#Aptamer is a term derived from the Latin aptus - fit, and the Greek meros – part. #Aptamers are oligonucleic acid or peptide molecules that bind to a specific target molecule.

2. Definition
 Aptamer is a term derived from the Latin aptus - fit, and the
Greek meros – part. Aptamers are oligonucleic
acid or peptide molecules that bind to a specific target molecule. By
selecting from a large random sequence pool, we usually can get
aptamers, but natural aptamers also are found in riboswitches. To
narrow down, aptamers can be classified as:
 DNA or RNA or XNA aptamers. They consist of (usually short)
strands of oligonucleotides.
 Peptide aptamers. They consist of a short variable peptide domain,
attached at both ends to a protein scaffold.

3. Applications
 Aptamers can be used for both basic research and clinical
purposes as macromolecular drugs. Aptamers can be
combined with ribozymes to self-cleave in the presence of
their target molecule. These compound molecules have
additional research, industrial and clinical applications.

4. Features
 Aptamers can bind to pre-selected targets, including proteins and peptides
with high affinity and specificity and unlike actual genetic material, their
specificity and characteristics are not directly determined by their primary
sequence, but instead by their tertiary structure. And compared to antibodies,
some aptamers exhibit stereoselectivity. Some aptamers (synthetic antibodies)
have been generated that exhibit greater than 10,000-fold binding affinity for
theophylline over caffeine, which differ from one another in structure by only
a single methyl group.
 The picture shows a structure of aptamer

5.  For sensors, therapeutic tools, cellular process regulation, as well as
guiding drugs to their specific cellular targets, aptamers can help.
 Aptamer Supplier
 Aptamer services provided by Creative Biogene include:
 Aptamer synthesis
 Aptamer generation
 Cell SELEX
 Aptamer design and modification
 Other services: negative selection (By means of negative selection
techniques non-specific binders will be removed), aptamer-based
precipitation, aptamer-based sensors and aptamer-based microarrays,
allosteric/structure-switching aptamer.

6. About Creative Biogene
 Creative Biogene is a US-based
manufacturer and provider of genomics and
proteomics products and services for
academic and governmental research
institutes, pharmaceutical and
biotechnology industry.

7. Contact to Inquiry
 USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Email：info@creative-biogene.com
United Kingdom
St John's Innovation Centre, Cowley Road, Cambridge
CB4 0WS, UK
Tel: 44-207-048-3343
Email：info@creative-biogene.com
 Web: http://www.creative-biogene.
com/Services/Aptamers/Aptamers-Services.html