The document summarizes successes and challenges in rolling out antiretroviral therapy (ART) in low-income countries. Key successes include increasing ART access through lowered drug prices and expanded treatment guidelines by the WHO. However, challenges remain such as late treatment initiation leading to high mortality, low pediatric diagnosis rates, limited second-line treatment options, and loss to follow up. Ongoing efforts are needed to further scale up and improve ART programs.
This document summarizes arboviral surveillance activities in Georgia in 2009. It describes mosquito and dead bird surveillance programs, as well as reported cases of arboviral diseases in humans and animals. Surveillance data is used to monitor and predict disease transmission risk and inform public health responses like mosquito control activities. Collaboration between multiple state agencies and organizations helps provide a comprehensive picture of arboviral activity.
Fast-track the end of AIDS in the EU - practical evidence-based interventions.
Presentation by: Karen Champenois, Maison Blanche Hospital, Paris
In a two-day meeting under the auspices of the Maltese Presidency of the Council of the European Union (30-31 January 2017), HIV experts from across the European Union discussed how to reverse this trend and how to prepare Europe to achieve the set target of ending AIDS by 2030.
Gabriel Wagner, MD
Associate Clinical Professor
Division of Infectious Diseases & Global Public Health
Department of Medicine
University of California, San Diego
Laura Bamford, MD, MSCE
Associate Professor of Medicine
Medical Director, Owen Clinic
Division of Infectious Diseases and Global Public Health
Department of Medicine
University of California, San Diego
Edward Cachay, MD, MAS
Professor of Medicine
Division of Infectious Diseases & Global Public Health
Department of Medicine
University of California, San Diego
Fast-track the end of AIDS in the EU - practical evidence-based interventions.
Presentation by: Tonio Piscopo, Mater dei Hospital
In a two-day meeting under the auspices of the Maltese Presidency of the Council of the European Union (30-31 January 2017), HIV experts from across the European Union discussed how to reverse this trend and how to prepare Europe to achieve the set target of ending AIDS by 2030.
This document summarizes arboviral surveillance activities in Georgia in 2009. It describes mosquito and dead bird surveillance programs, as well as reported cases of arboviral diseases in humans and animals. Surveillance data is used to monitor and predict disease transmission risk and inform public health responses like mosquito control activities. Collaboration between multiple state agencies and organizations helps provide a comprehensive picture of arboviral activity.
Fast-track the end of AIDS in the EU - practical evidence-based interventions.
Presentation by: Karen Champenois, Maison Blanche Hospital, Paris
In a two-day meeting under the auspices of the Maltese Presidency of the Council of the European Union (30-31 January 2017), HIV experts from across the European Union discussed how to reverse this trend and how to prepare Europe to achieve the set target of ending AIDS by 2030.
Gabriel Wagner, MD
Associate Clinical Professor
Division of Infectious Diseases & Global Public Health
Department of Medicine
University of California, San Diego
Laura Bamford, MD, MSCE
Associate Professor of Medicine
Medical Director, Owen Clinic
Division of Infectious Diseases and Global Public Health
Department of Medicine
University of California, San Diego
Edward Cachay, MD, MAS
Professor of Medicine
Division of Infectious Diseases & Global Public Health
Department of Medicine
University of California, San Diego
Fast-track the end of AIDS in the EU - practical evidence-based interventions.
Presentation by: Tonio Piscopo, Mater dei Hospital
In a two-day meeting under the auspices of the Maltese Presidency of the Council of the European Union (30-31 January 2017), HIV experts from across the European Union discussed how to reverse this trend and how to prepare Europe to achieve the set target of ending AIDS by 2030.
Richard Garfein, PhD, MPH
Professor
Herbert Wertheim School of Public Health and Human Longevity Science
Adjunct Professor
Division of Infectious Disease and Global Public Health
Department of Medicine
University of California, San Diego
Fast-track the end of AIDS in the EU - practical evidence-based interventions.
Presentation by: Jean-Michel Molina, Assistance Publique Hôpitaux de Paris
In a two-day meeting under the auspices of the Maltese Presidency of the Council of the European Union (30-31 January 2017), HIV experts from across the European Union discussed how to reverse this trend and how to prepare Europe to achieve the set target of ending AIDS by 2030.
Meningococcal carriage in the African meningitis belt and the impact of MenAfriVac: an overview of the MenAfriCar project
http://www.meningitis.org/conference2015
Covid-19 in the United Kingdom: Impact on ethnic minority groupsAzeem Majeed
This document summarizes data from Public Health England and the Office of National Statistics on the impact of Covid-19 on ethnic minority groups in the UK. It finds that ethnic minority groups, particularly Black and South Asian individuals, experienced higher rates of Covid-19 diagnosis, hospitalization, and death. Socioeconomic factors like living conditions and occupation partially explain these differences, as do higher rates of pre-existing conditions. However, part of the increased risk remains unexplained even after accounting for other factors.
