Despite occupying such an important part of the diagnostic and treatment process, lab professionals are considered to be among the most unrecognized healthcare workers — a hidden profession.
Academic Purposes Only
Despite occupying such an important part of the diagnostic and treatment process, lab professionals are considered to be among the most unrecognized healthcare workers — a hidden profession.
Academic Purposes Only
Speaker, Keynote: “A 'Talk' with Purpose,” McKesson Specialty Health's Annual Manufacturer Networking Evening (Invite only exclusive event), Chicago IL, May 31, 2018
I am a physician, clinical researcher, and educator. I am also on Twitter and tweet under the handle @EMARIANOMD. Naturally you may ask: “How does Twitter fit into a physician’s academic career?” These slides were part of an interactive workshop presented at the 2016 American Society of Anesthesiologists Annual Meeting "Social Media Bootcamp." Please see my blog http://www.edmariano.com/archives/926 for additional information.
Health Datapalooza IV: June 3rd-4th, 2013
Action Beats and Announcements
Patient-Centered Outcomes Research Institute (PCORI) Challenge Winners
PCORI challenged teams to develop a proposal or prototype for a patient/researcher ‘matching’ mechanism or system that can effectively connect potential partners interested in seeking funding for rigorous patient-centered outcomes research. Two winners will be announced.
Presenter: Anne Beal, Chief Operating Officer, Patient-Centered Outcomes Research Institute (PCORI)
HXR 2016: Tracking the Body: Devices, Consumer Genomics, and Sensors- Niall O...HxRefactored
As tracking has become more mainstream, consumers who were once only curious about their heart rate at the gym are now interested in diving deeper and learning more. This session takes a look at the technical side of the latest in telehealth solutions, genomic platforms, and hacks in the world of sensors and devices.
Precision medicine require high precision in all parts which contributes to it. This presentation outlines the methodologies and pin point a subsystem whose precision is lot to be desired.
Factors Important to Under-Represented Minority Applicants when Selecting an ...Zach Jarou
Background: In 2008, the Council of Emergency Medicine Residency Directors (CORD) assembled a panel of program directors (PDs), associate PDs, and emergency medicine (EM) faculty members to discuss the state of diversity in EM andto develop a set of “best practice” recruitment strategies designed to increase the number under-represented minorities (URMs) in EM residency training programs.
Objective: To evaluate the perceived importance of factors significant in influencing URM candidate residency program selection.
The Role of Patients & their Challenges in Clinical TrialsKathi Apostolidis
What are clinical trials
Myths about clinical trials
What patients want
The role of patients in clinical trials
How to communicate trial information
How to communicate trial results
Healthcare Innovation and Transformation - Dr. Ken YaleKen Yale
We are living in the greatest time in human history! People are living their lives on smartphones and apps, measuring themselves with wearable devices like the Apple Watch, and improving their health and care with advanced analytic algorithms. Healthcare is adopting AI, Machine Learning, and Deep Learning at an accelerated pace. “Healthcare is very important for people. We are democratizing it. We are taking what has been with the institutions, and empowering the individual to manage their health.
And we’re just getting started!” - Apple CEO Tim Cook, Jan 2019
Speaker, Keynote: “A 'Talk' with Purpose,” McKesson Specialty Health's Annual Manufacturer Networking Evening (Invite only exclusive event), Chicago IL, May 31, 2018
I am a physician, clinical researcher, and educator. I am also on Twitter and tweet under the handle @EMARIANOMD. Naturally you may ask: “How does Twitter fit into a physician’s academic career?” These slides were part of an interactive workshop presented at the 2016 American Society of Anesthesiologists Annual Meeting "Social Media Bootcamp." Please see my blog http://www.edmariano.com/archives/926 for additional information.
Health Datapalooza IV: June 3rd-4th, 2013
Action Beats and Announcements
Patient-Centered Outcomes Research Institute (PCORI) Challenge Winners
PCORI challenged teams to develop a proposal or prototype for a patient/researcher ‘matching’ mechanism or system that can effectively connect potential partners interested in seeking funding for rigorous patient-centered outcomes research. Two winners will be announced.
