Kapital Business Partners Temmuz 2010 TRShinesquad
Kapital, özellikle gelişmekte olan uluslararası firmalara, bağımsız denetim, vergi danışmanlığı, muhasebe hizmetleri, KDV iadesi raporları, kurumsal finansman danışmanlığı, transfer fiyatlandırması, hukuk hizmetleri, iç kontrol, adli denetim hizmetleri ve IT denetimleri yapan mali odaklı, profesyonel iş hizmetleri sağlayıcısıdır.
Kapital Business Partners Temmuz 2010 TRShinesquad
Kapital, özellikle gelişmekte olan uluslararası firmalara, bağımsız denetim, vergi danışmanlığı, muhasebe hizmetleri, KDV iadesi raporları, kurumsal finansman danışmanlığı, transfer fiyatlandırması, hukuk hizmetleri, iç kontrol, adli denetim hizmetleri ve IT denetimleri yapan mali odaklı, profesyonel iş hizmetleri sağlayıcısıdır.
In our second session we began the first half of our language crash course. This session covered Classes vs. Objects, Duck Typing, Variables, Strings and Methods.
This slide set identifies some of the crucial intersections of ethical tensions. It was designed to help generate discussions related to essential ethical questions.
This five step process utilizes strategi analysis tools to help students better understand their personal and professional development challenges after graduation.
Deborah Masucci, Chair of the Board of the International Mediation Institute and former VP at AIG, describers her personal experience of bringing mediation and ADR to the fore in dispute resolution. The presentation was in London in October 2014 to an invited audience hosted by Trust Mediation and Expedite Resolution, two leading UK based mediation providers.
In our second session we began the first half of our language crash course. This session covered Classes vs. Objects, Duck Typing, Variables, Strings and Methods.
This slide set identifies some of the crucial intersections of ethical tensions. It was designed to help generate discussions related to essential ethical questions.
This five step process utilizes strategi analysis tools to help students better understand their personal and professional development challenges after graduation.
Deborah Masucci, Chair of the Board of the International Mediation Institute and former VP at AIG, describers her personal experience of bringing mediation and ADR to the fore in dispute resolution. The presentation was in London in October 2014 to an invited audience hosted by Trust Mediation and Expedite Resolution, two leading UK based mediation providers.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
In India, pharmacovigilance activities are monitored by the Pharmacovigilance Programme of India (PvPI), which works closely with CDSCO to collect, analyze, and act upon data regarding adverse drug reactions (ADRs). Together, they play a critical role in ensuring that the benefits of drugs outweigh their risks, maintaining high standards of patient safety, and promoting the rational use of medicines.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
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It is not the strongest of the species
that survives, nor the most intelligent,
but the one most responsive to change.”
A thought to start with...
Charles Darwin, ‘The Origin of the Species’
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Wikipedia says…
• Creativity is a mental and
social process involving the
generation of new ideas or
concepts, or new
associations of the creative
mind between existing ideas
or concepts.
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Starting from any point, draw four continuous
lines (without lifting the pen) so that each of the
nine dots has at least one line running through
it.
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Hard questions
• Why are we not able to
think creatively?
• What are the stumbling
blocks
• Effects in the classroom
of not being creative
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MENTAL BLOCK # 7
Don’t be foolish.
How many times
have you laughed
at a student who
has given a
presumably
wrong answer?
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MENTAL BLOCK # 8
You should not make mistakes
• Punishment
for making
mistakes?
• Good decisions come from
Experience, and experience comes
from Bad decisions!!!
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Have a look at the picture below. It shows a person
holding a block of wood. Now, what will happen to the
piece of wood when the person lets go of it?
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Closing notes…
• “When in doubt, make a fool of yourself. There is a
microscopically thin line between being brilliantly creative
and acting like the most gigantic idiot on earth. So what the
hell, leap.”
Throughout our school years, we have all been taught to look for the “right answer”. What happens is that if we think there is only one “right” answer, then we will stop looking as soon as we find it. Our creative thinking process stops with that one “right answer.” When we allow ourselves to use our imagination, we are able to discover many answers.
For example: Tests in schools that are multiple choice and true/false questions look for only one right answer.