February 2010 Selected Zoonotic Diseases Conference Callgoa4
The document summarizes a conference call about dengue and zoonotic diseases. It discusses an update on dengue infections in the United States, including outbreaks in Texas, Hawaii and Florida. It also mentions a multistate outbreak of Salmonella infections linked to contact with aquatic frogs and recommendations provided to the public.
Fast-track the end of AIDS in the EU - practical evidence-based interventions.
Presentation by: Valerie Delpech, Public Health Engand
In a two-day meeting under the auspices of the Maltese Presidency of the Council of the European Union (30-31 January 2017), HIV experts from across the European Union discussed how to reverse this trend and how to prepare Europe to achieve the set target of ending AIDS by 2030.
This document discusses how telemedicine can help address challenges posed by the COVID-19 pandemic. It describes how telemedicine allows for efficient screening of patients through direct-to-consumer access to physicians via video calls or online intake forms. It also discusses how telemedicine can be used to monitor hospitalized patients remotely and allow specialists to consult on cases virtually. The barriers to increased telemedicine use include reimbursement policies, licensing issues, and the need for coordinated testing. However, health systems that already utilize telemedicine are well positioned to leverage these resources to treat COVID-19 patients while limiting exposure.
Fast-track the end of AIDS in the EU - practical evidence-based interventions.
Presentation by: Cary James, Terrence Higgins Trust
In a two-day meeting under the auspices of the Maltese Presidency of the Council of the European Union (30-31 January 2017), HIV experts from across the European Union discussed how to reverse this trend and how to prepare Europe to achieve the set target of ending AIDS by 2030.
Elliot Welford, MD
Infectious Diseases Fellow
Division of Infectious Diseases & Global Public Health
Department of Medicine
University of California, San Diego
David K. Robinson, Ph. D.Vice President, BiologicsHead and Executive Director, Biologics and Vaccines CMC RegulatoryMerck & Co, Inc.
Presenting on behalf of the International Federation of Pharmaceutical Manufacturers & Associations (IFPMA)WCBP CASS, Washington DC, USAJanuary 2014
Fast-track the end of AIDS in the EU - practical evidence-based interventions.
Presentation by: Amanda Mocroft, UCL
In a two-day meeting under the auspices of the Maltese Presidency of the Council of the European Union (30-31 January 2017), HIV experts from across the European Union discussed how to reverse this trend and how to prepare Europe to achieve the set target of ending AIDS by 2030.
This presentation summarizes research on cryptococcal antigen screening and treatment in resource-limited settings. It finds that screening individuals with CD4 counts <100 cells/uL and <200 cells/uL can reduce mortality, and point-of-care tests now enable screening in primary care clinics. Studies of simplified treatment regimens show promise, such as using high-dose liposomal amphotericin B for only 1-2 weeks. Field work in Mozambique demonstrated a 7.3% prevalence of cryptococcal antigenemia through screening at two clinics, and identified opportunities to improve care through expanded screening and ambulatory treatment models.
Jocelyn Keehner, MD
Infectious Disease Fellow
Division of Infectious Diseases & Global Public Health
Department of Medicine
University of California, San Diego
This document discusses different types of animal health surveillance systems. It describes passive surveillance as provider-initiated reporting, while active surveillance is health department-initiated. General surveillance collects data on multiple diseases, while targeted surveillance focuses on a specific disease. Data sources can include recorded diagnoses, clinical signs, survey reports, indirect indicators, and risk factors. Common surveillance systems are farmer-based, facility-based, sentinel, syndromic, and surveys. Each system has advantages and limitations for early detection and monitoring of animal diseases.
The status of the HIV Case Based Surveillance project in Uganda presented at the WHO Workshop to release and disseminate guidelines for Strengthening HIV Patient Monitoring Case Surveillance and Reporting
RISK FACTORS ASSOCIATED WITH SHEEPPOX AND GOATPOX SEROPREVALENCE AND IDENTIFI...EuFMD
This document summarizes a study on risk factors associated with sheeppox and goatpox virus exposure in northern Nigeria. The study aimed to assess virus prevalence across herds and identify factors linked to higher risk. Researchers found that 1.6% of sampled small ruminants had exposure to the viruses, with positive animals clustered in certain households and regions. Specifically, eastern Bauchi was identified as a high-risk area, while southwestern Bauchi and northwestern Plateau had lower risk. The results can help design targeted surveillance and intervention programs.
The National Audit of Meningitis Management (NAMM) analyzed data from 1,472 patients with bacterial or viral meningitis from 64 UK hospitals in 2017. The audit found that clinical care is not fully adhering to UK guidelines for meningitis management. Only 50% of patients had blood cultures taken within 1 hour of arrival and only 2% had a lumbar puncture within 1 hour. Adjunctive steroids were only given to 26% of patients. The audit results indicate there is significant room for improvement in adhering to guidelines regarding timely diagnostic testing, use of antibiotics and steroids, and meningitis management overall.