Presenter: Anne Beal, Chief Operating Officer, Patient-Centered Outcomes Research Institute (PCORI)
HXR 2016: Tracking the Body: Devices, Consumer Genomics, and Sensors- Niall O...HxRefactored
As tracking has become more mainstream, consumers who were once only curious about their heart rate at the gym are now interested in diving deeper and learning more. This session takes a look at the technical side of the latest in telehealth solutions, genomic platforms, and hacks in the world of sensors and devices.
Precision medicine require high precision in all parts which contributes to it. This presentation outlines the methodologies and pin point a subsystem whose precision is lot to be desired.
Factors Important to Under-Represented Minority Applicants when Selecting an ...Zach Jarou
Background: In 2008, the Council of Emergency Medicine Residency Directors (CORD) assembled a panel of program directors (PDs), associate PDs, and emergency medicine (EM) faculty members to discuss the state of diversity in EM andto develop a set of “best practice” recruitment strategies designed to increase the number under-represented minorities (URMs) in EM residency training programs.
Objective: To evaluate the perceived importance of factors significant in influencing URM candidate residency program selection.
The Role of Patients & their Challenges in Clinical TrialsKathi Apostolidis
What are clinical trials
Myths about clinical trials
What patients want
The role of patients in clinical trials
How to communicate trial information
How to communicate trial results
Healthcare Innovation and Transformation - Dr. Ken YaleKen Yale
We are living in the greatest time in human history! People are living their lives on smartphones and apps, measuring themselves with wearable devices like the Apple Watch, and improving their health and care with advanced analytic algorithms. Healthcare is adopting AI, Machine Learning, and Deep Learning at an accelerated pace. “Healthcare is very important for people. We are democratizing it. We are taking what has been with the institutions, and empowering the individual to manage their health.
And we’re just getting started!” - Apple CEO Tim Cook, Jan 2019
Are we ready for disruption in Translational Research through Digital Medicine?Ashish Atreja, MD, MPH
This is the slide deck that was presented at Translational Science 2016. Touches upon evidence generation as one of the most desired but expensive process in medical science. Provides examples of how Social Media, medical apps, quantified self movement are leading to patient generated data that can disrupt evidence generation process.
The e-patient: empowered or overwhelmed? Patient's perspective on new technol...jangeissler
"The e-patient: empowered or overwhelmed? Patient's perspective on new technologies", presented by Jan Geissler at EFGCP Annual Conference 2013 on "Virtual Future: Ethical dimensions of emerging technologies in clinical trials and research" on 29 January 2013 in Brussels
Role of Biostatistician and Biostatistical Programming in Epidemiological Stu...PEPGRA Healthcare
Pepgra experts provide regulatory biostatistics and epidemiology statistical programming support to all phases of clinical trial process development and commercialization. Our Epidemiological statistical services is are located globally & trained in current methods and standards to support the successful execution of your projects.
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MAKING SENSE OFSTATISTICSWhat statistics tell you an.docxsmile790243
MAKING SENSE OF
STATISTICS
What statistics tell
you and how to ask
the right questions.
Published in 2010
Making Sense of Testing: why scans and
health tests for well people aren’t always a
good idea
Making Sense of Screening: a guide to
weighing up the benefits and harms of
health screening programmes
Making Sense of radiation: a guide to
radiation and its health effects
Making Sense of Chemical Stories:
a briefing document for the lifestyle sector
on misconceptions about chemicals
Making Sense of gM: what is the genetic
modification of plants and why are scientists
doing it?
Making Sense of Weather & Climate: an
introduction to forecasts and predictions of
weather events and climate change
“I’ve got nothing to lose by trying it”: a
guide to weighing up claims about cures
and treatments
Science and Celebrities review
(2006, 2007, 2008)
Standing up for Science: a guide to the
media for early career scientists
Standing up for Science II: the nuts
and bolts
There goes the Science Bit... a hunt for
the evidence
“I don’t know what to believe”: a short guide
to peer review
Peer review and the Acceptance of New
Scientific Ideas
Other publications by Sense About Science
All are available as free downloads from www.senseaboutscience.org
Publications
Introduction
good statistics, bad statistics
Statistics are used to measure and make sense of the world. They
are produced by the Government, political parties, the civil service,
the Bank of England, opinion polls, campaign groups, social research,
scientific papers, newspapers and more. But when confronted with
stories such as “Crime rate rising again”, “Polls put Tories up to 7%
ahead”, “Child heart surgery halted at hospital after four deaths” or
“Swine flu ‘could kill up to 120m’”, how can we work out whether to
believe them and what they really mean?
