This document discusses heat transfer via convection. It defines the basic types of heat transfer and distinguishes between natural and forced convection. Natural convection occurs due to density differences in a fluid caused by temperature gradients, without an external source of motion. Forced convection uses an external source like a fan or pump to enhance fluid motion and heat transfer. The document also examines factors that affect the convective heat transfer coefficient and introduces the Nusselt and Prandtl numbers in analyzing dimensional relationships of natural convection.
Heat transfer due to emission of electromagnetic waves is known as thermal radiation. Heat transfer through radiation takes place in form of electromagnetic waves mainly in the infrared region. Radiation emitted by a body is a consequence of thermal agitation of its composing molecules. The underlying mechanisms and the concepts involved are discussed in the ppt
heat conduction and its mechanisms ,thermal conductivity,Fourier law,variation of thermal conductivity with temperature in metals and solids,steady and unsteady states,biot and Fourier numbers and their significance, Lumped heat analysis
Heat transfer due to emission of electromagnetic waves is known as thermal radiation. Heat transfer through radiation takes place in form of electromagnetic waves mainly in the infrared region. Radiation emitted by a body is a consequence of thermal agitation of its composing molecules. The underlying mechanisms and the concepts involved are discussed in the ppt
heat conduction and its mechanisms ,thermal conductivity,Fourier law,variation of thermal conductivity with temperature in metals and solids,steady and unsteady states,biot and Fourier numbers and their significance, Lumped heat analysis
Understand the physical mechanism of convection and its classification.
Visualize the development of velocity and thermal boundary layers during flow over surfaces.
Gain a working knowledge of the dimensionless Reynolds, Prandtl, and Nusselt numbers.
Distinguish between laminar and turbulent flows, and gain an understanding of the mechanisms of momentum and heat transfer in turbulent flow.
Derive the differential equations that govern convection on the basis of mass, momentum, and energy balances, and solve these equations for some simple cases such as laminar flow over a flat plate.
Non dimensionalize the convection equations and obtain the functional forms of friction and heat transfer coefficients.
Use analogies between momentum and heat transfer, and determine heat transfer coefficient from knowledge of friction coefficient.
1. What is Heat Transfer?
2. APPLICATIONS OF HEAT TRANSFER
3. MODES OF HEAT TRANSFER
4. CONDUCTION
5. Fourier’s law of heat conduction
6. CONVECTION
7. Newton’s law of cooling
8. RADIATION
9. Stefan–Boltzmann law
Learn about Conduction, Convection, Radiation and Heat exchangers in a most comprehensive and interactive way. Derivations of formulas, concepts, Numerical, examples are inculcated in the course with advance applications. The course aims at covering all the topics and concepts of HMT as per academics of students. Following are the topics (in detail) that will be covered in the course.
Conduction
Thermal conductivity, Heat conduction in gases, Interpretation Of Fourier's law, Electrical analogy of heat transfer, Critical radius of insulation, Heat generation in a slab and cylinder, Fins, Unsteady/Transient conduction.
Convection
Forced convection heat transfer, Reynold’s Number, Prandtl Number, Nusselt Number, Incompressible flow over flat surface, HBL, TBL, Forced convection in flow through pipes and ducts, Free/Natural convection.
Heat Exchangers
Types of heat exchangers, First law of thermodynamics, Classification of heat exchangers, LMTD for parallel and counter flow, NTU, Fouling factor.
Radiation
Absorbtivity, Reflectivity, Transmitivity, Laws of thermal radiation, Shape factor, Radiation heat exchange
COPY-PASTE below URL to ENROLL in the COMPLETE course & see the hidden contents with proper explanations.
https://www.udemy.com/course/heat-and-mass-transfer
Lectures on Heat Transfer - Introduction - Applications - Fundamentals - Gove...tmuliya
This file contains Introduction to Heat Transfer and Fundamental laws governing heat transfer.
The slides were prepared while teaching Heat Transfer course to the M.Tech. students in Mechanical Engineering Dept. of St. Joseph Engineering College, Vamanjoor, Mangalore, India.
Understand the physical mechanism of convection and its classification.
Visualize the development of velocity and thermal boundary layers during flow over surfaces.
Gain a working knowledge of the dimensionless Reynolds, Prandtl, and Nusselt numbers.
Distinguish between laminar and turbulent flows, and gain an understanding of the mechanisms of momentum and heat transfer in turbulent flow.
Derive the differential equations that govern convection on the basis of mass, momentum, and energy balances, and solve these equations for some simple cases such as laminar flow over a flat plate.
Non dimensionalize the convection equations and obtain the functional forms of friction and heat transfer coefficients.
Use analogies between momentum and heat transfer, and determine heat transfer coefficient from knowledge of friction coefficient.
1. What is Heat Transfer?
2. APPLICATIONS OF HEAT TRANSFER
3. MODES OF HEAT TRANSFER
4. CONDUCTION
5. Fourier’s law of heat conduction
6. CONVECTION
7. Newton’s law of cooling
8. RADIATION
9. Stefan–Boltzmann law
Learn about Conduction, Convection, Radiation and Heat exchangers in a most comprehensive and interactive way. Derivations of formulas, concepts, Numerical, examples are inculcated in the course with advance applications. The course aims at covering all the topics and concepts of HMT as per academics of students. Following are the topics (in detail) that will be covered in the course.
Conduction
Thermal conductivity, Heat conduction in gases, Interpretation Of Fourier's law, Electrical analogy of heat transfer, Critical radius of insulation, Heat generation in a slab and cylinder, Fins, Unsteady/Transient conduction.
Convection
Forced convection heat transfer, Reynold’s Number, Prandtl Number, Nusselt Number, Incompressible flow over flat surface, HBL, TBL, Forced convection in flow through pipes and ducts, Free/Natural convection.