COPD research at NB-IRDT: Phase 1 Results from Canadian Community Health Su...DataNB
This document summarizes initial results from a COPD research project using Canadian Community Health Survey data linked to other New Brunswick health databases. A COPD working group comprised of administrators, clinicians, researchers and patients is utilizing these various data sources through the NB-IRDT platform. Preliminary findings show the prevalence of self-reported COPD increases with age, is higher among women in some health zones, and is associated with lower education levels and smoking status. The CCHS data provides a quick way to explore multiple risk factors but has limitations due to sample size and being unavailable annually.
Community Based DOTS - Mozambique_Dr. Paul RobinsonCORE Group
The mid-term evaluation of a community-based DOTS tuberculosis project in Mozambique found several accomplishments but also some challenges. Key results included an increase in the case notification rate and community knowledge about TB, along with a reduction in treatment by traditional healers and drug stock-outs. However, the case notification rate and quarterly supervision of health posts had declined. Constraints involved inaccurate recording of patients on community-based treatment and challenges retaining volunteers. The evaluation team acknowledged contributions from various partner organizations.
A person finds themselves in an unfamiliar place where others are trying to read their future and tell them they need surgery, causing them to panic and try to escape by running away and using a time machine to get to safety.
Richard Garfein, PhD, MPH
Professor
Herbert Wertheim School of Public Health and Human Longevity Science
Adjunct Professor
Division of Infectious Disease and Global Public Health
Department of Medicine
University of California, San Diego
Fast-track the end of AIDS in the EU - practical evidence-based interventions.
Presentation by: Jean-Michel Molina, Assistance Publique Hôpitaux de Paris
In a two-day meeting under the auspices of the Maltese Presidency of the Council of the European Union (30-31 January 2017), HIV experts from across the European Union discussed how to reverse this trend and how to prepare Europe to achieve the set target of ending AIDS by 2030.
Meningococcal carriage in the African meningitis belt and the impact of MenAfriVac: an overview of the MenAfriCar project
http://www.meningitis.org/conference2015
Covid-19 in the United Kingdom: Impact on ethnic minority groupsAzeem Majeed
This document summarizes data from Public Health England and the Office of National Statistics on the impact of Covid-19 on ethnic minority groups in the UK. It finds that ethnic minority groups, particularly Black and South Asian individuals, experienced higher rates of Covid-19 diagnosis, hospitalization, and death. Socioeconomic factors like living conditions and occupation partially explain these differences, as do higher rates of pre-existing conditions. However, part of the increased risk remains unexplained even after accounting for other factors.
February 2010 Selected Zoonotic Diseases Conference Callgoa4
The document summarizes a conference call about dengue and zoonotic diseases. It discusses an update on dengue infections in the United States, including outbreaks in Texas, Hawaii and Florida. It also mentions a multistate outbreak of Salmonella infections linked to contact with aquatic frogs and recommendations provided to the public.
Fast-track the end of AIDS in the EU - practical evidence-based interventions.
Presentation by: Valerie Delpech, Public Health Engand
In a two-day meeting under the auspices of the Maltese Presidency of the Council of the European Union (30-31 January 2017), HIV experts from across the European Union discussed how to reverse this trend and how to prepare Europe to achieve the set target of ending AIDS by 2030.
This document discusses how telemedicine can help address challenges posed by the COVID-19 pandemic. It describes how telemedicine allows for efficient screening of patients through direct-to-consumer access to physicians via video calls or online intake forms. It also discusses how telemedicine can be used to monitor hospitalized patients remotely and allow specialists to consult on cases virtually. The barriers to increased telemedicine use include reimbursement policies, licensing issues, and the need for coordinated testing. However, health systems that already utilize telemedicine are well positioned to leverage these resources to treat COVID-19 patients while limiting exposure.
Fast-track the end of AIDS in the EU - practical evidence-based interventions.
Presentation by: Cary James, Terrence Higgins Trust
In a two-day meeting under the auspices of the Maltese Presidency of the Council of the European Union (30-31 January 2017), HIV experts from across the European Union discussed how to reverse this trend and how to prepare Europe to achieve the set target of ending AIDS by 2030.
Elliot Welford, MD
Infectious Diseases Fellow
Division of Infectious Diseases & Global Public Health
Department of Medicine
University of California, San Diego
David K. Robinson, Ph. D.Vice President, BiologicsHead and Executive Director, Biologics and Vaccines CMC RegulatoryMerck & Co, Inc.
Presenting on behalf of the International Federation of Pharmaceutical Manufacturers & Associations (IFPMA)WCBP CASS, Washington DC, USAJanuary 2014
Fast-track the end of AIDS in the EU - practical evidence-based interventions.