We have been taught throughout life to look at things as right or wrong, as works or does not work or as black or white. That type of logic implies that there is a definite right and wrong answer. We often do not look at the gray because it is not logical. That is really a shame because looking at the gray can be playful, funny, and creative.
When we think only of what is right or wrong or black or white, our focus may be so narrow that we miss out on some good ideas.
For Example: What do a cat and a refrigerator have in common?. Logical thinking would say NOTHING. However, creative thinking may see a number of things a cat and a refrigerator have in common:
they both have a place to put fish,
they both have tails,
they both come in a variety of colors,
they both purr,
they both have a lifetime of about fifteen years, etc.
We are under a lot of pressure to “follow the rules.” We are taught this from the time we are children.
Often, challenging the rules is good creative thinking strategy. Also, if we never challenge the rules, we may get locked into one approach or method without seeing other approaches that may also work.
For Example: Every night at the dinner table, Jane sits next to her mother. From the time Jane was a baby and began to eat food she was seated next to her mother so that it was convenient for her mother to feed her. Well, Jane is a young adult who no longer needs her mother’s assistance; however, her assigned seat remains next to her mother.
We so often focus on what is practical, on what we already know works. When people look at new ideas, they tend to be critical and focus on what is out of the ordinary. Often the comments made are negative, for instance, “that won’t work.” We have been trained to respond to the unusual by saying “that’s not practical”, instead of “hey, that sounds like a neat idea.”
For Example: Just imagine the creative ideas we would have if we were to look at the way things were and asked “what if”, “what if we did it differently.” “What if we only went to work three days a week and did the rest of the work at home?” “What if we ate dinner for breakfast and breakfast for dinner?”
Ask the question - “When do you get your best ideas?” Some people will respond by saying:
“When I have a problem.”
“When something breaks down, and I have to fix it.”
“When I have a deadline.”
These are common responses and are quite acceptable to most people.
These types of responses indicate that we are creative when it is necessary for us to be creative.
The type of work people do is becoming more and more specialized. Our focus is becoming more narrow. For instance, the days of an auto mechanic working on all kinds of cars are gone. Auto mechanics typically specialize on one type of car, for instance Japanese cars or BMW’s or Fords. Well, with specialization, people begin to think they do not have anything to offer outside their area of specialization.
It is important to realize that very few problems are related to just one area. Most problems are related to many different areas. Just because it is not our area, does not mean that we don’t have something to offer.
For Example: Think of yourself as an explorer. Wherever you go, there are new ideas waiting for you to discover.
We have learned that the best way to get along is to go along with the crowd. We tend to conform so that we do not look foolish. If you don’t conform, you might look like you don’t know what you are doing.
The problem is that when we try to conform with our thinking, we end up thinking like everyone else. Our creativity and imagination gets stifled. We begin to look at an idea in the same way.
For Example: To be creative, sometimes we have to take a risk and allow ourselves to look at things differently. Try it, you just may find that people appreciate another viewpoint and that your creative idea may help someone out.
Many people are not comfortable with errors. Our educational system has taught us to look for the “right answers”. From an early age, we are taught that right answers are good and incorrect answers are bad. From this, we learn to be right as often as possible, to make as few mistakes as possible. In other words, we learn that “to err is wrong.”
The sad part of this line of thinking is that it does not allow us to learn from our mistakes. When we do not allow ourselves to make mistakes, we are not allowing ourselves to think creatively. Mistakes are not bad, they are a learning experience. At the very least, we learn what does not work and from there, we very well may learn what does work.
Errors are a sign that you are breaking new ground and are trying new things. Remember, if you fail you learn what doesn’t work. The failure gives you an opportunity to try a new approach.
For Example: The comedian and film director Woody Allen once said, “If you are not failing every now and again, it’s a sign you’re not trying anything very innovative.”
If we see ourselves as not creative, then we will not be creative. People who do not think they are creative never put themselves in a position where they can use their creativity. Because they do not think they are creative, their creativity stays locked away.
For Example: A major difference between creative people and lesser creative people is that creative people give themselves a chance to pay attention to their ideas. They allow themselves to play with their small ideas. Even is the idea is small, they know that a small idea may lead to a big breakthrough and they believe that they are capable of making it happen.