Heat Exchangers
Types of heat exchangers, First law of thermodynamics, Classification of heat exchangers, LMTD for parallel and counter flow, NTU, Fouling factor.
Radiation
Absorbtivity, Reflectivity, Transmitivity, Laws of thermal radiation, Shape factor, Radiation heat exchange
COPY-PASTE below URL to ENROLL in the COMPLETE course & see the hidden contents with proper explanations.
https://www.udemy.com/course/heat-and-mass-transfer
Lectures on Heat Transfer - Introduction - Applications - Fundamentals - Gove...tmuliya
This file contains Introduction to Heat Transfer and Fundamental laws governing heat transfer.
The slides were prepared while teaching Heat Transfer course to the M.Tech. students in Mechanical Engineering Dept. of St. Joseph Engineering College, Vamanjoor, Mangalore, India.
Introduction to Heat Transfer Mechanism.pptxhublikarsn
Heat transfer is the fundamental process by which thermal energy is exchanged between different materials or systems. This introduction explores the key concepts that govern the movement of heat, setting the stage for a deeper understanding of thermal systems and their applications.
Modes of Heat Transfer Conduction :Atomic Vibrations
In conduction, heat is transferred through the vibration of atoms and molecules within a material
Temperature Gradient
Conduction occurs due to a temperature gradient, where heat flows from the hotter region to the cooler region.
Thermal Conductivity
The rate of conduction depends on the material's thermal conductivity, which varies based on the atomic structure.
Convection:Fluid Motion
Heat is transferred by the movement of a fluid, such as air or water, over a surface
Natural Convection
Heat is transferred by the movement of a fluid, such as air or water, over a surface.
Forced Convection
Fluid motion is driven by an external force, such as a fan or pump
Radiation: Electromagnetic Waves
Heat is transferred through the emission and absorption of electromagnetic waves, even in a vacuum.
No Medium Required
Radiation can transfer heat even in a vacuum, unlike conduction and convection.
Emissive Power
The rate of radiation heat transfer depends on the emissive power of the surface.
Fourier's Law
Heat conduction is proportional to the temperature gradient and the material's thermal conductivity.
Newton's Law of Cooling
The rate of convective heat transfer is proportional to the temperature difference between the surface and the fluid.
Stefan-Boltzmann Law
The rate of radiative heat transfer is proportional to the fourth power of the absolute temperature.
Thermal contact resistance is the resistance to heat flow at the interface between two materials in contact. It arises due to surface irregularities and imperfect mating of the surfaces.
Accounting for thermal contact resistance is crucial in the design of efficient heat transfer systems, such as heat exchangers and electronic cooling applications
Contact pressure, surface roughness, and the presence of interfacial materials (e.g., thermal grease) can all influence the thermal contact resistance.
The critical radius of insulation is the thickness of insulation at which the heat loss from an insulated pipe or cylinder is minimized.
Knowing the critical radius is important for optimizing the insulation design to achieve maximum efficiency and cost-effectiveness.
The critical radius depends on the thermal conductivity of the insulation and the surrounding medium.
Heat transfer can be analogous to electrical circuits, with temperatures and heat fluxes corresponding to voltages and currents, respectively. This analogy helps in the analysis and design of thermal systems.
The overall heat transfer coefficient (U) is a measure of the overall effectiveness of heat transfer between a fluid and a solid surface. It accounts for various modes of heat transfer, such as conduction, c
Heat exchangers are devices that transfer heat from one medium to another. The purpose of the heat transfer typically is to lower or raise temperatures in a device.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
2. CONTENT:
• Basic Definitions
• Natural And Force Convection
• Factor Affecting convective Heat Transfer Coefficient
• Nusselt Number And Prandlt Number
• Dimensional Relationship of Natural Convection With Gr and Pr
3. BASICS DEFINIONS
1. Heat Transfer:
Heat Transfer Define As The Transmission of Energy From One Region to another Region
as a result of Temperature Gradient.
• Conduction:
Conduction Transfer Heat via Direct Molecular Collision. Area of Greater kinetic energy will
Transfer Thermal energy to an area with lower kinetic energy.
• Convection:
When a Fluid, such as air or Liquid, is heated and then travels away
from the source, it carries the thermal energy along. This type of Heat
Transfer is called convection.
• Radiation:
Thermal Radiation Generates from the emission of electromagnetic
waves. These waves carry the energy away from the emitting object.
4. Natural And Force Convection
• Natural Convection is a type of heat transfer, in which the fluid motion is not generated by
any external source (like a pump, fan, suction pump etc.) but only by density differences in the
fluid occurring due to temperature gradients.
• The Example of free convection is a heated plate when kept in an atmosphere, it gets cooled by air.
Here the circulation of air take place due to density difference, which is caused by temperature
difference between solid plate and air.
• Natural convection is the process of heat transfer which occurs due to movement of the fluid
particles by density change associated with temperature differential in a fluid.
• Some Example are given below:
1.The cooling of electrical transformers and
rectifiers.
2. The heat transfer from hot pipes by cooled air .
5. • Forced convection is a type of transfer in which fluid motion is generated by an external
source (like a pump, fan, suction device, etc.)
• It is mostly used in all heat transfer application because the convection due to it, will be much higher
as compared to free convection.
• If a heated plate is kept under a fan for cooling, it is called as forced convection.
6. Factor Affecting convective Heat Transfer Coefficient
1. Temperature Difference (T)
T the greater the heat transfer rate.
2. Fluid flow rate
Increasing flow rate increasing heat transfer rate.
3. Surface area
the larger the surface area of conducting interfaces, the greater the heat
transfer rate.