Presentation by: Amanda Mocroft, UCL
In a two-day meeting under the auspices of the Maltese Presidency of the Council of the European Union (30-31 January 2017), HIV experts from across the European Union discussed how to reverse this trend and how to prepare Europe to achieve the set target of ending AIDS by 2030.
This presentation summarizes research on cryptococcal antigen screening and treatment in resource-limited settings. It finds that screening individuals with CD4 counts <100 cells/uL and <200 cells/uL can reduce mortality, and point-of-care tests now enable screening in primary care clinics. Studies of simplified treatment regimens show promise, such as using high-dose liposomal amphotericin B for only 1-2 weeks. Field work in Mozambique demonstrated a 7.3% prevalence of cryptococcal antigenemia through screening at two clinics, and identified opportunities to improve care through expanded screening and ambulatory treatment models.
Jocelyn Keehner, MD
Infectious Disease Fellow
Division of Infectious Diseases & Global Public Health
Department of Medicine
University of California, San Diego
This document discusses different types of animal health surveillance systems. It describes passive surveillance as provider-initiated reporting, while active surveillance is health department-initiated. General surveillance collects data on multiple diseases, while targeted surveillance focuses on a specific disease. Data sources can include recorded diagnoses, clinical signs, survey reports, indirect indicators, and risk factors. Common surveillance systems are farmer-based, facility-based, sentinel, syndromic, and surveys. Each system has advantages and limitations for early detection and monitoring of animal diseases.
The status of the HIV Case Based Surveillance project in Uganda presented at the WHO Workshop to release and disseminate guidelines for Strengthening HIV Patient Monitoring Case Surveillance and Reporting
RISK FACTORS ASSOCIATED WITH SHEEPPOX AND GOATPOX SEROPREVALENCE AND IDENTIFI...EuFMD
This document summarizes a study on risk factors associated with sheeppox and goatpox virus exposure in northern Nigeria. The study aimed to assess virus prevalence across herds and identify factors linked to higher risk. Researchers found that 1.6% of sampled small ruminants had exposure to the viruses, with positive animals clustered in certain households and regions. Specifically, eastern Bauchi was identified as a high-risk area, while southwestern Bauchi and northwestern Plateau had lower risk. The results can help design targeted surveillance and intervention programs.
The National Audit of Meningitis Management (NAMM) analyzed data from 1,472 patients with bacterial or viral meningitis from 64 UK hospitals in 2017. The audit found that clinical care is not fully adhering to UK guidelines for meningitis management. Only 50% of patients had blood cultures taken within 1 hour of arrival and only 2% had a lumbar puncture within 1 hour. Adjunctive steroids were only given to 26% of patients. The audit results indicate there is significant room for improvement in adhering to guidelines regarding timely diagnostic testing, use of antibiotics and steroids, and meningitis management overall.
COPD research at NB-IRDT: Phase 1 Results from Canadian Community Health Su...DataNB
This document summarizes initial results from a COPD research project using Canadian Community Health Survey data linked to other New Brunswick health databases. A COPD working group comprised of administrators, clinicians, researchers and patients is utilizing these various data sources through the NB-IRDT platform. Preliminary findings show the prevalence of self-reported COPD increases with age, is higher among women in some health zones, and is associated with lower education levels and smoking status. The CCHS data provides a quick way to explore multiple risk factors but has limitations due to sample size and being unavailable annually.
Community Based DOTS - Mozambique_Dr. Paul RobinsonCORE Group
The mid-term evaluation of a community-based DOTS tuberculosis project in Mozambique found several accomplishments but also some challenges. Key results included an increase in the case notification rate and community knowledge about TB, along with a reduction in treatment by traditional healers and drug stock-outs. However, the case notification rate and quarterly supervision of health posts had declined. Constraints involved inaccurate recording of patients on community-based treatment and challenges retaining volunteers. The evaluation team acknowledged contributions from various partner organizations.
A person finds themselves in an unfamiliar place where others are trying to read their future and tell them they need surgery, causing them to panic and try to escape by running away and using a time machine to get to safety.
This document is illegible and contains no discernible information. It appears to be random characters without any coherent words, sentences, or meaning. A proper summary cannot be generated from unintelligible text.
Kingston University Multimedia Production - Session 2: Layers of technologypetter
This document discusses digital media and its evolution through different technological layers and generations. It provides examples of typical web page components like HTML, CSS, images, and JavaScript. It also discusses different types of multimedia content like Flash movies, dynamic HTML, and web applications. The document encourages publishing an index.html page and provides contact information for the author.
This document provides specifications for a semester project on wireless technology. Students will work in teams to research and demonstrate proficiency in one of five wireless topics. Each team must create an informational blog and conduct a 15-20 minute demonstration of their assigned topic. Additionally, each student will independently summarize five recent journal papers related to their topic. The project aims to apply theoretical knowledge to practical scenarios and promote team-based and self-directed learning. Teams must register their topic by June 24th and complete all tasks by August dates to contribute to 20% of the overall course grade.