Statistics can be hyped and sensationalised by the use of an extreme
value to make a story more dramatic or by reporting a relative
increase in risk without including the absolute change. Data may be
analysed and presented in different ways to support contradictory
arguments or to reach different conclusions, whether deliberately or
by mistake.
But while statistics can be misrepresented, they can also unpick
arguments. By knowing the right questions to ask we can discriminate
between the proper use of statistics and their misuse. We asked
statisticians, journalists and scientists to tell us how they make
sense of statistics and what pitfalls to look out for. They gave us the
following insights:
Statistics borrow from mathematics an air of precision and
certainty but also call on human judgment and so are subject to
bias and imprecision
Knowing what has been counted, and how, tells us whether a
study can really answer the question it addresses
Like words, numbers and statistics mean different things in
different contexts
Just because something is statistically significant it does ...
Non-invasive Diagnostic Tools: Cardiometabolic Risk Assessment and Predictionasclepiuspdfs
Cardiometabolic risks (CMRs) have rapidly increased to epidemic proportions worldwide in the past three decades. Cardiovascular disease (CVD) remains the number one killer. No country has reduced, reversed, or prevented the increase in the incidence or prevalence of chronic metabolic diseases. Framingham Heart Study group described the modifiable risk factors that promote the development of CVD. They also developed risk calculators, for the prediction of acute vascular events such as heart attacks and stroke. The risk predictor algorithms were fine-tuned, as and when additional risk factors were discovered. However, at the time of this writing, there is no such calculator for assessment, stratification, and management of CMRs. On the other hand, numbers of non-invasive diagnostic devices have been developed for continuous monitoring of blood pressure and glucose profiles. We have described in our earlier articles, non-invasive diagnostic platform developed by LD-Technologies,
V O L U M E 3 4 - N U M B E R 4 - F A L L 2 0 1 6 187FEATURE ART.docxkdennis3
V O L U M E 3 4 , N U M B E R 4 , F A L L 2 0 1 6 187
F E
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Nurse Practitioner Perceptions of a Diabetes Risk Assessment Tool in the Retail Clinic Setting Kristen L. Marjama, JoAnn S. Oliver, and Jennifer Hayes
Diabetes is the seventh leading cause of death in the United States, burdening society with
high costs for treatment and placing increased demand on the health care system (1). According to the 2014 National Diabetes Statistics Report, an estimated 29.1 million people in the United States have diabetes, and 8.1 million of them are undiagnosed (2). The lack of screening for early identification of patients at risk for type 2 diabetes is a significant clin- ical problem. Health care providers (HCPs) need to be aware of the in- creasing diabetes burden and to pri- oritize the screening of patients who may be at risk. Screening for risk can aid in both efforts to prevent the development of diabetes and early management of the disease to reduce complications. Clinical trials have demonstrated that type 2 diabetes can be delayed or prevented through life- style modification or pharmacother- apy for people at increased risk (3).
In order to reduce risk for those at risk of developing diabetes, screen- ing is a priority that will raise patient
awareness. Many patients are not aware of their risk for type 2 dia- betes until they receive a confirmed diagnosis from their HCP. There are numerous health care settings in which screenings can be imple- mented, including but not limited to primary care practices, urgent care centers, hospital emergency depart- ments, and retail health clinics.
