commissioner for Research,
Economy and Society Science and Innovation
4. Commissioner's view
"Open Science, of which Open Access is an
important part, will be vital to ensuring
European progress and prosperity in the
future"
(Speech at NETHER, January 26, 2015)
5. What do we understand by OA?
● OA = online access at no charge to the user
– To peer-reviewed scientific publications
– To research data
● Two main OA publishing business models
– Self-archiving: 'traditional' publication plus deposit of
manuscripts in a repository ('Green OA')
Both versions contain the same peer-reviewed content, but may be
differently formatted
– OA publishing: immediate OA provided by publisher ('Gold OA')
Usually (not always) 'Author-pay' model (APC)
Some journals offer both subscriptions and open access publishing to
selected on-line articles (hybrid journals)
6. What OA is not
● Not an obligation to publish
● Not at odds with patenting (see graph)
● OA publications go the same peer review process
8. The Commission objective
● Optimise the impact of publicly-funded scientific
research
– At European level (FP7 & Horizon 2020)
– At Member State level
● One way to get there: open access
● Expected benefits:
– Better and more efficient science
– Economic growth
– Broader, faster, more transparent and equal access across
Europe for the benefit of researchers, industry and citizens
9. The Commission strategy
● Develop and implement open access to
research results from projects funded by the EU
Research Framework Programmes (FP7,
Horizon 2020)
– Incl. funding research and supporting activities in the
area of open access
● Encourage national initiatives at Member State
level
● Contribute to co-ordination between EU
Member States and beyond
10. Three key documents (16.07.2012)
● Communication 'A reinforced European
Research Area partnership for excellence and
growth'
● Communication 'Towards better access to
scientific information: boosting the benefits of
public investments in research'
● Recommendation on access to and
preservation of scientific information
12. Where to look?
– Regulation establishing Horizon 2020 (Art. 18)
– Specific Programme (Preamble 1.3)
– Rules for Participation (Art. 43)
– Work Programme 2014-15 (Introduction 1.5 and relevant areas)
– Model Grant Agreement (Art. 6.2.D.3, 29.2 and 29.3)
– Annotated Model Grant Agreement (reference to Guidelines
below)
– Guidelines on Open Access to Scientific Publications and
Research Data in Horizon 2020
– Guidelines on Data Management in Horizon 2020
13. Where???
The Participant Portal is the source of all
reference documents
http://ec.europa.eu/research/participants/portal/desktop/en/home.html
And OpenAIRE is here to help you!
15. Open access in Horizon 2020
Regulation establishing Horizon 2020
To increase the circulation and exploitation of knowledge,
open access to scientific publications should be ensured.
Furthermore, open access to research data resulting from
publicly funded research under Horizon 2020 should be
promoted, taking into account constraints pertaining to
privacy, national security and intellectual property rights,
Open access to scientific publications resulting from
publicly funded research under Horizon 2020 shall be
ensured [...].
Open access to research data resulting from publicly
funded research under Horizon 2020 shall be promoted.
16. From FP7 to H2020: OA to publications
FP7: the Pilot
● Green open access
pilot in 7 areas of
FP7 with 'best effort'
stipulation
● Allowed embargoes:
6/12 months
● Gold open access
costs eligible for
reimbursement as
part of the project
budget while the
project runs
H2020: Underlying principles
● Obligation to provide OA, either
through the Green or Gold way in
all areas
● Allowed embargoes: 6/12 months
● Gold open access costs eligible for
reimbursement as part of the project
budget while the project runs &
post-grant support being piloted
● Authors encouraged to retain
copyright and grant licences instead
17. OA to publications mandate in H2020
● Each beneficiary must ensure OA to all peer-
reviewed scientific publications relating to its
results:
– Deposit a machine-readable copy of the published version or
final peer-reviewed manuscript accepted for publication in a
repository of the researchers choice (possibly OpenAIRE
compliant)
– Ensure OA on publication or at the latest within 6/12 months
– Ensure OA to the bibliographic metadata that identify the
deposited publication, via the repository
– Aim to deposit at the same time the research data needed to
validate the results ("underlying data")
18. Pilot on Open Research Data in H2020
Three key questions:
● Which thematic
areas should be
covered?
● What kind of data
should be covered?
● What about data
management?
19. Pilot on Open Research Data in H2020
● Areas of the 2014-2015 Work Programme participating in the
Open Research Data Pilot are:
– Future and Emerging Technologies
– Research infrastructures – part e-Infrastructures
– Leadership in enabling and industrial technologies – Information and
Communication Technologies
– Societal Challenge: Secure, Clean and Efficient Energy – part Smart
cities and communities
– Societal Challenge: Climate Action, Environment, Resource Efficiency
and Raw materials – except raw materials
– Societal Challenge: Europe in a changing world – inclusive, innovative
and reflective Societies
– Science with and for Society
● Projects in other areas can opt-in on a voluntary basis.