This document provides an overview of JavaScript and DOM for a lecture on internet programming. It outlines the objectives of understanding basic JavaScript concepts and the client-server model. The agenda covers what JavaScript is and why it is useful, where JavaScript code can be located, and how to process user input with DOM. It also gives examples of arithmetic operators in JavaScript and a simple cashier application example.
The document provides information on HIV/AIDS, including:
1. HIV was first identified in 1981 and there have been two major strains identified, HIV-1 and HIV-2.
2. HIV is transmitted through bodily fluids and can be transmitted sexually or through contact with infected blood.
3. There are three phases of HIV infection eventually resulting in AIDS if not treated. Antiretroviral treatment can suppress the virus and prevent AIDS.
MRC/info4africa KZN Community Forum | March 2012info4africa
Miss Dhirisha Naidoo - Clinical Manager of Male Medical Circumcision Programme at McCord Hospital spoke on the primary concepts related to prevention of infectious diseases, with a focus on Male Medical Circumcision (MMC). Based on the biological plausibility and epidemiological evidence, Miss Naidoo's presentation focused on the individual and public health benefits of Medical Male Circumcision (MMC). She also outlined the comprehensive programme based at McCord Hospital, and the challenges faced by the institution.
Fast-track the end of AIDS in the EU - practical evidence-based interventions.
Presentation by: Jens Lundgren, CHIP
In a two-day meeting under the auspices of the Maltese Presidency of the Council of the European Union (30-31 January 2017), HIV experts from across the European Union discussed how to reverse this trend and how to prepare Europe to achieve the set target of ending AIDS by 2030.
1) The document discusses strategies for ending tuberculosis (TB) through achieving the Sustainable Development Goals (SDGs) by 2030.
2) Key challenges include the high burden of drug-resistant TB and TB-HIV coinfections, as well as catastrophic costs that TB imposes on families in many countries.
3) Achieving universal health coverage, increasing funding for TB research and development, and developing new point-of-care diagnostics and more effective treatments are seen as critical to reducing the global TB burden.
The 18th International AIDS Conference (AIDS 2010)Abhishek Shah
The document summarizes key findings from the 18th International AIDS Conference held in Vienna, Austria in July 2010. Some of the main topics discussed include:
- The Vienna Declaration calling for decriminalization of drug use and scaling up HIV prevention and treatment services.
- Studies showing reduced HIV risk with male circumcision and use of tenofovir gel.
- Ongoing PrEP trials evaluating daily oral tenofovir for HIV prevention.
- Modeling suggesting universal HIV testing and treatment could reduce new infections and deaths in South Africa over 40 years.
This document summarizes the history and strategies of India's National AIDS Control Programme (NACP). It notes that HIV was first detected in India in 1986 among female sex workers in Chennai. In response, the government established an AIDS task force and initiated NACP in 1987 with World Bank support. NACP has since launched multiple phases (NACP I-IV) to expand targeted interventions for high-risk groups, increase testing and treatment, and reduce stigma. The current phase (NACP IV) aims to accelerate response efforts and integrate HIV services into the national health system from 2014-2017.
Acquired immunodeficiency syndrome (AIDS) is a chronic, potentially life-threatening condition caused by the human immunodeficiency virus (HIV). By damaging your immune system, HIV interferes with your body's ability to fight infection and disease.
The National AIDS Control Programme (NACP), launched in 1992, is being implemented as a comprehensive programme for prevention and control of HIV/AIDS in India. Over time, the focus has shifted from raising awareness to behavior change, from a national response to a more decentralized response and to increasing involvement of NGOs and networks of PLHIV.
Today we stand at a vital threshold. Within our grasp is the opportunity to end 30 years of suffering and death due to HIV/AIDS. Individuals and communities around the world have been mobilized toward prevention, and existing treatment can prolong life for many years. While we celebrate these successes, we reject any modicum of complacency. Now is the time to double down and finish the job. The world is fighting AIDS today just as it had previously fought to eliminate smallpox. For centuries, smallpox was a feared scourge that killed nearly half of those infected and maimed those that survived. A worldwide campaign to end the disease began in earnest in the late 1960s and by 1980 smallpox was officially eradicated.
Planet Aid anticipates the day when AIDS, too, will be stopped. To this end, we have been helping mobilize communities around the globe to increase HIV/AIDS prevention and care. With this special issue of the Planet Aid Post, we focus on the battle ahead. We also extend a warm welcome to those joining us on the forefront of this work,
Сравнение режимов лечения ВИЧ в разрезе различных клинических сценариев.ART...hivlifeinfo
This downloadable slideset summarizes optimal evidence-based antiretroviral therapy management strategies for a series of challenging clinical cases and is based on a satellite symposium presented at HIV Glasgow 2016.