Retail clinics are located in retail supermarket and pharmacy chains to provide high-quality, affordable, and easily accessible health care services for communities. A true measure of quality in retail clinics is their degree of adherence to several measures iden- tified in the Healthcare Effectiveness Data and Information Set (4). Services in this type of setting may include treatment of acute episodic conditions, physical examinations, vaccinations, health screenings, and prevention and management of chronic conditions (5). Retail clinics provide services to patients with or without insurance or a primary care “home.†Patients’ visits to a retail clinic afford the opportunity to assess
■IN BRIEF This article describes a study to gain insight into the utility and perceived feasibility of the American Diabetes Association’s Diabetes Risk Test (DRT) implemented by nurse practitioners (NPs) in the retail clinic setting. The DRT is intended for those without a known risk for diabetes. Researchers invited 1,097 NPs working in the retail clinics of a nationwide company to participate voluntarily in an online questionnaire. Of the 248 NPs who sent in complete responses, 114 (46%) indicated that they used the DRT in the clinic. Overall mean responses from these NPs indicated that they perceive the DRT as a feasible tool in the retail cli.
Take a look at the below link and then answer the below questions .docxssuserf9c51d
Take a look at the below link and then answer the below questions from each of their points of view:
Link: https://www.ted.com/talks/john_wilbanks_let_s_pool_our_medical_data/transcript?language=en
When you're getting medical treatment, or taking part in medical testing, privacy is important; strict laws limit what researchers can see and know about you. But what if your medical data could be used — anonymously — by anyone seeking to test a hypothesis? John Wilbanks wonders if the desire to protect our privacy is slowing research, and if opening up medical data could lead to a wave of health care innovation.
For this blog and tying all the topics covered in the class about the epistemology of knowledge, what is your opinion on this matter? Should we share or should we not share? To be or not to Be?
I want you to answer this from different points of view:
The Patient:
The Mother/Father/Son/Daughter/Husband/Wife/Partner/Friend who is trying to help:
The Doctor:
The Hospital Administrator:
The Researcher:
The Companies/Big Pharma:
The Government:
The Government Watchdogs making sure rules are enforced:
The Philanthropists:
He slammed the papers down on the table. "Doctor, I won't do it! I just saw on the news that the prostate blood test is useless at my age. It's milking the system." His face showed determination and defiance as his wife looked on in the corner. No amount of entreating could get him to budge on the subject. Forget the 10 years of my life I had sacrificed in the pursuit of medical knowledge, he had crowdsourced on Facebook information about the prostate specific antigen test; the difference is subtle, but I had gone to medical school and he had gone to Google. Posting information on their health and all their test results is a routine event for Friday Facebook users. Proclaiming quackery, he left my office determined never to return.
Patients want that aggregation of data. Appealing to their practical nature, the more data, the faster we get to a solution, and if it contributes to research and a better future, it can only be the right decision. Family and friends would likely agree, maintaining that in the best interest of the patient, posting data, even without the benefit of anonymity, is acceptable. As MIPS / MACRA move towards population management, more integrated metrics would be of great interest to the hospital administrator as well and allows for an understanding of which markets are likely to produce the best reimbursements by virtue of their higher baseline of health; not surprisingly, we know higher income demographics produce the most compliant patients with the best medical outcomes, which is why most hospitals now are closing shop in poor neighborhoods, despite their need, and opening up in upscale areas with not only an assured revenue stream of insured clients, but better access to medications for diabetes control, better access to nutrition which means faster and improved healing post-surgery, and lower l ...
Pharma challenges - Patient Centricity and Digital CapabilitiesJoana Santos Silva
Today pharma's business model is being challenged. The industry needs to rethink how it creates value. In particular, it needs to connect to patients and caregivers in a meaningful way. It many cases this connection can be guaranteed through digital tools and strategies. This presentation focuses on these challenges and showcases some best practices that are already available in the marketplace.
OSU Medical Center CEO Steven Gabbe, MD delivers a talk on facilitating learning healthcare systems: Focus on approaches to leverage Health IT investments for advancements in research and personalized healthcare and learning from every patient.
This session will focus on the usages of HIT to learn from every patient so that this knowledge can be used to further the practice of medicine. The discussion will address the implications for research, privacy, and HIT to change the paradigm of advancing healthcare discoveries so that it is a continuous process driven through every patient interaction.
Similar to Data explosion in medicine: challenges and opportunities (20)
This talk was given during the TIMPUYOG TALK SERIES: Integrating Social Media to Medical Practice #SocialMDs organized the UP College of Medicine Regionalization Students' Organization together with the Regionalization Program Committee held at the Buenafe Hall, College of Medicine, University of the Philippines Manila on November 15, 2019, Friday, 5:00 PM.