20. Pilot on Open Research Data in H2020
● Projects can opt out of the Pilot on Open Research
Data in Horizon 2020 in a series of cases:
– If the project will not generate / collect any data
– Conflict with obligation to protect results
– Conflict with confidentiality obligations
– Conflict with security obligations
– Conflict with rules on protection of personal data
– If the achievement of the action’s main objective would be
jeopardised by making specific parts of the research data
openly accessible (to be explained in data management plan)
23. Pilot on Open Research Data in H2020
● Types of data concerned:
– Data needed to validate the results presented in scientific publications
("Underlying data")
– Other data as specified in the Data Management Plan (= up to
projects)
● Beneficiaries participating in the Pilot will:
– Deposit this data in a research data repository of their choice
– Take measures to make it possible to access, mine, exploit, reproduce
and disseminate free of charge
– Provide information about tools and instruments at the disposal of the
beneficiaries and necessary for validating the results (where possible,
provide the tools and instruments themselves)
● EC: Support & monitoring (Annotated MGA, Specific guidance
etc…)
24. Data management in Horizon 2020
● Data Management Plans (DMPs) mandatory for all
projects participating in the Pilot, optional for others
– DMPs are NOT part of the proposal evaluation, they need to be
generated within the first six months of the project and updated as
needed
– All proposers to submit general information on data management -
evaluated under criterion 'Impact'
● DMP questions:
– What data will be collected / generated?
– What standards will be used / how will metadata be generated?
– What data will be exploited? What data will be shared / made open?
– How will data be curated and preserved?
25. A chance to co-shape policy
● Opening up research data: the new frontier
● Ambitious, yet pragmatic design of the pilot: broad scope,
opt-out, voluntary participation possible
● Pilot is flexible: numerous safeguards are in place (incl.
opt-out during the project, if really necessary)
● Aim: kick-starting a virtuous circle
● Uptake of and experiences need to be monitored during
the complete life cycle of a project: from application, to
grant preparation, execution and final reporting
● Participating in the Pilot means co-shaping European
policy on opening up research data
26. ORD Pilot: initial take-up in first calls of
H2020
● Preliminary!
● Basis: 3054 Horizon 2020 proposals
– Calls in core-areas: opt out 24.2% (442 of
1824 proposals) – range from 9,1-29,1%
– Other areas: voluntary opt in 27.2% (334 of
1230 proposals) – range from 9 to 50%
● 'Early days' for the ORD Pilot, but initial
data on uptake in the proposals for the first
calls of Horizon 2020 are encouraging.
27. ORD Pilot: opt-out reasons among
proposals
19.62
24.68
6.96
23.41
4.43 6.7
no data generated
IPR protection
confidentiality
privacy
jeopardize main
objective
other
28. ORD Pilot: approach to data
management among proposals
44.2
49.23
6.9
data management plan
work package
other
29. Open research data: currently
ongoing…
● Analysis of uptake of the Pilot: in signed
grant agreements (versus proposals)
● Structure and coverage of the Pilot: to remain
the same, at least until mid-term review; small
incremental changes possible in 2016-17
● DMP implementation: investigating best-
practice; tools to be developed
● Monitoring of OA policies is crucial for further
policy development
31. Ongoing EU-funded projects
FOSTER (Foster Open Science Training for European Research)
Started 2014
PASTEUR4OA (Open Access Policy Alignment Strategies for
European Union Research) Started 2014
RECODE (Policy Recommendations for Open Access to Research
Data in Europe) – 2013, finishing
OpenAIRE/OpenAIRE+ supporting the implementation of Open
Access in Europe (publications and data)
New! FP7 post-grant Gold OA Pilot
Infrastructure projects (with OA components)
e.g. GEO/GEOSS, ELIXIR…
32. The international landscape
Study to measure the growth of OA
● Wide sample of 1 million records for in-depth study of between
2008 and 2013 (Focus on ERA, Brazil, Canada, Japan and USA)
● Global proportion higher than previously assumed:
– 55% of those published in 2012 are now free (adjusted for precision and recall)
– Quantity of Gold OA papers increasing by 18% per year
– Quantity of Green OA papers increasing by 8.8% per year
● OA papers were between 26% and 64% more cited on average
● Backfilling of papers is really important: about 700,000 papers from
1996-2011 became freely available between April 2013 and April
2014, the same quantity as those published 2013
source:
33. The international landscape
Study to measure the growth of OA
● OA availability varies among disciplines: 'tipping point' passed in
Biology, Biomedical Research, Mathematics & Statistics and in
General Science & Technology. Least open access in SSH, applied
sciences, engineering and technology
● The majority of 48 major science funders considers both Gold and
Green OA acceptable. More than 75% accepted embargo periods
of 6-12 months
● Policies for OA to data not as well developed but increasing
Working with international organisations (OECD, RDA, 'Berlin'
conferences and others)
34. In summary...
● Open access (OA) as part of a changing scientific system (Open
Science)
● OA as a means to improve knowledge circulation and provide
value for the taxpayers' money
● Horizon 2020 ambitious yet pragmatic on aspects of OA
– Open access to publications mandatory (Green or Gold)
– Limited pilot for open access to research data (opt-in/opt-out)
● Support from/for H2020: work programmes e-Infrastructure &
Science with and for Society
● OA must be effective, affordable, competitive and sustainable for
researchers and innovative businesses
35. Pointers
● Twitter: @OpenAccessEC
● Mail: RTD-open-access@ec.europa.eu
● Web: http://ec.europa.eu/research/swafs/
● Get support from
● Open Access with the