Format: Microsoft PowerPoint (.ppt)
File size: 1.32 MB
Date posted: 11/11/2016
AIDSTAR-One Increasing Access to Prevention of Mother-to-Child Transmission S...AIDSTAROne
This technical report discusses the many services needed throughout the prevention of mother-to-child transmission (PMTCT) and infant care services continuum and identifies potential barriers to service coverage, access, and utilization. AIDSTAR-One provides examples of evidence-based and emerging practices to mitigate these barriers.
www.aidstar-one.com/focus_areas/pmtct/resources/report/increasing_access_to_pmtct_services
This document discusses HIV drug resistance monitoring in Indonesia. It provides background on the HIV epidemic in Indonesia, noting the first reported case in 1980 and rapid increase between 1990-2010. It describes the scale up of antiretroviral therapy (ART) starting in 2004-2005. It also discusses the establishment of the National Working Group on HIV Drug Resistance in 2005 and their key activities of monitoring early warning indicators and conducting HIV drug resistance surveys. Results of various drug resistance monitoring activities from 2004-2014 are presented, finding levels of transmitted drug resistance below 5%. Future plans for 2016-2019 include expanding early warning indicator monitoring, conducting additional drug resistance monitoring and surveys, and achieving WHO accreditation for the national HIV drug resistance genotyping
Professor Quarraisha Abdool Karim will take you on a journey showing how knowledge and science have made an incredible impact on battling the HIV virus on the African content. Through empowering women to help fight this deadly disease, Professor Karim’s work has managed to translate scientific research and knowledge into people-centred solutions and prevention programmes to reduce the factors making young people so vulnerable to HIV infection. Be inspired by this story and prepared to embrace your own challenges to transform them into positive actions.
This document summarizes the global burden of tuberculosis (TB) in 2011. Some key points:
- An estimated 1.4 million people died from TB that year, with over 80% of TB/HIV co-infections occurring in Africa.
- TB incidence rates were highest in Africa, linked to high HIV infection rates. People living with HIV are 20-40 times more likely to develop active TB.
- About 630,000 cases of multi-drug resistant TB were estimated, with over 60% occurring in 5 countries: India, China, Russia, Philippines, and Pakistan.
- 500,000 women and 65,000 children died from TB in 2011, and 10 million children were left orphaned
This document summarizes the challenges of HIV co-infections in the UK and strategies to address them. It finds that co-infections are a significant problem, especially among men who have sex with men and black communities. Improved surveillance, integrated care, and targeted public health interventions are needed to reduce co-infections in at-risk groups. Developing standardized monitoring indicators can help track progress in diagnosis, treatment, and prevention efforts going forward.
Can we end the HIV/AIDS epidemic? Josip begovacPinHealth
1) In 2013, 136,235 new HIV infections were diagnosed in Europe, with 79,728 infections in Russia alone.
2) The concept of "ending AIDS" refers to bringing the HIV epidemic under control through strategies like widespread antiretroviral treatment and prevention of onward transmission.
3) Studies have shown pre-exposure prophylaxis (PrEP) using antiretroviral drugs can reduce the risk of HIV transmission by over 80% when used consistently before and after exposure to the virus.
TB and HIV epidemics are closely linked, with each exacerbating the other. People with HIV are at much higher risk of developing active TB disease. TB is also a leading cause of death among people with HIV. Integrated and collaborative efforts are needed globally using the "Three I's" approach of intensified TB case finding, isoniazid preventive therapy, and infection control to reduce the burden of TB among people living with HIV and HIV among TB patients.
THE SACRIFICE HOW PRO-PALESTINE PROTESTS STUDENTS ARE SACRIFICING TO CHANGE T...indexPub
The recent surge in pro-Palestine student activism has prompted significant responses from universities, ranging from negotiations and divestment commitments to increased transparency about investments in companies supporting the war on Gaza. This activism has led to the cessation of student encampments but also highlighted the substantial sacrifices made by students, including academic disruptions and personal risks. The primary drivers of these protests are poor university administration, lack of transparency, and inadequate communication between officials and students. This study examines the profound emotional, psychological, and professional impacts on students engaged in pro-Palestine protests, focusing on Generation Z's (Gen-Z) activism dynamics. This paper explores the significant sacrifices made by these students and even the professors supporting the pro-Palestine movement, with a focus on recent global movements. Through an in-depth analysis of printed and electronic media, the study examines the impacts of these sacrifices on the academic and personal lives of those involved. The paper highlights examples from various universities, demonstrating student activism's long-term and short-term effects, including disciplinary actions, social backlash, and career implications. The researchers also explore the broader implications of student sacrifices. The findings reveal that these sacrifices are driven by a profound commitment to justice and human rights, and are influenced by the increasing availability of information, peer interactions, and personal convictions. The study also discusses the broader implications of this activism, comparing it to historical precedents and assessing its potential to influence policy and public opinion. The emotional and psychological toll on student activists is significant, but their sense of purpose and community support mitigates some of these challenges. However, the researchers call for acknowledging the broader Impact of these sacrifices on the future global movement of FreePalestine.
