Vowel combinations in English can involve two or three vowels appearing together or a vowel paired with one or more consonants. These combinations, called digraphs, diphthongs, and trigraphs, represent single sounds. Common digraphs include "ea", "ai", and "igh". There are also eight primary diphthongs in English like "ay" and "ow". Trigraphs combine three vowel sounds like "eai" and "iou". Proper understanding of these vowel combinations is important for learning to read and write in English.