This presentation gave an overview on how social media can be used by medical trainees for professional development and networking.
Medical Breakthroughs from the "Baliw na Baliw sa (Biotechnology) Research"Ourlad Alzeus Tantengco
This talk was given during the pre-event Symposium on Biotechnology in Healthcare by the Food and Development Administration of the Philippines.
Almost all of the medical innovations (i.e. medicine, vaccines, diagnostic tests etc) that are available to us are products of years of basic science and clinical research. Medical innovations have resulted in improved health and quality of life worldwide. These medical breakthroughs do not happen overnight. They require years of research and discovery and a huge amount of financial support to fund research facilities and human resources. This talk will introduce the long process of how biotechnology research is translated into clinics and public health. Current medical biotechnology researches in the Philippines and abroad will also be discussed. Some of the current medical biotechnology researches being conducted in the Philippines include rapid dengue diagnostic kits, Philippine herbal medicines, and Filipino cardiovascular genetics. These researches continuously revolutionize healthcare in the Philippines. Likewise, groundbreaking biotechnology researches from all other countries also open up new treatment and prevention for different diseases such as HIV, cancer, and metastases. These researches continue to advance modern medicine to address health and development issues worldwide. Continuous partnership and collaboration among the academe, industry, and the government is crucial in supporting more medical biotechnology researches that will provide cheaper and more efficient diagnostics, vaccines and medicines.
This talk was given during the 2nd Academic Colloquium: Japan Academic Exchanges at the UP College of Medicine on October 10, 2019. I shared the my research experience at Osaka Women's and Children's Hospital. I also shared the research collaborations of other MD/PhD students with different Japanese institutions.
Communication has always been an integral part of the scientific endeavor. The work of a scientist will only be finished when it has been communicated. Social networks support both faster and more interactive ways of communicating Science to a wider audience. Twitter is among the most popular social networks at present, integrating a community of over 500 million users around the world. However, based on a 2014 survey, only 13% of 3,500 scientists worldwide actively visit Twitter.
Scientists can get a lot of benefits from using Twitter. It can be used for communicating research findings to the scientific community and to the public. Twitter allows users to follow Science influencers, to stay updated with research breakthroughs and opportunities, and to interact with other researchers. Twitter can also be helpful in research dissemination and readership. Previous studies have shown a strong association between science communication and citation rates. It also has a great potential to increase the reach of scientific messages and promote direct engagement with non-scientific audiences such as the public, media, policymakers, etc.
In today's world where there has been an alarming increase in anti-scientific trends and fake news, scientific voices are rapidly disappearing. Twitter is an excellent platform for scientists to craft a personal online brand to educate the public with evidence-based Science. To counter the perpetuation of fake news online, we need more scientists online who are willing to develop their own brands and to engage a generally bewildered populace.
This presentation will tackle the use of Twitter in Science communication, the benefits of using Twitter for researchers, and the steps on how scientists can maximize Twitter to advance their careers. Evidences showing the impact of Twitter in scientific production and dissemination, as well as networking and collaboration with other researchers will also be discussed.
This presentation was given during the orientation of the applicants of the MD-PhD in Molecular Medicine Program of the University of the Philippines College of Medicine. I shared in this presentation a glimpse of my life as an MD-PhD student.
I was invited by Adamson University Biology Society to give a talk about antimicrobial resistance during their Biocon 2018: Insights on the Latest Trends on Applied Biological Sciences in Ozanam AVR, Adamson University last February 22, 2018
This talk was given during their Summer Immersion Workshop 2018 in CH222, Calderon Hall last February 3, 2018. I was invited by the UP Regionalization Students Organization to give a talk about the different research regulatory bodies for the Regionalization Program students of UP College of Medicine.
I will share in this presentation my journey as an MD-PhD in Molecular Medicine student. Get to know the different things that I do inside and outside the medical school. Learn also how you can maximize your potential as a medical student / MD-PhD student.
Beginner's guide to establishing social media presence for health education2Ourlad Alzeus Tantengco
This presentation was given during the Track 2: Social Media in Medical Education of the 4th Philippine Healthcare and Social Media Summit 2018 in Grand Regal Hotel, Davao City, Philippines. This presentation talks about strategies in establishing Facebook page for health promotion and education.