Elevate Your Nonprofit's Online Presence_ A Guide to Effective SEO Strategies...TechSoup
Whether you're new to SEO or looking to refine your existing strategies, this webinar will provide you with actionable insights and practical tips to elevate your nonprofit's online presence.
How Barcodes Can Be Leveraged Within Odoo 17Celine George
In this presentation, we will explore how barcodes can be leveraged within Odoo 17 to streamline our manufacturing processes. We will cover the configuration steps, how to utilize barcodes in different manufacturing scenarios, and the overall benefits of implementing this technology.
15. Total available resources for AIDS 1986-2008 13 billion 2008 [i] 1996-2005 data: Extracted from 2006 Report on the Global AIDS Epidemic (UNAIDS, 2006); [ii] 1986-1993 data: Mann.&. Tarantola, 1996 Notes : [1] 1986-2000 figures are for international funds only; [2] Domestic funds are included from 2001 onwards 0 1000 2000 3000 4000 5000 6000 7000 8000 9000 US$ million 292 1623 8.3 billion Signing of Declaration of Commitment on HIV/AIDS,UNGASS 1995 2000 2005 1987 1990 Less than US$ 1 million 59 212 World Bank MAP launch Global Fund PEPFAR 257 UNAIDS Gates Foundation 10 000 8.9 billion 10 billion 7.1 Source : UNAIDS & WHO unpublished estimates, 2007
23. Since 1996 the availability of effective treatment, has saved some 2.9 million lives…
24. Decline in TB incidence Source: Botswana MOH TB control program report to the Global Fund; mortality Central Statistical Office; ART, MOH; WHO, Botswana Triangulation 2005-6.
28. Late initiation of treatment in Sub-Saharan Africa leads to high initial mortality ART-LINC
29.
30. Early Mortality- The Case For early HIV Diagnosis and Care (community based ART program SA) SOURCE: S Lawn et al: AIDS; 22 : 1897–1908 (2008)
31.
32. Pediatric diagnosis and treatment 15% of HIV-exposed infants receive an HIV test within the two first months of life 28 % 28% of eligible children on ART
33. Use of simple 1 st and 2 nd line regimens AZT + 3TC + LPV/r TDF + 3TC or FTC + LPV/r TDF + 3TC or FTC + NVP AZT + 3TC + ATV/r TDF + 3TC or FTC + EFV AZT + 3TC + NVP TDF + 3TC or FTC + ATV/r AZT + 3TC + EFV Preferred 2 nd Line Options Preferred 1 st Line Options
34.
35. Very few patients are on second-line regimens in LMIC WHO 2010: Towards universal access: Scaling up priority HIV/AIDS interventions in the health sector
36. How do we suspect/diagnose treatment failure? VL>10,000 FIRST VL SECOND CD4 THIRD symptoms LATE DETECTION OF TREATMENT FAILURE Time Amount of CD4 or Amount of Virus ARV success ARV not success - Virus - CD4
38. 10 12 10 8 Report Setting WHO Criteria Sens % PPV % An et al. 2003 2006 2006 2006 30 20 24 27 21 17 17 33 Uganda Rwanda South Africa Meya et al. Van Griensven Mee, P. et al Cambodia
39. Using VL to better decide when to switch ART Two possible approaches… Targeted Viral Load Routine Viral Load To avoid unnecessary switching To detect early adherence problems
41. Coverage of TB services for PLWHIV, 2009, SSA 1000 new HIV cases ART eligible =44% Know HIV status =33% Screened for TB= 5% Incident TB in PLWHV=3% TB-ART=0.5% IPT=0.2% UNAIDS 2010, WHO Global TB report 2009 On ART = 16% 67% Does not know the HIV status
42. How many start ART? HIV Tested HIV-infected CD4/results Eligible for ART Start ART 2,775 1,467 605 368 154 (42%) Failure to obtain CD4 Failure to start ART when eligible Median time to ART initiation: 100 days Bassett et al. AIDS 2010 – slide from Walenski R
51. START ART EARLIER !! With better drugs… Viral load accessible Infant diagnosis Long term retention Community involvement Social support systems
52. Zambia, Fredrick Sinyinza START ART EARLIER !! The number of people estimated to be in need of antiretroviral therapy at the end of 2009 increased from 10.1 million to 14.6 million [13.5 million–15.8 million] WHO report 2010 Dear Lut, “ With the implementation of the new guidelines rolling out of ART is not without challenges. At one of the main sites, where I work, the number of pt starting HAART since we started using the new guidelines ( late sept this yr) has increased by 37% ( considering pts with WHO stage 1,2 and CD4 200-350)), as a result the clinic has become congested, the patients are complaining and the lab is complaining (too many specimens).”
53.
54. Patients (%) stratified by CD4 count soon after diagnosis (Swiss Cohort) M. Battegay, M. Rickenbach et al. 200 350
56. With better drugs… Second line ART is 10 x more expensive! Alternative first line ART is 3 x more expensive!
57.
