This document is a final report for the Advanced Radio Transmission Experimental Michigan Satellite (ARTEMIS) project. It provides an overview of the mission requirements and design drivers for the subsystems of the ARTEMIS CubeSat. The report describes the preliminary analyses and simulation tools used to evaluate the performance of the satellite's orbits, communication system, propulsion system, electrical power system, attitude determination and control system, command and data handling system, structures, thermal control system, and guidance system.