This presentation was given during the Track 2: Social Media in Medical Education of the 4th Philippine Healthcare and Social Media Summit 2018 in Grand Regal Hotel, Davao City, Philippines. This presentation describes the use of different social media tools for undergraduate medical education and research.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
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Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
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Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Maxilla, Mandible & Hyoid Bone & Clinical Correlations by Dr. RIG.pptx
Data explosion in medicine: challenges and opportunities
1. Ourlad Alzeus G. Tantengco
MD-PhD Molecular Medicine Student (5th Year)
College of Medicine
University of the Philippines Manila
Email: ogtantengco@up.edu.ph
Presented at the 2nd UST SHS STEMP Camp "One STEM Forward: Vision 2050“. March 6, 2019
3. • 56/M known case of lung cancer,
Roman Catholic from Sta. Ana
Manila
• Chief Complaint: Weakness in the
left lower leg
• 1 month prior to admission, the
patient experienced weakness in
the left lower leg with associated
blurring of vision and headache.
Progression of symptoms
prompted consult at our
institution.
4. Imaging analytics are making algorithms that can analyze the pixel
and other bits and bytes of data contained within the image to
detect the distinct patterns associated with a pathology.
7. Densen P. 2011. Challenges and Opportunities Facing Medical Education. Transactions of the American Clinical and Climatological Association. 122: 48-58
8.
9.
10.
11.
12.
13.
14.
15.
16. Source: Rumsfield et al. 2016. Big data analytics to improve cardiovascular care: promise and challenges. Nat Rev Cardiol.;13(6):350-9
17. Source: Greene SM, Reid RJ, Larson EB.2012. Implementing the learning health system: from concept to action. Ann Inter Med;157:207-10
21. Source: Healthcare Data Institute. 2015. Unlocking the full potential of data analytics for the benefit of all. 21, Rue Jasmin 75016 Paris, France.
22. • Significantly improve decision-making on
the design of the right treatment
protocols and the choice of adequate
treatment for a given patient
• Help assess and understand healthcare
needs in a given location
Source: Healthcare Data Institute. 2015. Unlocking the full potential of data analytics for the benefit of all. 21, Rue Jasmin 75016 Paris, France.
23. • Improving early diagnostics by pooling
information to identify new biomarkers
• Refining the understanding of chronic
pathologies
• Accelerating the discovery and
development of new drugs and therapies,
at every stage of the R&D process
Source: Healthcare Data Institute. 2015. Unlocking the full potential of data analytics for the benefit of all. 21, Rue Jasmin 75016 Paris, France.
24. • Facilitating drug/ device evaluation
• Enabling the development of personalized
medicine
• Fostering the emergence of a new era of
data-assisted decision-making
Source: Healthcare Data Institute. 2015. Unlocking the full potential of data analytics for the benefit of all. 21, Rue Jasmin 75016 Paris, France.
25. • Evaluating health status of the population and
informing the planning and reconfiguration of
healthcare services
• Improving detection and interpretation of early/
weak signals in public health surveillance
Source: Healthcare Data Institute. 2015. Unlocking the full potential of data analytics for the benefit of all. 21, Rue Jasmin 75016 Paris, France.
26. Source: Rumsfield et al. 2016. Big data analytics to improve cardiovascular care: promise and challenges. Nat Rev Cardiol.;13(6):350-9
31. Source: Byyny RL. 2012. The data deluge: the information explosion in medicine and science. Pharos Alpha Omega Alpha Honor Med Soc.;75(2):2-5.
32. …the conscientious, explicit, and judicious use
of current best evidence in making decisions
about the care of individual patients (Sacket,
2006).
…systematic approach to clinical problem
solving which allows the integration of the
best available research evidence with clinical
expertise and patient values (Sacket, 2000).
…a systematic approach to acquisition,
appraisal and application of research
evidence to guide decisions in healthcare
(Dans, 2008).
36. Physicians and other
scientists are good and
getting better at producing
data. But we must become
proficient—with or without
the help of technology—at
mining and managing the
data in ways that will allow
us to use it to maximum
effect. - Richard L. Byyny, MD,
FACP