58. At Front Lines, AIDS War Is Falling Apart By DONALD G. McNEIL Jr. Published: May 9, 2010 As the Need Grows, the Money for AIDS Runs Far Short By DONALD G. McNEIL Jr. Published: May 9, 2010
effective, convenient, and relatively nontoxic. ART regimens should be chosen in consideration of a patient’s particular clinical situation. Successful treatment is associated with durable suppression of HIV viremia over years, and consequently, ART reduces the risk
Virginia Hughes: Outlook for a Cure. Nature 15 July 2010
Massive increase in AIDS funding, especially after the UNGASS declaration in 2002, followed by the global fund and later by PEPFAR.
And treatment benefit became clear, the AIDS-related mortality began to decline in sub-Saharan Africa and the Caribbean in 2005. Different patterns have emerged in other regions. In North America and Western and Central Europe, deaths due to AIDS began to decline soon aſter antiretroviral therapy was introduced in 1996. And it is estimated that since 1996 the availability of ART has saved close to three million lives.
A community based program in South Africa shows the same effect
Opnieuw, gebrek aan virale lading mag geen obstakel vormen. Op basis van klinische en immunologische criteria kan je ook therapie falen vermoeden, … . vinden experts. Maar waar is de evidence?
Verschillende studies hebben aangetoond dat inderdaad de diagnostische accuraatheid van de WGO crioteria laag is. Niet alleen worden slecht 24-33% van de patiënten geïdentificeerd, maar bovendien is de PPV erg laag, wat leidt tot onnodig switchen naar een tweede lijnsbehandeling
Two OPD in Durban, PITC
Er zitten oon cohortes in met betalende patiëte
Parents and a younger daughter in Uganda have H.I.V. but only the daughter is eligible for drugs.
http://www.msf.org.uk/UploadedFiles/HIV_report_No_Time_To_Quit_May_2010_201005273105.pdf While the exceptional drive and resource mobilisation since 2001 allowed us to fight effectively against the HIV/AIDS epidemic over the past years, a sense of denial has set in among the donor community about this ongoing crisis. For the past year and a half, donors have increasingly voiced concern regarding the cost, sustainability and relative priority of HIV/ AIDS, against the background of an ostensible lack of funds.Access is about sufficient available treatment slots and ART sites distributed across the country. Today already, poorer patients cannot access the ARV lifeline, and rural areas in particular are underserved.In October 2010, a donor replenishment conference is planned to mobilize funds for the period 2011−2013. Donors have already requested the Global Fund to lower its financial ambitions. In 2009, the initial estimated needs were set at USD 20 billion for 2011-2013. In 2010, this estimate was revised down in the form of two additional scenarios, USD 13 or 17 billion respectively. All three scenarios inadequately reflect demand, as none include the additional resources required to implement the new WHO guidelines on earlier treatment and improved drug regimens. These funding levels will force rationing of treatment under Global Fund grants and accepting to support sub-standard treatment. In the Democratic Republic of Congo (DRC) 283,055 people are estimated to be in need of ART (as per the old WHO initiation criteria), but by the end of 2009, only 34,967 were reportedly on treatment - roughly 12% of the need. 44On top of the existing backlog of patients waiting for care, an estimated 179,000 more people will be become eligible for ART every year (as per old WHO criteria). In 2009, the Global Fund was supporting 1,000 new initiations per month. Now the revised availability of funds for initiation has been cut six-fold to 2,000 per year . The consequence is that in DRC – in spite of the acute crisis situation - dramatically fewer patients can start ARV. However, there is not yet unified donor support for earlier treatment with an improved first-line treatment regimen. For example, PEPFAR’s director has voiced reluctance towards implementing the new WHO treatment guidelines for earlier treatment. 52 This reluctance is translating into support of a lower standard of care in recipient countries. Most governments in the region simply cannot implement such a change without donor support
Padma TV, New Dehli: Despite lofty promises, many donor agencieshave not delivered. For example, the Global Fund to Fight AIDS, Tuberculosis and Malaria pledged US$10 billion a year when it was set up in 2001, but has delivered only US$3 billion a year so far. National governments are no better at fund- ing their AIDS programmes. At an April 2001 summit in Abuja, Nigeria, 52 African coun- tries pledged to allocate at least 15% of their national budgets for health. In 2007, only three (Botswana, Djibouti and Rwanda) were on track, and three others (Burkina Faso, Liberia and Malawi) had reached some targets. These slow and bureaucratic governmen These days, 92% of those receiving treatment in low- and middle-income countries take generic drugs made in India — the ‘pharmacy of the developing world’
ARV = drugs, ART = therapy = broader DPS (not MISAU, as requested by DPS)
ART = therapy, ARV = drugs 24% : report of MOH, end 2009 for central MBQ, more recent then national 31% of 2008